Exhibit 99.2

 

1. Clinical Efficacy of Ion-Peptide Adjunctive Therapy in Patients with Solid Tumors

 

No. Name Sex Age (years) Diagnosis Before Treatment   1 Month After Treatment   3 Months After Treatment   6 Months After Treatment
Respiratory Gastrointestinal   Respiratory Gastrointestinal   Respiratory Gastrointestinal   Respiratory Gastrointestinal
1 Wu Junbo Male 23 Lung cancer with brain metastasis Irritative choking cough, dyspnea, and chest tightness None   Irritative choking cough, dyspnea, and chest tightness resolved None   No chest tightness or dyspnea; no cough or sputum production. None   No chest tightness or dyspnea; no cough or sputum production. None
2 Jin Deshui Male 72 Lung cancer with mediastinal metastasis Mild cough and sputum production, accompanied by chest tightness and discomfort. None   Cough resolved; slight sputum production remained; chest tightness and discomfort resolved. None   No cough, sputum production, or chest tightness. None   No cough, sputum production, or chest tightness. None
3 Chen Jianzhong Male 71 Rectal cancer None Mild abdominal pain and distension, with alternating constipation and diarrhea.   None Mild abdominal pain and distension improved; no alternating constipation and diarrhea.   None No abdominal pain or distension; no constipation or diarrhea.   None No abdominal pain or distension; no constipation or diarrhea.
4 Liu Quandang Male 78 Advanced lung cancer and advanced COPD Marked cough and sputum production, with pronounced dyspnea, chest tightness, and palpitations. None   Mild cough and moderate sputum production; dyspnea and chest tightness improved; palpitations resolved. None   Mild cough and sputum production; dyspnea and chest tightness improved; no palpitations. None   Mild cough and sputum production; dyspnea and chest tightness improved. None
5 Chen Jiangna Female 34 Malignant lymphoma No cough or sputum production; chest tightness and palpitations, accompanied by low- to moderate-grade fever. Mild abdominal distension, no diarrhea, and poor appetite.   No obvious respiratory symptoms, but chest tightness and palpitations were present, with irregular low- to moderate-grade fever. Mild abdominal distension, no diarrhea, and poor appetite.   Chest tightness and palpitations persisted, as did irregular low- to moderate-grade fever. Abdominal distension decreased; no diarrhea; poor appetite.   Chest tightness and palpitations persisted, with irregular low-grade fever. Mild abdominal distension, no diarrhea, and poor appetite.
6 Zhang Haixiang Female 58 Left upper-lobe lung cancer with obstructive pneumonia Moderate-grade fever and marked cough with sputum production, accompanied by dyspnea and chest tightness; no palpitations. None   Occasional low-grade fever; cough and sputum production decreased, with dyspnea and chest tightness. None   No fever; mild cough without sputum production; dyspnea and chest tightness persisted. None   No fever, cough, or sputum production; dyspnea and chest tightness improved. None
7 Zhao Pingni Female 64 Diffuse lung cancer Marked cough and sputum production, with dyspnea and palpitations. None   Predominantly cough and dyspnea, accompanied by palpitations, chest tightness, and fatigue. None   Cough and dyspnea remained predominant; accompanying palpitations, chest tightness, and fatigue improved. None   Cough and dyspnea decreased; palpitations and chest tightness persisted; no fatigue. None
8 Zhang Chun Male 65 Advanced liver cancer with respiratory failure Advanced liver cancer with extensive lung metastases, causing extreme dyspnea and respiratory failure. Massive ascites with abdominal distension and pain; cachectic state.   Extreme dyspnea further worsened; respiratory failure accompanied by heart failure. Massive ascites progressively worsened, with persistent abdominal distension and pain; cachexia worsened.   Deceased        
9 Zhao Pingxiao Male 81 Rectal cancer with lung metastasis, diabetes, and COPD Marked cough and sputum production with severe shortness of breath and dyspnea, cyanotic lips, and respiratory failure. Persistent marked abdominal distension and pain, pronounced poor appetite, and constipation.   Shortness of breath and dyspnea with extreme breathing difficulty and respiratory failure. Persistent marked abdominal distension and pain with massive ascites; extremely poor appetite and almost no food intake.   Deceased        
10 Gao Jun Female 39 Bronchiectasis Marked cough and sputum production; expectoration of bright-red blood, approximately 50 mL/day, with chest tightness, fatigue, and shortness of breath. None   Cough and sputum production markedly decreased; no hemoptysis; chest tightness, shortness of breath, and fatigue remained. None   Cough persisted; no sputum production or hemoptysis; chest tightness and fatigue, but no shortness of breath. None   Occasional cough; no sputum production, hemoptysis, shortness of breath, chest tightness, or fatigue. None

 

 

 

 

2. Changes in Vital Signs During Ion-Peptide Adjunctive Therapy in Patients with Solid Tumors

 

