FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person *
STERN ADAM K

(Last) (First) (Middle)
888 C 8TH AVE #530

(Street)
NEW YORK NY 10019

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Matinas BioPharma Holdings, Inc. [ MTNB ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director X 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
10/16/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, par value $0.0001 per share 10/31/2025 (1)   X   92,100 A $ 0.6446 (2) 113,450 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern
Common Stock, par value $0.0001 per share 07/10/2026 (2)   X   344,710 A $ 0.35 (2) 416,900 I Through A.K.S Family Partners LP
Common Stock, par value $0.0001 per share 07/10/2026 (2)   X   630,335 A $ 0.35 (2) 743,785 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern
Common Stock, par value $0.0001 per share               28,260 D  
Common Stock, par value $0.0001 per share               26,500 I Through AKS Family Foundation
Common Stock, par value $0.0001 per share               6,000 I Through Pavillion Capital Partners LLC
Common Stock, par value $0.0001 per share               6,000 I Through Piper Venture Partners LLC
Common Stock, par value $0.0001 per share               1,000 I Through IRA Adam K Stern - Rollover IRA
Common Stock, par value $0.0001 per share               3,000 I Through Stern Aegis Ventures LLC 401k Plan for the Benefit of Adam K Stern
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants to Purchase Common Stock $ 0.6446 10/16/2025   J   800,000   04/08/2025 04/08/2030 Common Stock, par value $0.0001 per share 800,000 $ 0.6446 800,000 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern (1)
Series C Convertible Preferred Stock $ 0.586 10/16/2025   J   265   04/04/2025   (5) Common Stock, par value $0.0001 per share 452,218 $ 0.586 265 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern (1)
Warrants to Purchase Common Stock $ 0.6446 10/31/2025   X     92,100 04/08/2025 04/08/2030 Common Stock, par value $0.0001 per share 92,100 $ 0.6446 630,335 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern (1)
Warrants to Purchase Common Stock $ 0.35 07/10/2026 (2)   X     630,335 04/08/2025 04/08/2030 Common Stock, par value $0.0001 per share 630,335 $ 0.35 0 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern (1)
Warrants to Purchase Common Stock $ 0.35 07/10/2026 (2)   A   630,335     (2)   (2) Common Stock, par value $0.0001 per share 630,335 $ 0.35 630,335 I Through SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern (1)
Warrants to Purchase Common Stock $ 0.35 07/10/2026 (2)   X     344,710 04/08/2025 04/08/2030 Common Stock, par value $0.0001 per share 344,710 $ 0.35 0 I Through A.K.S Family Partners LP (4)
Warrants to Purchase Common Stock $ 0.35 07/10/2026 (2)   A   344,710     (2)   (2) Common Stock, par value $0.0001 per share 344,710 $ 0.35 344,710 I Through A.K.S Family Partners LP (4)
Warrants to Purchase Common Stock $ 0.35 07/10/2026 (3)   J   141,462     (3)   (3) Common Stock, par value $0.0001 per share 141,462 $ 0.35 141,462 D  
Series C Convertible Preferred Stock $ 0.586             04/04/2025   (5) Common Stock, par value $0.0001 per share 172,354   101 I Through AKS Family Partners (4)
Explanation of Responses:
1. On October 16, 2025, SternAegis Ventures, LLC Defined Benefit Plan for the Benefit of Adam K Stern received 800,000 Warrants to purchase Common Stock and 265 shares of Series C Convertible Preferred Stock in connection with a settlement agreement.
2. On July 10, 2026, the Registrant entered into inducement offer letter agreements with certain Reporting Persons, pursuant to which such Reporting Persons agreed to exercise for cash all of their outstanding warrants at the current exercise price of $0.35 per share in consideration for the Registrant's agreement to issue, in a private placement, new unregistered common stock purchase warrants (the "New Warrants"). The Registrant is required to obtain stockholder approval ("Inducement Stockholder Approval") for the issuance of the shares of common stock underlying the New Warrants. The New Warrants will be exercisable beginning on the date Inducement Stockholder Approval is received at an exercise price of $0.35 per share and will expire on the five-year anniversary of the date Inducement Stockholder Approval is received.
3. On July 10, 2026, the Registrant issued warrants to purchase 374,330 shares of Common Stock (the "Solicitation Agent Warrants") to ThinkEquity LLC in connection with a Solicitation Agreement, dated June 25, 2026. The Solicitation Agent Warrants have terms substantially similar to the New Warrants, including with respect to exercise price, expiration and term. ThinkEquity LLC distributed 141,462 Solicitation Agent Warrants to Mr. Stern.
4. On June 10, 2026, Sanitam Parnters LLC ("Sanitam") distributed its holdings in the Registrant's preferred stock and warrants to its members. A.K.S. Family Partners LP received a portion of such distribution. As such Sanitam no longer beneficially owns any securities of the Registrant.
5. The Series C Convertible Preferred Stock of the Registrant is perpetual and has no expiration date.
/s/ Adam K. Stern 08/13/2026
** Signature of Reporting Person Date
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