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  <xsd:element id="ptpi_NatureOfOperationsBasisOfPresentationAndLiquidityLineItems" name="NatureOfOperationsBasisOfPresentationAndLiquidityLineItems" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ptpi_WorkingCapital" name="WorkingCapital" nillable="true" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" xbrli:balance="debit" />
  <xsd:element id="ptpi_AccruedLiabilitiesTextBlock" name="AccruedLiabilitiesTextBlock" nillable="true" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ptpi_WarrantsAndRightsNoteDisclosureTextBlock" name="WarrantsAndRightsNoteDisclosureTextBlock" nillable="true" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ptpi_ClassOfWarrantOrRightIssued" name="ClassOfWarrantOrRightIssued" nillable="true" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" />
  <xsd:element id="ptpi_VivusIncMember" name="VivusIncMember" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ptpi_EarnoutPaymentsMethodAxis" name="EarnoutPaymentsMethodAxis" nillable="true" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" abstract="true" xbrli:periodType="duration" />
  <xsd:element id="ptpi_EarnoutPaymentsMethodDomain" name="EarnoutPaymentsMethodDomain" nillable="true" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" abstract="true" xbrli:periodType="duration" />
  <xsd:element name="SecuritiesPurchaseAgreementMember" id="ptpi_SecuritiesPurchaseAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsExercisedDuringPeriodValue" id="ptpi_WarrantsExercisedDuringPeriodValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ClassOfWarrantOrRightExpired" id="ptpi_ClassOfWarrantOrRightExpired" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SettlementAgreementMember" id="ptpi_SettlementAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PromissoryNoteMember" id="ptpi_PromissoryNoteMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ApiInventoryRetained" id="ptpi_ApiInventoryRetained" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PrepaymentAmount" id="ptpi_PrepaymentAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PaymentMadeForPurchaseOrder" id="ptpi_PaymentMadeForPurchaseOrder" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PercentageOfStendraTabletsReleased" id="ptpi_PercentageOfStendraTabletsReleased" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AccruedExpenseTable" id="ptpi_AccruedExpenseTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AccruedExpensesLineItem" id="ptpi_AccruedExpensesLineItem" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesConvertiblePreferredStockMember" id="ptpi_SeriesConvertiblePreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AggregateSharesOfPreferredStockAgreedToSell" id="ptpi_AggregateSharesOfPreferredStockAgreedToSell" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PreferredStockStatedValuePerShare" id="ptpi_PreferredStockStatedValuePerShare" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfEqualMonthlyInstallmentsForRedemptionOfPreferredStock" id="ptpi_NumberOfEqualMonthlyInstallmentsForRedemptionOfPreferredStock" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MinimumTradingDaysAfterDateThatInitialRegistrationStatementForConsideringFirstTradingDayOfCalendarMonth" id="ptpi_MinimumTradingDaysAfterDateThatInitialRegistrationStatementForConsideringFirstTradingDayOfCalendarMonth" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfRedemptionsPayableInCashOnInstallmentRedemptionAmount" id="ptpi_PercentageOfRedemptionsPayableInCashOnInstallmentRedemptionAmount" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfAverageOfThreeLowestClosingPricesOfCommonStockDuringThirtyTradingDayPeriodImmediatelyPriorToAmortizationPaymentIsDue" id="ptpi_PercentageOfAverageOfThreeLowestClosingPricesOfCommonStockDuringThirtyTradingDayPeriodImmediatelyPriorToAmortizationPaymentIsDue" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfTradingDaysImmediatelyPriorToAmortizationPaymentIsDueConsideredForCalculatingConversionPrice" id="ptpi_NumberOfTradingDaysImmediatelyPriorToAmortizationPaymentIsDueConsideredForCalculatingConversionPrice" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConversionPriceForValuationOfCommonStock" id="ptpi_ConversionPriceForValuationOfCommonStock" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PercentageOfMinimumPriceAsDefinedInNasdaqStockMarketRule" id="ptpi_PercentageOfMinimumPriceAsDefinedInNasdaqStockMarketRule" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="CommonStockClosingPricePerShareLimitForConversionOfStockFor20ConsecutiveTradingDays" id="ptpi_CommonStockClosingPricePerShareLimitForConversionOfStockFor20ConsecutiveTradingDays" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfTradingDayConsideredForCalculationOfClosingPriceLimitOfCommonStockForConversion" id="ptpi_NumberOfTradingDayConsideredForCalculationOfClosingPriceLimitOfCommonStockForConversion" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DailyDollarTradingVolumeOfCommonStockLimitForConversionOfStock" id="ptpi_DailyDollarTradingVolumeOfCommonStockLimitForConversionOfStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PreferredStockDividendsAccruedDividendPercentage" id="ptpi_PreferredStockDividendsAccruedDividendPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfPreferredStockAndDividendRedemption" id="ptpi_NumberOfPreferredStockAndDividendRedemption" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="AccrualOfSeriesConvertiblePreferredStockDividends" id="ptpi_AccrualOfSeriesConvertiblePreferredStockDividends" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PrivatePlacementTable" id="ptpi_PrivatePlacementTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PrivatePlacementLineItems" id="ptpi_PrivatePlacementLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsIssuanceCosts" id="ptpi_WarrantsIssuanceCosts" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NoncashRedemptionOfSeriesConvertiblePreferredStock" id="ptpi_NoncashRedemptionOfSeriesConvertiblePreferredStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ClassOfWarrantOrRightNumberOfWarrantsRollForward" id="ptpi_ClassOfWarrantOrRightNumberOfWarrantsRollForward" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsRollForward" id="ptpi_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsRollForward" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassOfWarrantOrRightAdditionalDisclosuresAbstract" id="ptpi_ClassOfWarrantOrRightAdditionalDisclosuresAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ClassOfWarrantOrRightRemainingContractualTerm" id="ptpi_ClassOfWarrantOrRightRemainingContractualTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsIssued" id="ptpi_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsIssued" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsExpired" id="ptpi_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsExpired" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PreferredStockRedemptionIncludingCashPremium" id="ptpi_PreferredStockRedemptionIncludingCashPremium" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PaymentDueForNotesPayableRelatedSecurityAgreement" id="ptpi_PaymentDueForNotesPayableRelatedSecurityAgreement" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PurchaseCommitmentForgivenessForReturnedGoods" id="ptpi_PurchaseCommitmentForgivenessForReturnedGoods" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DebtInstrumentAmountCoveredByCollateral" id="ptpi_DebtInstrumentAmountCoveredByCollateral" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ThresholdNumberOfDaysForTransferOfRegulatoryApprovalsForProduct" id="ptpi_ThresholdNumberOfDaysForTransferOfRegulatoryApprovalsForProduct" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="LiquidationFeesPayable" id="ptpi_LiquidationFeesPayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LiquidationCashFeePayableAsPercentageOfGrossSalesOfAssets" id="ptpi_LiquidationCashFeePayableAsPercentageOfGrossSalesOfAssets" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="SeriesBConvertibleRedeemablePreferredStockMember" id="ptpi_SeriesBConvertibleRedeemablePreferredStockMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PublicOfferingMember" id="ptpi_PublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesWarrantsMember" id="ptpi_SeriesWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesBWarrantsMember" id="ptpi_SeriesBWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PreFundedWarrantsMember" id="ptpi_PreFundedWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="UnitsMember" id="ptpi_UnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PreFundedUnitsMember" id="ptpi_PreFundedUnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="MinimumCashAndCashEquivalentsRequiredToBeMaintained" id="ptpi_MinimumCashAndCashEquivalentsRequiredToBeMaintained" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="debit" />
