3.26.1 html 277 366 1 false 90 0 false 10 false false R1.htm 995200090 - Document - Document and Entity Information Sheet http://www.transcodetherapeutics.com/role/DocumentDocumentAndEntityInformation Document and Entity Information Cover 1 false false R2.htm 995200100 - Statement - CONSOLIDATED BALANCE SHEETS Sheet http://www.transcodetherapeutics.com/role/StatementConsolidatedBalanceSheets CONSOLIDATED BALANCE SHEETS Statements 2 false false R3.htm 995200105 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) Sheet http://www.transcodetherapeutics.com/role/StatementConsolidatedBalanceSheetsParenthetical CONSOLIDATED BALANCE SHEETS (Parenthetical) Statements 3 false false R4.htm 995200200 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS Sheet http://www.transcodetherapeutics.com/role/StatementConsolidatedStatementsOfOperations CONSOLIDATED STATEMENTS OF OPERATIONS Statements 4 false false R5.htm 995200300 - Statement - CONSOLIDATED STATEMENTS OF CHANGES IN SERIES A NON-VOTING CONVERTIBLE PREFERRED STOCK, SERIES B NON-VOTING CONVERTIBLE PREFERRED STOCK, AND STOCKHOLDERS' EQUITY (DEFICIT) Sheet http://www.transcodetherapeutics.com/role/StatementConsolidatedStatementsOfChangesInSeriesNonVotingConvertiblePreferredStockSeriesBNonVotingConvertiblePreferredStockAndStockholdersEquityDeficit CONSOLIDATED STATEMENTS OF CHANGES IN SERIES A NON-VOTING CONVERTIBLE PREFERRED STOCK, SERIES B NON-VOTING CONVERTIBLE PREFERRED STOCK, AND STOCKHOLDERS' EQUITY (DEFICIT) Statements 5 false false R6.htm 995200400 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS Sheet http://www.transcodetherapeutics.com/role/StatementConsolidatedStatementsOfCashFlows CONSOLIDATED STATEMENTS OF CASH FLOWS Statements 6 false false R7.htm 995210101 - Disclosure - Nature of Business and Liquidity Sheet http://www.transcodetherapeutics.com/role/DisclosureNatureOfBusinessAndLiquidity Nature of Business and Liquidity Notes 7 false false R8.htm 995210201 - Disclosure - Summary of Significant Accounting Policies Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPolicies Summary of Significant Accounting Policies Notes 8 false false R9.htm 995210301 - Disclosure - Business Combination Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombination Business Combination Notes 9 false false R10.htm 995210401 - Disclosure - Fair Value Measurements Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurements Fair Value Measurements Notes 10 false false R11.htm 995210501 - Disclosure - Prepaid Expenses and Other Current Assets Sheet http://www.transcodetherapeutics.com/role/DisclosurePrepaidExpensesAndOtherCurrentAssets Prepaid Expenses and Other Current Assets Notes 11 false false R12.htm 995210601 - Disclosure - Property and Equipment Sheet http://www.transcodetherapeutics.com/role/DisclosurePropertyAndEquipment Property and Equipment Notes 12 false false R13.htm 995210701 - Disclosure - Receivable from Related Party Sheet http://www.transcodetherapeutics.com/role/DisclosureReceivableFromRelatedParty Receivable from Related Party Notes 13 false false R14.htm 995210801 - Disclosure - Accounts Payable and Accrued Expenses Sheet http://www.transcodetherapeutics.com/role/DisclosureAccountsPayableAndAccruedExpenses Accounts Payable and Accrued Expenses Notes 14 false false R15.htm 995210901 - Disclosure - Convertible Note and SEPA Sheet http://www.transcodetherapeutics.com/role/DisclosureConvertibleNoteAndSepa Convertible Note and SEPA Notes 15 false false R16.htm 995211001 - Disclosure - Grant Income Sheet http://www.transcodetherapeutics.com/role/DisclosureGrantIncome Grant Income Notes 16 false false R17.htm 995211101 - Disclosure - Unleash License Agreement Sheet http://www.transcodetherapeutics.com/role/DisclosureUnleashLicenseAgreement Unleash License Agreement Notes 17 false false R18.htm 995211201 - Disclosure - Commitments and Contingencies Sheet http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingencies Commitments and Contingencies Notes 18 false false R19.htm 995211301 - Disclosure - Contingent Consideration Sheet http://www.transcodetherapeutics.com/role/DisclosureContingentConsideration Contingent Consideration Notes 19 false false R20.htm 995211401 - Disclosure - Stockholders' Equity (Deficit) Sheet http://www.transcodetherapeutics.com/role/DisclosureStockholdersEquityDeficit Stockholders' Equity (Deficit) Notes 20 false false R21.htm 995211501 - Disclosure - Warrants Sheet http://www.transcodetherapeutics.com/role/DisclosureWarrants Warrants Notes 21 false false R22.htm 995211601 - Disclosure - Share-Based Compensation Sheet http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensation Share-Based Compensation Notes 22 false false R23.htm 995211701 - Disclosure - Employee Stock Purchase Plan Sheet http://www.transcodetherapeutics.com/role/DisclosureEmployeeStockPurchasePlan Employee Stock Purchase Plan Notes 23 false false R24.htm 995211801 - Disclosure - Net Loss per Share Sheet http://www.transcodetherapeutics.com/role/DisclosureNetLossPerShare