000 - Document - Document And Entity Information link:calculationLink link:definitionLink link:presentationLink 001 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) link:calculationLink link:definitionLink link:presentationLink 002 - Statement - Condensed Consolidated Balance Sheets (Current Period Unaudited) (Parentheticals) link:calculationLink link:definitionLink link:presentationLink 003 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) link:calculationLink link:definitionLink link:presentationLink 004 - Statement - Condensed Consolidated Statements of Stockholders' Deficit (Unaudited) link:calculationLink link:definitionLink link:presentationLink 005 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited) link:calculationLink link:definitionLink link:presentationLink 006 - Disclosure - Note 1 - Nature of the Business link:calculationLink link:definitionLink link:presentationLink 007 - Disclosure - Note 2 - Summary of Significant Accounting Policies link:calculationLink link:definitionLink link:presentationLink 008 - Disclosure - Note 3 - Cash and Cash Equivalents link:calculationLink link:definitionLink link:presentationLink 009 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets link:calculationLink link:definitionLink link:presentationLink 010 - Disclosure - Note 5 - Property and Equipment, Net link:calculationLink link:definitionLink link:presentationLink 011 - Disclosure - Note 6 - Accrued Liabilities link:calculationLink link:definitionLink link:presentationLink 012 - Disclosure - Note 7 - Leases link:calculationLink link:definitionLink link:presentationLink 013 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable link:calculationLink link:definitionLink link:presentationLink 014 - Disclosure - Note 9 - Commitments and Contingencies link:calculationLink link:definitionLink link:presentationLink 015 - Disclosure - Note 10 - Income Taxes link:calculationLink link:definitionLink link:presentationLink 016 - Disclosure - Note 11 - Benefit Plans link:calculationLink link:definitionLink link:presentationLink 017 - Disclosure - Note 12 - Fair Value link:calculationLink link:definitionLink link:presentationLink 018 - Disclosure - Note 13 - Capital Stock link:calculationLink link:definitionLink link:presentationLink 019 - Disclosure - Note 14 - Net Loss Per Share link:calculationLink link:definitionLink link:presentationLink 020 - Disclosure - Note 15 - Related Party Transactions link:calculationLink link:definitionLink link:presentationLink 021 - Disclosure - Note 16 - Geographic and Segment Information link:calculationLink link:definitionLink link:presentationLink 995468 - Disclosure - Significant Accounting Policies (Policies) link:calculationLink link:definitionLink link:presentationLink 995469 - Disclosure - Note 3 - Cash and Cash Equivalents (Tables) link:calculationLink link:definitionLink link:presentationLink 995470 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets (Tables) link:calculationLink link:definitionLink link:presentationLink 995471 - Disclosure - Note 5 - Property and Equipment, Net (Tables) link:calculationLink link:definitionLink link:presentationLink 995472 - Disclosure - Note 6 - Accrued Liabilities (Tables) link:calculationLink link:definitionLink link:presentationLink 995473 - Disclosure - Note 7 - Leases (Tables) link:calculationLink link:definitionLink link:presentationLink 995474 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable (Tables) link:calculationLink link:definitionLink link:presentationLink 995475 - Disclosure - Note 10 - Income Taxes (Tables) link:calculationLink link:definitionLink link:presentationLink 995476 - Disclosure - Note 11 - Benefit Plans (Tables) link:calculationLink link:definitionLink link:presentationLink 995477 - Disclosure - Note 12 - Fair Value (Tables) link:calculationLink link:definitionLink link:presentationLink 995478 - Disclosure - Note 13 - Capital Stock (Tables) link:calculationLink link:definitionLink link:presentationLink 995479 - Disclosure - Note 14 - Net Loss Per Share (Tables) link:calculationLink link:definitionLink link:presentationLink 995480 - Disclosure - Note 15 - Related Party Transactions (Tables) link:calculationLink link:definitionLink link:presentationLink 995481 - Disclosure - Note 16 - Geographic and Segment Information (Tables) link:calculationLink link:definitionLink link:presentationLink 995482 - Disclosure - Note 1 - Nature of the Business (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995483 - Disclosure - Note 2 - Summary of Significant Accounting Policies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995484 - Disclosure - Note 3 - Cash and Cash Equivalents - Available-for-sale Securities (Details) link:calculationLink link:definitionLink link:presentationLink 995485 - Disclosure - Note 4 - Prepaid Expenses and Other Current Assets - Schedule of Prepaid Expenses and Other Current Assets (Details) link:calculationLink link:definitionLink link:presentationLink 995486 - Disclosure - Note 5 - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details) link:calculationLink link:definitionLink link:presentationLink 995487 - Disclosure - Note 5 - Property and Equipment, Net - Schedule of Depreciation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995488 - Disclosure - Note 6 - Accrued Liabilities - Schedule of Accrued Liabilities (Details) link:calculationLink link:definitionLink link:presentationLink 995489 - Disclosure - Note 7 - Leases (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995490 - Disclosure - Note 7 - Leases - Maturity Analysis of Leases (Details) link:calculationLink link:definitionLink link:presentationLink 995491 - Disclosure - Note 7 - Leases - Components of Lease Cost (Details) link:calculationLink link:definitionLink link:presentationLink 995492 - Disclosure - Note 7 - Leases - Supplemental Cash Flow Information (Details) link:calculationLink link:definitionLink link:presentationLink 995493 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995494 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Long-term Debt (Details) link:calculationLink link:definitionLink link:presentationLink 995495 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Interest Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995496 - Disclosure - Note 8 - Notes Payable and Convertible Notes Payable - Schedule of Future Payments (Details) link:calculationLink link:definitionLink link:presentationLink 995497 - Disclosure - Note 9 - Commitments and Contingencies (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995498 - Disclosure - Note 10 - Income Taxes - Components of Income (Loss) Before Income Taxes (Details) link:calculationLink link:definitionLink link:presentationLink 995499 - Disclosure - Note 11 - Benefit Plans (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995500 - Disclosure - Note 11 - Benefit Plans - Stock-based Compensation Expense (Details) link:calculationLink link:definitionLink link:presentationLink 995501 - Disclosure - Note 11 - Benefit Plans - Activity Related to Outstanding Stock Options (Details) link:calculationLink link:definitionLink link:presentationLink 995502 - Disclosure - Note 11 - Benefit Plans - Assumptions of Stock Options (Details) link:calculationLink link:definitionLink link:presentationLink 995503 - Disclosure - Note 12 - Fair Value (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995504 - Disclosure - Note 12 - Fair Value - Assets and Liabilities Measured on a Recurring Basis (Details) link:calculationLink link:definitionLink link:presentationLink 995505 - Disclosure - Note 12 - Fair Value - Unobservable Inputs (Details) link:calculationLink link:definitionLink link:presentationLink 995506 - Disclosure - Note 13 - Capital Stock (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995507 - Disclosure - Note 13 - Capital Stock - Outstanding Warrants (Details) link:calculationLink link:definitionLink link:presentationLink 995508 - Disclosure - Note 14 - Net Loss Per Share - Computation of Basic and Diluted Net Income (Loss) Per Share (Details) link:calculationLink link:definitionLink link:presentationLink 995509 - Disclosure - Note 14 - Net Loss Per Share - Antidilutive Securities Excluded from Computation (Details) link:calculationLink link:definitionLink link:presentationLink 995510 - Disclosure - Note 15 - Related Party Transactions (Details Textual) link:calculationLink link:definitionLink link:presentationLink 995511 - Disclosure - Note 15 - Related Party Transactions - Revenue From 4Life Agreement (Details) link:calculationLink link:definitionLink link:presentationLink 995512 - Disclosure - Note 16 - Geographic and Segment Information - Profit and Loss Information by Reportable Segment (Details) link:calculationLink link:definitionLink link:presentationLink 995513 - Disclosure - Note 16 - Geographic and Segment Information - Reconciliation of the Reportable Segments' Loss From Operations to Consolidated (Details) link:calculationLink link:definitionLink link:presentationLink 995514 - Disclosure - Note 16 - Geographic and Segment Information - Assets by Reportable Segment (Details) link:calculationLink link:definitionLink link:presentationLink