v3.26.1
Summary of material accounting policies - Revenue (Details)
€ in Millions
1 Months Ended 12 Months Ended
Oct. 31, 2019
USD ($)
Oct. 12, 2018
USD ($)
Jun. 30, 2022
USD ($)
Feb. 28, 2020
USD ($)
Dec. 31, 2019
USD ($)
Oct. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2022
EUR (€)
Dec. 31, 2017
EUR (€)
Disclosure of summary of significant accounting policies                          
Revenue recognized from up-front payment as deferred consideration       $ 10,000,000.0                  
Receipt on non refundable up-front payment upon reaching product regulatory milestone               $ 25,000,000.0          
Number of escalating milestone payments           6              
Royalty revenue               5,097,000 $ 5,935,000 $ 5,902,000      
Product sales, net               $ 115,153,000 $ 11,263,000 $ 0      
Percentage of gross sales               86.60% 85.40% 0.00%      
Total gross to net adjustments                          
Disclosure of summary of significant accounting policies                          
Product sales, net               $ (17,737,000) $ (1,929,000) $ 0      
Percentage of gross sales               13.40% 14.60% 0.00%      
Grunenthal                          
Disclosure of summary of significant accounting policies                          
Non-refundable upfront payment received $ 15,000,000.0   $ 17,500,000                    
Milestone payment received         $ 2,500,000                
Cumulative milestone payments reachable amount     1,000,000,000                    
Revenue recognized relation to patent license agreement               $ 0 $ 0 $ 0      
Grunenthal | Top of range | Clinical, manufacturing, regulatory and reimbursement approval                          
Disclosure of summary of significant accounting policies                          
Non-refundable upfront payments receivable     $ 112,500,000                    
Tasly                          
Disclosure of summary of significant accounting policies                          
Deferred consideration milestone consideration recognized   $ 20,000,000.0       $ 20,000,000.0              
Revenue recognized from up-front payment as deferred consideration   $ 10,000,000.0           0 0 0      
TiGenix NV                          
Disclosure of summary of significant accounting policies                          
Milestone revenue in relation to patent license agreement             $ 5,900,000 $ 0 0 0 $ 1,200,000    
Regulatory milestone payment receivable | €                       € 1.0 € 5.0
Royalty revenue                 100,000 400,000      
TiGenix NV | Top of range                          
Disclosure of summary of significant accounting policies                          
Milestone revenue relating to non-refundable up-front payment | €                         € 9.0
J C R Pharmaceuticals Co L T D                          
Disclosure of summary of significant accounting policies                          
Profit sharing percentage               50.00%          
Royalties receivable under sales-based milestones               $ 5,100,000 $ 5,800,000 $ 5,500,000