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      </invstOrSec>
      <invstOrSec>
        <name>BRIDGEBIO PHARMA INC</name>
        <lei>54930028YG89VTY2J114</lei>
        <title>BRIDGEBIO PHARMA INC COM</title>
        <cusip>10806X102</cusip>
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          <isin value="US10806X1028"/>
          <ticker value="BBIO"/>
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        <balance>13129.00000000</balance>
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        <curCd>USD</curCd>
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      </invstOrSec>
      <invstOrSec>
        <name>THERMO FISHER SCIENTIFIC INC</name>
        <lei>HCHV7422L5HDJZCRFL38</lei>
        <title>THERMO FISHER SCIENTIFIC INC COM</title>
        <cusip>883556102</cusip>
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          <isin value="US8835561023"/>
          <ticker value="TMO"/>
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        <balance>421.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>211072.56000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>GRAIL INC</name>
        <lei>2549009XSNESW3VE8024</lei>
        <title>GRAIL INC COM</title>
        <cusip>384747101</cusip>
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          <isin value="US3847471014"/>
          <ticker value="GRAL"/>
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        <balance>4456.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>304211.12000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>TWIST BIOSCIENCE CORP</name>
        <lei>549300T23BL59LCOH584</lei>
        <title>TWIST BIOSCIENCE CORP COM</title>
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        <identifiers>
          <isin value="US90184D1000"/>
          <ticker value="TWST"/>
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        <balance>7736.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>795879.68000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>DANAHER CORP</name>
        <lei>S4BKK9OTCEWQ3YHPFM11</lei>
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          <isin value="US2358511028"/>
          <ticker value="DHR"/>
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        <balance>842.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>160384.16000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RHYTHM PHARMACEUTICALS INC</name>
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        <title>RHYTHM PHARMACEUTICALS INC COM</title>
        <cusip>76243J105</cusip>
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          <isin value="US76243J1051"/>
          <ticker value="RYTM"/>
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        <balance>1048.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>116359.44000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NEUROCRINE BIOSCIENCES INC</name>
        <lei>549300FECER0XBN49756</lei>
        <title>NEUROCRINE BIOSCIENCES INC COM</title>
        <cusip>64125C109</cusip>
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          <isin value="US64125C1099"/>
          <ticker value="NBIX"/>
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        <balance>3058.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>515380.03000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>LIGAND PHARMACEUTICALS INC</name>
        <lei>5493008K7TB0IKP37H79</lei>
        <title>LIGAND PHARMACEUTICALS INC COM NEW</title>
        <cusip>53220K504</cusip>
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          <isin value="US53220K5048"/>
          <ticker value="LGND"/>
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        <balance>4085.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1291227.65000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CAREDX INC</name>
        <lei>549300NQOFKL9NON0U06</lei>
        <title>CAREDX INC COM</title>
        <cusip>14167L103</cusip>
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          <isin value="US14167L1035"/>
          <ticker value="CDNA"/>
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        <balance>8000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>228000.00000000</valUSD>
        <pctVal>0.816135213089</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SARTORIUS AG</name>
        <lei>529900EQV2DY4FOAMU38</lei>
        <title>SARTORIUS AG NON VTG PFD NPV</title>
        <cusip>000000000</cusip>
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          <isin value="DE0007165631"/>
          <ticker value="SRT3"/>
          <other otherDesc="SEDOL" value="5843329"/>
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        <balance>905.00000000</balance>
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        <currencyConditional curCd="EUR" exchangeRt="0.87466100"/>
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        <pctVal>0.850370080736</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>BIONTECH SE</name>
        <lei>894500UZJ5LG1F8J1U58</lei>
        <title>BIONTECH SE SPONSORED ADS</title>
        <cusip>09075V102</cusip>
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          <isin value="US09075V1026"/>
          <ticker value="BNTX"/>
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        <balance>4156.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>386715.80000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>KRYSTAL BIOTECH INC</name>