No. Name Sex Age (years) Diagnosis Before Treatment     1 Month After Treatment     3 Months After Treatment     6 Months After Treatment  
Respiratory Rate (breaths/min) Pulse (beats/min) Heart Rate (beats/min) Oxygen Saturation (SO2%) Blood Pressure (mmHg)   Respiratory Rate (breaths/min) Pulse (beats/min) Heart Rate (beats/min) SO2 (%) Blood Pressure (mmHg)   Respiratory Rate (breaths/min) Pulse (beats/min) Heart Rate (beats/min) SO2 (%) Blood Pressure (mmHg)   Respiratory Rate (breaths/min) Pulse (beats/min) Heart Rate (beats/min) SO2 (%) Blood Pressure (mmHg)
1 Wu Junbo Male 23 Lung cancer with brain metastasis 22 72 72 98 126/78   21 68 81 99 120/72   24 68 70 99 122/72   20 66 66 100 118/70
2 Jin Deshui Male 72 Lung cancer with mediastinal metastasis 21 84 84 95 138/88   24 90 81 94 140/78   26 80 80 95 129/78   22 78 77 94 139/85
3 Chen Jianzhong Male 71 Rectal cancer 24 82 82 98 140/86   19 77 78 98 138/76   22 76 77 97 134/84   24 74 74 98 140/88
4 Liu Quandang Male 78 Advanced lung cancer and advanced COPD 28 90 90 91 145/92   29 94 94 93 150/90   30 85 84 92 138/88   26 82 81 93 140/78
5 Chen Jiangna Female 34 Malignant lymphoma 26 86 86 96 138/87   30 91 91 96 138/82   24 80 78 97 127/77   20 82 84 96 136/82
6 Zhang Haixiang Female 58 Left upper-lobe lung cancer with obstructive pneumonia 28 90 90 96 150/90   27 94 94 92 146/94   24 88 86 92 142/84   22 84 83 93 138/82
7 Zhao Pingni Female 64 Diffuse lung cancer 27 78 78 92 146/87   30 84 84 94 142/90   22 72 72 95 136/82   23 70 69 94 142/87
8 Zhang Chun Male 65 Advanced liver cancer with respiratory failure 32 102 114 89 152/100   34 87 88 78 156/96     Deceased                  
9 Zhao Pingxiao Male 81 Rectal cancer with lung metastasis, diabetes, and COPD 34 111 111 90 149/96   36 99 105 74 149/96     Deceased                  
10 Gao Jun Female 39 Bronchiectasis 26 80 80   128/78   26 80 80 99 128/78   22 78 78 98 136/82   20 72 70 100 130/74

 

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3. Changes in Peripheral Blood Counts During Ion-Peptide Adjunctive Therapy in Patients with Solid Tumors

 

No. Name Sex Age (years) Diagnosis Before Treatment   1 Month After Treatment   3 Months After Treatment   6 Months After Treatment
WBC (×10⁹/L) Neutrophils (%) Lymphocytes (%)   WBC (×10⁹/L) Neutrophils (%) Lymphocytes (%)   WBC (×10⁹/L) Neutrophils (%) Lymphocytes (%)   WBC (×10⁹/L) Neutrophils (%) Lymphocytes (%)
1 Wu Junbo Male 23 Lung cancer with brain metastasis 5.8 58.1 21.4   6.1 64.3 32.1   6.4 59.8 33.3   5.8 61.4 31.8
2 Jin Deshui Male 72 Lung cancer with mediastinal metastasis 6.1 68.3 24.3   7.5 62.8 32.1   7.2 58.2 27.4   6.8 69.7 21.1
3 Chen Jianzhong Male 71 Rectal cancer 7.4 70.8 24.1   6.7 64.2 31.2   5.8 66.3 27.6   5.3 56.8 33.2
4 Liu Quandang Male 78 Advanced lung cancer and advanced COPD 9.5 80.4 12.2   6.2 72.1 22.7   6.2 78.1 20.5   5.9 70.5 27.5
5 Chen Jiangna Female 34 Malignant lymphoma 8.9 28.3 62.6   9.6 25.9 65.9   8.3 24.7 66.3   8.1 23.4 65.2
6 Zhang Haixiang Female 58 Left upper-lobe lung cancer with obstructive pneumonia 10.2 85.8 10.5   8.5 73.2 20.7   7.5 68.7 28.5   6.4 65.1 30.3
7 Zhao Pingni Female 64 Diffuse lung cancer 12.3 82.3 11.2   8.2 70.5 23.7   6.5 67.4 31.4   7.6 70.2 29.5
8 Zhang Chun Male 65 Advanced liver cancer with respiratory failure 11.2 88.1 9.4   13.4 90.5 8.7   Deceased            
9 Zhao Pingxiao Male 81 Rectal cancer with lung metastasis, diabetes, and COPD 14.2 90.2 8.7   18.7 91.6 7.1   Deceased            
10 Gao Jun Female 39 Bronchiectasis 8.1 56.5 23.7   6.9 59.8 29.1   5.7 56.2 30.2   6.1 57.2 27.9

