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    <element id="CLDI_ProceedsReceivableFromAtMarketOffering" name="ProceedsReceivableFromAtMarketOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_UnauditedInterimFinancialInformationPolicyTextBlock" name="UnauditedInterimFinancialInformationPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_GovernmentGrantsPolicyTextBlock" name="GovernmentGrantsPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ForeignCurrencyTransactionGainsAndLossesPolicyTextBlock" name="ForeignCurrencyTransactionGainsAndLossesPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_NewAccountingPronouncementsIssuedButNotYetAdoptedPolicyTextBlock" name="NewAccountingPronouncementsIssuedButNotYetAdoptedPolicyTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_DiscloserOFCommonStockReservedForFurtureTableTextBlock" name="DiscloserOFCommonStockReservedForFurtureTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ScheduleOfOutstandingWarrantsTextBlock" name="ScheduleOfOutstandingWarrantsTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ScheduleOfCashFlowSupplementalDisclosuresOperatingAndFinancingLeasesTableTextBlock" name="ScheduleOfCashFlowSupplementalDisclosuresOperatingAndFinancingLeasesTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ScheduleOfSupplementalBalanceSheetInformationRelatedToOperatingAndFinancingLeasesTableTextBlock" name="ScheduleOfSupplementalBalanceSheetInformationRelatedToOperatingAndFinancingLeasesTableTextBlock" nillable="true" xbrli:periodType="duration" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_AccountingPoliciesTable" name="AccountingPoliciesTable" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" />
    <element id="CLDI_Consulting" name="Consulting" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_RentAndMaintenance" name="RentAndMaintenance" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ClinicalResearchAndDevelopment" name="ClinicalResearchAndDevelopment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ChangeInFairValueOfDebtOtherLiabilitiesAndDerivatives" name="ChangeInFairValueOfDebtOtherLiabilitiesAndDerivatives" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_OtherSegmentItems" name="OtherSegmentItems" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_AccruedCompensation" name="AccruedCompensation" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_AccruedVendorAndOtherExpenses" name="AccruedVendorAndOtherExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_PrepaidExpenses" name="PrepaidExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_PrepaidCAMReceivable" name="PrepaidCAMReceivable" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_PrepaidRestrictedCash" name="PrepaidRestrictedCash" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ConsultingPay" name="ConsultingPay" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_GuarantyOfLeaseAmount" name="GuarantyOfLeaseAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ClassOfWarrantOrRighstIssuanceDate" name="ClassOfWarrantOrRighstIssuanceDate" nillable="true" xbrli:periodType="duration" type="xbrli:dateItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_TriggeringEventAxis" name="TriggeringEventAxis" abstract="true" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrldt:dimensionItem" />
    <element id="CLDI_TriggeringEventDomain" name="TriggeringEventDomain" abstract="true" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_PublicWarrantRedemptionDescription" name="PublicWarrantRedemptionDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_RedemptionOfOutstandingWarrantsPerShare" name="RedemptionOfOutstandingWarrantsPerShare" nillable="true" xbrli:periodType="duration" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ClassOfWarrantsRedemptionNoticePeriod" name="ClassOfWarrantsRedemptionNoticePeriod" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionWeightedAverageGrantDateFairValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="instant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionOutstandingWeightedAverageRemainingContractualTerms" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionOutstandingWeightedAverageRemainingContractualTerms" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_CommonStockDividend" name="CommonStockDividend" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_PercentageOfStrategicInvestment" name="PercentageOfStrategicInvestment" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_CashCommissionPercentage" name="CashCommissionPercentage" nillable="true" xbrli:periodType="instant" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_DisbursementsCounsel" name="DisbursementsCounsel" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_IssuanceOfCommonSharesThroughAugustPublicOfferingShares" name="IssuanceOfCommonSharesThroughAugustPublicOfferingShares" nillable="true" xbrli:periodType="duration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_IssuanceOfCommonSharesThroughAugustPublicOfferingValue" name="IssuanceOfCommonSharesThroughAugustPublicOfferingValue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_CommonStockUnitPerShareDescription" name="CommonStockUnitPerShareDescription" nillable="true" xbrli:periodType="duration" type="xbrli:stringItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_AllocatedShareBasedCompensationExpenseResearchAndDevelopmentExpense" name="AllocatedShareBasedCompensationExpenseResearchAndDevelopmentExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_AllocatedShareBasedCompensationExpenseGeneralAndAdministrativeExpense" name="AllocatedShareBasedCompensationExpenseGeneralAndAdministrativeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_CommonStockDiscounRate" name="CommonStockDiscounRate" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_NoncashCompensation" name="NoncashCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_OperatingLeaseTermOfContractLeaseInitialTerm" name="OperatingLeaseTermOfContractLeaseInitialTerm" nillable="true" xbrli:periodType="duration" type="xbrli:durationItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_LeaseTermsOperatingLeasesAnnualIncreaseInRent" name="LeaseTermsOperatingLeasesAnnualIncreaseInRent" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_MonthlyRentalPayments" name="MonthlyRentalPayments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ManagementFeePercentage" name="ManagementFeePercentage" nillable="true" xbrli:periodType="duration" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_LetterOfCredit" name="LetterOfCredit" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_CashPaidForIncomeTaxes" name="CashPaidForIncomeTaxes" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_ForwardPurchaseAgreementDerivativeAssetMember" name="ForwardPurchaseAgreementDerivativeAssetMember" nillable="true" xbrli:periodType="duration" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_SeparationPay" name="SeparationPay" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwoAndThereafter" name="LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwoAndThereafter" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_LesseeOperatingLeaseLiabilityPaymentsDueYearFiveAndThereafter" name="LesseeOperatingLeaseLiabilityPaymentsDueYearFiveAndThereafter" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_FinanceLeaseLiabilityPaymentsDueYearFiveAndThereafter" name="FinanceLeaseLiabilityPaymentsDueYearFiveAndThereafter" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
    <element id="CLDI_RemainingExpectedCommitments" name="RemainingExpectedCommitments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" />
</schema>