        <lei>549300YONUY68210OE41</lei>
        <title>KRYSTAL BIOTECH INC COM</title>
        <cusip>501147102</cusip>
        <identifiers>
          <isin value="US5011471027"/>
          <ticker value="KRYS"/>
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        <balance>4757.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1768034.19000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>TG THERAPEUTICS INC</name>
        <lei>529900X21UKABN9NJ529</lei>
        <title>TG THERAPEUTICS INC COM</title>
        <cusip>88322Q108</cusip>
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          <isin value="US88322Q1085"/>
          <ticker value="TGTX"/>
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        <balance>1253.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>68839.82000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>KINIKSA PHARMACEUTICALS INTERNATIONAL PLC</name>
        <lei>N/A</lei>
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        <cusip>000000000</cusip>
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          <isin value="GB00BRXB0C07"/>
          <ticker value="KNSA"/>
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        <balance>1479.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>94582.05000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>UNITED THERAPEUTICS CORP</name>
        <lei>5299005C4HZL4UWROC14</lei>
        <title>UNITED THERAPEUTICS CORP COM</title>
        <cusip>91307C102</cusip>
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          <isin value="US91307C1027"/>
          <ticker value="UTHR"/>
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        <balance>1809.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>980170.47000000</valUSD>
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        <assetCat>EC</assetCat>
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      <invstOrSec>
        <name>ASTRAZENECA PLC</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>ASTRAZENECA PLC ORD USD0.25</title>
        <cusip>000000000</cusip>
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          <isin value="GB0009895292"/>
          <ticker value="AZN"/>
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        <balance>3979.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>754497.98000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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        <name>LIQUIDIA CORP</name>
        <lei>549300O826O5VQJTG707</lei>
        <title>LIQUIDIA CORP COM NEW</title>
        <cusip>53635D202</cusip>
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          <isin value="US53635D2027"/>
          <ticker value="LQDA"/>
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        <curCd>USD</curCd>
        <valUSD>69444.83000000</valUSD>
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        <assetCat>EC</assetCat>
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      <invstOrSec>
        <name>IONIS PHARMACEUTICALS INC</name>
        <lei>549300SI4ZGLG0BLUZ92</lei>
        <title>IONIS PHARMACEUTICALS INC COM</title>
        <cusip>462222100</cusip>
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          <isin value="US4622221004"/>
          <ticker value="IONS"/>
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        <curCd>USD</curCd>
        <valUSD>534335.31000000</valUSD>
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        <assetCat>EC</assetCat>
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        <name>ELI LILLY &amp; COMPANY</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>ELI LILLY &amp; COMPANY COM</title>
        <cusip>532457108</cusip>
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          <isin value="US5324571083"/>
          <ticker value="LLY"/>
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        <curCd>USD</curCd>
        <valUSD>825207.84000000</valUSD>
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        <assetCat>EC</assetCat>
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          <isLoanByFund>N</isLoanByFund>
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        <name>VERACYTE INC</name>
        <lei>529900ESWZRHXOW27Z37</lei>
        <title>VERACYTE INC COM</title>
        <cusip>92337F107</cusip>
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          <isin value="US92337F1075"/>
          <ticker value="VCYT"/>
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        <balance>7819.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>459209.87000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <name>REGENERON PHARMACEUTICALS INC</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>REGENERON PHARMACEUTICALS INC COM</title>
        <cusip>75886F107</cusip>
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          <isin value="US75886F1075"/>
          <ticker value="REGN"/>
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        <balance>805.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>501949.70000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>ANAPTYSBIO INC</name>
        <lei>529900HH4WQT03IG1A12</lei>
        <title>ANAPTYSBIO INC COM</title>
        <cusip>032724106</cusip>
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          <isin value="US0327241065"/>
          <ticker value="ANAB"/>