Net Loss per Share Notes 24 false false R25.htm 995211901 - Disclosure - Income Taxes Sheet http://www.transcodetherapeutics.com/role/DisclosureIncomeTaxes Income Taxes Notes 25 false false R26.htm 995212001 - Disclosure - Segment Reporting Sheet http://www.transcodetherapeutics.com/role/DisclosureSegmentReporting Segment Reporting Notes 26 false false R27.htm 995212101 - Disclosure - Subsequent Events Sheet http://www.transcodetherapeutics.com/role/DisclosureSubsequentEvents Subsequent Events Notes 27 false false R28.htm 995410 - Disclosure - Pay vs Performance Disclosure Sheet http://xbrl.sec.gov/ecd/role/PvpDisclosure Pay vs Performance Disclosure Notes 28 false false R29.htm 995445 - Disclosure - Insider Trading Arrangements Sheet http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements Insider Trading Arrangements Notes 29 false false R30.htm 99920202 - Disclosure - Summary of Significant Accounting Policies (Policies) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesPolicies Summary of Significant Accounting Policies (Policies) Policies http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPolicies 30 false false R31.htm 99930203 - Disclosure - Summary of Significant Accounting Policies (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesTables Summary of Significant Accounting Policies (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPolicies 31 false false R32.htm 99930303 - Disclosure - Business Combination (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationTables Business Combination (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureBusinessCombination 32 false false R33.htm 99930403 - Disclosure - Fair Value Measurements (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsTables Fair Value Measurements (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurements 33 false false R34.htm 99930503 - Disclosure - Prepaid Expenses and Other Current Assets (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosurePrepaidExpensesAndOtherCurrentAssetsTables Prepaid Expenses and Other Current Assets (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosurePrepaidExpensesAndOtherCurrentAssets 34 false false R35.htm 99930603 - Disclosure - Property and Equipment (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosurePropertyAndEquipmentTables Property and Equipment (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosurePropertyAndEquipment 35 false false R36.htm 99930803 - Disclosure - Accounts Payable and Accrued Expenses (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureAccountsPayableAndAccruedExpensesTables Accounts Payable and Accrued Expenses (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureAccountsPayableAndAccruedExpenses 36 false false R37.htm 99931103 - Disclosure - Unleash License Agreement (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureUnleashLicenseAgreementTables Unleash License Agreement (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureUnleashLicenseAgreement 37 false false R38.htm 99931203 - Disclosure - Commitments and Contingencies (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingenciesTables Commitments and Contingencies (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingencies 38 false false R39.htm 99931503 - Disclosure - Warrants (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureWarrantsTables Warrants (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureWarrants 39 false false R40.htm 99931603 - Disclosure - Share-Based Compensation (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensationTables Share-Based Compensation (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensation 40 false false R41.htm 99931803 - Disclosure - Net Loss per Share (Tables) Sheet http://www.transcodetherapeutics.com/role/DisclosureNetLossPerShareTables Net Loss per Share (Tables) Tables http://www.transcodetherapeutics.com/role/DisclosureNetLossPerShare 41 false false R42.htm 99940101 - Disclosure - Nature of Business and Liquidity (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureNatureOfBusinessAndLiquidityDetails Nature of Business and Liquidity (Details) Details http://www.transcodetherapeutics.com/role/DisclosureNatureOfBusinessAndLiquidity 42 false false R43.htm 99940201 - Disclosure - Summary of Significant Accounting Policies - Estimated useful life of property and equipment (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesEstimatedUsefulLifeOfPropertyAndEquipmentDetails Summary of Significant Accounting Policies - Estimated useful life of property and equipment (Details) Details 43 false false R44.htm 99940202 - Disclosure - Summary of Significant Accounting Policies - Reverse Stock Splits (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesReverseStockSplitsDetails Summary of Significant Accounting Policies - Reverse Stock Splits (Details) Details 44 false false R45.htm 99940203 - Disclosure - Summary of Significant Accounting Policies - Indefinite-Lived