For the Three Months Ended June 30, |
For the Six Months Ended June 30, |
|||||||||||||||||||
Notes |
2026 |
2025 |
2026 |
2025 |
||||||||||||||||
(in thousands, except per share data) |
||||||||||||||||||||
£ |
£ |
£ |
£ |
|||||||||||||||||
Research and development expenses |
( |
) | ( |
) | ( |
) | ( |
) | ||||||||||||
Administrative expenses |
( |
) | ( |
) | ( |
) | ( |
) | ||||||||||||
Net foreign exchange (losses) gains |
( |
) | ( |
) | ( |
) | ||||||||||||||
Operating loss |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||||||
Finance income |
||||||||||||||||||||
Finance expense |
3 | ( |
) | ( |
) | |||||||||||||||
Loss before tax |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||||||
Income tax credit |
4 | |||||||||||||||||||
Loss for the period attributable to equity holders of the Company |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||||||
Basic and diluted loss per ordinary share |
5 | ( |
) | ( |
) | ( |
) | ( |
) | |||||||||||
For the Three Months Ended June 30, |
For the Six Months Ended June 30, |
|||||||||||||||
2026 |
2025 |
2026 |
2025 |
|||||||||||||
(in thousands) |
||||||||||||||||
£ |
£ |
£ |
£ |
|||||||||||||
Loss for the period |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||
Other comprehensive (expense) income: |
||||||||||||||||
Items that may be reclassified subsequently to profit or loss: |
||||||||||||||||
Exchange differences on translation of foreign operations |
( |
) | ( |
) | ( |
) | ||||||||||
Other comprehensive (expense) income for the period |
( |
) | ( |
) | ( |
) | ||||||||||
Total comprehensive loss for the period |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||
Attributable to: |
||||||||||||||||
Equity holders of the Company |
( |
) |
( |
) |
( |
) |
( |
) | ||||||||
June 30, 2026 |
December 31, 2025 |
|||||||||||
(in thousands) |
||||||||||||
Notes |
£ |
£ |
||||||||||
Assets |
||||||||||||
Non-current assets |
||||||||||||
Intangible assets |
6 | |||||||||||
Property, plant and equipment |
||||||||||||
Deferred tax asset |
4 | |||||||||||
Current assets |
||||||||||||
Prepayments, accrued income and other receivables |
||||||||||||
Current income tax receivable |
4 | |||||||||||
Cash and cash equivalents |
7 | |||||||||||
Total assets |
||||||||||||
Equity and liabilities |
||||||||||||
Capital and reserves |
||||||||||||
Share capital and share premium |
9 | |||||||||||
Other reserves |
||||||||||||
Accumulated deficit |
( |
) | ( |
) | ||||||||
Total equity attributable to equity holders of the Company |
||||||||||||
Non-current liabilities |
||||||||||||
Provisions |
||||||||||||
Lease liabilities |
||||||||||||
Current liabilities |
||||||||||||
Trade payables |
||||||||||||
Payroll taxes and social security |
||||||||||||
Accrued expenditure |
||||||||||||
Lease liabilities |
||||||||||||
Total liabilities |
||||||||||||
Total equity and liabilities |
||||||||||||
For the Six Months Ended June 30, |
||||||||||||||||||||||||||||||||
Share capital |
Share premium |
Own share reserve |
Share option reserve |
Foreign currency translation reserve |
Capital reserve |
Accumulated deficit |
Total equity attributable to equity holders |
|||||||||||||||||||||||||
(in thousands) |
||||||||||||||||||||||||||||||||
£ |
£ |
£ |
£ |
£ |
£ |
£ |
£ |
|||||||||||||||||||||||||
Balance at January 1, 2025 |
( |
) |
( |
) |
||||||||||||||||||||||||||||
Loss for the period |
— | — | — | — | — | — | ( |
) | ( |
) | ||||||||||||||||||||||
Other comprehensive expense for the period |
— | — | — | — | ( |
) | — | — | ( |
) | ||||||||||||||||||||||
Total comprehensive loss for the period |
— | — | — | — | ( |
) | — | ( |
) | ( |
) | |||||||||||||||||||||
Share-based payments |
— | — | — | — | — | — | ||||||||||||||||||||||||||
Exercise of share options |
— | — | ( |
) | — | — | ||||||||||||||||||||||||||
