v3.26.1
STOCKHOLDERS' EQUITY (Tables)
6 Months Ended 12 Months Ended
Jun. 30, 2026
Dec. 31, 2025
Equity [Abstract]    
Summary of Share-based Compensation
Share-based compensation is comprised of the Company’s stock options, restricted stock awards, restricted stock units and shares issued pursuant to the employee stock purchase plan, and is classified in the condensed consolidated statements of operations and comprehensive income (loss) for the three and six months ended June 30, 2026 and 2025 was as follows:
 
    
 FOR THE THREE MONTHS ENDED
JUNE 30,
      
FOR THE SIX MONTHS ENDED
JUNE 30,
 
(in thousands)
  
2026
    
2025
      
2026
    
2025
 
Research and development
  
$
35
  
$
618
    
$
219
  
$
1,428
General and administrative
    
389
    
996
      
818
    
2,065
  
 
 
    
 
 
      
 
 
    
 
 
 
  
$
424
  
$
1,614
    
$
1,037
  
$
3,493
  
 
 
    
 
 
      
 
 
    
 
 
 
Share-based compensation is comprised of the Company’s stock options, restricted stock awards, restricted stock units and shares issued pursuant to the employee stock purchase plan, and is classified in the consolidated statements of operations and comprehensive loss for the years ended December 31, 2025 and 2024 and was as follows:
 
    
FOR THE YEAR ENDED
DECEMBER 31,
 
(in thousands)
  
  2025  
    
  2024  
 
Research and development
   $ 2,250      $ 3,269  
General and administrative
     3,064        4,724  
  
 
 
    
 
 
 
   $ 5,314      $ 7,993  
  
 
 
    
 
 
 
Summary of Stock Option Activity
The following table summarizes stock option activity for the six months ended June 30, 2026:
 

Stock Options
  
Number of
Option Shares
 
 
Weighted-
Average
Exercise Price
 
  
Weighted-
Average
Contractual
Term
(in years)
 
  
Aggregate
Intrinsic Value
(in thousands)
 
Outstanding stock options at December 31, 2025
    
628,280
 
 
$
43.42
 
    
7.6
 
  
$
89
 
Granted
    
32,360
 
 
$
4.45
 
     
Forfeited
    
(11,404
 
$
15.70
 
     
Expired
    
(13,317
)
 
$
93.52
 
     
Exercised
    
(14,087
)
 
$
8.56
 
     
  
 
 
         
Outstanding stock options at June 30, 2026
    
621,832
 
 
$
41.62
 
    
3.1
 
  
$
2,348
 
  
 
 
         
Exercisable stock options at June 30, 2026
    
456,345
 
 
$
51.43
 
    
2.6
 
  
$
1,260
 
  
 
 
         
The following table summarizes stock option activity for the year ended December 31, 2025:
 
Stock Options
  
Number of
Option Shares
   
Weighted-
Average
Exercise Price
    
Weighted-
Average
Contractual
Term

(in years)
    
Aggregate
Intrinsic
Value

(in thousands)
 
Outstanding stock options at December 31, 2024
     529,342     $ 62.83        7.8      $  
Granted
     224,179     $ 5.87        
Forfeited
     (51,758   $ 32.54        
Expired
     (73,483   $ 76.34        
Exercised
     —      $ —         
  
 
 
         
Outstanding at December 31, 2025
     628,280     $ 43.42        7.6      $ 89  
  
 
 
         
Exercisable stock options at December 31, 2025
     399,047     $ 58.72        7.1      $ —   
  
 
 
         
Summary of Assumptions of Fair Value of Option Pricing Granted
The fair value of the stock options granted during the six months ended June 30, 2026 and 2025 was determined using the Black-Scholes option pricing model with the following assumptions:
 
    
FOR THE SIX MONTHS ENDED
JUNE 30,
 
    
 2026 
    
 2025 
 
Expected volatility
    
109.21%
      
91.88%–119.61%
 
Expected term (years)
    
5.25
      
5.27–6.02
 
Risk free interest rate
    
3.68%
      
4.03%–4.39%
 
Expected dividend yield
    
— 
      
— 
 
Exercise price
  
$
4.45
    
$
2.40–$7.60 
 
The fair value of the stock options granted during the years ended December 31, 2025 and 2024 was determined using the Black-Scholes option pricing model with the following assumptions:
 
    
FOR THE YEAR ENDED DECEMBER 31,
 
    
2025
    
2024
 
Expected volatility
    
91.88% - 119.61%
      
89.41% - 94.48%
 
Expected term (years)
     5.27 - 6.02        5.50 - 6.02  
Risk free interest rate
    
4.03
% - 4.39%
       3.93% - 4.35%  
Expected dividend yield
     —         —   
Exercise price
   $ 2.38 - $7.60      $ 14.88 - $19.20  
Summary of Unvested Restricted Common Stock Awards  
A summary of the status of the Company’s nonvested restricted common stock awards at December 31, 2025 and changes during the year ended December 31, 2025 was as follows:
 
Restricted Stock Awards
  
Shares
   
Weighted-
Average Grant
Date Fair Value
Per Share
 
Nonvested restricted common stock awards at December 31, 2024
     2,687     $ 31.76  
Granted
     —      $ —   
Vested
     (2,687   $ 31.76  
Forfeited
     —      $ —   
  
 
 
   
Nonvested restricted common stock awards at December 31, 2025
     —      $ —   
  
 
 
   
Summary of Unvested Restricted Common Stock Units
A summary of the status of the Company’s nonvested restricted common stock units at June 30, 2026 and changes during the six months ended June 30, 2026 was as follows:
 

Restricted Stock Units
  
Shares
 
 
Weighted-
Average Grant
Date Fair
Value Per Share
 
Nonvested restricted stock units at December 31, 2025
    
38,603
   
$
9.60
 
Granted
    
5,000
   
$
4.45
 
Forfeited
    
(4,150
 
$
2.40
 
Vested
    
(6,684
)
 
$
9.53
 
  
 
 
   
 
 
 
Nonvested restricted stock units at
June
 3
0
, 2026
    
32,769
   
$
9.74
 
  
 
 
   
 
 
 
A summary of the status of the Company’s nonvested restricted common stock units at December 31, 2025 and changes during the year ended December 31, 2025 was as follows:
 
Restricted Stock Units
  
Shares
   
Weighted-
Average Grant
Date Fair Value
Per Share
 
Nonvested restricted common stock units at December 31, 2024
     133,069     $ 18.89  
Granted
     59,500     $ 5.96  
Forfeited
     (66,646   $ 12.34  
Vested
     (87,320   $ 19.18  
  
 
 
   
Nonvested restricted common stock units at December 31, 2025
     38,603     $ 9.60