3.26.1 html 156 188 1 false 36 0 false 5 false false R1.htm 995300 - Document - Document and Entity Information Sheet http://polaryxtherapeuticsinc.com/20260630/role/DocumentandEntityInformation Document and Entity Information Cover 1 false false R2.htm 995301 - Statement - Condensed Balance Sheets (Unaudited) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CondensedBalanceSheetsUnaudited Condensed Balance Sheets (Unaudited) Statements 2 false false R3.htm 995302 - Statement - Condensed Balance Sheets (Unaudited) (Parentheticals) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CondensedBalanceSheetsUnauditedParentheticals Condensed Balance Sheets (Unaudited) (Parentheticals) Statements 3 false false R4.htm 995303 - Statement - Condensed Statements of Operations and Comprehensive Loss (Unaudited) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CondensedStatementsofOperationsandComprehensiveLossUnaudited Condensed Statements of Operations and Comprehensive Loss (Unaudited) Statements 4 false false R5.htm 995304 - Statement - Condensed Statements of Changes in Stockholders’ Equity (Unaudited) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CondensedStatementsofChangesinStockholdersEquityUnaudited Condensed Statements of Changes in Stockholders’ Equity (Unaudited) Statements 5 false false R6.htm 995305 - Statement - Condensed Statements of Cash Flows (Unaudited) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CondensedStatementsofCashFlowsUnaudited Condensed Statements of Cash Flows (Unaudited) Statements 6 false false R7.htm 995306 - Disclosure - Nature of the Business and Basis of Presentation Sheet http://polaryxtherapeuticsinc.com/20260630/role/NatureoftheBusinessandBasisofPresentation Nature of the Business and Basis of Presentation Notes 7 false false R8.htm 995307 - Disclosure - Summary of Significant Accounting Policies Sheet http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPolicies Summary of Significant Accounting Policies Notes 8 false false R9.htm 995308 - Disclosure - Accrued Expenses and Other Current Liabilities Sheet http://polaryxtherapeuticsinc.com/20260630/role/AccruedExpensesandOtherCurrentLiabilities Accrued Expenses and Other Current Liabilities Notes 9 false false R10.htm 995309 - Disclosure - Stockholders’ Equity Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockholdersEquity Stockholders’ Equity Notes 10 false false R11.htm 995310 - Disclosure - Stock-Based Compensation Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensation Stock-Based Compensation Notes 11 false false R12.htm 995311 - Disclosure - Segment Information Sheet http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformation Segment Information Notes 12 false false R13.htm 995312 - Disclosure - Net Loss Per Share Sheet http://polaryxtherapeuticsinc.com/20260630/role/NetLossPerShare Net Loss Per Share Notes 13 false false R14.htm 995313 - Disclosure - Income Taxes Sheet http://polaryxtherapeuticsinc.com/20260630/role/IncomeTaxes Income Taxes Notes 14 false false R15.htm 995314 - Disclosure - Commitments and Contingencies Sheet http://polaryxtherapeuticsinc.com/20260630/role/CommitmentsandContingencies Commitments and Contingencies Notes 15 false false R16.htm 995315 - Disclosure - Related Parties Sheet http://polaryxtherapeuticsinc.com/20260630/role/RelatedParties Related Parties Notes 16 false false R17.htm 995316 - Disclosure - Subsequent Events Sheet http://polaryxtherapeuticsinc.com/20260630/role/SubsequentEvents Subsequent Events Notes 17 false false R18.htm 995410 - Disclosure - Pay vs Performance Disclosure Sheet http://xbrl.sec.gov/ecd/role/PvpDisclosure Pay vs Performance Disclosure Notes 18 false false R19.htm 995445 - Disclosure - Insider Trading Arrangements Sheet http://xbrl.sec.gov/ecd/role/InsiderTradingArrangements Insider Trading Arrangements Notes 19 false false R20.htm 996317 - Disclosure - Summary of Significant Accounting Policies (Policies) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPoliciesPolicies Summary of Significant Accounting Policies (Policies) Policies http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPolicies 20 false false R21.htm 996318 - Disclosure - Summary of Significant Accounting Policies (Tables) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPoliciesTables Summary of Significant Accounting Policies (Tables) Tables http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPolicies 21 false false R22.htm 996319 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables) Sheet http://polaryxtherapeuticsinc.com/20260630/role/AccruedExpensesandOtherCurrentLiabilitiesTables Accrued Expenses and Other Current Liabilities (Tables) Tables http://polaryxtherapeuticsinc.com/20260630/role/AccruedExpensesandOtherCurrentLiabilities 22 false false R23.htm 996320 - Disclosure - Stock-Based Compensation (Tables) Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensationTables Stock-Based Compensation (Tables) Tables