<?xml version='1.0' encoding='utf-8'?>
<inf:proxyVoteTable xmlns:inf="http://www.sec.gov/edgar/document/npxproxy/informationtable"><inf:proxyTable><inf:issuerName>ADAPTIVE BIOTECHNOLOGIES CORPORATION</inf:issuerName><inf:cusip>00650F109</inf:cusip><inf:isin>US00650F1093</inf:isin><inf:meetingDate>06/05/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of our named executive officers as described in the proxy statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>244846</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>244846</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ADMA BIOLOGICS, INC.</inf:issuerName><inf:cusip>000899104</inf:cusip><inf:isin>US0008991046</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>467233</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>467233</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>AKERO THERAPEUTICS, INC</inf:issuerName><inf:cusip>00973Y108</inf:cusip><inf:isin>US00973Y1082</inf:isin><inf:meetingDate>12/02/2025</inf:meetingDate><inf:voteDescription>To approve, on an advisory, non-binding basis, the payment of certain compensation that may be paid or become payable by Akero to its named executive officers in connection with the Merger. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>763523</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>763523</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>AMYLYX PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>03237H101</inf:cusip><inf:isin>US03237H1014</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>5695994</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>5695994</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>APOGEE THERAPEUTICS, INC.</inf:issuerName><inf:cusip>03770N101</inf:cusip><inf:isin>US03770N1019</inf:isin><inf:meetingDate>06/09/2026</inf:meetingDate><inf:voteDescription>Approval, on a non-binding advisory basis, of the compensation of our named executive officers as disclosed in the proxy statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>332549</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>332549</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ARTIVION, INC.</inf:issuerName><inf:cusip>228903100</inf:cusip><inf:isin>US2289031005</inf:isin><inf:meetingDate>05/12/2026</inf:meetingDate><inf:voteDescription>To approve, by non-binding vote, the compensation paid to Artivion's Named Executive Officers, as disclosed pursuant to Item 402 of Regulation S-K, including the Compensation Discussion and Analysis, compensation tables, and narrative discussion. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1415077</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1415077</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ASTRIA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>04635X102</inf:cusip><inf:isin>US04635X1028</inf:isin><inf:meetingDate>01/21/2026</inf:meetingDate><inf:voteDescription>To cast a vote, on a non-binding, advisory basis, to approve the Merger-related named executive officer compensation as disclosed in the table entitled "Golden Parachute Compensation" and its accompanying footnotes which is included in the section of the proxy statement entitled "The Merger-Interests of Astria's Directors and Executive Officers in the Merger," as required by Section 14A of the Securities Exchange Act of 1934, as amended, which was enacted as part of the Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>4460827</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>4460827</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>AVADEL PHARMACEUTICALS PLC</inf:issuerName><inf:cusip>G29687103</inf:cusip><inf:isin>IE00BDGMC594</inf:isin><inf:meetingDate>01/12/2026</inf:meetingDate><inf:voteDescription>Ordinary resolution to approve, on a non-binding, advisory basis, specified compensatory arrangements between Avadel and its named executive officers relating to the Transaction. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>99958</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>99958</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>AXOGEN, INC.</inf:issuerName><inf:cusip>05463X106</inf:cusip><inf:isin>US05463X1063</inf:isin><inf:meetingDate>06/23/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers as disclosed in the Company's Proxy Statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>425456</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>425456</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>AXSOME THERAPEUTICS, INC.</inf:issuerName><inf:cusip>05464T104</inf:cusip><inf:isin>US05464T1043</inf:isin><inf:meetingDate>06/05/2026</inf:meetingDate><inf:voteDescription>To approve, by non-binding advisory vote, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>9971</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>9971</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>BIOCRYST PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>09058V103</inf:cusip><inf:isin>US09058V1035</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To hold a non-binding, advisory vote regarding executive compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>3950268</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>3950268</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>BIODESIX, INC.</inf:issuerName><inf:cusip>09075X207</inf:cusip><inf:isin>US09075X2071</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>108694</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>108694</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>BIODESIX, INC.</inf:issuerName><inf:cusip>09075X207</inf:cusip><inf:isin>US09075X2071</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the frequency of solicitation of advisory votes to approve named executive officer compensation.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>108694</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>108694</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>BOSTON SCIENTIFIC CORPORATION</inf:issuerName><inf:cusip>101137107</inf:cusip><inf:isin>US1011371077</inf:isin><inf:meetingDate>04/30/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>77455</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>77455</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CELCUITY INC.</inf:issuerName><inf:cusip>15102K100</inf:cusip><inf:isin>US15102K1007</inf:isin><inf:meetingDate>05/14/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, named executive officer compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1847565</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1847565</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>COGENT BIOSCIENCES, INC.