 

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4. Changes in Lipid Profile During Ion-Peptide Adjunctive Therapy in Patients with Solid Tumors (Unit: mol/L)

 

No. Name Sex Age (years) Diagnosis Before Treatment   1 Month After Treatment   3 Months After Treatment   6 Months After Treatment
Total Cholesterol (TC) Triglycerides (TG) HDL Cholesterol (HDL-C) LDL Cholesterol (LDL-C)   TC TG HDL-C LDL-C   TC TG HDL-C LDL-C   TC TG HDL-C LDL-C
1 Wu Junbo Male 23 Lung cancer with brain metastasis 4.2 1.5 2.3 2.9   3.8 1.6 2.0 3.2   5.2 1.2 1.8 2.8   4.8 1.6 3.2 2.3
2 Jin Deshui Male 72 Lung cancer with mediastinal metastasis 3.8 2.3 1.1 3.1   4.1 2.8 1.4 2.9   4.9 1.8 2.0 3.2   5.1 2.1 3.6 2.7
3 Chen Jianzhong Male 71 Rectal cancer 4.4 2.6 1.4 2.9   3.8 2.2 1.6 3.3   4.6 1.7 1.7 3.5   4.9 2.3 2.5 3.1
4 Liu Quandang Male 78 Advanced lung cancer and advanced COPD 5.0 1.8 1.6 3.8   4.8 2.4 1.3 4.2   5.0 2.1 1.9 3.8   3.9 1.8 2.4 3.2
5 Chen Jiangna Female 34 Malignant lymphoma 3.4 2.1 1.4 2.7   3.5 3.1 1.7 3.1   5.3 2.3 2.1 3.4   5.2 1.9 2.6 2.9
6 Zhang Haixiang Female 58 Left upper-lobe lung cancer with obstructive pneumonia 5.6 1.7 1.7 2.5   4.9 1.6 1.5 3.3   4.8 1.8 1.7 4.0   5.0 1.6 2.9 3.7
7 Zhao Pingni Female 64 Diffuse lung cancer 3.4 2.2 1.2 2.7   3.1 1.8 1.7 2.9   5.3 2.2 2.0 3.5   5.5 2.4 2.2 4.1
8 Zhang Chun Male 65 Advanced liver cancer with respiratory failure 6.1 3.1 1.0 4.1   7.4 2.9 1.2 5.1   Deceased                
9 Zhao Pingxiao Male 81 Rectal cancer with lung metastasis, diabetes, and COPD 2.8 1.4 1.5 4.4   2.6 1.6 1.2 5.8   Deceased                
10 Gao Jun Female 39 Bronchiectasis 4.5 1.6 1.6 3.1   3.9 1.7 2.1 2.9   4.5 1.7 2.1 2.9   3.9 1.4 1.6 3.0

 

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5. Changes in Immune Cells During Ion-Peptide Adjunctive Therapy in Patients with Solid Tumors

 

No. Name Sex Age (years) Diagnosis Before Treatment (%)   1 Month After Treatment (%)   3 Months After Treatment (%)   6 Months After Treatment (%)
CD3+CD8⁺ CD16+CD56⁺   CD3+CD8⁺ CD16+CD56⁺   CD3+CD8⁺ CD16+CD56⁺   CD3+CD8⁺ CD16+CD56⁺
1 Wu Junbo Male 23 Lung cancer with brain metastasis 79.83 16.94   32.33 48.30   26.32 88.58   83.44 79.98
2 Jin Deshui Male 72 Lung cancer with mediastinal metastasis 57.11 25.36   66.34 72.71   42.29 63.81   64.77 78.31
3 Chen Jianzhong Male 71 Rectal cancer 39.12 12.22   79.37 79.28   65.18 74.11   48.07 88.93
4 Liu Quandang Male 78 Advanced lung cancer and advanced COPD 44.23 65.27   62.79 24.45   77.25 74.36   20.07 33.41
5 Chen Jiangna Female 34 Malignant lymphoma 63.88 24.82   38.61 57.26   72.51 76.53   59.31 53.14
6 Zhang Haixiang Female 58 Left upper-lobe lung cancer with obstructive pneumonia 34.08 58.36   68.34 65.66   75.89 45.27   54.23 81.37
7 Zhao Pingni Female 64 Diffuse lung cancer 54.08 31.72   80.64 84.49   62.84 76.76   46.03 79.01
8 Zhang Chun Male 65 Advanced liver cancer with respiratory failure 16.49 18.58   17.99 5.39   Deceased        
9 Zhao Pingxiao Male 81 Rectal cancer with lung metastasis, diabetes, and COPD 14.33 12.97   13.48 9.61   Deceased        
10 Gao Jun Female 39 Bronchiectasis 79.83 36.94   71.29 13.06   58.46 87.15   63.54 76.48

 

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