v3.26.1
Preferred Stock and Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
 6 Months Ended
Jun. 04, 2026
Apr. 10, 2026
Dec. 30, 2025
Nov. 13, 2025
Nov. 12, 2025
Sep. 20, 2024
Jun. 30, 2026
Jun. 30, 2025
Jun. 18, 2026
Jun. 17, 2026
Apr. 09, 2026
Mar. 31, 2026
Dec. 31, 2025
Jun. 10, 2025
Jun. 09, 2025
Mar. 31, 2025
Dec. 31, 2024
Apr. 28, 2023
Class Of Stock [Line Items]                                    
Common stock, shares authorized             450,000,000   450,000,000 300,000,000     300,000,000 300,000,000 200,000,000      
Common stock, shares issued             80,891,404           75,430,033          
Convertible preferred stock, shares authorized             5,000,000                      
Convertible preferred stock, par value             $ 0.001                      
Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Cashless exercise of pre-funded warrants   87,300                                
Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                    
Class Of Stock [Line Items]                                    
Proceeds from issuance offering       $ 57.5                            
Net proceeds after deducting offering costs         $ 53.6                          
Series X1 Non-voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Convertible preferred stock, shares authorized             515,000           515,000          
Convertible preferred stock, par value             $ 0.001           $ 0.001          
Convertible preferred stock, shares issued             75,800           110,086          
Convertible preferred stock, shares outstanding             75,800 110,086       110,086 110,086     110,086 110,086  
Series X Non-Voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Convertible preferred stock, shares authorized             10,000           10,000          
Convertible preferred stock, par value             $ 0.001           $ 0.001          
Convertible preferred stock, shares issued             4,422           4,422          
Convertible preferred stock, shares outstanding             4,422 4,422       4,422 4,422     4,422 4,422  
Common Stock [Member]                                    
Class Of Stock [Line Items]                                    
Shares of common stock issued upon conversion of each share of preferred stock             55.5556           55.5556          
Common stock, shares issued             655,943       1,248,832              
Common Stock [Member] | Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Common stock shares issued   87,269                                
Common Stock [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                    
Class Of Stock [Line Items]                                    
Warrant exercise price per share         $ 0.001                          
Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Shares of common stock issued upon conversion of each share of preferred stock             11,807       22,479              
Common Stock Warrants and Pre-Funded Warrants [Member]                                    
Class Of Stock [Line Items]                                    
Warrants available for exercise             48,693,790                      
Warrant exercise price per share             $ 3                      
Private Placement Warrants [Member] | Accredited Investor [Member]                                    
Class Of Stock [Line Items]                                    
Warrant exercise price per share                                   $ 3
Private Placement Warrants [Member] | Securities Purchase Agreement Initial Closing [Member] | Accredited Investor [Member]                                    
Class Of Stock [Line Items]                                    
Common stock, shares issued                                   15,151,518
Common stock warrants exercisable                                   15,151,518
Private Placement Warrants [Member] | Securities Purchase Agreement Second Closing [Member] | Accredited Investor [Member]                                    
Class Of Stock [Line Items]                                    
Common stock, shares issued                                   909,088
Private Placement Warrants [Member] | Securities Purchase Agreement Third Closing [Member] | Accredited Investor [Member]                                    
Class Of Stock [Line Items]                                    
Common stock, shares issued                                   1,727,400
2025 Warrant Exchange Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of stock, shares issued     4,203,764                              
Cashless exercise of pre-funded warrants 3,000,000                                  
2025 Warrant Exchange Agreement [Member] | Common Stock [Member]                                    
Class Of Stock [Line Items]                                    
Common stock shares issued 2,999,138                                  
2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member]                                    
Class Of Stock [Line Items]                                    
Common stock warrants exercisable     4,203,764                              
Cancelled common stock shares delivered in exchange of warrants     4,203,764                              
Underwritten Public Offering [Member] | Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of stock, shares issued         15,152,485                          
Stock price per share         $ 1.65                          
Warrant exercise price per share         $ 1.649                          
Maximum [Member] | Common Stock [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                    
Class Of Stock [Line Items]                                    
Common stock warrants exercisable         15,151,515                          
Maximum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of preferred stock, conversion blocker, percent               9.99%                    
Maximum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of preferred stock, conversion blocker, percent             9.99%                      
Maximum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Options issued to purchase common stock         4,545,600                          
Maximum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                    
Class Of Stock [Line Items]                                    
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage         19.99%                          
Maximum [Member] | 2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage     19.99%                              
Minimum [Member]                                    
Class Of Stock [Line Items]                                    
Percentage of exchange offer by third party to common stockholders             50.00%                      
Minimum [Member] | Common Stock [Member] | Series X1 Non-voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of preferred stock, conversion blocker, percent               9.90%                    
Minimum [Member] | Common Stock [Member] | Series X Non-Voting Convertible Preferred Stock [Member]                                    
Class Of Stock [Line Items]                                    
Conversion of preferred stock, conversion blocker, percent             9.90%                      
Minimum [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member] | Leerink Partners LLC [Member]                                    
Class Of Stock [Line Items]                                    
Class of Warrant Subject to Specified Beneficial Ownership Limitations Percentage         4.99%                          
Minimum [Member] | 2025 Warrant Exchange Agreement [Member] | Pre-funded Warrants [Member] | Underwriting Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Class of Warrant Subject to Specified Beneficial Ownership Limitations Permitted Percentage     4.99%                              
Guggenheim Securities LLC [Member] | Maximum [Member] | Equity Distribution Agreement [Member]                                    
Class Of Stock [Line Items]                                    
Proceeds from issuance of common stock           $ 75.0