Lapse of share options |
— | — | — | ( |
) | — | — | — | ||||||||||||||||||||||||
Issue of share capital |
— | — | — | — | — | |||||||||||||||||||||||||||
Exercise of warrants |
— | — | — | — | — | |||||||||||||||||||||||||||
Share issue expenses |
— | ( |
) | — | — | — | — | — | ( |
) | ||||||||||||||||||||||
Balance at June 30, 2025 |
( |
) |
( |
) |
( |
) |
||||||||||||||||||||||||||
Balance at January 1, 2026 |
( |
) |
( |
) |
( |
) |
||||||||||||||||||||||||||
Loss for the period |
— | — | — | — | — | — | ( |
) | ( |
) | ||||||||||||||||||||||
Other comprehensive income for the period |
— | — | — | — | — | — | ||||||||||||||||||||||||||
Total comprehensive loss for the period |
— | — | — | — | — | ( |
) | ( |
) | |||||||||||||||||||||||
Share-based payments |
— | — | — | — | — | — | ||||||||||||||||||||||||||
Lapse of share options |
— | — | — | ( |
) | — | — | — | ||||||||||||||||||||||||
Issue of share capital |
— | — | — | — | — | |||||||||||||||||||||||||||
Share issue expenses |
— | ( |
) | — | — | — | — | — | ( |
) | ||||||||||||||||||||||
Balance at June 30, 2026 |
( |
) |
( |
) |
( |
) |
||||||||||||||||||||||||||
For the Six Months Ended June 30, |
||||||||
2026 |
2025 |
|||||||
(in thousands) |
||||||||
£ |
£ |
|||||||
Cash flows from operating activities |
||||||||
Loss for the period |
( |
) | ( |
) | ||||
Adjustments for: |
||||||||
Income tax credit |
( |
) | ( |
) | ||||
Amortization and depreciation |
||||||||
Movement in provisions |
( |
) | ||||||
Finance income |
( |
) | ( |
) | ||||
Finance expense |
||||||||
Interest expense on lease liabilities |
||||||||
Share-based payments |
||||||||
Net foreign exchange (gains) losses |
( |
) | ||||||
| ( |
) | ( |
) | |||||
Movements in working capital: |
||||||||
Decrease (increase) in prepayments, accrued income and other receivables |
( |
) | ||||||
Decrease in trade payables |
( |
) | ( |
) | ||||
Increase (decrease) in payroll taxes, social security and accrued expenditure |
( |
) | ||||||
Movements in working capital |
( |
) | ||||||
Cash used in operations |
( |
) |
( |
) | ||||
Net income tax received |
||||||||
Net cash used in operating activities |
( |
) |
( |
) | ||||
Cash flows from investing activities |
||||||||
Interest received |
||||||||
Payments for intangible assets |
( |
) | ( |
) | ||||
Net cash from (used in) investing activities |
( |
) | ||||||
Cash flows from financing activities |
||||||||
Payments for lease liabilities |
( |
) | ( |
) | ||||
Proceeds from exercise of share options |
||||||||
Proceeds from issue of share capital |
||||||||
Proceeds from exercise of warrants |
||||||||
Proceeds from issue of warrants |
||||||||
Share issue expenses |
( |
) | ( |
) | ||||
Net cash from financing activities |
||||||||
Net (decrease) increase in cash and cash equivalents |
( |
) | ||||||
Cash and cash equivalents at beginning of period |
||||||||
Effect of exchange rate changes on cash and cash equivalents |
( |
) | ||||||
Cash and cash equivalents at end of period |
||||||||
For the Three Months Ended June 30, |
For the Six Months Ended June 30, |
|||||||||||||||
2026 |
2025 |
2026 |
2025 |
|||||||||||||
(in thousands) |
||||||||||||||||
£ |
£ |
£ |
£ |
|||||||||||||
| Revaluation loss from derivative financial instruments |
( |
) | ( |
) | ||||||||||||
| |
|
|
|
|
|
|
|
|||||||||
For the Three Months Ended June 30, |
For the Six Months Ended June 30, |
|||||||||||||||
2026 |
2025 |
2026 |
2025 |
|||||||||||||
(in thousands) |
||||||||||||||||
£ |
£ |
£ |
£ |
|||||||||||||
| Current tax: |
||||||||||||||||
| In respect of current period U.K. |
||||||||||||||||
| In respect of prior period U.K. |
— | — | ||||||||||||||
| |
|
|
|
|
|
|
|
|||||||||
| Deferred tax: |
||||||||||||||||
| In respect of current period U.S. |
||||||||||||||||
| |
|
|
|
|
|
