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Note 11 - Related Party Transactions (Details Textual)	1 Months Ended	3 Months Ended
Note 11 - Related Party Transactions (Details Textual)	Jan. 31, 2024 USD ($)	Mar. 31, 2026 USD ($)	Mar. 31, 2025 USD ($)	Dec. 31, 2025	Aug. 01, 2024 USD ($) a	Jul. 31, 2024 a	Jan. 09, 2024 USD ($)	May 04, 2023 USD ($)	Jan. 31, 2013 USD ($)
Related Party Transaction [Line Items]
Debt Instrument, Face Amount									$ 175,000,000
Beckman Coulter [Member]
Related Party Transaction [Line Items]
Related Party Transaction, Amounts of Transaction		$ 353,000
Integrated DNA Technologies Inc. [Member]
Related Party Transaction [Line Items]
Related Party Transaction, Amounts of Transaction		4,000
Leica Microsystems Inc. [Member]
Related Party Transaction [Line Items]
Related Party Transaction, Amounts of Transaction		$ 193,000
Ruen-Hui Biopharmaceuticals, Inc. [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage								10.00%
Ruen-Hui Biopharmaceuticals, Inc. [Member] \| License Agreement [Member]
Related Party Transaction [Line Items]
Collaborative Arrangement, Upfront Payments								$ 150,000
Collaborative Arrangement, Maximum Regulatory Milestone Payments								$ 1,000,000
Pharmsynthez [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		6.00%
Xenetic [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		3.00%
Zebra [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		29.00%
Niagen [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		0.04%
COCP [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		2.00%
NIMS [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		1.00%
Eloxx [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		1.00%
LeaderMed [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage		47.00%
GeneDx [Member]
Related Party Transaction [Line Items]
Equity Method Investment, Ownership Percentage				2.20%
The 2029 Convertible Notes 1 [Member]
Related Party Transaction [Line Items]
Debt Instrument, Face Amount							$ 230,000,000
The 2029 Convertible Notes 1 [Member] \| Convertible Debt [Member]
Related Party Transaction [Line Items]
Debt Instrument, Issued, Principal	$ 71,100,000
The 2023 Convertible Notes [Member]
Related Party Transaction [Line Items]
Interest Payable	16,100,000
The 2023 Convertible Notes [Member] \| Convertible Debt [Member]
Related Party Transaction [Line Items]
Debt Instrument, Face Amount	$ 55,000,000
Frost Real Estate Holdings, LLC [Member]
Related Party Transaction [Line Items]
Area of Real Estate Property (Acre) \| a					26,328	29,500
Operating Leases, Monthly Payments, Year One					$ 91,000
Operating Leases, Monthly Payments, Year Five					$ 103,000
Executive Officer [Member] \| Reimbursement of Travel Expenses [Member]
Related Party Transaction [Line Items]
Related Party Transaction, Amounts of Transaction		$ 0	$ 0