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  <xs:element id="valn_ScheduleOfTradeAndOtherPayablesTableTextBlock" abstract="false" name="ScheduleOfTradeAndOtherPayablesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="valn_DisclosureOfDevelopmentOfRefundLiabilitiesTableTextBlock" abstract="false" name="DisclosureOfDevelopmentOfRefundLiabilitiesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="valn_ScheduleOfAdjustmentsToReconcileNetLossToNetCashGeneratedFromOperationsTableTextBlock" abstract="false" name="ScheduleOfAdjustmentsToReconcileNetLossToNetCashGeneratedFromOperationsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="valn_DisclosureOfGeneralInformationTable" abstract="true" name="DisclosureOfGeneralInformationTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="valn_IXIAROIXCHIQAndDUKORALMember" abstract="true" name="IXIAROIXCHIQAndDUKORALMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IXCHIQMember" abstract="true" name="IXCHIQMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_LymeVLA15Member" abstract="true" name="LymeVLA15Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_DisclosureOfGeneralInformationLineItems" abstract="true" name="DisclosureOfGeneralInformationLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_NumberOfTravelVaccines" abstract="false" name="NumberOfTravelVaccines" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_NumberOfCommercialVaccines" abstract="false" name="NumberOfCommercialVaccines" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_NumberOfAdultsVaccinated" abstract="false" name="NumberOfAdultsVaccinated" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_VaccineEfficacyRate" abstract="false" name="VaccineEfficacyRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ConfidenceIntervalLevelPercentage" abstract="false" name="ConfidenceIntervalLevelPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ReserveOfferingAmount" abstract="false" name="ReserveOfferingAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PotentialProceedsFromExerciseOfWarrants" abstract="false" name="PotentialProceedsFromExerciseOfWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ReductionInGlobalWorkforcePercentage" abstract="false" name="ReductionInGlobalWorkforcePercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_VaccinesHoldingsSwedenABMember" abstract="true" name="VaccinesHoldingsSwedenABMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaAustriaGmbHMember" abstract="true" name="ValnevaAustriaGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaCanadaIncMember" abstract="true" name="ValnevaCanadaIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaFranceSASMember" abstract="true" name="ValnevaFranceSASMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaScotlandLtdMember" abstract="true" name="ValnevaScotlandLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaSwedenABMember" abstract="true" name="ValnevaSwedenABMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaUKLtdMember" abstract="true" name="ValnevaUKLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ValnevaUSAIncMember" abstract="true" name="ValnevaUSAIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_VBC3ErrichtungsGmbHMember" abstract="true" name="VBC3ErrichtungsGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OtherRevenueFromContractWithCustomers" abstract="false" name="OtherRevenueFromContractWithCustomers" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherRevenueNotFromContractsWithCustomers" abstract="false" name="OtherRevenueNotFromContractsWithCustomers" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IXIAROMember" abstract="false" name="IXIAROMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_DUKORALMember" abstract="true" name="DUKORALMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ThirdPartyProductsMember" abstract="true" name="ThirdPartyProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IXCHIQChikungunyaVLA1553Member" abstract="true" name="IXCHIQChikungunyaVLA1553Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RoyaltiesReceivedMember" abstract="true" name="RoyaltiesReceivedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RevenuesFromShippingAndHandlingMember" abstract="true" name="RevenuesFromShippingAndHandlingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_MilestonePaymentLicensesMember" abstract="true" name="MilestonePaymentLicensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OthersProductsMember" abstract="true" name="OthersProductsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IXIAROJESPECTMember" abstract="true" name="IXIAROJESPECTMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenueFromSaleOfGoods" abstract="false" name="IncreaseDecreaseInRevenueFromSaleOfGoods" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenueFromSalesOfGoodsPercentage" abstract="false" name="IncreaseDecreaseInRevenueFromSalesOfGoodsPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenueFromSaleOfGoodsThroughForeignExchangeDifferences" abstract="false" name="IncreaseDecreaseInRevenueFromSaleOfGoodsThroughForeignExchangeDifferences" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInRevenue" abstract="false