|
|
|||||||||
| Income tax credit |
||||||||||||||||
| |
|
|
|
|
|
|
|
|||||||||
June 30, 2026 |
December 31, 2025 |
|||||||
(in thousands) |
||||||||
£ |
£ |
|||||||
Current income tax receivable |
||||||||
U.K. tax |
||||||||
U.S. tax |
||||||||
Deferred tax asset |
||||||||
U.S. deferred tax asset |
||||||||
For the Three Months Ended June 30, |
For the Six Months Ended June 30, |
|||||||||||||||
2026 |
2025 |
2026 |
2025 |
|||||||||||||
(in thousands, except per share data) |
||||||||||||||||
£ |
£ |
£ |
£ |
|||||||||||||
Loss for the period |
( |
) | ( |
) | ( |
) | ( |
) | ||||||||
Basic and diluted weighted average number of ordinary shares |
||||||||||||||||
Basic and diluted loss per ordinary share |
( |
) | ( |
) | ( |
) | ( |
) | ||||||||
June 30, 2026 |
December 31, 2025 |
|||||||
(in thousands) |
||||||||
£ |
£ |
|||||||
Cash and cash equivalents |
||||||||
Grant date |
Jan-14-2026 |
Jan-14-2026 |
Jan-14-2026 |
|||||||||||||||||
Vesting dates |
||||||||||||||||||||
| — | — | |||||||||||||||||||
| — | — | |||||||||||||||||||
| — | — | |||||||||||||||||||
Volatility 1 |
% | % | % | |||||||||||||||||
Dividend yield |
% | % | % | |||||||||||||||||
Risk-free investment rate 1 |
% | % | % | |||||||||||||||||
Fair value of option at grant date 1 |
£ | £ | £ | |||||||||||||||||
Fair value of share at grant date |
£ | £ | £ | |||||||||||||||||
Exercise price at date of grant |
£ | £ | £ | |||||||||||||||||
Lapse date |
||||||||||||||||||||
Expected option life (years) 1 |
||||||||||||||||||||
Number of options granted |
||||||||||||||||||||
Grant date |
Jan-14-2026 |
Jan-14-2026 |
||||||||||||||||
Vesting dates |
||||||||||||||||||
| — | ||||||||||||||||||
| — | ||||||||||||||||||
| — | ||||||||||||||||||
Volatility 1 |
% | % | ||||||||||||||||
Dividend yield |
% | % | ||||||||||||||||
Risk-free investment rate 1 |
% | % | ||||||||||||||||
Fair value of option at grant date 1 |
£ | £ | ||||||||||||||||
Fair value of share at grant date |
£ | £ | ||||||||||||||||
Exercise price at date of grant |
£ | £ | ||||||||||||||||
Lapse date |
||||||||||||||||||
Expected option life (years) 1 |
||||||||||||||||||
Number of options granted |
||||||||||||||||||
Grant date |
Apr-15-2026 |
Apr-15-2026 |
||||||||||||||||
Vesting dates |
||||||||||||||||||
| — | ||||||||||||||||||
| — | ||||||||||||||||||
| — | ||||||||||||||||||
Volatility 1 |
% | % | ||||||||||||||||
Dividend yield |
% | % | ||||||||||||||||
Risk-free investment rate 1 |
% | % | ||||||||||||||||
Fair value of option at grant date 1 |
£ | £ | ||||||||||||||||
Fair value of share at grant date |
£ | £ | ||||||||||||||||
Exercise price at date of grant |
£ | £ | ||||||||||||||||
Lapse date |
||||||||||||||||||
Expected option life (years) 1 |
||||||||||||||||||
Number of options granted |
||||||||||||||||||
1. |
Represents the average for the options granted. |
June 30, 2026 |
December 31, 2025 |
|||||||
(in thousands) |
||||||||
£ |
£ |
|||||||
Share capital |
||||||||
Share premium |
||||||||
Number (in thousands) |
||||||||
Nominal value £ |
Nominal value £ |
|||||||
Issued share capital comprises: |
||||||||
Ordinary shares |
||||||||
Deferred shares |
||||||||
Number of ordinary shares |
Number of deferred shares |
Ordinary share capital |
Deferred share capital |
Share premium |
||||||||||||||||
(in thousands) |
||||||||||||||||||||
£ |
£ |
£ |
||||||||||||||||||
Fully paid shares: |
||||||||||||||||||||
Balance at December 31, 2025 |
||||||||||||||||||||
Subdivision and reclassification of share capital |
( |
) | ||||||||||||||||||
Issue of share capital |
||||||||||||||||||||
Share issue expenses |
— | — |
— | — | ( |
) | ||||||||||||||
Balance at June 30, 2026 |
||||||||||||||||||||
| • | Each of the sub-divided into |
| • | Each of the the Company was sub-divided into and redesignated as |