  <xsd:element name="NumberOfSharesPerUnit" id="ptpi_NumberOfSharesPerUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfWarrantsPerUnit" id="ptpi_NumberOfWarrantsPerUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="PreferredStockStatedValue" id="ptpi_PreferredStockStatedValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationNumberOfSegments" id="ptpi_DisposalGroupIncludingDiscontinuedOperationNumberOfSegments" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="StockIssuedDuringPeriodValueCommonStockAndPreFundedWarrants" id="ptpi_StockIssuedDuringPeriodValueCommonStockAndPreFundedWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="StockIssuedDuringPeriodSharesCommonStockAndPreFundedWarrants" id="ptpi_StockIssuedDuringPeriodSharesCommonStockAndPreFundedWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="BasisOfPresentationAndConsolidationPolicyPolicyTextBlock" id="ptpi_BasisOfPresentationAndConsolidationPolicyPolicyTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationSellingGeneralAndAdministrativeExpense" id="ptpi_DisposalGroupIncludingDiscontinuedOperationSellingGeneralAndAdministrativeExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopmentExpense" id="ptpi_DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopmentExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="MeasurementInputCashlessExerciseProbabilityMember" id="ptpi_MeasurementInputCashlessExerciseProbabilityMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ScenarioAlternativeCashlessExerciseMember" id="ptpi_ScenarioAlternativeCashlessExerciseMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="BrokerAndLegalFeesIncurredForIssuanceOfWarrants" id="ptpi_BrokerAndLegalFeesIncurredForIssuanceOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="FairValueOfWarrantsInExcessOfCashProceeds" id="ptpi_FairValueOfWarrantsInExcessOfCashProceeds" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="ClassOfWarrantOrRightAlternativeCashlessExerciseRatioForIssuanceOfWarrants" id="ptpi_ClassOfWarrantOrRightAlternativeCashlessExerciseRatioForIssuanceOfWarrants" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="DawsonJamesSecuritiesIncMember" id="ptpi_DawsonJamesSecuritiesIncMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CashFeeOnGrossProceedsFromPublicOfferingInPercentage" id="ptpi_CashFeeOnGrossProceedsFromPublicOfferingInPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="AdjustmentsToAdditionalPaidInCapitalDeemedDividendOfWarrants" id="ptpi_AdjustmentsToAdditionalPaidInCapitalDeemedDividendOfWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="DeemedDividendOnWarrants" id="ptpi_DeemedDividendOnWarrants" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="SeriesPreferredWarrantsMember" id="ptpi_SeriesPreferredWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="CashlessExerciseOfWarrantValue" id="ptpi_CashlessExerciseOfWarrantValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="CashlessExerciseOfWarrants" id="ptpi_CashlessExerciseOfWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProceedsFromIssuanceOrSaleOfEquityNet" id="ptpi_ProceedsFromIssuanceOrSaleOfEquityNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WarrantDeemedDividendIncomeStatementImpact" id="ptpi_WarrantDeemedDividendIncomeStatementImpact" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WarrantsAfterAntidilutionAdjustmentMember" id="ptpi_WarrantsAfterAntidilutionAdjustmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsBeforeAntidilutionAdjustmentMember" id="ptpi_WarrantsBeforeAntidilutionAdjustmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="WarrantsAntidilutionAdjustmentMember" id="ptpi_WarrantsAntidilutionAdjustmentMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="AbcAssetsMember" id="ptpi_AbcAssetsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="OperatingIncomeLossFromContinuingOperations" id="ptpi_OperatingIncomeLossFromContinuingOperations" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PreferredStockConvertibleInitialConversionPrice" id="ptpi_PreferredStockConvertibleInitialConversionPrice" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfLowestClosingPricesFromTradingDaysConsideredInDeterminationOfDiscountedMarketPrice" id="ptpi_NumberOfLowestClosingPricesFromTradingDaysConsideredInDeterminationOfDiscountedMarketPrice" type="xbrli:integerItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="Stockissuedduringperiodsharesroundedshares" id="ptpi_Stockissuedduringperiodsharesroundedshares" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="Stockissuedduringperiodvalueroundedshares" id="ptpi_Stockissuedduringperiodvalueroundedshares" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="RestrictedStockAwardsAndUnitsMember" id="ptpi_RestrictedStockAwardsAndUnitsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="Rule10b51ArrangementModifiedFlag" id="ptpi_Rule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NonRule10b51ArrangementModifiedFlag" id="ptpi_NonRule10b51ArrangementModifiedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightRemainingContractualIssuedTerm" id="ptpi_ClassOfWarrantOrRightRemainingContractualIssuedTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="WarrantLiabilityRecognizedUponIssuance" id="ptpi_WarrantLiabilityRecognizedUponIssuance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
</xsd:schema>
