Property and equipment, net consist of the following (in thousands):


	June 30,			December 31,
	2026			2025
Laboratory equipment	$	4,298		$	4,259
Leasehold improvements		1,655			1,655
Office equipment		227			227
Software		104			104
Total property and equipment excluding construction-in-progress		6,284			6,245
Less accumulated depreciation and amortization		(5,853	)		(5,540	)
Property and equipment excluding construction-in-progress, net		431			705
Construction-in-progress		94			31
Total property and equipment, net	$	525		$	736

Depreciation and amortization expense totaled $0.2 million and $0.3 million for the three and six months ended June 30, 2026, respectively. Depreciation and amortization expense totaled $0.2 million and $0.5 million for the three and six months ended June 30, 2025, respectively.

Accrued expenses and other current liabilities consist of the following (in thousands):


	June 30,		December 31,
	2026		2025
Payroll and related costs	$	2,053	$	2,646
Accrued professional fees		667		718
Accrued rent		316		335
Accrued preclinical and clinical trial costs		34		198
Other		67		46
Total accrued expenses and other current liabilities	$	3,137	$	3,943