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        <balance>4290.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>289575.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>AGILENT TECHNOLOGIES INC</name>
        <lei>QUIX8Y7A2WP0XRMW7G29</lei>
        <title>AGILENT TECHNOLOGIES INC COM</title>
        <cusip>00846U101</cusip>
        <identifiers>
          <isin value="US00846U1016"/>
          <ticker value="A"/>
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        <balance>1223.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>162451.09000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
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      </invstOrSec>
      <invstOrSec>
        <name>GENEDX HOLDINGS CORP</name>
        <lei>N/A</lei>
        <title>GENEDX HOLDINGS CORP COM CL A</title>
        <cusip>81663L200</cusip>
        <identifiers>
          <isin value="US81663L2007"/>
          <ticker value="WGS"/>
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        <balance>575.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>39473.75000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>STOKE THERAPEUTICS INC</name>
        <lei>549300RD25SS2DIJHJ67</lei>
        <title>STOKE THERAPEUTICS INC COM</title>
        <cusip>86150R107</cusip>
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          <isin value="US86150R1077"/>
          <ticker value="STOK"/>
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        <balance>11349.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>371339.28000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>PTC THERAPEUTICS INC</name>
        <lei>549300UJLWOIWFDGB318</lei>
        <title>PTC THERAPEUTICS INC COM</title>
        <cusip>69366J200</cusip>
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          <isin value="US69366J2006"/>
          <ticker value="PTCT"/>
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        <balance>5009.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>408584.13000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIO-RAD LABORATORIES INC</name>
        <lei>549300ZC1GPV35XYDK53</lei>
        <title>BIO-RAD LABORATORIES INC CL A</title>
        <cusip>090572207</cusip>
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          <isin value="US0905722072"/>
          <ticker value="BIO"/>
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        <balance>243.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>71347.23000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BEAM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>BEAM THERAPEUTICS INC COM</title>
        <cusip>07373V105</cusip>
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          <isin value="US07373V1052"/>
          <ticker value="BEAM"/>
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        <balance>7577.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>260042.64000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BRISTOL-MYERS SQUIBB COMPANY</name>
        <lei>HLYYNH7UQUORYSJQCN42</lei>
        <title>BRISTOL-MYERS SQUIBB COMPANY COM</title>
        <cusip>110122108</cusip>
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          <isin value="US1101221083"/>
          <ticker value="BMY"/>
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        <balance>1196.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>68913.52000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC COM</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
          <ticker value="VRTX"/>
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        <balance>1545.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>767447.85000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>BEONE MEDICINES LTD</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD SPONSORED ADS</title>
        <cusip>07725L102</cusip>
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          <isin value="US07725L1026"/>
          <ticker value="ONC"/>
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        <balance>225.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>64118.25000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>CRISPR THERAPEUTICS AG</name>
        <lei>506700O6IRRIQLT3W370</lei>
        <title>CRISPR THERAPEUTICS AG NAMEN AKT</title>
        <cusip>000000000</cusip>
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          <isin value="CH0334081137"/>
          <ticker value="CRSP"/>
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        <balance>5030.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>274336.20000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>FIRST TRACKS BIOTHERAPEUTICS INC</name>
        <lei>529900CGIGKN4R5RO925</lei>
        <title>FIRST TRACKS BIOTHERAPEUTICS INC ORD SHS</title>
        <cusip>337185102</cusip>
        <identifiers>
          <isin value="US3371851029"/>
          <ticker value="TRAX"/>
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        <balance>2775.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>55833.00000000</valUSD>
        <pctVal>0.199856479615</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>OMNIAB INC</name>
        <lei>N/A</lei>
        <title>OMNIAB INC USD0.0001 A (USD12.5 VESTING)</title>
        <cusip>68218J202</cusip>
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          <isin value="US68218J2024"/>
          <ticker value="2200963D"/>
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        <balance>240.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NEUROGENE INC</name>
