| Segment Reporting |
The following table is the summary of the segment profit or loss information, including the significant expense categories for the three and six months ended June 30, 2026 and 2025, respectively: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | Three Months Ended
June 30, | | Six Months Ended
June 30, | | | 2026 | | 2025 | | 2026 | | 2025 | | Total revenues, net | | $ | 19,248 | | | $ | 18,839 | | | $ | 40,099 | | | $ | 41,872 | | | Significant operating expenses: | | | | | | | | | Cost of product sales(1) | | (2,104) | | | (836) | | | (5,571) | | | (2,897) | | Research and development(1) | | (15,958) | | | (29,605) | | | (34,953) | | | (57,540) | | Selling and marketing(1) | | (11,585) | | | (9,760) | | | (23,575) | | | (20,077) | | General and administrative(1) | | (7,574) | | | (7,632) | | | (16,009) | | | (16,395) | | | Restructuring and impairment expenses | | (2,674) | | | (13,091) | | | (2,674) | | | (13,091) | | | Share-based compensation | | (4,767) | | | (2,062) | | | (7,976) | | | (4,483) | | | Total operating expenses | | (44,662) | | | (62,986) | | | (90,758) | | | (114,483) | | | Loss from operations | | (25,414) | | | (44,147) | | | (50,659) | | | (72,611) | | Other segment items(2) | | 8,849 | | | (12,499) | | | 1,126 | | | (22,637) | | | Net loss | | $ | (16,565) | | | $ | (56,646) | | | $ | (49,533) | | | $ | (95,248) | |
(1)Excludes share-based compensation. (2)Includes Other expense, net, and Income tax expense.
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