Segment Reporting - Schedule of Segment Profit or Loss, Including Segment Expenses (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||||
|---|---|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Segment Reporting [Line Items] | ||||||||
| Collaboration revenue | $ 2,082 | $ 1,907 | $ 3,381 | $ 3,536 | ||||
| Type of Revenue [Extensible List] | us-gaap:LicenseMember | us-gaap:LicenseMember | us-gaap:LicenseMember | us-gaap:LicenseMember | ||||
| Less: | ||||||||
| Total operating expenses | $ 33,216 | $ 38,875 | $ 67,515 | $ 81,784 | ||||
| Loss from operations | (31,134) | (36,968) | (64,134) | (78,248) | ||||
| Other income (expense): | ||||||||
| Interest income | 1,555 | 2,921 | 3,422 | 6,257 | ||||
| Change in fair value of stock price appreciation milestones | (580) | (73) | (660) | 207 | ||||
| Other income | 0 | (50) | 0 | (93) | ||||
| Total other income | 975 | 2,898 | 2,762 | 6,557 | ||||
| Net loss | (30,159) | $ (31,213) | (34,070) | $ (37,621) | (61,372) | (71,691) | ||
| Segment Reporting [Member] | ||||||||
| Segment Reporting [Line Items] | ||||||||
| Collaboration revenue | 2,082 | 1,907 | 3,381 | 3,536 | ||||
| Less: | ||||||||
| Personnel costs | 10,656 | 10,682 | 21,845 | 22,386 | ||||
| Clinical programs | 7,432 | 5,778 | 13,598 | 12,061 | ||||
| Research activities | 991 | 1,870 | 2,792 | 4,306 | ||||
| Facilities costs | 4,239 | 5,884 | 8,642 | 11,964 | ||||
| Other segment expenses | [1] | 9,898 | 14,661 | 20,638 | 31,067 | |||
| Total operating expenses | 33,216 | 38,875 | 67,515 | 81,784 | ||||
| Loss from operations | (31,134) | (36,968) | (64,134) | (78,248) | ||||
| Other income (expense): | ||||||||
| Interest income | 1,555 | 2,921 | 3,422 | 6,257 | ||||
| Change in fair value of stock price appreciation milestones | 580 | 73 | 660 | (207) | ||||
| Other income | 0 | (50) | 0 | (93) | ||||
| Total other income | 975 | 2,898 | 2,762 | 6,557 | ||||
| Net loss | $ (30,159) | $ (34,070) | $ (61,372) | $ (71,691) | ||||
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- Definition Clinical Programs, Expense No definition available.
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- Definition Facilities Costs No definition available.
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- Definition Increase decrease in fair value of stock price appreciation milestones. No definition available.
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- Definition Other Segment Expenses No definition available.
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- Definition Personnel Costs No definition available.
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- Definition Research Activities, Expense No definition available.
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- Definition Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- References No definition available.
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- References No definition available.
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- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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- Definition Amount of income related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Amount of income (expense) related to nonoperating activities, classified as other. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Definition Indicates type of revenue from product and service. Includes, but is not limited to, revenue from contract with customer and other sources. Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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- Details
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