75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Consolidated Balance Sheets (unaudited)
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75020 - Statement - Condensed Consolidated Balance Sheets (unaudited) (Parenthetical)
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75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited)
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75040 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) 2
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75050 - Statement - Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) (unaudited)
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75060 - Statement - Condensed Consolidated Statements of Cash Flows (unaudited)
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995455 - Disclosure - Nature of the Business and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Fair Value Measurements
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995485 - Disclosure - Property and Equipment, Net
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995495 - Disclosure - Accrued Expenses and Other Current Liabilities
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995505 - Disclosure - Convertible Preferred Stock
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995515 - Disclosure - Stockholders' Equity (Deficit)
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995525 - Disclosure - Stock-Based Compensation
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995535 - Disclosure - Term Loan
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995545 - Disclosure - Simple Agreement for Future Equity
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995555 - Disclosure - Commitments and Contingencies
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995565 - Disclosure - Collaboration Agreements
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995575 - Disclosure - Related Party Transactions
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995585 - Disclosure - Net Loss Per Share
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995595 - Disclosure - Retirement Plan
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995605 - Disclosure - Segment Reporting
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995615 - Disclosure - Subsequent Events
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995625 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995635 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995645 - Disclosure - Fair Value Measurements (Tables)
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995655 - Disclosure - Property and Equipment, Net (Tables)
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995665 - Disclosure - Accrued Expenses and Other Current Liabilities (Tables)
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995675 - Disclosure - Convertible Preferred Stock (Tables)
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995685 - Disclosure - Stockholders' Equity (Deficit) (Tables)
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995695 - Disclosure - Term Loan (Tables)
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995705 - Disclosure - Stock-Based Compensation (Tables)
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995715 - Disclosure - Net Loss Per Share (Tables)
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995725 - Disclosure - Segment Reporting (Tables)
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995735 - Disclosure - Nature of the Business and Basis of Presentation (Additional Information) (Details)
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995745 - Disclosure - Summary of Significant Accounting Policies (Additional Information) (Details)
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995755 - Disclosure - Summary of Significant Accounting Policies - Schedule of Cash and Cash Equivalents (Details)
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995765 - Disclosure - Fair Value Measurements - Schedule of Financial Assets Measured at Fair Value on a Recurring Basis and Indicate the Level of the Fair Value Hierarchy (Details)
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995775 - Disclosure - Fair Value Measurements - Schedule of Gross Unrealized Gains and Losses of Marketable Securities (Details)
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995785 - Disclosure - Fair Value Measurements - Schedule of Changes in the Aggregate Fair Value (Details)
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995795 - Disclosure - Fair Value Measurements (Additional Information) (Details)
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995805 - Disclosure - Property and Equipment, Net - Schedule of Property And Equipment Net (Details)
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995815 - Disclosure - Property and Equipment, Net (Additional Information) (Details)
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995825 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995835 - Disclosure - Collaboration Agreements (Additional Information) (Details)
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995845 - Disclosure - Convertible Preferred Stock (Additional Information) (Details)
