Aggregate beneficial ownership limitation percentage.

No definition available.

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Namespace Prefix:	apvo_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Ownership percentage.

+ References

No definition available.

+ Details

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Namespace Prefix:	apvo_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Reduction in research and development expense.

+ References

No definition available.

+ Details

Name:	apvo_ReductionInResearchAndDevelopmentExpense
Namespace Prefix:	apvo_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

Research and development cost percentage.

+ References

No definition available.

+ Details

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Namespace Prefix:	apvo_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Right to purchase additional shares.

+ References

No definition available.

+ Details

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Namespace Prefix:	apvo_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

Exercise price per share or per unit of warrants or rights outstanding.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-3

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 235
-SubTopic 10
-Name Accounting Standards Codification
-Section S50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480738/235-10-S50-1

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 235
-SubTopic 10
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.4-08(h)(4))
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147480678/235-10-S99-1

+ Details

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Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	instant

- Definition

Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147481112/505-10-50-3

+ Details

Name:	us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Namespace Prefix:	us-gaap_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 808
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479402/808-10-50-1

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

- Definition

Cash received on stock transaction after deduction of issuance costs.

+ References

No definition available.

+ Details

Name:	us-gaap_SaleOfStockConsiderationReceivedOnTransaction
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

The number of shares issued or sold by the subsidiary or equity method investee per stock transaction.

+ References

No definition available.

+ Details

Name:	us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction
Namespace Prefix:	us-gaap_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

- Definition

Per share amount received by subsidiary or equity investee for each share of common stock issued or sold in the stock transaction.

+ References

No definition available.

+ Details

Name:	us-gaap_SaleOfStockPricePerShare
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	instant

- Details

Name:	us-gaap_TypeOfArrangementAxis=apvo_StockPurchaseAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	srt_CounterpartyNameAxis=apvo_NiowaveMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_SubsidiarySaleOfStockAxis=us-gaap_PrivatePlacementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_TypeOfArrangementAxis=apvo_InvestorRightsAgreementMember
Namespace Prefix:
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Collaboration Agreements - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands		6 Months Ended
	May 25, 2026	Jun. 30, 2026	Jun. 30, 2025
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development expense		$ 50	$ 200
Percentage of cost related to research and development		50.00%	50.00%
Stock Purchase Agreement [Member] \| Niowave [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Number of shares sold	98,522
Warrants exercise price, per share	$ 8
Right to purcahse additional shares	97,373
Aggregate beneficial ownership limitation percentage	19.99%
Gross proceeds	$ 500
Stock Purchase Agreement [Member] \| Niowave [Member] \| Private Placement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Sale of stock per share	$ 5.075
Warrants to purchase common stock	53,201
Investor Rights Agreement [Member] \| Niowave [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Ownership percentage	19.99%