Segment Reporting - Schedule of Segment Loss Including Significant Segment Expenses (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Segment Reporting [Abstract] | ||||||
| Navacaprant (NMRA-140) program | $ (13,308) | $ (22,257) | $ (34,218) | $ (46,750) | ||
| M4 PAM programs | (1,947) | (2,370) | (4,920) | (5,252) | ||
| NMRA-511 program | (1,075) | (2,257) | (2,293) | (4,837) | ||
| Preclinical programs | (3,022) | (1,459) | (5,704) | (2,461) | ||
| Research and development personnel-related costs | (8,786) | (7,617) | (18,165) | (19,943) | ||
| General and administrative expense | (12,907) | (15,316) | (27,173) | (34,101) | ||
| Interest income | 935 | 2,250 | 2,166 | 5,324 | ||
| Interest expense | (1,820) | (436) | (3,674) | (436) | ||
| Other segment items | (1,152) | (3,269) | (2,559) | (12,267) | ||
| Net loss | $ (43,082) | $ (53,458) | $ (52,731) | $ (67,992) | $ (96,540) | $ (120,723) |
| X | ||||||||||
- Definition M4 PAM programs expenses. No definition available.
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| X | ||||||||||
- Definition Navacaprant (NMRA-140) program expenses. No definition available.
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| X | ||||||||||
- Definition Navacaprant (NMRA-511) program expenses. No definition available.
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| X | ||||||||||
- Definition Other segment items. No definition available.
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| X | ||||||||||
- Definition Preclinical programs expenses. No definition available.
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| X | ||||||||||
- Definition Research and development personnel related costs. No definition available.
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| X | ||||||||||
- Definition The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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| X | ||||||||||
- Definition Amount of interest income (expense) classified as nonoperating. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of cash paid for interest, excluding capitalized interest, classified as operating activity. Includes, but is not limited to, payment to settle zero-coupon bond for accreted interest of debt discount and debt instrument with insignificant coupon interest rate in relation to effective interest rate of borrowing attributable to accreted interest of debt discount. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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| X | ||||||||||
- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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