The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIVAX SA SPONSORED ADS 00370M103 2,781,003 20,869 SH SOLE 20,869 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104 1,040,000 250,000 SH SOLE 250,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 4,978,058 1,070,550 SH SOLE 1,070,550 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 7,215,040 721,504 SH SOLE 721,504 0 0
BIOFRONTERA INC COM NEW 09077D209 1,206,088 1,275,609 SH SOLE 1,275,609 0 0
CELLDEX THERAPEUTICS INC COM NEW 15117B202 7,442,000 200,000 SH SOLE 200,000 0 0
CYBIN INC COM NEW 23256X407 12,934,541 1,956,814 SH SOLE 1,956,814 0 0
DELCATH SYSTEMS, INC. COM NEW 24661P807 41,551,898 3,300,389 SH SOLE 3,300,389 0 0
EYEPOINT PHARMACEUTICALS INC COM NEW 30233G209 14,131,689 988,230 SH SOLE 988,230 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 34,271,011 3,188,001 SH SOLE 3,188,001 0 0
INSPIREMD INC COM 45779A846 2,734,411 3,905,743 SH SOLE 3,905,743 0 0
KURA ONCOLOGY INC COM 50127T109 1,097,000 100,000 SH SOLE 100,000 0 0
MEDIWOUND LTD SHS NEW M68830112 11,011,094 749,054 SH SOLE 749,054 0 0
MYOMO INC COM NEW 62857J201 3,783,401 3,637,886 SH SOLE 3,637,886 0 0
NEURAXIS INC COM 64134X201 2,971,106 508,055 SH SOLE 508,055 0 0
ONKURE THERAPEUTICS INC COM CL A 68277Q105 684,000 150,000 SH SOLE 150,000 0 0
OVID THERAPEUTICS INC COM 690469101 2,980,504 1,107,994 SH SOLE 1,107,994 0 0
PEPGEN INC COM 713317105 630,000 350,000 SH SOLE 350,000 0 0
POLYPID LTD COM M8001Q126 1,978,431 389,455 SH SOLE 389,455 0 0
PROFOUND MEDICAL CORP COM NEW 74319B502 5,506,985 828,118 SH SOLE 828,118 0 0
REGENTIS BIOMATERIALS LTD ORDINARY SHARES M8211G108 2,476,948 701,685 SH SOLE 701,685 0 0
SAVARA INC COM 805111101 19,577,225 3,178,121 SH SOLE 3,178,121 0 0
SPRUCE BIOSCIENCES INC COM NEW 85209E208 1,080,000 20,000 SH SOLE 20,000 0 0
TALPHERA INC COM NEW 00444T209 5,324,586 5,169,501 SH SOLE 5,169,501 0 0
VAXCYTE INC COM 92243G108 11,626,000 200,000 SH SOLE 200,000 0 0
VERASTEM INC COM NEW 92337C203 15,228,464 3,986,509 SH SOLE 3,986,509 0 0
VOR BIOPHARMA INC COM NEW 929033207 11,940,726 648,600 SH SOLE 648,600 0 0
X4 PHARMACEUTICALS INC COM NEW 98420X202 15,012,957 3,214,766 SH SOLE 3,214,766 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103 23,039,130 2,908,981 SH SOLE 2,908,981 0 0
CG ONCOLOGY INC CALL 156944900 375,100 31,000 SH Call SOLE 31,000 0 0
EYEPOINT PHARMACEUTICALS INC CALL 30233G909 130,780 50,300 SH Call SOLE 50,300 0 0
ISHARES TR PUT 464287955 110,000 500,000 SH Put SOLE 500,000 0 0
SELLAS LIFE SCIENCES GROUP INC PUT 81642T959 2,302,500 568,700 SH Put SOLE 568,700 0 0
TENAX THERAPEUTICS INC PUT 88032L955 13,950 6,200 SH Put SOLE 6,200 0 0
SPDR SERIES TRUST PUT 78464A950 35,150 140,600 SH Put SOLE 140,600 0 0