The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIVAX SA SPONSORED ADS 00370M103 16,257,720 122,000 SH OTR 122,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 124,640,224 4,220,800 SH OTR 4,220,800 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 219,594,714 5,917,400 SH OTR 5,917,400 0 0
ALAMAR BIOSCIENCES INC COMMON STOCK 010911105 12,539,961 462,900 SH OTR 462,900 0 0
ALEANNA INC *W EXP 12/13/202 01444V111 297,000 990,000 SH OTR 990,000 0 0
ALEANNA INC COM CL A 01444V103 227,360 78,400 SH OTR 78,400 0 0
ALVOTECH ORDINARY SHARES L01800108 10,552,201 2,859,675 SH OTR 2,859,675 0 0
AMAZON COM INC COM 023135106 627,547,790 2,632,994 SH OTR 2,632,994 0 0
AON PLC SHS CL A G0403H108 458,581,990 1,382,562 SH OTR 1,382,562 0 0
ARAMARK COM 03852U106 206,304,094 3,625,731 SH OTR 3,625,731 0 0
ASSEMBLY BIOSCIENCES INC COM NEW 045396207 44,094,133 1,604,590 SH OTR 1,604,590 0 0
ASTRAZENECA PLC ORD G0593M107 108,841,880 574,000 SH OTR 574,000 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306 46,163,040 2,498,000 SH OTR 2,498,000 0 0
AXALTA COATING SYS LTD COM G0750C108 16,357,160 478,000 SH OTR 478,000 0 0
BAIDU INC SPON ADR REP A 056752108 137,580,588 1,203,785 SH OTR 1,203,785 0 0
BEAM THERAPEUTICS INC COM 07373V105 351,313,111 10,236,396 SH OTR 10,236,396 0 0
BETA BIONICS INC COM 08659B102 9,323,650 595,000 SH OTR 595,000 0 0
BEYOND MEAT INC COM 08862E109 14,250 19,000 SH OTR 19,000 0 0
BIOGEN INC COM 09062X103 15,340,260 71,000 SH OTR 71,000 0 0
BLUE GOLD LTD *W EXP 04/01/203 G1331C112 30,696 255,800 SH OTR 255,800 0 0
BOSTON SCIENTIFIC CORP COM 101137107 449,044,133 10,521,184 SH OTR 10,521,184 0 0
BRIDGEBIO PHARMA INC COM 10806X102 800,143,332 10,743,063 SH OTR 10,743,063 0 0
BRIGHTSPRING HEALTH SVCS INC COM 10950A106 120,845,472 1,732,800 SH OTR 1,732,800 0 0
BROADCOM INC COM 11135F101 435,092,450 1,151,800 SH OTR 1,151,800 0 0
BRUNSWICK CORP COM 117043109 5,138,640 61,000 SH OTR 61,000 0 0
CANOPY GROWTH CORPORATION COM NEW 138035704 17,100 18,000 SH OTR 18,000 0 0
CG ONCOLOGY INC COM 156944100 28,420,000 400,000 SH Call OTR 400,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201 657,900 17,000 SH OTR 17,000 0 0
COMMERCIAL METALS CO COM 201723103 4,204,250 67,000 SH OTR 67,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 336,372,047 8,989,098 SH OTR 8,989,098 0 0
ELECTRONIC ARTS INC COM 285512109 1,623,814,280 7,919,500 SH OTR 7,919,500 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 35,257,385 2,418,202 SH OTR 2,418,202 0 0
EXELIXIS INC COM 30161Q104 732,794,424 13,468,010 SH OTR 13,468,010 0 0
GENTEX CORP COM 371901109 5,028,730 199,000 SH OTR 199,000 0 0
GERON CORP COM 374163103 18,432 14,400 SH OTR 14,400 0 0
GRAIL INC COM 384747101 284,111,340 4,161,584 SH OTR 4,161,584 0 0
GUARDANT HEALTH INC COM 40131M109 48,339,666 322,200 SH OTR 322,200 0 0
IDEXX LABS INC COM 45168D104 4,737,960 9,000 SH OTR 9,000 0 0
IMMUNOVANT INC COM 45258J102 223,666,650 5,805,000 SH OTR 5,805,000 0 0
INFLARX NV COM N44821101 7,448,000 3,325,000 SH OTR 3,325,000 0 0
ISHARES TR ISHARES SEMICDTR 464287523 83,298,800 130,000 SH Put OTR 130,000 0 0
JATT II ACQUISITION CORP ORD SHS G50765109 3,408,000 300,000 SH OTR 300,000 0 0
JOHNSON & JOHNSON COM 478160104 103,619,760 408,000 SH OTR 408,000 0 0
JOYY INC ADS REPSTG COM A 46591M109 46,140,208 699,200 SH OTR 699,200 0 0
KAILERA THERAPEUTICS INC COMMON STOCK 482931102 24,233,000 1,100,000 SH OTR 1,100,000 0 0