Intangible Assets (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesIndefiniteLivedIntangibleAssetsDetails Summary of Significant Accounting Policies - Indefinite-Lived Intangible Assets (Details) Details 45 false false R46.htm 99940204 - Disclosure - Summary of Significant Accounting Policies - Goodwill (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesGoodwillDetails Summary of Significant Accounting Policies - Goodwill (Details) Details 46 false false R47.htm 99940205 - Disclosure - Summary of Significant Accounting Policies - Contingent Consideration (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSummaryOfSignificantAccountingPoliciesContingentConsiderationDetails Summary of Significant Accounting Policies - Contingent Consideration (Details) Details 47 false false R48.htm 99940301 - Disclosure - Business Combination (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationDetails Business Combination (Details) Details http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationTables 48 false false R49.htm 99940302 - Disclosure - Business Combination - Fair value of the consideration (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationFairValueOfConsiderationDetails Business Combination - Fair value of the consideration (Details) Details 49 false false R50.htm 99940303 - Disclosure - Business Combination - Assets acquired and liabilities assumed (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationAssetsAcquiredAndLiabilitiesAssumedDetails Business Combination - Assets acquired and liabilities assumed (Details) Details 50 false false R51.htm 99940304 - Disclosure - Business Combination - Intangible assets and goodwill acquired (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureBusinessCombinationIntangibleAssetsAndGoodwillAcquiredDetails Business Combination - Intangible assets and goodwill acquired (Details) Details 51 false false R52.htm 99940401 - Disclosure - Fair Value Measurements - Additional Details (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsAdditionalDetailsDetails Fair Value Measurements - Additional Details (Details) Details 52 false false R53.htm 99940402 - Disclosure - Fair Value Measurements - Key assumptions (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsKeyAssumptionsDetails Fair Value Measurements - Key assumptions (Details) Details 53 false false R54.htm 99940403 - Disclosure - Fair Value Measurements - Contingent Consideration (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsContingentConsiderationDetails Fair Value Measurements - Contingent Consideration (Details) Details 54 false false R55.htm 99940404 - Disclosure - Fair Value Measurements - Fair value of contingent consideration (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsFairValueOfContingentConsiderationDetails Fair Value Measurements - Fair value of contingent consideration (Details) Details 55 false false R56.htm 99940405 - Disclosure - Fair Value Measurements - Warrant liability fair value (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsWarrantLiabilityFairValueDetails Fair Value Measurements - Warrant liability fair value (Details) Details 56 false false R57.htm 99940406 - Disclosure - Fair Value Measurements - Changes in the Fair Value of Level 3 Financial Instruments (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureFairValueMeasurementsChangesInFairValueOfLevel3FinancialInstrumentsDetails Fair Value Measurements - Changes in the Fair Value of Level 3 Financial Instruments (Details) Details 57 false false R58.htm 99940501 - Disclosure - Prepaid Expenses and Other Current Assets (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosurePrepaidExpensesAndOtherCurrentAssetsDetails Prepaid Expenses and Other Current Assets (Details) Details http://www.transcodetherapeutics.com/role/DisclosurePrepaidExpensesAndOtherCurrentAssetsTables 58 false false R59.htm 99940601 - Disclosure - Property and Equipment (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosurePropertyAndEquipmentDetails Property and Equipment (Details) Details http://www.transcodetherapeutics.com/role/DisclosurePropertyAndEquipmentTables 59 false false R60.htm 99940701 - Disclosure - Receivable from Related Party (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureReceivableFromRelatedPartyDetails Receivable from Related Party (Details) Details http://www.transcodetherapeutics.com/role/DisclosureReceivableFromRelatedParty 60 false false R61.htm 99940801 - Disclosure - Accounts Payable and Accrued Expenses (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureAccountsPayableAndAccruedExpensesDetails Accounts Payable and Accrued Expenses (Details) Details http://www.transcodetherapeutics.com/role/DisclosureAccountsPayableAndAccruedExpensesTables 61 false false R62.htm 99940901 - Schedule - Convertible Note and SEPA (Details) Sheet http://www.transcodetherapeutics.com/role/ScheduleConvertibleNoteAndSepaDetails Convertible Note and SEPA (Details) Details