</inf:issuerName><inf:cusip>19240Q201</inf:cusip><inf:isin>US19240Q2012</inf:isin><inf:meetingDate>06/09/2026</inf:meetingDate><inf:voteDescription>Approval, on a non-binding, advisory basis, of the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>15677</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>15677</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CORCEPT THERAPEUTICS INCORPORATED</inf:issuerName><inf:cusip>218352102</inf:cusip><inf:isin>US2183521028</inf:isin><inf:meetingDate>05/21/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the company's named executive officers as disclosed in the accompanying proxy statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>163726</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>163726</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CORVUS PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>221015100</inf:cusip><inf:isin>US2210151005</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1255921</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1255921</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CRESCENT BIOPHARMA, INC.</inf:issuerName><inf:cusip>G2545C104</inf:cusip><inf:isin>KYG2545C1042</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of Crescent Biopharma, Inc.'s named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>206942</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>206942</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CRESCENT BIOPHARMA, INC.</inf:issuerName><inf:cusip>G2545C104</inf:cusip><inf:isin>KYG2545C1042</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To vote, on a non-binding advisory basis, on the frequency of future advisory votes to approve compensation for Crescent Biopharma, Inc.'s named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>206942</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>206942</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CUMBERLAND PHARMACEUTICALS INC.</inf:issuerName><inf:cusip>230770109</inf:cusip><inf:isin>US2307701092</inf:isin><inf:meetingDate>04/21/2026</inf:meetingDate><inf:voteDescription>To provide advisory approval of the compensation of the Company's named executive officers, as disclosed pursuant to Item 402 of Regulation S-K, including the Compensation Discussion and Analysis, compensation tables and narrative discussion. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>333572</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>333572</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CUMBERLAND PHARMACEUTICALS INC.</inf:issuerName><inf:cusip>230770109</inf:cusip><inf:isin>US2307701092</inf:isin><inf:meetingDate>04/21/2026</inf:meetingDate><inf:voteDescription>To provide advisory approval of the frequency of the advisory vote on the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>333572</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>333572</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CYTOMX THERAPEUTICS, INC.</inf:issuerName><inf:cusip>23284F105</inf:cusip><inf:isin>US23284F1057</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To approve, on a nonbinding advisory basis, the compensation of the Company's named executive officers as disclosed in the Proxy Statement accompanying this Notice of Annual Meeting of Stockholders. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6669055</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>6669055</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>CYTOMX THERAPEUTICS, INC.</inf:issuerName><inf:cusip>23284F105</inf:cusip><inf:isin>US23284F1057</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To hold a non-binding advisory vote on the frequency of future advisory votes by stockholders on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6669055</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>6669055</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>DAMORA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>36322Q206</inf:cusip><inf:isin>US36322Q2066</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1104066</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1104066</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>DAMORA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>36322Q206</inf:cusip><inf:isin>US36322Q2066</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To conduct an advisory vote to determine the frequency of future advisory votes on the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1104066</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1104066</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>DYNE THERAPEUTICS, INC.</inf:issuerName><inf:cusip>26818M108</inf:cusip><inf:isin>US26818M1080</inf:isin><inf:meetingDate>06/05/2026</inf:meetingDate><inf:voteDescription>To vote, on an advisory basis, to approve the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1023597</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1023597</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>EDESA BIOTECH INC</inf:issuerName><inf:cusip>27966L306</inf:cusip><inf:isin>CA27966L3065</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>Advisory Vote on Executive Compensation: Approve, on an advisory basis, our executive compensation ("Say on Pay"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>561522</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>561522</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>EDGEWISE THERAPEUTICS INC</inf:issuerName><inf:cusip>28036F105</inf:cusip><inf:isin>US28036F1057</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>Conduct an advisory vote on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2432969</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2432969</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>EVOLUS, INC.</inf:issuerName><inf:cusip>30052C107</inf:cusip><inf:isin>US30052C1071</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>Approval of, on an advisory basis, the compensation of Evolus' named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1279253</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1279253</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>EXACT SCIENCES CORPORATION</inf:issuerName><inf:cusip>30063P105</inf:cusip><inf:isin>US30063P1057</inf:isin><inf:meetingDate>02/20/2026</inf:meetingDate><inf:voteDescription>Proposal to approve, on an advisory (nonbinding) basis, the compensation that may be paid or become payable to Exact Sciences Corporation's named executive officers that is based on or otherwise related to the Merger Agreement and the transactions contemplated by the Merger Agreement (the "Compensation Proposal"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>583428</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>583428</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>EXAGEN INC</inf:issuerName><inf:cusip>30068X103</inf:cusip><inf:isin>US30068X1037</inf:isin><inf:meetingDate>06/09/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>114893</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>114893</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>GUARDANT HEALTH, INC.