Exhibit 99.2
PRESS RELEASE
Immatics Announces Second Quarter 2026
Financial Results and Business Update

Exhibit 99.2
PRESS RELEASE
Immatics Announces Second Quarter 2026
Financial Results and Business Update
Immatics Press Release August 18, 2026 1 | 14

Houston, Texas and Tuebingen, Germany, August 18, 2026 – Immatics N.V. (NASDAQ: IMTX, “Immatics” or the “Company”), the global leader in precision targeting of PRAME with multiple clinical-stage programs spanning cell therapies and bispecifics, today provided a business update and reported financial results for the quarter ended June 30, 2026.
“The Phase 3 SUPRAME trial continues to enroll patients on schedule across sites in North America and Europe. In parallel, the data from the Phase 1b anzu-cel study continue to mature. We are now observing that aggregate progression and death events in the SUPRAME trial are occurring more slowly than originally modeled. Based on these results and FDA feedback, we plan to proceed directly to a streamlined final analysis, while maintaining robust statistical power for the primary PFS endpoint,” said Harpreet Singh, Ph.D., Chief Executive Officer and Co-Founder of Immatics. “We believe this approach provides the most efficient path to generating definitive data for regulatory approval and look forward to reporting topline results in the first half of 2027. We continue to build the foundation for the commercial launch to bring anzu-cel to patients who urgently need new treatment options, while advancing the PRAME franchise across our pipeline.”
Second Quarter 2026 and Subsequent Company Progress
PRAME Franchise – Cell Therapy
Anzu-cel (IMA203) PRAME Cell Therapy – First Market Entry in Advanced Melanoma
Anzu-cel (anzutresgene autoleucel), previously called IMA203, is Immatics’ lead PRAME cell therapy and is expected to be the Company’s first PRAME therapy to enter the market in advanced melanoma. The current addressable patient population for anzu-cel’s first target indications, second-line or later (2L) advanced cutaneous melanoma, as well as metastatic uveal melanoma includes ~9,000 patients2.
1 All amounts converted using the exchange rate published by the European Central Bank in effect as of June 30, 2026 (1 EUR = 1.1394 USD).
2 Refers to PRAME+/HLA-A*02:01+ patients per year in the U.S. and EU5 in 2025; Source: Clarivate Disease Landscape and Forecast.
Immatics Press Release August 18, 2026 2 | 14

Phase 3 trial, SUPRAME, for anzu-cel (IMA203) in previously treated, advanced melanoma
Immatics Press Release August 18, 2026 3 | 14

Phase 1/2 trial for anzu-cel (IMA203) in previously treated, metastatic melanoma
Phase 2 cohort for anzu-cel (IMA203) PRAME cell therapy in patients with metastatic uveal melanoma
IMA203CD8 PRAME Cell Therapy – Expansion to All Advanced PRAME Cancers
IMA203CD8 is the Company’s PRAME cell therapy product candidate being developed with the goal of expanding into all advanced PRAME cancers. Given its enhanced pharmacology profile, the Company intends to pursue the clinical development of this product candidate with a tumor-agnostic approach, including gynecologic cancers (ovarian and uterine).
Immatics Press Release August 18, 2026 4 | 14

PRAME Franchise - Bispecifics
IMA402 PRAME Bispecific – Expansion to Earlier-Line PRAME Cancers
To expand the PRAME opportunity to earlier-line PRAME cancers, the Company is developing its off-the-shelf, next-generation, half-life extended TCR bispecific, IMA402, as a monotherapy or in combination with standard of care, with a focus on melanoma and gynecologic cancers. In addition, Immatics is exploring the combination of IMA402 PRAME bispecific with IMA401 MAGEA4/8 bispecific in squamous non-small cell lung cancer (sqNSCLC) and potentially other solid tumor indications.
3 Mair K, et al. N Engl J Med. 2026;395:721-724
Immatics Press Release August 18, 2026 5 | 14

