| Loss before income tax |
Loss before income tax | | | | | | | | | | | | | | | | | | | | | | | | | | | Year Ended June 30, | | (in U.S. dollars, in thousands) | Note | | 2026 | | 2025 | | 2024 | | Revenue | | | | | | | | Product sales, net(1) | | | 115,153 | | | 11,263 | | | — | | | Royalty revenue | | | 5,097 | | | 5,935 | | | 5,902 | | | Total Revenue | | | 120,250 | | | 17,198 | | | 5,902 | | | | | | | | | | | Cost of revenues | | | | | | | | | Cost of inventories | | | (10,541) | | | (1,193) | | | — | | | Amortization of currently marketed intangible assets | | | (6,126) | | | (3,937) | | | — | | | Total Cost of revenues | | | (16,667) | | | (5,130) | | | — | | | | | | | | | | | Clinical trial and research & development | | | (30,521) | | | (8,070) | | | (3,308) | | | Manufacturing production & development | | | (32,693) | | | 6,323 | | | (13,252) | | | Commercialization | | | (15,869) | | | (4,676) | | | (655) | | | | | | | | | | | Employee benefits | | | | | | | | | Salaries and employee benefits | | | (28,095) | | | (22,092) | | | (20,415) | | | Defined contribution superannuation expenses | | | (510) | | | (395) | | | (369) | | Equity settled share-based payment transactions(2) | | | (14,873) | | | (22,088) | | | (5,870) | | | Total Employee benefits | | | (43,478) | | | (44,575) | | | (26,654) | | | | | | | | | | | Depreciation and amortization of non-current assets | | | | | | | | | Plant and equipment depreciation | | | (481) | | | (303) | | | (410) | | | Right of use asset depreciation | | | (1,942) | | | (2,139) | | | (2,771) | | | Intellectual property amortization | | | (36) | | | (21) | | | (1,485) | | | Total Depreciation and amortization of non-current assets | | | (2,459) | | | (2,463) | | | (4,666) | | | | | | | | | | | Other Selling, general and administration | | | | | | | | | Overheads & administration | | | (13,855) | | | (10,168) | | | (8,584) | | | Consultancy | | | (4,795) | | | (2,728) | | | (2,458) | | | Legal, patent and other professional fees | | | (6,192) | | | (4,335) | | | (2,342) | | | Intellectual property expenses (excluding the amount amortized above) | | | (4,993) | | | (3,424) | | | (2,777) | | | Total Other Selling, general and administration | | | (29,835) | | | (20,655) | | | (16,161) | | | | | | | | | | | Fair value remeasurement of contingent consideration | | | | | | | | | Remeasurement of financial derivative | | | 7,892 | | | (10,262) | | | — | | | Remeasurement of contingent consideration | | | 4,165 | | | (4,625) | | | (9,693) | | | Total Fair value remeasurement of contingent consideration | 5(f)(iii) | | 12,057 | | | (14,887) | | | (9,693) | | | | | | | | | | | Fair value remeasurement of warrant liability | | | | | | | | | Remeasurement of warrant liability | 5(f)(vi) | | 859 | | | (4,962) | | | 779 | | | Total Fair value remeasurement of warrant liability | | | 859 | | | (4,962) | | | 779 | | | | | | | | | | | Other operating income and expenses | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | Year Ended June 30, | | (in U.S. dollars, in thousands) | Note | | 2026 | | 2025 | | 2024 | | Interest income | | | 3,914 | | | 3,554 | | | 1,824 | | | Research and development tax incentive income | | | — | | | 82 | | | 859 | | | Government grant revenue | | | 22 | | | 3 | | | — | | | Foreign exchange gains/(losses) | | | 1,069 | | | (106) | | | (76) | | | Derecognition of lease liability | | | 388 | | | — | | | — | | | Derecognition of right-of-use asset | | | (85) | | | — | | | — | | | Foreign withholding tax paid | | | — | | | (480) | | | (37) | | | Total Other operating income and expenses | | | 5,308 | | | 3,053 | | | 2,570 | | | | | | | | | | | Finance (costs)/gains | | | | | | | | | Remeasurement of borrowing arrangements | | | (1,965) | | | (416) | | | (2,351) | | | Interest expense | | | (19,872) | | | (21,753) | | | (20,658) | | | Facility fee | | | (2,002) | | | (799) | | | — | | | Total Finance costs | | | (23,839) | | | (22,968) | | | (23,009) | | | | | | | | | | | Total loss before income tax | | | (56,887) | | | (101,812) | | | (88,147) | |
