v3.26.1
Segment Reporting - Schedule of Segment Expenses and Other Segment Items (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Segment Reporting [Line Items]        
Collaboration revenue from a related party $ 13,374 $ 9,626 $ 21,587 $ 19,045
Less:        
Total external program expenses 6,288 8,988 13,211 16,801
Employee and contractor-related expenses [1] 7,713 6,217 14,567 12,431
Facility and other expenses 916 920 2,039 1,744
Total research and development 14,917 16,125 29,817 30,976
General and administrative [1] 4,801 4,594 9,484 9,103
Interest and other income, net (2,487) (895) (4,778) (2,018)
Net loss (3,857) (10,198) (12,936) (19,016)
5366        
Less:        
Total external program expenses 343 3,048 720 4,728
1179        
Less:        
Total external program expenses 839 1,331 2,625 2,065
6250        
Less:        
Total external program expenses [2] 609 1,458 2,098 3,903
HDV        
Less:        
Total external program expenses 480 0 480 0
CLD        
Less:        
Total external program expenses 100 0 100 0
4334        
Less:        
Total external program expenses 0 380 2 806
7272        
Less:        
Total external program expenses 890 898 1,193 1,650
Research and Discovery        
Less:        
Total external program expenses $ 3,027 $ 1,873 $ 5,993 $ 3,649
[1] Includes stock-based compensation expense, see Note 7 - Stock-Based Compensation for further details.
[2] Amounts for 6250 include shared external program expenses supporting both the HDV and CLD indications. External program expenses directly attributable to a specific indication are reflected separately within the applicable HDV and CLD amounts.