Corporate Development:
Second Quarter 2026 Financial Results
Cash Position: Cash and cash equivalents, as well as other financial assets, total $448.2 million1 (€393.4 million) as of June 30, 2026, compared to $534.7 million1 (€469.3 million) as of December 31, 2025. The decrease is the result of ongoing research and development activities, partially offset by the net proceeds of an at-the-market offering of $24.2 million1 (€21.2 million) as well as changes in net working capital and foreign exchange rate differences.
Revenue: Total revenue, consisting of revenue from collaboration agreements, was $10.4 million1 (€9.1 million) for the three months ended June 30, 2026, compared to $5.4 million1 (€4.7 million) for the three months ended June 30, 2025. The increase is mainly due to a higher level of activity and proportion of costs incurred relative to the overall plan of collaboration activities within the quarter.
Research and Development Expenses: R&D expenses were $71.1 million1 (€62.4 million) for the three months ended June 30, 2026, compared to $51.4 million1 (€45.1 million) for the three months ended June 30, 2025. The increase mainly resulted from costs associated with advancing the product candidates in clinical trials, particularly the SUPRAME trial.
Immatics Press Release August 18, 2026 6 | 14

General and Administrative Expenses: G&A expenses were $15.8 million1 (€13.9 million) for the three months ended June 30, 2026, compared to $14.6 million1 (€12.8 million) for the three months ended June 30, 2025. The increase mainly results from activities in preparation for commercialization.
Net Profit and Loss: Net loss was $71.2 million1 (€62.5 million) for the three months ended June 30, 2026, compared to a net loss of $80.1 million1 (€70.3 million) for the three months ended June 30, 2025. The decrease is mainly driven by unrealized non-cash foreign exchange rate losses during the three months ended June 30, 2025, and to a lesser extent by higher collaboration revenue, partially offset by higher costs associated with the SUPRAME trial in the three months ended June 30, 2026.
Full financial statements can be found in our Report on Form 6-K filed with the Securities and Exchange Commission (SEC) on August 18, 2026, and published on the SEC website under www.sec.gov.
Upcoming Investor Conferences
To see the full list of events and presentations, visit: https://investors.immatics.com/events-presentations.
About PRAME
PRAME is a tumor-associated target expressed in more than 50 cancers. Immatics’ PRAME franchise includes multiple product candidates, therapeutic modalities, indications and combination approaches: anzu-cel (anzutresgene autoleucel; IMA203) and IMA203CD8, both PRAME-directed cell therapies, and IMA402, a PRAME-directed bispecific. Combination approaches include IMA402 with immune checkpoint inhibitors, IMA402 with the MAGEA4/8-directed bispecific IMA401, and anzu-cel in combination with Moderna’s PRAME mRNA therapy designed to enhance the cell therapy response.
About Immatics
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Immatics intends to use its website www.immatics.com as a means of disclosing material non-public information. For regular updates, you can also follow us on LinkedIn and Instagram.
Immatics Press Release August 18, 2026 7 | 14

Forward-Looking Statements
Certain statements in this press release may be considered forward-looking statements. Forward-looking statements generally relate to future events or the Company’s future financial or operating performance. For example, statements concerning timing of data read-outs for product candidates, the timing, outcome and design of clinical trials, the nature of clinical trials (including whether such clinical trials will be registration-enabling), the timing and outcomes of IND, CTA or BLA filings or commercial launches, estimated market opportunities of product candidates, the Company’s focus on partnerships to advance its strategy, and other metrics are forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “may”, “should”, “expect”, “plan”, “target”, “intend”, “will”, “estimate”, “anticipate”, “believe”, “predict”, “potential” or “continue”, or the negatives of these terms or variations of them or similar terminology. Such forward-looking statements are subject to risks, uncertainties, and other factors which could cause actual results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by Immatics and its management, are inherently uncertain. New risks and uncertainties may emerge from time to time, and it is not possible to predict all risks and uncertainties. Factors that may cause actual results to differ materially from current expectations include, but are not limited to, various factors beyond management's control including general economic conditions and other risks, uncertainties and factors set forth in the Company’s Annual Report on Form 20-F and other filings with the Securities and Exchange Commission (SEC). Nothing in this press release should be regarded as a representation by any person that the forward-looking statements set forth herein will be achieved or that any of the contemplated results of such forward-looking statements will be achieved. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. The Company undertakes no duty to update these forward-looking statements. All the scientific and clinical data presented within this press release are – by definition prior to completion of the clinical trial and a clinical study report – preliminary in nature and subject to further quality checks including customary source data verification.
Immatics Press Release August 18, 2026 8 | 14

For more information, please contact:
Media |
|
Trophic Communications |
|
Phone: +49 151 74416179 |
|
immatics@trophic.eu |
|
Immatics N.V. |
|
Jordan Silverstein |
|
Head of Strategy |
|
Phone: +1 346 319-3325 |
|
InvestorRelations@immatics.com |
|
Immatics Press Release August 18, 2026 9 | 14

