If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




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SCHEDULE 13D




Comment for Type of Reporting Person:
This Reporting Person's Table is for Class A common stock. Rows 7 and 9 consists of (i) 2,568,443 shares of Class A common stock of Quantum-Si Incorporated (the ''Issuer'') held by Jonathan M. Rothberg, Ph.D., (ii) stock options to purchase 669,737 shares of Class A common stock of the Issuer which are exercisable within 60 days of August 26, 2026, held by Dr. Jonathan M. Rothberg and (iii) an aggregate of 8,947,746 shares of Class A common stock of the Issuer held by entities owned by trusts created for the benefit of Dr. Jonathan Rothberg's children. Rows 8 and 10 consists of (i) 1,917,067 shares of Class A common stock of the Issuer held by 23rd Century Capital LLC, and (ii) 273,422 shares of Class A common stock of the Issuer held by Dr. Jonathan Rothberg's spouse, Bonnie E. Gould Rothberg, M.D. Row 13 is calculated based on 198,946,412 shares of Class A common stock of the Issuer outstanding as of August 11, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
This Reporting Person's Table is for Class B common stock. Rows 7 and 9 consists of (i) 17,943,750 shares of Class B common stock of the Issuer held by 4C Holdings I, LLC and (ii) 1,993,750 shares of Class B common stock of the Issuer held by 4C Holdings V, LLC. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of August 11, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
This Reporting Person's table is for Class A common stock. Row 13 is calculated based on 198,946,412 shares of Class A common stock of the Issuer outstanding as of August 11, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
This Reporting Person's table is for Class B common stock. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of August 11, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
This Reporting Person's table is for Class B common stock. Row 13 is calculated based on 19,937,500 shares of Class B common stock of the Issuer outstanding as of August 11, 2026.


SCHEDULE 13D


 
ROTHBERG JONATHAN M
 
Signature:/s/ Jonathan M. Rothberg
Name/Title:Jonathan M. Rothberg, Ph.D.
Date:08/28/2026
 
ROTHBERG JONATHAN M.
 
Signature:/s/ Jonathan M. Rothberg
Name/Title:Jonathan M. Rothberg, Ph.D.
Date:08/28/2026
 
23rd Century Capital LLC
 
Signature:/s/ Jonathan M. Rothberg
Name/Title:Jonathan M. Rothberg, Ph.D., Member
Date:08/28/2026
 
4C Holdings I, LLC
 
Signature:/s/ Jonathan M. Rothberg
Name/Title:Jonathan M. Rothberg, Ph.D., Manager
Date:08/28/2026
 
4C Holdings V, LLC
 
Signature:/s/ Jonathan M. Rothberg
Name/Title:Jonathan M. Rothberg, Ph.D., Manager
Date:08/28/2026

ATTACHMENTS / EXHIBITS

ATTACHMENTS / EXHIBITS

EXHIBIT 6