http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensation 23 false false R24.htm 996321 - Disclosure - Segment Information (Tables) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformationTables Segment Information (Tables) Tables http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformation 24 false false R25.htm 996322 - Disclosure - Net Loss per Share (Tables) Sheet http://polaryxtherapeuticsinc.com/20260630/role/NetLossperShareTables Net Loss per Share (Tables) Tables 25 false false R26.htm 996323 - Disclosure - Nature of the Business and Basis of Presentation (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/NatureoftheBusinessandBasisofPresentationDetails Nature of the Business and Basis of Presentation (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/NatureoftheBusinessandBasisofPresentation 26 false false R27.htm 996324 - Disclosure - Summary of Significant Accounting Policies (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPoliciesDetails Summary of Significant Accounting Policies (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPoliciesTables 27 false false R28.htm 996325 - Disclosure - Summary of Significant Accounting Policies - Schedule of Depreciation and Amortization Over Estimated Useful Lives of Property and Equipment, Net (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SummaryofSignificantAccountingPoliciesScheduleofDepreciationandAmortizationOverEstimatedUsefulLivesofPropertyandEquipmentNetDetails Summary of Significant Accounting Policies - Schedule of Depreciation and Amortization Over Estimated Useful Lives of Property and Equipment, Net (Details) Details 28 false false R29.htm 996326 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Components Accrued Expenses and Other Current Liabilities (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/AccruedExpensesandOtherCurrentLiabilitiesScheduleofComponentsAccruedExpensesandOtherCurrentLiabilitiesDetails Accrued Expenses and Other Current Liabilities - Schedule of Components Accrued Expenses and Other Current Liabilities (Details) Details 29 false false R30.htm 996327 - Disclosure - Stockholders’ Equity (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockholdersEquityDetails Stockholders’ Equity (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/StockholdersEquity 30 false false R31.htm 996328 - Disclosure - Stock-Based Compensation (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensationDetails Stock-Based Compensation (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensationTables 31 false false R32.htm 996329 - Disclosure - Stock-Based Compensation - Schedule of Restricted Stock Activity (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/StockBasedCompensationScheduleofRestrictedStockActivityDetails Stock-Based Compensation - Schedule of Restricted Stock Activity (Details) Details 32 false false R33.htm 996330 - Disclosure - Segment Information (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformationDetails Segment Information (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformationTables 33 false false R34.htm 996331 - Disclosure - Segment Information - Schedule of Significant Segment Expenses (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/SegmentInformationScheduleofSignificantSegmentExpensesDetails Segment Information - Schedule of Significant Segment Expenses (Details) Details 34 false false R35.htm 996332 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/NetLossPerShareScheduleofBasicandDilutedNetLossPerShareDetails Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Details) Details 35 false false R36.htm 996333 - Disclosure - Net Loss Per Share - Schedule of Net Loss Per Share due to their Anti-dilutive Effect (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/NetLossPerShareScheduleofNetLossPerShareduetotheirAntidilutiveEffectDetails Net Loss Per Share - Schedule of Net Loss Per Share due to their Anti-dilutive Effect (Details) Details 36 false false R37.htm 996334 - Disclosure - Income Taxes (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/IncomeTaxesDetails Income Taxes (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/IncomeTaxes 37 false false R38.htm 996335 - Disclosure - Commitments and Contingencies (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/CommitmentsandContingenciesDetails Commitments and Contingencies (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/CommitmentsandContingencies 38 false false R39.htm 996336 - Disclosure - Related Parties (Details) Sheet http://polaryxtherapeuticsinc.com/20260630/role/RelatedPartiesDetails Related Parties (Details) Details http://polaryxtherapeuticsinc.com/20260630/role/RelatedParties 39 false false All Reports Book All Reports ea0301429-10q_polaryx.htm plyx-20260630.xsd plyx-20260630_cal.xml plyx-20260630_def.xml plyx-20260630_lab.xml plyx-20260630_pre.xml http://fasb.org/us-gaap/2026 http://xbrl.sec.gov/dei/2026 http://xbrl.sec.gov/ecd/2026 true true