        <lei>529900A7VIY892SZVW73</lei>
        <title>NEUROGENE INC COM</title>
        <cusip>64135M105</cusip>
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          <isin value="US64135M1053"/>
          <ticker value="NGNE"/>
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        <balance>1981.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>62302.45000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TARSUS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>TARSUS PHARMACEUTICALS INC COM</title>
        <cusip>87650L103</cusip>
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          <isin value="US87650L1035"/>
          <ticker value="TARS"/>
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        <balance>1136.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>71499.84000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TEMPUS AI INC</name>
        <lei>2549009LA0KWRAGQBX50</lei>
        <title>TEMPUS AI INC CL A</title>
        <cusip>88023B103</cusip>
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          <isin value="US88023B1035"/>
          <ticker value="TEM"/>
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        <balance>9397.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>544368.21000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RECURSION PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>RECURSION PHARMACEUTICALS INC CL A</title>
        <cusip>75629V104</cusip>
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          <isin value="US75629V1044"/>
          <ticker value="RXRX"/>
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        <balance>5507.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>20210.69000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SAMSUNG BIOLOGICS CO LTD</name>
        <lei>N/A</lei>
        <title>SAMSUNG BIOLOGICS CO LTD KRW2500</title>
        <cusip>000000000</cusip>
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          <isin value="KR7207940008"/>
          <ticker value="207940"/>
          <other otherDesc="SEDOL" value="BYNJCV6"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
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          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
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      <invstOrSec>
        <name>CORTEVA INC</name>
        <lei>549300WZN9I2QKLS0O94</lei>
        <title>CORTEVA INC COM</title>
        <cusip>22052L104</cusip>
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          <isin value="US22052L1044"/>
          <ticker value="CTVA"/>
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        <balance>7435.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>629670.15000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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      <invstOrSec>
        <name>ARCUTIS BIOTHERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ARCUTIS BIOTHERAPEUTICS INC COM</title>
        <cusip>03969K108</cusip>
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          <isin value="US03969K1088"/>
          <ticker value="ARQT"/>
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        <balance>4422.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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      <invstOrSec>
        <name>PRAXIS PRECISION MEDICINES INC</name>
        <lei>N/A</lei>
        <title>PRAXIS PRECISION MEDICINES INC COM NEW</title>
        <cusip>74006W207</cusip>
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          <ticker value="PRAX"/>
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        <balance>718.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>240379.22000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>JAZZ PHARMACEUTICALS PLC</name>
        <lei>635400GAUMJCLEZRRV50</lei>
        <title>JAZZ PHARMACEUTICALS PLC SHS USD</title>
        <cusip>000000000</cusip>
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          <isin value="IE00B4Q5ZN47"/>
          <ticker value="JAZZ"/>
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        <balance>905.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>218077.85000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>WAVE LIFE SCIENCES LTD</name>
        <lei>54930070006GPKFYZ813</lei>
        <title>WAVE LIFE SCIENCES LTD SHS</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="SG9999014716"/>
          <ticker value="WVE"/>
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        <balance>4813.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>27963.53000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>SG</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>GUARDANT HEALTH INC</name>
        <lei>254900M8C3E5VC8BR186</lei>
        <title>GUARDANT HEALTH INC COM</title>
        <cusip>40131M109</cusip>
        <identifiers>
          <isin value="US40131M1099"/>
          <ticker value="GH"/>
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        <balance>16927.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2539557.81000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>SAMSUNG EPIS HOLDINGS CO LTD</name>
        <lei>N/A</lei>
        <title>SAMSUNG EPIS HOLDINGS CO LTD KRW2500</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="KR70126Z0002"/>
          <ticker value="0126Z0"/>
          <other otherDesc="SEDOL" value="BW9LVP9"/>
