The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 34,041,978 113,085 SH SOLE 4,792 0 108,293
AVALO THERAPEUTICS INC COM NEW 05338F306 8,660,948 468,666 SH SOLE 19,854 0 448,812
BIONTECH SE SPONSORED ADS 09075V102 70,210,878 754,550 SH SOLE 31,971 0 722,579
GENERATE BIOMEDICINES INC COM SHS 370920100 13,912,335 824,679 SH SOLE 42,524 0 782,155
INSMED INC COM PAR $.01 457669307 59,688,435 559,824 SH SOLE 23,750 0 536,074
IONIS PHARMACEUTICALS INC COM 462222100 63,329,637 798,709 SH SOLE 33,833 0 764,876
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 34,411,155 1,191,522 SH SOLE 50,484 0 1,141,038
MINERALYS THERAPEUTICS INC COM 603170101 23,169,156 858,753 SH SOLE 35,869 0 822,884
NATERA INC COM 632307104 32,295,764 118,975 SH SOLE 4,971 0 114,004
PROCEPT BIOROBOTICS CORP COM 74276L105 10,497,894 464,920 SH SOLE 19,699 0 445,221
REGENERON PHARMACEUTICALS COM 75886F107 57,764,746 92,640 SH SOLE 3,925 0 88,715
ROIVANT SCIENCES LTD SHS G76279101 68,405,473 1,932,904 SH SOLE 82,000 0 1,850,904
ROYALTY PHARMA PLC SHS CLASS A G7709Q104 64,806,211 1,155,809 SH SOLE 48,971 0 1,106,838
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 23,939,987 446,059 SH SOLE 18,632 0 427,427
VERA THERAPEUTICS INC CL A 92337R101 21,404,881 498,832 SH SOLE 21,164 0 477,668