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995855 - Disclosure - Convertible Preferred Stock - Summary of the significant Level 3 Unobservable Inputs (Details)
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995865 - Disclosure - Convertible Preferred Stock - Summary of Convertible Preferred Stock Except Share and Per Share Amounts (Details)
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995875 - Disclosure - Convertible Preferred Stock - Convertible Preferred Stock was Converted into Common Stock and Non-Voting Common Stock (Details)
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995885 - Disclosure - Stock-Based Compensation (Additional Information) (Details)
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995895 - Disclosure - Stockholders' Equity (Deficit) (Additional Information) (Details)
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995905 - Disclosure - Stockholders' Equity (Deficit) - Schedule of Reserved Shares of Common Stock for the Conversion or Exercise (Details)
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995915 - Disclosure - Stock-Based Compensation - Schedule of stock option granted using the Black-Scholes option-pricing mode and assumptions (Details)
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995925 - Disclosure - Stock-Based Compensation - Schedule of stock option activity (Details)
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995935 - Disclosure - Stock-Based Compensation - Schedule of Stock-Based Compensation Expense (Details)
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995935 - Disclosure - Stock-Based Compensation - Schedule of Stock-Based Compensation Expense (Details) [Default]
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995945 - Disclosure - Term Loan - Schedule of Term Loan Balances (Details)
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995955 - Disclosure - Term Loan (Additional Information) (Details)
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995965 - Disclosure - Related Party Transactions (Additional Information) (Details)
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995975 - Disclosure - Retirement Plan (Additional Information) (Details)
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995985 - Disclosure - Simple Agreement for Future Equity (Additional Information) (Details)
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995995 - Disclosure - Commitments and Contingencies (Additional Information) (Details)
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996005 - Disclosure - Net Loss Per Share (Additional Information) (Details)
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996015 - Disclosure - Net Loss Per Share - Schedule of Calculation of Diluted Net Loss Per Share Allocable to Common Stockholders (Details)
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996025 - Disclosure - Segment Reporting - Schedule of Financial Information (Details)
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996035 - Disclosure - Segment Reporting (Additional Information) (Details)
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996045 - Disclosure - Subsequent Events (Additional Information) (Details)
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Related Party Transaction [Table]
Contract With Customer Performance Obligation Unsatisfied Or Partially Unsatisfied
Contract With Customer Performance Obligation Unsatisfied Or Partially Unsatisfied
Contract With Customer Performance Obligation Unsatisfied Or Partially Unsatisfied
Proceeds from Sale and Maturity of Marketable Securities
Proceeds from maturities of marketable securities
Convertible Preferred Stock, Shares Issued
Convertible Preferred Stock, Shares Issued upon Conversion
Dividend Income, Operating
Dividend Income, Operating, Total
Dividend Income
Summary of Convertible Preferred Stock Shares Conversation Table Text Block
Summary of Convertible Preferred Stock Shares Conversation Table Text Block
Summary of Convertible Preferred Stock Shares Conversation Table Text Block
Accounts Payable, Total
Accounts Payable
Accounts Payable
Common Stock, Capital Shares Reserved for Future Issuance
Common Stock Shares, Reserved
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Preferred Stock, Shares Issued
Preferred stock, shares issued
Shares of Preferred Stock Issued
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Total unrecognized stock-based compensation cost
Related Party Transaction, Description of Transaction
Unissued Stock-Based Awards Under the 2016 Employee, Director and Consultant Equity Incentive Plan [Member]
Unissued Stock-Based Awards Under the 2016 Employee, Director and Consultant Equity Incentive Plan [Member]
Unissued stock-based awards under the 2016 Employee, Director and Consultant Equity Incentive Plan
Commitments and Contingencies
Commitments and contingencies (Note 11)
Weighted average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Nonvoting Common Stock [Member]
Nonvoting Common Stock [Member]
Minimum [Member]
Minimum [Member]
Private Placement [Member]
Private Placement [Member]
Unrealized Gain (Loss) on Price Risk Fair Value Hedging Instruments
Unrealized loss on aggregate fair value
Preferred Stock, Shares Outstanding
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Shares of Preferred Stock Outstanding
Fair Value, Recurring [Member]
