<?xml version="1.0" encoding="UTF-8"?>
<edgarSubmission xmlns:com="http://www.sec.gov/edgar/common" xmlns="http://www.sec.gov/edgar/npx">
  <headerData>
    <submissionType>N-PX</submissionType>
    <filerInfo>
      <registrantType>IM</registrantType>
      <liveTestFlag>LIVE</liveTestFlag>
      <filer>
        <issuerCredentials>
          <cik>0001467728</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>
      <periodOfReport>06/30/2026</periodOfReport>
    </filerInfo>
  </headerData>
  <formData>
    <coverPage>
      <yearOrQuarter>YEAR</yearOrQuarter>
      <reportCalendarYear>2026</reportCalendarYear>
      <reportingPerson>
        <name>WELLS FARGO INVESTMENT INSTITUTE, INC.</name>
        <phoneNumber>908-565-6193</phoneNumber>
        <address>
          <com:street1>550 SOUTH TRYON</com:street1>
          <com:street2>40TH FLOOR</com:street2>
          <com:city>Charlotte</com:city>
          <com:stateOrCountry>NC</com:stateOrCountry>
          <com:zipCode>28202</com:zipCode>
        </address>
      </reportingPerson>
      <reportInfo>
        <reportType>INSTITUTIONAL MANAGER NOTICE REPORT</reportType>
        <noticeExplanation>ALL VOTES BY OTHER PERSONS</noticeExplanation>
        <confidentialTreatment>N</confidentialTreatment>
      </reportInfo>
      <fileNumber>028-22080</fileNumber>
      <reportingCrdNumber>000133204</reportingCrdNumber>
      <reportingSecFileNumber>801-64191</reportingSecFileNumber>
      <otherManagersInfo>
        <otherManager>
          <icaOr13FFileNumber>028-13117</icaOr13FFileNumber>
          <crdNumber>000011025</crdNumber>
          <otherFileNumber>8-28721</otherFileNumber>
          <managerName>WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC</managerName>
        </otherManager>
        <otherManager>
          <icaOr13FFileNumber>028-01341</icaOr13FFileNumber>
          <managerName>WELLS FARGO BANK N A</managerName>
        </otherManager>
        <otherManager>
          <icaOr13FFileNumber>028-13118</icaOr13FFileNumber>
          <crdNumber>000019616</crdNumber>
          <otherFileNumber>8-37180</otherFileNumber>
          <managerName>WELLS FARGO CLEARING SERVICES, LLC</managerName>
        </otherManager>
        <otherManager>
          <icaOr13FFileNumber>028-12628</icaOr13FFileNumber>
          <managerName>WELLS FARGO DELAWARE TRUST CO, N.A.</managerName>
        </otherManager>
      </otherManagersInfo>
      <explanatoryInformation>
        <explanatoryChoice>N</explanatoryChoice>
      </explanatoryInformation>
    </coverPage>
    <signaturePage>
      <reportingPerson>WELLS FARGO INVESTMENT INSTITUTE, INC.</reportingPerson>
      <txSignature>Thomas J. Wald</txSignature>
      <txPrintedSignature>Thomas J. Wald</txPrintedSignature>
      <txTitle>Wealth Investment Portfolio Management Director</txTitle>
      <txAsOfDate>08/20/2026</txAsOfDate>
    </signaturePage>
  </formData>
</edgarSubmission>