" name="IncreaseDecreaseInRevenue" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RestOfWorldMember" abstract="true" name="RestOfWorldMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_NordicsMember" abstract="true" name="NordicsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OtherEuropeMember" abstract="true" name="OtherEuropeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ConsultingAndOtherPurchasedServices" abstract="false" name="ConsultingAndOtherPurchasedServices" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CostOfServicesAndChangeInInventory" abstract="false" name="CostOfServicesAndChangeInInventory" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_EmployeeBenefitExpenseOtherThanShareBasedCompensation" abstract="false" name="EmployeeBenefitExpenseOtherThanShareBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_BuildingAndEnergyCosts" abstract="false" name="BuildingAndEnergyCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_SupplyOfficeAndITCosts" abstract="false" name="SupplyOfficeAndITCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_LicenseFeesAndRoyalties" abstract="false" name="LicenseFeesAndRoyalties" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_WarehousingAndDistributionCosts" abstract="false" name="WarehousingAndDistributionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TravelAndTransportationExpenses" abstract="false" name="TravelAndTransportationExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInCostOfServicesAndChangeInInventory" abstract="false" name="IncreaseDecreaseInCostOfServicesAndChangeInInventory" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInConsultingAndOtherPurchasedServices" abstract="false" name="IncreaseDecreaseInConsultingAndOtherPurchasedServices" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInEmployeeBenefitExpenseOtherThanShareBasedCompensation" abstract="false" name="IncreaseDecreaseInEmployeeBenefitExpenseOtherThanShareBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInExpenseFromShareBasedPaymentTransactionsWithEmployees" abstract="false" name="IncreaseDecreaseInExpenseFromShareBasedPaymentTransactionsWithEmployees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInAdvertisingExpenses" abstract="false" name="IncreaseDecreaseInAdvertisingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInDepreciationAmortisationAndImpairment" abstract="false" name="IncreaseDecreaseInDepreciationAmortisationAndImpairment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ResearchAndDevelopmentTaxCredit" abstract="false" name="ResearchAndDevelopmentTaxCredit" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ProfitLossFromRevaluationOfLeaseAgreements" abstract="false" name="ProfitLossFromRevaluationOfLeaseAgreements" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_MiscellaneousIncomeExpensesNet" abstract="false" name="MiscellaneousIncomeExpensesNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CoalitionForEpidemicPreparednessInnovationsCEPIMember" abstract="true" name="CoalitionForEpidemicPreparednessInnovationsCEPIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_StrategicPartnershipAgreementMember" abstract="true" name="StrategicPartnershipAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOtherOperatingIncomeExpense" abstract="false" name="IncreaseDecreaseInOtherOperatingIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInOtherOperatingIncomeExpensePercentage" abstract="false" name="IncreaseDecreaseInOtherOperatingIncomeExpensePercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_IncreaseDecreaseInResearchAndDevelopmentTaxCredit" abstract="false" name="IncreaseDecreaseInResearchAndDevelopmentTaxCredit" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_FinanceIncomeAbstract" abstract="true" name="FinanceIncomeAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_RealizedGainsFromCashAndCashEquivalents" abstract="false" name="RealizedGainsFromCashAndCashEquivalents" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_FinanceExpensesAbstract" abstract="true" name="FinanceExpensesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_InterestExpenseOnLoans" abstract="false" name="InterestExpenseOnLoans" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InterestExpenseOnRefundLiabilities" abstract="false" name="InterestExpenseOnRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherInterestExpense" abstract="false" name="OtherInterestExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateAppreciationDepreciationOfUSDollarAgainstEuro" abstract="false" name="ExchangeRateAppreciationDepreciationOfUSDollarAgainstEuro" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ManufacturingEquipmentMember" abstract="true" name="ManufacturingEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ResearchAndDevelopmentCostsMember" abstract="true" name="ResearchAndDevelopmentCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_InternalDevelopmentCostsMember" abstract="true" name="InternalDevelopmentCostsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_DisclosureOfInventoriesTable" abstract="true" name="DisclosureOfInventoriesTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="valn_DisclosureOfInventoriesLineItems" abstract="true" name="DisclosureOfInventoriesLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_CurrentPurchasedGoods" abstract="false" name="CurrentPurchasedGoods" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_GrossAmountOfInventoriesBeforeWriteDown" abstract="false" name="GrossAmountOfInventoriesBeforeWriteDown" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InventoriesWriteDownProvision" abstract="false" name="InventoriesWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CovidVLA2001ProductNettingMember" abstract="true" name="CovidVLA2001ProductNettingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_IXIARODUKORALAndIXCHIQMember" abstract="true" name="IXIARODUKORALAndIXCHIQMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_RawMaterialsWriteDownProvision" abstract="false" name="RawMaterialsWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RawMaterialsAndWorkInProgressWriteDownProvision" abstract="false" name="RawMaterialsAndWorkInProgressWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_FinishedGoodsWriteDownProvision" abstract="false" name="FinishedGoodsWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ShelfLifePeriod" abstract="false" name="ShelfLifePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="valn_WorkInProgressWriteDownProvision" abstract="false" name="WorkInProgressWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PurchasedGoodsWriteDownProvision" abstract="false" name="PurchasedGoodsWriteDownProvision" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_TradeReceivablesPastDue" abstract="false" name="TradeReceivablesPastDue" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseInTradeReceivables" abstract="false" name="IncreaseDecreaseInTradeReceivables" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ABSAMember" abstract="true" name="ABSAMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_EquityIssuanceSubscriptionPricePerShare" abstract="false" name="EquityIssuanceSubscriptionPricePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="valn_NumberOfSharesToBeIssuedOnExerciseOfOptionsOrWarrants" abstract="false" name="NumberOfSharesToBeIssuedOnExerciseOfOptionsOrWarrants" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="valn_NumberOfShareWarrantForEntityShare" abstract="false" name="NumberOfShareWarrantForEntityShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_ExercisePricePerShare" abstract="false" name="ExercisePricePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="valn_OtherRegulatedReservesMember" abstract="true" name="OtherRegulatedReservesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_OtherRevenueReserveMember" abstract="true" name="OtherRevenueReserveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_SharePremiumPerShare" abstract="false" name="SharePremiumPerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="valn_FairValuePerShare" abstract="false" name="FairValuePerShare" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="valn_WarrantExerciseRatio" abstract="false" name="WarrantExerciseRatio" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:decimalItemType"/>
  <xs:element id="valn_ExpectedVolatilityOtherEquityInstrumentsGranted" abstract="false" name="ExpectedVolatilityOtherEquityInstrumentsGranted" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_ExercisePricePremiumPercentage" abstract="false" name="ExercisePricePremiumPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_NonCurrentBorrowingsAbstract" abstract="true" name="NonCurrentBorrowingsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_DebenturesAndOtherLoansNonCurrent" abstract="false" name="DebenturesAndOtherLoansNonCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_CurrentBorrowingsAbstract" abstract="true" name="CurrentBorrowingsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_DebenturesAndOtherLoansCurrent" abstract="false" name="DebenturesAndOtherLoansCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PharmakonLoanAgreementDue2030Member" abstract="true" name="PharmakonLoanAgreementDue2030Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ResearchTaxCreditMember" abstract="true" name="ResearchTaxCreditMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_CEPIMember" abstract="true" name="CEPIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_NumberOfMilestonesNotExpectedToBeMet" abstract="false" name="NumberOfMilestonesNotExpectedToBeMet" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="valn_BorrowingFacilitiesMaximumBorrowingCapacity" abstract="false" name="BorrowingFacilitiesMaximumBorrowingCapacity" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_BorrowingsEffectiveInterestRate" abstract="false" name="BorrowingsEffectiveInterestRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="valn_BorrowingsTransactionCosts" abstract="false" name="BorrowingsTransactionCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PharmakonLoanDue2030AndAmendedDebtFinancingAgreementDue2028Member" abstract="true" name="PharmakonLoanDue2030AndAmendedDebtFinancingAgreementDue2028Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_GrossProceedsFromBorrowingsClassifiedAsFinancingActivities" abstract="false" name="GrossProceedsFromBorrowingsClassifiedAsFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseThroughTransactionCostsBorrowings" abstract="false" name="IncreaseDecreaseThroughTransactionCostsBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AccruedInterestOnBorrowings" abstract="false" name="AccruedInterestOnBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_IncreaseDecreaseThroughExchangeRateDifferenceBorrowings" abstract="false" name="IncreaseDecreaseThroughExchangeRateDifferenceBorrowings" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RevenueRecognitionContractLiabilities" abstract="false" name="RevenueRecognitionContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdditionsContractLiabilities" abstract="false" name="AdditionsContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateDifferencesContractLiabilities" abstract="false" name="ExchangeRateDifferencesContractLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AnalyticalSupportAndDrugSubstanceMember" abstract="true" name="AnalyticalSupportAndDrugSubstanceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_LicenceAgreementWithSerumInstituteOfIndiaSIIMember" abstract="true" name="LicenceAgreementWithSerumInstituteOfIndiaSIIMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AdditionsRefundLiability" abstract="false" name="AdditionsRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherReleasesRefundLiability" abstract="false" name="OtherReleasesRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_RevenueRecognitionRefundLiability" abstract="false" name="RevenueRecognitionRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_InterestExpenseCapitalizedRefundLiability" abstract="false" name="InterestExpenseCapitalizedRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ExchangeRateDifferenceRefundLiability" abstract="false" name="ExchangeRateDifferenceRefundLiability" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_PfizerIncMember" abstract="true" name="PfizerIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_GSKMember" abstract="true" name="GSKMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AmendedCollaborationAndLicenseAgreementMember" abstract="true" name="AmendedCollaborationAndLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_SupplyAgreementMember" abstract="true" name="SupplyAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_ReturnProvisionAndRebatesMember" abstract="true" name="ReturnProvisionAndRebatesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossFixedAssetsAndIntangibleAssets" abstract="false" name="AdjustmentsForImpairmentLossReversalOfImpairmentLossRecognisedInProfitOrLossFixedAssetsAndIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncomeTaxExpenseIncome" abstract="false" name="AdjustmentsForIncomeTaxExpenseIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForGainLossOnDisposalsOfPropertyPlantAndEquipmentAndIntangibleAssets" abstract="false" name="AdjustmentsForGainLossOnDisposalsOfPropertyPlantAndEquipmentAndIntangibleAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentForGainLossFromMMFInvestments" abstract="false" name="AdjustmentForGainLossFromMMFInvestments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForEmployerContributionCostsOnShareBasedCompensationPlans" abstract="false" name="AdjustmentsForEmployerContributionCostsOnShareBasedCompensationPlans" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_OtherAdjustmentsForNonCashIncomeExpense" abstract="false" name="OtherAdjustmentsForNonCashIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ChangesInNonCurrentOperatingAssetsAndLiabilitiesExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" abstract="true" name="ChangesInNonCurrentOperatingAssetsAndLiabilitiesExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_AdjustmentsForDecreaseIncreaseInOtherNonCurrentAssets" abstract="false" name="AdjustmentsForDecreaseIncreaseInOtherNonCurrentAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInLongTermRefundLiabilities" abstract="false" name="AdjustmentsForIncreaseDecreaseInLongTermRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInOtherNonCurrentLiabilitiesAndProvisions" abstract="false" name="AdjustmentsForIncreaseDecreaseInOtherNonCurrentLiabilitiesAndProvisions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_ChangesInWorkingCapitalExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" abstract="true" name="ChangesInWorkingCapitalExcludingTheEffectsOfAcquisitionAndExchangeRateDifferencesOnConsolidationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInRefundLiabilities" abstract="false" name="AdjustmentsForIncreaseDecreaseInRefundLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_AdjustmentsForIncreaseDecreaseInOtherPayablesAndProvisions" abstract="false" name="AdjustmentsForIncreaseDecreaseInOtherPayablesAndProvisions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="valn_BPIFranceMember" abstract="true" name="BPIFranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="valn_BorrowingsGrantedPercentageOfReceivables" abstract="false" name="BorrowingsGrantedPercentageOfReceivables" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
</xs:schema>