Fair Value, Recurring [Member]
Common Stock, Shares, Issued
Common stock, shares issued
Segment Reporting [Line Items]
Counterparty Name [Domain]
Two Thousand Twenty Six Employee Stock Purchase Plan [Member]
Two Thousand Twenty Six Employee Stock Purchase Plan [Member]
2026 Employee Stock Purchase Plan [Member]
Upfront Payment
Upfront Payment
Upfront payment
Related Party Transaction [Line Items]
estricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs) [Member]
Schedule of Conversions of Stock [Table Text Block]
Schedule of Reserved Shares of Common Stock for the Conversion or Exercise
Summary of Convertible Preferred Stock Except Share and Per Share Amounts
Stock Issued During Period, Value, Conversion of Units
Fair Value of Agreement Upon Conversion
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Debt, Current
Debt, Current, Total
Term loan, net of discount
Term loan, net of discount
Operating Segments [Member]
Intangible Asset, Finite-Lived, Class [Domain]
Preferred Stock, Convertible, Down Round Feature, Increase (Decrease) in Equity, Amount
Deemed dividend upon down-round of convertible preferred stock
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock and non-voting common stock
Line of Credit Facility, Maximum Borrowing Capacity
Line of credit facility maximum borrowing capacity
Subsequent Event Type [Domain]
Property and Equipment, Net
Property, Plant, and Equipment [Text Block]
Reduction Of The Transaction Price
Reduction Of The Transaction Price
Reduction Of The Transaction Price
Total other (expense) income, net
Nonoperating Income (Expense)
Common Stock, Other Shares, Outstanding
Number of Shares
Schedule of Long-Term Debt Instruments [Table]
General and administrative
General and Administrative Expense
General and Administrative Expense, Total
Income Statement [Abstract]
License Agreement [Member]
License Agreement [Member]
Accrued offering costs
Accrued Offering Costs
Accrued Offering Costs
External Research and Development Expense Early Discovery and Other Programs [Member]
External Research and Development Expense Early Discovery and Other Programs
External research and development expense -Early discovery and other programs
Related and Nonrelated Parties [Domain]
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Net loss per share allocable to common stockholders, basic
Document Period End Date
Document Information [Table]
Series B Preferred Stock [Member]
Series B Preferred Stock
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Payments to Acquire Property, Plant, and Equipment, Total
Debt Instrument [Line Items]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted Average Exercise Price per Share, Granted
Common Stock, Shares Authorized
Common stock, shares authorized
Statement of Stockholders' Equity [Abstract]
Finance Lease, Right-of-Use Asset, after Accumulated Amortization
Finance Lease, Right-of-Use Asset, after Accumulated Amortization, Total
Finance lease right-of-use assets
Unissued Stock-Based Awards Under the 2026 Stock Option and Incentive Plan [Member]
Unissued Stock-Based Awards Under the 2026 Stock Option and Incentive Plan [Member]
Unissued stock-based awards under the 2026 Stock Option and Incentive Plan
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Debt Interest rate
Debt Instrument, Interest Rate, Stated Percentage
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Aggregate Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Unamortized Debt Issuance Expense
Unamortized debt discount and issuance costs
Unamortized debt discount and issuance costs
Total assets
Assets
Title of 12(b) Security
Preferred Stock, Value, Issued
Preferred stock
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of stock options
Gain (Loss) on Securities [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule Of Stock-Based Compensation Expense
Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Machinery and Equipment, Gross
Furniture and fixtures
Fair Value Proceeds Received
Fair Value Proceeds Received
Fair Value Proceeds Received
Conversion Of Convertible Preferred Stock Into Common Stock And Non-Voting Common Stock
Conversion Of Convertible Preferred Stock Into Common Stock And Non-Voting Common Stock
Conversion of convertible preferred stock into common stock and non-voting common stock
Proceeds from Issuance of Private Placement
Proceeds from concurrent private placement of common stock
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest
Unissued Stock-Based Awards Under the 2026 Employee Stock Purchase Plan [Member]
Unissued Stock-Based Awards Under the 2026 Employee Stock Purchase Plan [Member]
Unissued stock-based awards under the 2026 Employee Stock Purchase Plan
Proceeds from Issuance of Long-Term Debt
Proceeds from Issuance of Long-Term Debt, Total
Proceeds From Issuance Of Long Term Debt
Debt Instrument, Description
Debt instrument description
External Research and Development Expense Catenin Degrader [Member]
External Research and Development Expense Catenin Degrader
External research and development expense - Catenin Degrader
Cash and Cash Equivalents [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term
Weighted Average Remaining Contractual Term, Outstanding
Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization [Abstract]