Immatics N.V. and subsidiaries
Condensed Consolidated Statement of Loss of Immatics N.V.
|
|
Three months ended June 30, |
|
|
|
Six months ended June 30, |
|
||||||||||
|
|
2026 |
|
|
2025 |
|
|
|
2026 |
|
|
2025 |
|
||||
|
|
(Euros in thousands, except per share data) |
|
|
|
(Euros in thousands, except per share data) |
|
||||||||||
Revenue from collaboration agreements |
|
|
9,144 |
|
|
|
4,737 |
|
|
|
|
16,756 |
|
|
|
23,318 |
|
Research and development expenses |
|
|
(62,411 |
) |
|
|
(45,106 |
) |
|
|
|
(121,597 |
) |
|
|
(87,014 |
) |
General and administrative expenses |
|
|
(13,937 |
) |
|
|
(12,780 |
) |
|
|
|
(28,450 |
) |
|
|
(24,847 |
) |
Other income |
|
|
— |
|
|
|
22 |
|
|
|
|
24 |
|
|
|
41 |
|
Operating result |
|
|
(67,204 |
) |
|
|
(53,127 |
) |
|
|
|
(133,267 |
) |
|
|
(88,502 |
) |
Change in fair value of liabilities for warrants |
|
|
— |
|
|
|
133 |
|
|
|
|
— |
|
|
|
1,730 |
|
Other financial income |
|
|
4,802 |
|
|
|
4,421 |
|
|
|
|
13,341 |
|
|
|
10,685 |
|
Other financial expenses |
|
|
(364 |
) |
|
|
(22,776 |
) |
|
|
|
(602 |
) |
|
|
(36,113 |
) |
Financial result |
|
|
4,438 |
|
|
|
(18,222 |
) |
|
|
|
12,739 |
|
|
|
(23,698 |
) |
Loss before taxes |
|
|
(62,766 |
) |
|
|
(71,349 |
) |
|
|
|
(120,528 |
) |
|
|
(112,200 |
) |
Taxes on income |
|
|
274 |
|
|
|
1,001 |
|
|
|
|
222 |
|
|
|
1,996 |
|
Net loss |
|
|
(62,492 |
) |
|
|
(70,348 |
) |
|
|
|
(120,306 |
) |
|
|
(110,204 |
) |
Net loss per share: |
|
|
|
|
|
|
|
|
|
|
|
|
|
||||
Basic |
|
|
(0.46 |
) |
|
|
(0.58 |
) |
|
|
|
(0.89 |
) |
|
|
(0.91 |
) |
Diluted |
|
|
(0.46 |
) |
|
|
(0.58 |
) |
|
|
|
(0.89 |
) |
|
|
(0.91 |
) |
Immatics Press Release August 18, 2026 10 | 14

Immatics N.V. and subsidiaries
Condensed Consolidated Statement of Comprehensive Loss of Immatics N.V.
|
|
Three months ended June 30, |
|
|
|
Six months ended June 30, |
|
||||||||||
|
|
2026 |
|
|
2025 |
|
|
|
2026 |
|
|
2025 |
|
||||
|
|
(Euros in thousands) |
|
|
|
(Euros in thousands) |
|
||||||||||
Net loss |
|
|
(62,492 |
) |
|
|
(70,348 |
) |
|
|
|
(120,306 |
) |
|
|
(110,204 |
) |
Other comprehensive income/(loss) |
|
|
|
|
|
|
|
|
|
|
|
|
|
||||
Items that may be reclassified subsequently to profit or loss |
|
|
|
|
|
|
|
|
|
|
|
|
|
||||
Currency translation differences from foreign operations |
|
|
1,191 |
|
|
|
(5,833 |
) |
|
|
|
3,066 |
|
|
|
(8,544 |
) |
Total comprehensive loss for the period |
|
|
(61,301 |
) |
|
|
(76,181 |
) |
|
|
|
(117,240 |
) |
|
|
(118,748 |
) |
Immatics Press Release August 18, 2026 11 | 14

