v3.26.1
Material Agreements (Details)
1 Months Ended 6 Months Ended
Mar. 31, 2026
Jun. 30, 2025
USD ($)
Sep. 30, 2023
Jul. 31, 2023
USD ($)
May 31, 2023
USD ($)
Feb. 28, 2023
USD ($)
Oct. 31, 2022
USD ($)
Jul. 31, 2022
USD ($)
shares
Feb. 28, 2022
USD ($)
patient
patent
Jan. 31, 2022
USD ($)
patent
Feb. 28, 2018
patent
Jun. 30, 2026
USD ($)
Oct. 31, 2021
MaterialAgreements [Line Items]                          
Two year overall survival rate                 41.70%        
JHU-APL Technology License                          
MaterialAgreements [Line Items]                          
Number of issued patents | patent                     3    
Number of patent applications | patent                     1    
Warrant issuance percentage                         5.00%
New License Agreement                          
MaterialAgreements [Line Items]                          
Issuance of common stock, net of issuance costs (in shares) | shares               39,879          
Collaborative arrangement termination cure period               60 days          
New License Agreement | From 2023 through 2027                          
MaterialAgreements [Line Items]                          
Finite-lived patents, gross         $ 275,000                
New License Agreement | 2022                          
MaterialAgreements [Line Items]                          
Royalty expense               $ 30,000          
New License Agreement | 2023                          
MaterialAgreements [Line Items]                          
Royalty expense               80,000          
New License Agreement | 2024 and Beyond                          
MaterialAgreements [Line Items]                          
Royalty expense               $ 300,000          
New License Agreement | July 2023                          
MaterialAgreements [Line Items]                          
License payments       $ 75,000                  
New License Agreement | 2025                          
MaterialAgreements [Line Items]                          
License payments   $ 75,000                      
New License Agreement | 2026                          
MaterialAgreements [Line Items]                          
License payments         75,000                
New License Agreement | 2027                          
MaterialAgreements [Line Items]                          
License payments         50,000                
New License Agreement | June 2026                          
MaterialAgreements [Line Items]                          
Accrued royalties                       $ 150,000  
Accrued annual license fee                       4,167  
Annual license fee                       75,000  
New License Agreement | Maximum                          
MaterialAgreements [Line Items]                          
Sublicense percentage               50.00%          
New License Agreement | Minimum                          
MaterialAgreements [Line Items]                          
Sublicense percentage               25.00%          
New License Agreement | Minimum | 2023                          
MaterialAgreements [Line Items]                          
Royalty expense         $ 60,000                
New License Agreement | Internally Development Drug Projects                          
MaterialAgreements [Line Items]                          
Percentage of royalty on net sales               3.00%          
New License Agreement | Other Parties                          
MaterialAgreements [Line Items]                          
Percentage of royalty on net sales               8.00%          
George Washington University - Beta2-spectrin siRNA License Agreement                          
MaterialAgreements [Line Items]                          
Number of issued patents | patent                   3      
Percentage of royalty on net sales                   3.00%      
License initiation fee                   $ 20,000      
Accrued portion of annual license fees                       10,000  
Annual license maintenance fees                       20,000  
Johns Hopkins University - Mebendazole License Agreement                          
MaterialAgreements [Line Items]                          
Number of issued patents | patent                 6        
Number of patent applications | patent                 1        
Percentage of royalty on net sales                 3.50%        
Royalty expense                       50,000  
Accrued royalties                       25,000  
Number of patients enrolled | patient                 24        
Number of patients experiencing adverse effects | patient                 4        
Number of patients receiving maximum dose | patient                 15        
Four year overall survival rate                 25.00%        
Upfront license fee                 $ 250,000        
Payments for other fees                 50,000        
Payments for royalties                 250,000        
Johns Hopkins University - Mebendazole License Agreement | IPO                          
MaterialAgreements [Line Items]                          
License fee payment made after IPO           $ 200,000              
Johns Hopkins University - Mebendazole License Agreement | 2022                          
MaterialAgreements [Line Items]                          
Royalty expense                 5,000        
Johns Hopkins University - Mebendazole License Agreement | 2023                          
MaterialAgreements [Line Items]                          
Royalty expense                 10,000        
Johns Hopkins University - Mebendazole License Agreement | 2025                          
MaterialAgreements [Line Items]                          
Royalty expense                 30,000        
Johns Hopkins University - Mebendazole License Agreement | 2026                          
MaterialAgreements [Line Items]                          
Royalty expense                 50,000        
Johns Hopkins University - Mebendazole License Agreement | 2024                          
MaterialAgreements [Line Items]                          
Royalty expense                 $ 20,000        
Johns Hopkins University - Mebendazole License Agreement | Maximum                          
MaterialAgreements [Line Items]                          
Measurement period                 4 years        
Johns Hopkins University - Mebendazole License Agreement | Minimum                          
MaterialAgreements [Line Items]                          
Measurement period                 2 years        
Johns Hopkins University - Prodrug License Agreement                          
MaterialAgreements [Line Items]                          
Percentage of royalty on net sales             4.00%            
Accrued royalties                       2,500  
Upfront license fee             $ 100,000            
Payments for royalties             150,000            
Johns Hopkins University - Prodrug License Agreement | 2026                          
MaterialAgreements [Line Items]                          
Royalty expense             5,000            
Johns Hopkins University - Prodrug License Agreement | 2027                          
MaterialAgreements [Line Items]                          
Royalty expense             10,000            
Johns Hopkins University - Prodrug License Agreement | 2028                          
MaterialAgreements [Line Items]                          
Royalty expense             20,000            
Johns Hopkins University - Prodrug License Agreement | 2029                          
MaterialAgreements [Line Items]                          
Royalty expense             30,000            
Johns Hopkins University - Prodrug License Agreement | 2030                          
MaterialAgreements [Line Items]                          
Royalty expense             $ 50,000            
Johns Hopkins University - Prodrug License Agreement | Minimum                          
MaterialAgreements [Line Items]                          
Accrued royalties                       5,000  
Lieber Institute for Brain Development Partnership                          
MaterialAgreements [Line Items]                          
Initial term     1 year                    
Accrued royalties, current                       $ 36,000  
Feasibility Agreement                          
MaterialAgreements [Line Items]                          
Initial term 1 year                        
Research and development period 3 years