(1) Revenue from product sales Product revenues are recorded net of allowances for variable consideration such as estimated government rebates and chargebacks, distribution fees, distributor and off-label discounts, patient assistance programs, freight and packaging costs and returns. See Note 22(e)(ii) for the Group's policy regarding revenue from product sales. Product revenues consist of the following: | | | | | | | | | | | | | | | | | | | Year Ended June 30, | | (in U.S. dollars, in thousands) | 2026 | | 2025 | | 2024 | Ryoncil® | 115,153 | | | 11,263 | | | — | |
As at June 30, 2026 and June 30, 2025, the Group’s trade receivables, net were $57.1 million and $13.9 million, which relate to product sales, net of discounts and allowances. The revenue from net product sales is derived from a single external customer which exceeded 10% of the Group's total revenue. Refer to Note 10(b) for discussion of the credit risk associated with trade receivables. The following table summarizes gross product sales to net product sales by significant category of gross to net adjustments for the years ended June 30, 2026, 2025 and 2024. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Year Ended June 30, | | (in U.S. dollars, in thousands) | 2026 | | % of gross sales 2026 | | 2025 | | % of gross sales 2025 | | 2024 | | % of gross sales 2024 | | Gross product sales | 132,890 | | | 100.0 | % | | 13,192 | | | 100.0 | % | | — | | | — | % | | Gross to net adjustments | | | | | | | | | | | | | Government rebates and chargebacks | (13,439) | | | 10.2 | % | | (1,489) | | | 11.3 | % | | — | | | — | % | | Discounts and distributor fees | (1,876) | | | 1.4 | % | | (171) | | | 1.3 | % | | — | | | — | % | | Other sales-related deductions | (2,422) | | | 1.8 | % | | (265) | | | 2.0 | % | | — | | | — | % | | Co-pay assistance | — | | | — | % | | (4) | | | — | % | | — | | | — | % | | Total gross to net adjustments | (17,737) | | | 13.4 | % | | (1,929) | | | 14.6 | % | | — | | | — | % | | Product sales, net | 115,153 | | | 86.6 | % | | 11,263 | | | 85.4 | % | | — | | | — | % |
Gross to net adjustments are estimated using contractual terms, statutory requirements, actual claims and settlement experience, patient and payer mix, channel data and other information available at the reporting date. The Group regularly evaluates its estimates against actual results. Accruals for chargebacks are recorded as a direct reduction to trade receivables. Accruals for government rebates, distribution fees, distributor and off-label discounts, patient assistance programs and freight are recorded within trade and other payables. The following table summarizes the gross to net adjustments and payments, including sales-related deductions: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | (in U.S. dollars, in thousands) | Government rebates and chargebacks | | Discounts and distributor fees | | Other sales-related deductions | | Co-pay assistance | | Total | | Balance as of July 1, 2023 | — | | | — | | | — | | | — | | | — | | | Gross to net adjustments | — | | | — | | | — | | | — | | | — | | | Payments | — | | | — | | | — | | | — | | | — | | | Balance as at June 30, 2024 | — | | | — | | | — | | | — | | | — | | | | | | | | | | | | | Balance as of July 1, 2024 | — | | | — | | | — | | | — | | | — | | | Gross to net adjustments | 1,489 | | | 171 | | | 265 | | | 4 | | | 1,929 | | | Payments | — | | | (50) | | | (47) | | | — | | | (97) | | | Balance as at June 30, 2025 | 1,489 | | | 121 | | | 218 | | | 4 | | | 1,832 | | | | | | | | | | | | | Balance as of July 1, 2025 | 1,489 | | | 121 | | | 218 | | | 4 | | | 1,832 | | | Gross to net adjustments | 13,439 | | | 1,876 | | | 2,422 | | | — | | | 17,737 | | | Payments | (3,143) | | | (1,323) | | | (667) | | | — | | | (5,133) | | | Balance as at June 30, 2026 | 11,785 | | | 674 | | | 1,973 | | | 4 | | | 14,436 | |
(2) Share-based payment transactions For the years ended June 30, 2026, 2025 and 2024, share-based payment transactions have been reflected in the Consolidated Income Statement functional expense categories as follows: | | | | | | | | | | | | | | | | | | | Year Ended June 30, | | (in U.S. dollars) | 2026 | | 2025 | | 2024 | | Research and development | 7,360,087 | | | 12,487,004 | | | 2,950,104 | | | Selling, general and administration | 7,512,853 | | | 9,601,283 | | | 2,920,064 | | | Equity settled share-based payment transactions | 14,872,940 | | | 22,088,287 | | | 5,870,168 | |
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