Immatics N.V. and subsidiaries
Condensed Consolidated Statement of Financial Position of Immatics N.V.
|
|
As of |
|
|||||
|
|
June 30, 2026 |
|
|
December 31, 2025 |
|
||
|
|
(Euros in thousands) |
|
|||||
Assets |
|
|
|
|
|
|
||
Current assets |
|
|
|
|
|
|
||
Cash and cash equivalents |
|
|
232,459 |
|
|
|
345,918 |
|
Other financial assets |
|
|
160,891 |
|
|
|
123,419 |
|
Accounts receivables |
|
|
5,629 |
|
|
|
6,099 |
|
Other current assets |
|
|
30,213 |
|
|
|
28,572 |
|
Total current assets |
|
|
429,192 |
|
|
|
504,008 |
|
Non-current assets |
|
|
|
|
|
|
||
Property, plant and equipment |
|
|
39,981 |
|
|
|
42,111 |
|
Intangible assets |
|
|
1,562 |
|
|
|
1,582 |
|
Right-of-use assets |
|
|
11,717 |
|
|
|
12,786 |
|
Other non-current assets |
|
|
3,283 |
|
|
|
1,850 |
|
Total non-current assets |
|
|
56,543 |
|
|
|
58,329 |
|
Total assets |
|
|
485,735 |
|
|
|
562,337 |
|
Liabilities and shareholders’ equity |
|
|
|
|
|
|
||
Current liabilities |
|
|
|
|
|
|
||
Provisions |
|
|
5,901 |
|
|
|
— |
|
Accounts payables |
|
|
33,155 |
|
|
|
18,832 |
|
Deferred revenue |
|
|
9,567 |
|
|
|
15,816 |
|
Lease liabilities |
|
|
2,666 |
|
|
|
2,757 |
|
Other current liabilities |
|
|
5,664 |
|
|
|
5,607 |
|
Total current liabilities |
|
|
56,953 |
|
|
|
43,012 |
|
Non-current liabilities |
|
|
|
|
|
|
||
Deferred revenue |
|
|
13,632 |
|
|
|
18,541 |
|
Lease liabilities |
|
|
11,940 |
|
|
|
12,878 |
|
Deferred tax liabilities |
|
|
3,585 |
|
|
|
3,807 |
|
Total non-current liabilities |
|
|
29,157 |
|
|
|
35,226 |
|
Shareholders’ equity |
|
|
|
|
|
|
||
Share capital |
|
|
1,367 |
|
|
|
1,341 |
|
Share premium |
|
|
1,310,078 |
|
|
|
1,277,338 |
|
Accumulated deficit |
|
|
(906,294 |
) |
|
|
(785,988 |
) |
Other reserves |
|
|
(5,526 |
) |
|
|
(8,592 |
) |
Total shareholders’ equity |
|
|
399,625 |
|
|
|
484,099 |
|
Total liabilities and shareholders’ equity |
|
|
485,735 |
|
|
|
562,337 |
|
Immatics Press Release August 18, 2026 12 | 14

Immatics N.V. and subsidiaries
Condensed Consolidated Statement of Cash Flows of Immatics N.V.
|
|
Six months ended June 30, |
|
|||||
|
|
2026 |
|
|
2025 |
|
||
|
|
(Euros in thousands) |
|
|||||
Cash flows from operating activities |
|
|
|
|
|
|
||
Net loss |
|
|
(120,306 |
) |
|
|
(110,204 |
) |
Taxes on income |
|
|
(222 |
) |
|
|
(1,996 |
) |
Loss before tax |
|
|
(120,528 |
) |
|
|
(112,200 |
) |
Adjustments for: |
|
|
|
|
|
|
||
Interest income |
|
|
(6,867 |
) |
|
|
(9,719 |
) |
Depreciation and amortization |
|
|
5,777 |
|
|
|
6,166 |
|
Interest expenses |
|
|
415 |
|
|
|
493 |
|
Equity-settled share-based payment |
|
|
10,977 |
|
|
|
8,471 |
|
Net foreign exchange differences and expected credit losses |
|
|
(6,833 |
) |
|
|
34,241 |
|
Change in fair value of liabilities for warrants |
|
|
— |
|
|
|
(1,730 |
) |
Loss from disposal of fixed assets |
|
|
48 |
|
|
|
40 |
|
Changes in: |
|
|
|
|
|
|
||
Decrease in accounts receivables |
|
|
610 |
|
|
|
3,894 |
|
Increase in other assets |
|
|
(1,260 |
) |
|
|
(277 |
) |
Increase/(decrease) in deferred revenue, accounts payables and other liabilities |
|
|
9,876 |
|
|
|
(15,534 |
) |
Interest received |
|
|
7,022 |
|
|
|
18,012 |
|
Interest paid |
|
|
(415 |
) |
|
|
(493 |
) |
Income tax paid |
|
|
(1,326 |
) |
|
|
(5,445 |
) |
Income tax refunded |
|
|
— |
|
|
|
820 |
|
Net cash used in operating activities |
|
|
(102,504 |
) |
|
|
(73,261 |
) |
Cash flows from investing activities |
|
|
|
|
|
|
||
Payments for property, plant and equipment |
|
|
(1,634 |
) |
|
|
(4,503 |
) |
Payments for intangible assets |
|
|
— |
|
|
|
(190 |
) |
Proceeds from disposal of property, plant and equipment |
|
|
27 |
|
|
|
47 |
|
Payments for investments classified in other financial assets |
|
|
(140,165 |
) |
|
|
(280,651 |
) |
Proceeds from maturity of investments classified in other financial assets |
|
|
105,535 |
|
|
|
396,353 |
|
Net cash provided by/(used in) investing activities |
|
|
(36,237 |
) |
|
|
111,056 |
|
Cash flows from financing activities |
|
|
|
|
|
|
||
Proceeds from issuance of shares to equity holders |
|
|
22,330 |
|
|
|
9 |
|
Transaction costs deducted from equity |
|
|
(542 |
) |
|
|
— |
|
Payments of lease liabilities |
|
|
(1,483 |
) |
|
|
(1,473 |
) |
Net cash provided by/(used in) financing activities |
|
|
20,305 |
|
|
|
(1,464 |
) |
Net increase/(decrease) in cash and cash equivalents |
|
|
(118,436 |
) |
|
|
36,331 |
|
Cash and cash equivalents at the beginning of the period |
|
|
345,918 |
|
|
|
236,748 |
|
Effects of exchange rate changes and expected credit losses on cash and cash equivalents |
|
|
4,977 |
|
|
|
(16,444 |
) |
Cash and cash equivalents at the end of the period |
|
|
232,459 |
|
|
|
256,635 |
|
Immatics Press Release August 18, 2026 13 | 14

