0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Stockholders’ Equity (Deficit) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952156 - Disclosure - Description of Business link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Balance Sheet Accounts and Supplemental Disclosures link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Fair Value Measurements and Available for Sale Investments link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Indebtedness link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Licenses, Asset Acquisitions and Contingent Consideration link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Stockholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Equity Incentive Plans link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Significant Agreements and Contracts link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Investments in Variable Interest Entities link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Summary of Significant Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Balance Sheet Accounts and Supplemental Disclosures (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Fair Value Measurements and Available for Sale Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Indebtedness (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Equity Incentive Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Significant Agreements and Contracts (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Description of Business (Details) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Summary of Significant Accounting Policies - Schedule of Basic and Diluted Earnings (Loss) Per Common Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Summary of Significant Accounting Policies - Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Balance Sheet Accounts and Supplemental Disclosures (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Fair Value Measurements and Available for Sale Investments - Schedule of Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Fair Value Measurements and Available for Sale Investments - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Fair Value Measurements and Available for Sale Investments - Schedule of Available for sale Investments by Security Type (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Fair Value Measurements and Available for Sale Investments - Schedule of Contractual Maturities of Available-for-sale Debt Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Indebtedness - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Indebtedness - Schedule of Fair Value of the Derivative Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Indebtedness - Schedule of Net Carrying Amount of 2027 Notes (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Indebtedness - Schedule of Interest Expense Recognized (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Licenses, Asset Acquisitions and Contingent Consideration (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Stockholders’ Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Equity Incentive Plans - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Equity Incentive Plans - Schedule of Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Equity Incentive Plans - Schedule of Fair Value of the Derivative Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Equity Incentive Plans - Schedule of Restricted Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Equity Incentive Plans - Stock-Based Compensation Expense Reported in Condensed Consolidated Statements of Operations (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Equity Incentive Plans - Stock-Based Compensation Expense Reported in Condensed Consolidated Statements of Operations (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Commitments and Contingencies - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Commitments and Contingencies - Schedule of Lease Costs (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Commitments and Contingencies - Schedule of Gross Future Minimum Annual Rental Commitments (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Commitments and Contingencies - Schedule of Gross Future Minimum Annual Rental Commitments (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Significant Agreements and Contracts - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Significant Agreements and Contracts - Schedule of Contract Liability Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Significant Agreements and Contracts - Schedule of Revenues Disaggregated by Timing of Revenue Recognition (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Segment Information - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Segment Information - Schedule of Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Investments in Variable Interest Entities (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Subsequent Events (Details) link:presentationLink link:calculationLink link:definitionLink