| Segment Reporting [Text Block] |
Note 16. Geographic and Segment Information
Geographic Information
All our long-lived assets, composed of property and equipment, net by location, were held in the U.S. All our revenue from external customers was generated in the U.S.
Segment Information
Our Products segment measures of profit and loss is consolidated loss from operations, and its measure of total assets is consolidated total assets. Our CODM uses loss from operations predominantly in the annual budget and forecasting process to monitor variances in budget versus actual results along with consolidated total assets to determine resource allocation. Segment revenue from external customers, significant segment non-cash items, and other significant segment expense categories included within the measure of profit and loss and provided to our CODM were all based on their consolidated amounts. During the three and six months ended June 30, 2026 and 2025, these items were as follows:
| | | Three Months Ended June 30, | | | Six Months Ended June 30, | |
| (in thousands) | | 2026 | | | 2025 | | | 2026 | | | 2025 | |
| Segment revenue from external customers | | $ | 90 | | | $ | 27 | | | $ | 105 | | | $ | 108 | |
| Segment operating expenses: | | | | | | | | | | | | | | | | |
| Cost of revenue | | | 36 | | | | — | | | | 36 | | | | 20 | |
| Research and development: | | | | | | | | | | | | | | | | |
| CNM-Au8: | | | | | | | | | | | | | | | | |
| Amyotrophic lateral sclerosis | | | 712 | | | | 1,468 | | | | 1,536 | | | | 2,811 | |
| Multiple sclerosis | | | 37 | | | | 164 | | | | 107 | | | | 189 | |
| Regulatory activities | | | 371 | | | | 130 | | | | 567 | | | | 260 | |
| General/preclinical/nonclinical | | | 101 | | | | 19 | | | | 121 | | | | 82 | |
| Facilities | | | 393 | | | | 386 | | | | 784 | | | | 805 | |
| Depreciation | | | 336 | | | | 337 | | | | 674 | | | | 675 | |
| Manufacturing | | | 522 | | | | 187 | | | | 155 | | | | 270 | |
| Research | | | 1 | | | | 2 | | | | 10 | | | | 7 | |
| Equipment | | | 24 | | | | 14 | | | | 84 | | | | 28 | |
| Maintenance | | | 32 | | | | 32 | | | | 49 | | | | 64 | |
| Information technology | | | 76 | | | | 54 | | | | 143 | | | | 119 | |
| Personnel | | | 2,188 | | | | 2,100 | | | | 4,211 | | | | 4,260 | |
| Stock-based compensation | | | 526 | | | | 600 | | | | 1,240 | | | | 1,546 | |
| Grant revenue as a reduction of research and development expense | | | (1,864 | ) | | | (2,058 | ) | | | (5,914 | ) | | | (6,225 | ) |
| Other segment items ‒ Research and development(1) | | | 16 | | | | 79 | | | | 33 | | | | 104 | |
| General and administrative: | | | | | | | | | | | | | | | | |
| Insurance | | | 177 | | | | 181 | | | | 328 | | | | 362 | |
| Legal | | | 144 | | | | 175 | | | | 195 | | | | 323 | |
| Finance and accounting | | | 155 | | | | 220 | | | | 488 | | | | 530 | |
| Public and investor relations | | | 109 | | | | 119 | | | | 202 | | | | 230 | |
| Facilities | | | 30 | | | | 31 | | | | 63 | | | | 61 | |
| Depreciation | | | 17 | | | | 29 | | | | 34 | | | | 95 | |
| Information technology | | | 40 | | | | 47 | | | | 62 | | | | 96 | |
| Personnel | | | 779 | | | | 788 | | | | 1,417 | | | | 1,620 | |
| Stock-based compensation | | | 514 | | | | 767 | | | | 1,112 | | | | 1,768 | |
| Grant revenue as a reduction of general and administrative expense | | | (93 | ) | | | (65 | ) | | | (329 | ) | | | (228 | ) |
| Other segment items ‒ General and administrative(2) | | | 58 | | | | 85 | | | | 105 | | | | 176 | |
| Segment loss from operations | | | (5,347 | ) | | | (5,864 | ) | | | (7,408 | ) | | | (9,940 | ) |
| | | | | | | | | | | | | | | | | |
| Reconciliation of segment loss from operations: | | | | | | | | | | | | | | | | |
| Adjustments and reconciling items | | | — | | | | — | | | | — | | | | — | |
| Consolidated loss from operations | | $ | (5,347 | ) | | $ | (5,864 | ) | | $ | (7,408 | ) | | $ | (9,940 | ) |
| | (1) | Includes expenses for travel, meals, dues, subscriptions, continuing education, and other miscellaneous expenses. |
| | (2) | Includes expenses for travel, meals, dues, subscriptions, continuing education, lobbying, banking fees, postage, and other office and miscellaneous expenses. |
Our revenue during the three and six months ended June 30, 2026 and 2025 was predominantly with a single customer, 4Life, through our Amended 4Life Agreements (see Note 15). A reconciliation of the total of the Products segment loss from operations to consolidated net loss before income taxes for the three and six months ended June 30, 2026 and 2025 was as follows:
| | | Three Months Ended June 30, | | | Six Months Ended June 30, | |
| (in thousands) | | 2026 | | | 2025 | | | 2026 | | | 2025 | |
| Segment loss from operations | | $ | (5,347 | ) | | $ | (5,864 | ) | | $ | (7,408 | ) | | $ | (9,940 | ) |
| Total other income (expense), net(1) | | | (8,077 | ) | | | (1,555 | ) | | | (14,107 | ) | | | 1,770 | |
| Net loss before income taxes | | $ | (13,424 | ) | | $ | (7,419 | ) | | $ | (21,515 | ) | | $ | (8,170 | ) |
| | (1) | Represents consolidated total other income (expense), net, as reported on the consolidated statements of operations and comprehensive loss. |
Products segment assets exclude corporate assets, such as cash, restricted cash, and corporate facilities. Total assets as of June 30, 2026 and December 31, 2025 were as follows:
| | | June 30, | | | December 31, | |
| (in thousands) | | 2026 | | | 2025 | |
| Total assets: | | | | | | | | |
| Products | | $ | 13,290 | | | $ | 12,828 | |
| Corporate | | | 9,751 | | | | 5,303 | |
| Consolidated | | $ | 23,041 | | | $ | 18,131 | |
Additions to long-lived assets during the six months ended June 30, 2026 were insignificant. We had no additions during the six months ended June 30, 2025.
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