http://www.transcodetherapeutics.com/role/DisclosureConvertibleNoteAndSepa 62 false false R63.htm 99941001 - Disclosure - Grant Income (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureGrantIncomeDetails Grant Income (Details) Details http://www.transcodetherapeutics.com/role/DisclosureGrantIncome 63 false false R64.htm 99941101 - Disclosure - Unleash License Agreement (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureUnleashLicenseAgreementDetails Unleash License Agreement (Details) Details http://www.transcodetherapeutics.com/role/DisclosureUnleashLicenseAgreementTables 64 false false R65.htm 99941201 - Disclosure - Commitments and Contingencies - Leases (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingenciesLeasesDetails Commitments and Contingencies - Leases (Details) Details 65 false false R66.htm 99941202 - Disclosure - Commitments and Contingencies - License Agreement (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingenciesLicenseAgreementDetails Commitments and Contingencies - License Agreement (Details) Details 66 false false R67.htm 99941203 - Disclosure - Commitments and Contingencies - Collaboration Agreement and Litigation (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureCommitmentsAndContingenciesCollaborationAgreementAndLitigationDetails Commitments and Contingencies - Collaboration Agreement and Litigation (Details) Details 67 false false R68.htm 99941301 - Disclosure - Contingent Consideration (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureContingentConsiderationDetails Contingent Consideration (Details) Details http://www.transcodetherapeutics.com/role/DisclosureContingentConsideration 68 false false R69.htm 99941401 - Disclosure - Stockholders' Equity (Deficit) (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureStockholdersEquityDeficitDetails Stockholders' Equity (Deficit) (Details) Details http://www.transcodetherapeutics.com/role/DisclosureStockholdersEquityDeficit 69 false false R70.htm 99941501 - Disclosure - Warrants (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureWarrantsDetails Warrants (Details) Details http://www.transcodetherapeutics.com/role/DisclosureWarrantsTables 70 false false R71.htm 99941502 - Disclosure - Warrants - Summary of Company's Outstanding or Issuable Warrants (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureWarrantsSummaryOfCompanySOutstandingOrIssuableWarrantsDetails Warrants - Summary of Company's Outstanding or Issuable Warrants (Details) Details 71 false false R72.htm 99941601 - Disclosure - Share-Based Compensation - Information about Plans (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensationInformationAboutPlansDetails Share-Based Compensation - Information about Plans (Details) Details 72 false false R73.htm 99941602 - Disclosure - Share-Based Compensation - Information About Options to Purchase Common Stock (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensationInformationAboutOptionsToPurchaseCommonStockDetails Share-Based Compensation - Information About Options to Purchase Common Stock (Details) Details 73 false false R74.htm 99941603 - Disclosure - Share-Based Compensation - Stock-based Compensation Expense (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureShareBasedCompensationStockBasedCompensationExpenseDetails Share-Based Compensation - Stock-based Compensation Expense (Details) Details 74 false false R75.htm 99941701 - Disclosure - Employee Stock Purchase Plan (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureEmployeeStockPurchasePlanDetails Employee Stock Purchase Plan (Details) Details http://www.transcodetherapeutics.com/role/DisclosureEmployeeStockPurchasePlan 75 false false R76.htm 99941801 - Disclosure - Net Loss per Share - Computation of basic and diluted net loss per share (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureNetLossPerShareComputationOfBasicAndDilutedNetLossPerShareDetails Net Loss per Share - Computation of basic and diluted net loss per share (Details) Details 76 false false R77.htm 99941901 - Disclosure - Income Taxes (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureIncomeTaxesDetails Income Taxes (Details) Details http://www.transcodetherapeutics.com/role/DisclosureIncomeTaxes 77 false false R78.htm 99942001 - Disclosure - Segment Reporting (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSegmentReportingDetails Segment Reporting (Details) Details http://www.transcodetherapeutics.com/role/DisclosureSegmentReporting 78 false false R79.htm 99942101 - Disclosure - Subsequent Events (Details) Sheet http://www.transcodetherapeutics.com/role/DisclosureSubsequentEventsDetails Subsequent Events (Details) Details http://www.transcodetherapeutics.com/role/DisclosureSubsequentEvents 79 false false All Reports Book All Reports rnaz-20260630.xsd rnaz-20260630_cal.xml rnaz-20260630_def.xml rnaz-20260630_lab.xml rnaz-20260630_pre.xml rnaz-20260630x10q.htm http://fasb.org/us-gaap/2025 http://xbrl.sec.gov/dei/2025 http://xbrl.sec.gov/ecd/2025 true true