Immatics N.V. and subsidiaries
Condensed Consolidated Statement of Changes in Shareholders’ Equity of Immatics N.V.
(Euros in thousands) |
|
Share |
|
|
Share |
|
|
Accumulated |
|
|
Other |
|
|
Total |
|
|||||
Balance as of January 1, 2025 |
|
|
1,216 |
|
|
|
1,162,136 |
|
|
|
(589,541 |
) |
|
|
1,031 |
|
|
|
574,842 |
|
Other comprehensive loss |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(8,544 |
) |
|
|
(8,544 |
) |
Net loss |
|
|
— |
|
|
|
— |
|
|
|
(110,204 |
) |
|
|
— |
|
|
|
(110,204 |
) |
Comprehensive loss for the period |
|
|
— |
|
|
|
— |
|
|
|
(110,204 |
) |
|
|
(8,544 |
) |
|
|
(118,748 |
) |
Equity-settled share-based compensation |
|
|
— |
|
|
|
8,471 |
|
|
|
— |
|
|
|
— |
|
|
|
8,471 |
|
Share options exercised |
|
|
— |
|
|
|
9 |
|
|
|
— |
|
|
|
— |
|
|
|
9 |
|
Balance as of June 30, 2025 |
|
|
1,216 |
|
|
|
1,170,616 |
|
|
|
(699,745 |
) |
|
|
(7,513 |
) |
|
|
464,574 |
|
Balance as of January 1, 2026 |
|
|
1,341 |
|
|
|
1,277,338 |
|
|
|
(785,988 |
) |
|
|
(8,592 |
) |
|
|
484,099 |
|
Other comprehensive income |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
3,066 |
|
|
|
3,066 |
|
Net loss |
|
|
— |
|
|
|
— |
|
|
|
(120,306 |
) |
|
|
— |
|
|
|
(120,306 |
) |
Comprehensive income/(loss) for the period |
|
|
— |
|
|
|
— |
|
|
|
(120,306 |
) |
|
|
3,066 |
|
|
|
(117,240 |
) |
Equity-settled share-based compensation |
|
|
— |
|
|
|
10,977 |
|
|
|
— |
|
|
|
— |
|
|
|
10,977 |
|
Share options exercised |
|
|
1 |
|
|
|
636 |
|
|
|
— |
|
|
|
— |
|
|
|
637 |
|
Issue of share capital – net of transaction costs |
|
|
25 |
|
|
|
21,127 |
|
|
|
— |
|
|
|
— |
|
|
|
21,152 |
|
Balance as of June 30, 2026 |
|
|
1,367 |
|
|
|
1,310,078 |
|
|
|
(906,294 |
) |
|
|
(5,526 |
) |
|
|
399,625 |
|
Immatics Press Release August 18, 2026 14 | 14