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        <balance>376.00000000</balance>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALNYLAM PHARMACEUTICALS INC</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>ALNYLAM PHARMACEUTICALS INC COM</title>
        <cusip>02043Q107</cusip>
        <identifiers>
          <isin value="US02043Q1076"/>
          <ticker value="ALNY"/>
        </identifiers>
        <balance>1816.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>546670.48000000</valUSD>
        <pctVal>1.956829073178</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATERA INC</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>NATERA INC COM</title>
        <cusip>632307104</cusip>
        <identifiers>
          <isin value="US6323071042"/>
          <ticker value="NTRA"/>
        </identifiers>
        <balance>7679.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2084464.55000000</valUSD>
        <pctVal>7.461425086369</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADAPTIVE BIOTECHNOLOGIES CORP</name>
        <lei>549300ZTF7OT1FW66Q96</lei>
        <title>ADAPTIVE BIOTECHNOLOGIES CORP COM</title>
        <cusip>00650F109</cusip>
        <identifiers>
          <isin value="US00650F1093"/>
          <ticker value="ADPT"/>
        </identifiers>
        <balance>51956.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1114456.20000000</valUSD>
        <pctVal>3.989241001167</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSMED INC</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>INSMED INC COM PAR $.01</title>
        <cusip>457669307</cusip>
        <identifiers>
          <isin value="US4576693075"/>
          <ticker value="INSM"/>
        </identifiers>
        <balance>6388.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>681088.56000000</valUSD>
        <pctVal>2.437984022142</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TRAVERE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>TRAVERE THERAPEUTICS INC COM</title>
        <cusip>89422G107</cusip>
        <identifiers>
          <isin value="US89422G1076"/>
          <ticker value="TVTX"/>
        </identifiers>
        <balance>12753.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>724497.93000000</valUSD>
        <pctVal>2.593369616156</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OMNIAB INC</name>
        <lei>N/A</lei>
        <title>OMNIAB INC USD0.0001 A (USD15 VESTING)</title>
        <cusip>68218J301</cusip>
        <identifiers>
          <isin value="US68218J3014"/>
          <ticker value="2200964D"/>
        </identifiers>
        <balance>240.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.00000000</valUSD>
        <pctVal>0.000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>QIAGEN NV</name>
        <lei>54930036WK3GMCN17Z57</lei>
        <title>QIAGEN NV ORD SHARES</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL0015002SN0"/>
          <ticker value="QGEN"/>
        </identifiers>
        <balance>3419.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>133682.90000000</valUSD>
        <pctVal>0.478523342447</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHARLES RIVER LABORATORIES INTERNATIONAL INC</name>
        <lei>549300BSQ0R4UZ5KX287</lei>
        <title>CHARLES RIVER LABORATORIES INTERNATIONAL INC COM</title>
        <cusip>159864107</cusip>
        <identifiers>
          <isin value="US1598641074"/>
          <ticker value="CRL"/>
        </identifiers>
        <balance>1556.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>352885.24000000</valUSD>
        <pctVal>1.263166976068</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CATALYST PHARMACEUTICALS INC</name>
        <lei>5299004O0R5XXLA5H544</lei>
        <title>CATALYST PHARMACEUTICALS INC COM</title>
        <cusip>14888U101</cusip>
        <identifiers>
          <isin value="US14888U1016"/>
          <ticker value="CPRX"/>
        </identifiers>
        <balance>6865.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>215766.95000000</valUSD>
        <pctVal>0.772346516298</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CADENCE DESIGN SYSTEMS INC</name>
        <lei>GCT7RXJOGLXPV0NXZY22</lei>
        <title>CADENCE DESIGN SYSTEMS INC COM</title>
        <cusip>127387108</cusip>
        <identifiers>
          <isin value="US1273871087"/>
          <ticker value="CDNS"/>
        </identifiers>
        <balance>725.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>272107.00000000</valUSD>
        <pctVal>0.974018001878</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HINGE HEALTH INC</name>
        <lei>N/A</lei>
        <title>HINGE HEALTH INC CL A</title>
        <cusip>433313103</cusip>
        <identifiers>
          <isin value="US4333131039"/>
          <ticker value="HNGE"/>
        </identifiers>
        <balance>2349.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>194967.00000000</valUSD>
        <pctVal>0.697892254782</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>
        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      
      
      
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-08-25</ncom:dateSigned>
      <ncom:nameOfApplicant>Franklin Templeton ETF Trust</ncom:nameOfApplicant>
      <ncom:signature>Monica Krogh</ncom:signature>
      <ncom:signerName>Monica Krogh</ncom:signerName>
      <ncom:title>Assistant Treasurer Controller, US Fund Administration and Oversight</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