KKR & CO INC COM 48251W104 377,977,574 4,118,300 SH OTR 4,118,300 0 0
LANTHEUS HLDGS INC COM 516544103 619,431,160 5,583,479 SH OTR 5,583,479 0 0
LIQUIDIA CORPORATION COM NEW 53635D202 666,944,480 8,365,038 SH OTR 8,365,038 0 0
MAZE THERAPEUTICS INC COM 578784100 33,057,170 1,107,814 SH OTR 1,107,814 0 0
MERCK & CO INC COM 58933Y105 25,571,500 199,000 SH OTR 199,000 0 0
MICROSOFT CORP COM 594918104 415,120,156 1,112,863 SH OTR 1,112,863 0 0
MINERVA NEUROSCIENCES INC COM NEW 603380205 13,125,750 2,365,000 SH OTR 2,365,000 0 0
MOBIA MED INC COMMON STOCK 60705V103 15,122,664 1,128,557 SH OTR 1,128,557 0 0
NATERA INC COM 632307104 602,175,451 2,218,366 SH OTR 2,218,366 0 0
NETEASE COM INC SPONSORED ADS 64110W102 15,825,290 123,500 SH OTR 123,500 0 0
NOVARTIS AG SPONSORED ADR 66987V109 56,889,360 363,000 SH OTR 363,000 0 0
NOVO-NORDISK A S ADR 670100205 125,554,860 2,619,000 SH OTR 2,619,000 0 0
NVNI GROUP LIMITED *W EXP 11/01/202 G50716110 17,550 375,000 SH OTR 375,000 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108 23,856 14,200 SH OTR 14,200 0 0
PARABILIS MEDICINES INC COM 698955101 64,817,634 2,368,200 SH OTR 2,368,200 0 0
PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS G70077105 24,480,000 2,250,000 SH OTR 2,250,000 0 0
PRIME MEDICINE INC COM 74168J101 4,578,711 1,240,843 SH OTR 1,240,843 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 778,248,897 6,348,906 SH OTR 6,348,906 0 0
RANI THERAPEUTICS HLDGS INC COM CL A 753018100 15,740 20,700 SH OTR 20,700 0 0
REVOLUTION MEDICINES INC *W EXP 12/17/202 76155X118 1,128,799 120,085 SH OTR 120,085 0 0
REVOLUTION MEDICINES INC COM 76155X100 2,537,793,075 13,550,796 SH OTR 13,550,796 0 0
RIO TINTO PLC SPONSORED ADR 767204100 17,417,282 183,475 SH OTR 183,475 0 0
ROIVANT SCIENCES LTD SHS G76279101 506,395,510 14,309,000 SH OTR 14,309,000 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104 3,207,950 415,000 SH OTR 415,000 0 0
SCOTTS MIRACLE-GRO CO CL A 810186106 5,993,680 88,000 SH OTR 88,000 0 0
SOLID POWER INC *W EXP 12/08/202 83422N113 41,423 405,316 SH OTR 405,316 0 0
STATE STR SPDR S&P 500 ETF T TR UNIT 78462F103 4,480,620,000 6,000,000 SH Put OTR 6,000,000 0 0
STRATEGY INC NOTE 3/0 594972AU5 2,318,158 2,632,000 PRN OTR 2,632,000 0 0
STRATEGY INC NOTE 12/0 594972AS0 75,366,666 87,858,000 PRN OTR 87,858,000 0 0
STRATEGY INC NOTE 2.250% 6/1 594972AN1 14,189,967 15,000,000 PRN OTR 15,000,000 0 0
SUMMIT MIDSTREAM CORPORATION COM 86614G101 1,657,935 58,214 SH OTR 58,214 0 0
SYNOPSYS INC COM 871607107 370,059,672 829,600 SH OTR 829,600 0 0
TANGO THERAPEUTICS INC COM 87583X109 383,779,020 12,277,000 SH OTR 12,277,000 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106 15,322,500 2,250,000 SH OTR 2,250,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209 1,355,200 40,000 SH OTR 40,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 526,019,392 1,049,185 SH OTR 1,049,185 0 0
TWIST BIOSCIENCE CORP COM 90184D100 219,792,832 2,136,400 SH OTR 2,136,400 0 0
UNITEDHEALTH GROUP INC COM 91324P102 528,071,215 1,270,532 SH OTR 1,270,532 0 0
VNET GROUP INC NOTE 2.000%10/0 90138AAE3 46,808,834 45,000,000 PRN OTR 45,000,000 0 0
VNET GROUP INC SPONSORED ADS A 90138A103 16,015,680 1,992,000 SH OTR 1,992,000 0 0
WABTEC COM 929740108 241,158,009 894,503 SH OTR 894,503 0 0
WARBY PARKER INC CL A COM 93403J106 25,121,520 828,000 SH OTR 828,000 0 0
WAYSTAR HLDG CORP COM 946784105 5,438,397 264,900 SH OTR 264,900 0 0
WELLTOWER INC COM 95040Q104 226,970 1,000 SH OTR 1,000 0 0