</inf:issuerName><inf:cusip>40131M109</inf:cusip><inf:isin>US40131M1099</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>Non-binding advisory vote to approve Guardant Health, Inc.'s named executive officer compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6007</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>6007</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>GUARDANT HEALTH, INC.</inf:issuerName><inf:cusip>40131M109</inf:cusip><inf:isin>US40131M1099</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>Non-binding advisory vote on the frequency of stockholder advisory votes regarding compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6007</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>6007</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>IMMUNOVANT, INC.</inf:issuerName><inf:cusip>45258J102</inf:cusip><inf:isin>US45258J1025</inf:isin><inf:meetingDate>08/27/2025</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>129258</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>129258</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>INTUITIVE SURGICAL, INC.</inf:issuerName><inf:cusip>46120E602</inf:cusip><inf:isin>US46120E6023</inf:isin><inf:meetingDate>04/30/2026</inf:meetingDate><inf:voteDescription>To approve, by advisory vote, the compensation of the Company's Named Executive Officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>16490</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>16490</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>IONIS PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>462222100</inf:cusip><inf:isin>US4622221004</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To make an advisory vote on executive compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>21367</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>21367</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>IOVANCE BIOTHERAPEUTICS, INC.</inf:issuerName><inf:cusip>462260100</inf:cusip><inf:isin>US4622601007</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>To approve, by non-binding advisory vote, the compensation of our namedexecutive offi cers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2500</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2500</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>IRHYTHM HOLDINGS, INC.</inf:issuerName><inf:cusip>450056106</inf:cusip><inf:isin>US4500561067</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the named executive officer compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>13560</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>13560</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>LEONABIO, INC.</inf:issuerName><inf:cusip>04746L203</inf:cusip><inf:isin>US04746L2034</inf:isin><inf:meetingDate>06/22/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1858060</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1858060</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>LEONABIO, INC.</inf:issuerName><inf:cusip>04746L203</inf:cusip><inf:isin>US04746L2034</inf:isin><inf:meetingDate>06/22/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the frequency of future stockholder advisory votes on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1858060</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1858060</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>MEDLINE INC.</inf:issuerName><inf:cusip>58507V107</inf:cusip><inf:isin>US58507V1070</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>Advisory Vote to Approve Our Executive Compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>28000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>28000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>MEDLINE INC.</inf:issuerName><inf:cusip>58507V107</inf:cusip><inf:isin>US58507V1070</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>Advisory Vote on the Frequency of Votes on Our Executive Compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>28000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>28000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>MERUS N.V.</inf:issuerName><inf:cusip>N5749R100</inf:cusip><inf:isin>NL0011606264</inf:isin><inf:meetingDate>12/09/2025</inf:meetingDate><inf:voteDescription>Non-binding advisory proposal to approve certain compensation arrangements </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1288218</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1288218</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NATERA, INC.</inf:issuerName><inf:cusip>632307104</inf:cusip><inf:isin>US6323071042</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1716</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1716</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NATERA, INC.</inf:issuerName><inf:cusip>632307104</inf:cusip><inf:isin>US6323071042</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the frequency of future advisory votes on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1716</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1716</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NAUTILUS BIOTECHNOLOGY, INC.</inf:issuerName><inf:cusip>63909J108</inf:cusip><inf:isin>US63909J1088</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>Approval on an advisory basis of the compensation of our named executive officers for the fiscal year ended December 31, 2025 (the "Say on Pay Vote"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11889327</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>11889327</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NAUTILUS BIOTECHNOLOGY, INC.</inf:issuerName><inf:cusip>63909J108</inf:cusip><inf:isin>US63909J1088</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>Approval on an advisory basis of the frequency of future Say on Pay Votes. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11889327</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>11889327</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NEUMORA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>640979100</inf:cusip><inf:isin>US6409791000</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>Advisory vote on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>4288471</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>4288471</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NEUMORA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>640979100</inf:cusip><inf:isin>US6409791000</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>Advisory vote on the frequency of future advisory votes on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>4288471</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>4288471</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NEUROCRINE BIOSCIENCES, INC.