The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIVAX SA SPONSORED ADS 00370M103 80,622,300 605,000 SH SOLE 605,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 3,120,000 1,500,000 SH SOLE 1,500,000 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 14,368,000 800,000 SH SOLE 800,000 0 0
AN2 THERAPEUTICS INC COM 037326105 3,625,329 749,035 SH SOLE 749,035 0 0
APOGEE THERAPEUTICS INC COM 03770N101 9,291,100 70,000 SH SOLE 70,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306 6,930,000 375,000 SH SOLE 375,000 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309 33,595,356 1,395,156 SH SOLE 1,395,156 0 0
CELCUITY INC COM 15102K100 43,577,368 416,530 SH SOLE 416,530 0 0
CLENE INC COM NEW 185634201 2,939,105 477,515 SH SOLE 477,515 0 0
COGENT BIOSCIENCES INC COM 19240Q201 8,707,500 225,000 SH SOLE 225,000 0 0
CONTINEUM THERAPEUTICS INC CL A 21217B100 8,096,660 494,000 SH SOLE 494,000 0 0
CORCEPT THERAPEUTICS INC COM 218352102 29,171,725 335,500 SH SOLE 335,500 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 16,434,000 1,100,000 SH SOLE 1,100,000 0 0
CRESCENT BIOPHARMA INC. COM 38000Q201 8,166,348 453,686 SH SOLE 453,686 0 0
CYBIN INC COM NEW 23256X407 5,221,900 790,000 SH SOLE 790,000 0 0
CYTOKINETICS INC COM NEW 23282W605 8,519,000 100,000 SH SOLE 100,000 0 0
DEFINIUM THERAPEUTICS INC COM SHS 24477V105 46,969,440 998,500 SH SOLE 998,500 0 0
EDESA BIOTECH INC COM NEW 27966L306 1,666,650 205,000 SH SOLE 205,000 0 0
FAETH THERAPEUTICS inc COM NEW 81728A207 4,512,625 180,505 SH SOLE 180,505 0 0
FORTE BIOSCIENCES INC COM NEW 34962G208 5,833,125 274,500 SH SOLE 274,500 0 0
IMMATICS N.V SHS N44445109 4,811,750 475,000 SH SOLE 475,000 0 0
INOVIO PHARMACEUTICALS INC COM SHS 45773H409 3,129,493 2,844,994 SH SOLE 2,844,994 0 0
INVIVYD INC COM 00534A102 1,308,600 1,500,000 SH SOLE 1,500,000 0 0
KARYOPHARM THERAPEUTICS INC COM NEW 48576U205 2,955,777 302,536 SH SOLE 302,536 0 0
KAZIA THERAPEUTICS LTD SPONSORED ADS 48669G303 7,884,800 560,000 SH SOLE 560,000 0 0
KODIAK SCIENCES INC COM 50015M109 57,567,296 1,477,600 SH SOLE 1,477,600 0 0
KYMERA THERAPEUTICS INC COM 501575104 49,204,897 429,100 SH SOLE 429,100 0 0
LB PHARMACEUTICALS INC COM SHS 50180M108 2,271,850 70,000 SH SOLE 70,000 0 0
MAPLIGHT THERAPEUTICS INC COM 56565P103 2,688,000 75,000 SH SOLE 75,000 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 893,332 666,666 SH SOLE 666,666 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104 5,354,250 275,000 SH SOLE 275,000 0 0
NEUMORA THERAPEUTICS INC. COM 640979100 3,400,000 2,000,000 SH SOLE 2,000,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 2,426,000 100,000 SH SOLE 100,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 12,766,000 1,300,000 SH SOLE 1,300,000 0 0
ODYSSEY THERAPEUTICS INC COMMON STOCK 67613T104 5,145,250 275,000 SH SOLE 275,000 0 0
OPUS GENETICS INC COM 67577R102 11,569,650 2,815,000 SH SOLE 2,815,000 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 3,790,500 350,000 SH SOLE 350,000 0 0
PALISADE BIO INC COM 696389402 10,031,739 4,799,875 SH SOLE 4,799,875 0 0
PEPGEN INC COM 713317105 491,206 272,892 SH SOLE 272,892 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207 15,553,339 46,457 SH SOLE 46,457 0 0
PRECIGEN INC COM 74017N105 29,355,000 5,150,000 SH SOLE 5,150,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 20,838,600 170,000 SH SOLE 170,000 0 0
PTC THERAPEUTICS INC COM 69366J200 16,314,000 200,000 SH SOLE 200,000 0 0
Q32 BIO INC COM 746964105 40,122,209 3,149,310 SH SOLE 3,149,310 0 0
REGENXBIO INC COM 75901B107 179,700 15,000 SH SOLE 15,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 8,419,500 450,000 SH SOLE 450,000 0 0
RELMADA THERAPEUTICS INC COM 75955J402 5,827,374 842,106 SH SOLE 842,106 0 0
REPLIMUNE GROUP INC COM 76029N106 44,091,810 3,983,000 SH SOLE 3,983,000 0 0
REVOLUTION MEDICINES INC COM 76155X100 93,640,000 500,000 SH SOLE 500,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 2,695,500 150,000 SH SOLE 150,000 0 0
SHATTUCK LABS INC COM 82024L103 6,940,000 1,000,000 SH SOLE 1,000,000 0 0
SOLID BIOSCIENCES INC COM NEW 83422E204 2,997,000 300,000 SH SOLE 300,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202 8,878,000 100,000 SH SOLE 100,000 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 4,025,250 75,000 SH SOLE 75,000 0 0
Surrozen Inc. COM NEW 86889P208 26,963,591 1,105,683 SH SOLE 1,105,683 0 0
SURROZEN INC *W EXP 08/01/203 86889P117 1,067 66,666 SH SOLE 66,666 0 0
TANGO THERAPEUTICS INC COM 87583X109 339,990,606 10,876,219 SH SOLE 10,876,219 0 0
UNIQURE NV SHS N90064101 69,241,998 1,503,300 SH SOLE 1,503,300 0 0
UPSTREAM BIO INC COM 91678A107 1,038,000 150,000 SH SOLE 150,000 0 0
UROGEN PHARMA LTD COM M96088105 18,400,000 500,000 SH SOLE 500,000 0 0
VAXCYTE INC COM 92243G108 18,892,250 325,000 SH SOLE 325,000 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 19,014,540 1,866,000 SH SOLE 1,866,000 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101 5,310,000 900,000 SH SOLE 900,000 0 0