Significant Agreements and Contracts - Schedule of Revenues Disaggregated by Timing of Revenue Recognition (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	$ 9,238	$ 11,489	$ 26,193	$ 21,378
Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	9,238	11,489	26,193	21,378
Revenue from PAH research and development service performance obligation satisfied during reporting period \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	2,623	3,356	9,680	6,145
Revenue from PH-ILD research and development service performance obligation satisfied during reporting period \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	486	586	1,089	1,133
Revenue from PAH research and development costs subject to reimbursement \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	3,595	3,186	6,053	7,598
Revenue from PH-ILD research and development costs subject to reimbursement \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	1,763	2,791	6,584	4,222
Revenue from PAH commercial costs subject to reimbursement \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	747	1,371	2,720	2,048
Revenue from PH-ILD commercial costs subject to reimbursement \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	0	231	0	295
Effect of exchange rate changes on revenue \| Over Time: \| Chiesi
Effect of exchange rate changes on revenue
Total revenue from Chiesi Collaboration Agreement	$ 24	$ (32)	$ 67	$ (63)