</inf:issuerName><inf:cusip>64125C109</inf:cusip><inf:isin>US64125C1099</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>Advisory vote on the compensation paid to the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>65050</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>65050</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NURIX THERAPEUTICS, INC.</inf:issuerName><inf:cusip>67080M103</inf:cusip><inf:isin>US67080M1036</inf:isin><inf:meetingDate>05/15/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of the Company's named executive officers as disclosed in the Proxy Statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2307270</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2307270</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>NUVALENT, INC.</inf:issuerName><inf:cusip>670703107</inf:cusip><inf:isin>US6707031075</inf:isin><inf:meetingDate>06/16/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation paid to our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>537743</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>537743</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>OPUS GENETICS, INC.</inf:issuerName><inf:cusip>67577R102</inf:cusip><inf:isin>US67577R1023</inf:isin><inf:meetingDate>04/20/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory basis, of the compensation of the Company's named executive officers </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2642969</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2642969</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ORCHESTRA BIOMED HOLDINGS, INC.</inf:issuerName><inf:cusip>68572M106</inf:cusip><inf:isin>US68572M1062</inf:isin><inf:meetingDate>06/23/2026</inf:meetingDate><inf:voteDescription>Adoption of an advisory (non-binding) resolution approving the compensation of our "named executive officers". </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2869489</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2869489</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ORCHESTRA BIOMED HOLDINGS, INC.</inf:issuerName><inf:cusip>68572M106</inf:cusip><inf:isin>US68572M1062</inf:isin><inf:meetingDate>06/23/2026</inf:meetingDate><inf:voteDescription>Advisory (non-binding) vote on the frequency of future advisory (non-binding) votes on the compensation of our "named executive officers". </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2869489</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2869489</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ORUKA THERAPEUTICS, INC.</inf:issuerName><inf:cusip>687604108</inf:cusip><inf:isin>US6876041087</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1076829</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1076829</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>OSCAR HEALTH, INC.</inf:issuerName><inf:cusip>687793109</inf:cusip><inf:isin>US6877931096</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>Advisory vote to approve named executive officer compensation ("Say-on-Pay"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>7062</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>7062</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>PALISADE BIO, INC.</inf:issuerName><inf:cusip>696389402</inf:cusip><inf:isin>US6963894026</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding advisory basis, the compensation of our named executive officers, as disclosed in the proxy statement. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>9505065</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>9505065</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>PHATHOM PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>71722W107</inf:cusip><inf:isin>US71722W1071</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>To approve the compensation of the named executive officers on a non-binding advisory basis ("say-on-pay"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>694522</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>694522</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>PRAXIS PRECISION MEDICINES, INC.</inf:issuerName><inf:cusip>74006W207</inf:cusip><inf:isin>US74006W2070</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2026 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the Compensation Discussion and Analysis, the compensation tables and narrative discussion. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1752527</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1752527</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>PROTAGONIST THERAPEUTICS, INC.</inf:issuerName><inf:cusip>74366E102</inf:cusip><inf:isin>US74366E1029</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>64701</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>64701</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>RELAY THERAPEUTICS, INC.</inf:issuerName><inf:cusip>75943R102</inf:cusip><inf:isin>US75943R1023</inf:isin><inf:meetingDate>06/09/2026</inf:meetingDate><inf:voteDescription>To consider and act upon an advisory vote on the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>7756504</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>7756504</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>REPLIGEN CORPORATION</inf:issuerName><inf:cusip>759916109</inf:cusip><inf:isin>US7599161095</inf:isin><inf:meetingDate>05/14/2026</inf:meetingDate><inf:voteDescription>Advisory vote to approve the compensation paid to Repligen Corporation's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>330</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>330</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>REVOLUTION MEDICINES, INC.</inf:issuerName><inf:cusip>76155X100</inf:cusip><inf:isin>US76155X1000</inf:isin><inf:meetingDate>06/18/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers as disclosed in the Proxy Statement pursuant to the compensation disclosure rules of the Securities and Exchange Commission ("Say-on-Pay"). </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>291054</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>291054</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>RHYTHM PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>76243J105</inf:cusip><inf:isin>US76243J1051</inf:isin><inf:meetingDate>06/24/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory (non-binding) basis, of the compensation of the named executive officers of the Company. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1505179</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1505179</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ROIVANT SCIENCES LTD.</inf:issuerName><inf:cusip>G76279101</inf:cusip><inf:isin>BMG762791017</inf:isin><inf:meetingDate>09/10/2025</inf:meetingDate><inf:voteDescription>To cast a non-binding, advisory vote to approve the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>3162948</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>3162948</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>SOLID BIOSCIENCES INC.</inf:issuerName><inf:cusip>83422E204</inf:cusip><inf:isin>US83422E2046</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>The approval of an advisory vote on executive compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11055900</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>11055900</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>SPYRE THERAPEUTICS INC.</inf:issuerName><inf:cusip>00773J202</inf:cusip><inf:isin>US00773J2024</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2587491</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2587491</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>SURROZEN, INC.</inf:issuerName><inf:cusip>86889P208</inf:cusip><inf:isin>US86889P2083</inf:isin><inf:meetingDate>05/13/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory basis, of the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>202900</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>202900</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>SURROZEN, INC.</inf:issuerName><inf:cusip>86889P208</inf:cusip><inf:isin>US86889P2083</inf:isin><inf:meetingDate>05/13/2026</inf:meetingDate><inf:voteDescription>Advisory vote on the preferred frequency of the advisory vote on the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>202900</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>202900</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>SUTRO BIOPHARMA, INC.</inf:issuerName><inf:cusip>869367201</inf:cusip><inf:isin>US8693672011</inf:isin><inf:meetingDate>06/05/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>714753</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>714753</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>TANGO THERAPEUTICS, INC.</inf:issuerName><inf:cusip>87583X109</inf:cusip><inf:isin>US87583X1090</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1118577</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1118577</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>TRAVERE THERAPEUTICS, INC.</inf:issuerName><inf:cusip>89422G107</inf:cusip><inf:isin>US89422G1076</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2381160</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2381160</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>TRAVERE THERAPEUTICS, INC.</inf:issuerName><inf:cusip>89422G107</inf:cusip><inf:isin>US89422G1076</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2381160</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2381160</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>VERONA PHARMA PLC</inf:issuerName><inf:cusip>925050106</inf:cusip><inf:isin>US9250501064</inf:isin><inf:meetingDate>09/24/2025</inf:meetingDate><inf:voteDescription>To approve, on an advisory, non-binding basis, the compensation that may be paid or become payable to the Company's named executive officers in connection with the Transaction, as disclosed in the table entitled "Potential Payments to Named Executive Officers" beginning on page 70 of the proxy statement, including the associated narrative discussion, and the agreements or understandings pursuant to which such compensation may be paid or become payable. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2873554</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2873554</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>VERONA PHARMA PLC</inf:issuerName><inf:cusip>925050106</inf:cusip><inf:isin>US9250501064</inf:isin><inf:meetingDate>09/24/2025</inf:meetingDate><inf:voteDescription>To approve, on an advisory, non-binding basis, the compensation that may be paid or become payable to the Company's named executive officers in connection with the Transaction, as disclosed in the table entitled "Potential Payments to Named Executive Officers" beginning on page 70 of the proxy statement, including the associated narrative discussion, and the agreements or understandings pursuant to which such compensation may be paid or become payable. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>493000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>493000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>VIRIDIAN THERAPEUTICS, INC.</inf:issuerName><inf:cusip>92790C104</inf:cusip><inf:isin>US92790C1045</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>686669</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>686669</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>VIRIDIAN THERAPEUTICS, INC.</inf:issuerName><inf:cusip>92790C104</inf:cusip><inf:isin>US92790C1045</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the frequency of holding an advisory vote on the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>686669</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>686669</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>X4 PHARMACEUTICALS, INC.</inf:issuerName><inf:cusip>98420X202</inf:cusip><inf:isin>US98420X2027</inf:isin><inf:meetingDate>05/11/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6314452</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>6314452</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>ZYMEWORKS INC.</inf:issuerName><inf:cusip>98985Y108</inf:cusip><inf:isin>US98985Y1082</inf:isin><inf:meetingDate>12/30/2025</inf:meetingDate><inf:voteDescription>Advisory vote on the compensation of our named executive officers </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>654545</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>654545</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable><inf:proxyTable><inf:issuerName>VYOME HOLDINGS, INC</inf:issuerName><inf:cusip>92943X104</inf:cusip><inf:isin>US92943X1046</inf:isin><inf:meetingDate>10/28/2025</inf:meetingDate><inf:voteDescription>Approve the advisory, non-binding vote on executive compensation. </inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>0</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ABSTAIN</inf:howVoted><inf:sharesVoted>0</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote><inf:voteManager><inf:otherManagers><inf:otherManager>0</inf:otherManager></inf:otherManagers></inf:voteManager></inf:proxyTable></inf:proxyVoteTable>
