| Schedule of Segment Expenses and Other Segment Items |
The following table presents the significant segment expenses and other segment items regularly reviewed by the Company's CODM:
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Three Months Ended June 30, |
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|
Six Months Ended June 30, |
|
|
2026 |
|
|
2025 |
|
|
2026 |
|
|
2025 |
|
Collaboration revenue from a related party |
$ |
13,374 |
|
|
$ |
9,626 |
|
|
$ |
21,587 |
|
|
$ |
19,045 |
|
Less: |
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|
|
|
|
|
|
|
|
|
|
External program expenses: |
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|
|
|
|
|
|
|
|
|
|
5366 |
|
343 |
|
|
|
3,048 |
|
|
|
720 |
|
|
|
4,728 |
|
1179 |
|
839 |
|
|
|
1,331 |
|
|
|
2,625 |
|
|
|
2,065 |
|
6250 (1) |
|
609 |
|
|
|
1,458 |
|
|
|
2,098 |
|
|
|
3,903 |
|
HDV |
|
480 |
|
|
|
— |
|
|
|
480 |
|
|
|
— |
|
CLD |
|
100 |
|
|
|
— |
|
|
|
100 |
|
|
|
— |
|
4334 |
|
— |
|
|
|
380 |
|
|
|
2 |
|
|
|
806 |
|
7272 |
|
890 |
|
|
|
898 |
|
|
|
1,193 |
|
|
|
1,650 |
|
Research and discovery |
|
3,027 |
|
|
|
1,873 |
|
|
|
5,993 |
|
|
|
3,649 |
|
Total external program expenses |
|
6,288 |
|
|
|
8,988 |
|
|
|
13,211 |
|
|
|
16,801 |
|
Employee and contractor-related expenses (2) |
|
7,713 |
|
|
|
6,217 |
|
|
|
14,567 |
|
|
|
12,431 |
|
Facility and other expenses |
|
916 |
|
|
|
920 |
|
|
|
2,039 |
|
|
|
1,744 |
|
Total research and development |
|
14,917 |
|
|
|
16,125 |
|
|
|
29,817 |
|
|
|
30,976 |
|
General and administrative (2) |
|
4,801 |
|
|
|
4,594 |
|
|
|
9,484 |
|
|
|
9,103 |
|
Interest and other income, net |
|
(2,487 |
) |
|
|
(895 |
) |
|
|
(4,778 |
) |
|
|
(2,018 |
) |
Net loss |
$ |
(3,857 |
) |
|
$ |
(10,198 |
) |
|
$ |
(12,936 |
) |
|
$ |
(19,016 |
) |
(1)Amounts for 6250 include shared external program expenses supporting both the HDV and CLD indications. External program expenses directly attributable to a specific indication are reflected separately within the applicable HDV and CLD amounts. (2)Includes stock-based compensation expense, see Note 7 - Stock-Based Compensation for further details.
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