v3.26.1
Significant Agreements and Contracts - Additional Information (Details)
$ in Thousands
3 Months Ended 6 Months Ended 12 Months Ended
May 03, 2024
USD ($)
performanceObligation
license
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Jun. 30, 2026
USD ($)
Jun. 30, 2025
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2025
USD ($)
Effect of exchange rate changes on revenue              
Distinct performance obligations   $ 9,238 $ 11,489 $ 26,193 $ 21,378    
Current contract liabilities   7,068   7,068     $ 19,987
Long-term contract liabilities   30,155   30,155     29,606
Receivable from contracts with collaborators   6,105   6,105     12,227
Chiesi              
Effect of exchange rate changes on revenue              
Number of significant distinct performance obligations | performanceObligation 4            
Number of licenses granted | license 2            
Commercial efforts contribution, percentage 50.00%            
Commercialization activities performance, percentage 50.00%            
Up-front, nonrefundable payment received $ 160,000            
Loyalty term, expiration period 10 years            
Development cost reimbursement payment $ 160,000            
Contract with customer, liability, fair value of equity option $ 500            
Distinct performance obligations   9,238 11,489 26,193 21,378    
Contract liability   $ 37,223 54,967 $ 37,223 54,967 $ 55,919 $ 49,593
Revenue recognition period   4 years 6 months   4 years 6 months      
Receivable from contracts with collaborators   $ 6,100   $ 6,100      
Account receivable, payment term       30 days      
Chiesi | US License              
Effect of exchange rate changes on revenue              
Number of significant distinct performance obligations | performanceObligation 2            
Distinct performance obligations           $ 90,700  
Chiesi | Research and Development Services              
Effect of exchange rate changes on revenue              
Number of significant distinct performance obligations | performanceObligation 2            
Chiesi | PAH and PH-ILD Research and Development Services, Performance Obligations Satisfied              
Effect of exchange rate changes on revenue              
Distinct performance obligations   8,500 9,900 $ 23,400 19,100    
Chiesi | PAH and PH-ILD Commercialization Activities              
Effect of exchange rate changes on revenue              
Distinct performance obligations   $ 700 $ 1,600 $ 2,700 $ 2,300    
Chiesi | Maximum              
Effect of exchange rate changes on revenue              
Collaboration agreement, regulatory milestones receivable $ 146,000            
Collaboration agreement, sales milestones receivable $ 180,000