Finance Lease, Right-of-Use Asset, Accumulated Amortization
Accumulated amortization expense
Schedule of Segment Information
Segment Reporting [Table Text Block]
Research Collaboration and Option Agreement [Member]
Research Collaboration and Option Agreement [Member]
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Proceeds from Related Party Debt
Total stockholders' equity (deficit)
Equity, Attributable to Parent
Beginning Balance Value
Ending Balance Value
Valuation Approach and Technique [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Marketable Securities, Realized Gain (Loss)
Change in unrealized gains (losses) on marketable securities
Earnings Per Share [Text Block]
Net Loss Per Share
Category of Item Purchased [Axis]
Interest Income, Other
Interest income
Number of Reportable Segments
Stockholders' Equity Note [Abstract]
Convertible Preferred Stock [Abstract]
Change in Fair Value of SAFE at Issuance
Change in Fair Value of SAFE at Issuance
Change in fair value of SAFE
Stock, Class of Stock [Table]
Undesignated Shares [Member]
Undesignated Shares [Member]
Undesignated Shares [Member]
Proceeds from Stock Options Exercised
Proceeds from exercise of stock options
Increase (Decrease) in Due from Related Parties
Increase (Decrease) in Due from Related Parties, Total
Due from related party
Statistical Measurement [Axis]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Comprehensive loss:
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Money Market Funds [Member]
Money market funds
Preferred Stock, No Par Value
convertible preferred stock per share
Entity Interactive Data Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, Maximum
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Intrinsic Values Of Stock Options Exercised During Period
Intrinsic Values Of Stock Options Exercised During Period
Intrinsic values of stock options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term, Vested and expected to vest
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Common Stock, Value, Issued
Common stock
Schedule of Calculation of Diluted Net Loss Per Share Allocable to Common Stockholders
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Convertible Preferred Stock
Preferred Stock [Text Block]
Nature of the Business and Basis of Presentation
Business Description and Basis of Presentation [Text Block]
Total liabilities
Liabilities
Conversion of simple agreement for future equity into common stock, shares
Conversion of simple agreement for future equity into common stock, shares
Schedule of Financial Assets Measured at Fair Value on a Recurring Basis and Indicate the Level of the Fair Value Hierarchy
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Product and Service [Axis]
Retained Earnings (Accumulated Deficit)
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Convertible Preferred Stock [Member]
Convertible Preferred Stock [Member]
Stock Issued During Period, Shares, Other
Issuance of common stock in initial public offering
Fair Value, Inputs, Level 3 [Member]
Level 3
Issuance of common stock in concurrent private placement
Issuance of common stock in concurrent private placement
Operating Expenses
Total operating expenses
Preferred Stock, Convertible, Shares Issuable
Shares of Common Stock Issuable Upon Conversion
Shares of Preferred Stock Issued
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Shares Issued, Price Per Share
Price Per Share
Offering Price
Stock Issued During Period, Shares, New Issues
Stock Issued During Period, Shares, New Issues
Nonvoting Common Stock Shares Authorized
Nonvoting Common Stock Shares Authorized
Nonvoting Common Stock Shares Authorized
Exercise Of Common Warrants Into Common Stock Shares
Exercise Of Common Warrants Into Common Stock Shares
Net exercise of warrants to purchase common stock shares
Initial Public Offering Price Per Share
Initial Public Offering Price Per Share
Initial Public Offering Price Per Share
Series E Preferred Stock [Member]
Series E Preferred Stock
Deferred Compensation Arrangement with Individual, Compensation Expense
Compensation Expense
IPO [Member]
IPO [Member]
Shares Available For Future Issuance
Shares Available For Future Issuance
Shares available for future issuance
Restricted Cash
Restricted Cash, Total
Restricted cash - long-term
Restricted cash
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, Maximum
Collaboration Exclusive License and Research Services Amount
Collaboration Exclusive License and Research Services Amount
Exclusive License and Research Services for Collaboration
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization, Ending Balance
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization, Beginning Balance
Property, Plant, and Equipment, Accumulated Depreciation, Depletion, and Amortization, Total
Less: accumulated depreciation and amortization
Less: accumulated depreciation and amortization
Operating Costs and Expenses
Operating Costs and Expenses, Total
Related Party Transactions [Abstract]
ARTBIO, Inc [Member]
ARTBIO, Inc [Member]
ARTBIO, Inc.
Furniture and Fixtures, Gross
Computer equipment
Subsequent Events
Subsequent Events [Text Block]
Long-Term Debt [Text Block]
Term Loan
Other General and Administrative Expense
Other general and administrative expenses
Fair Value Hierarchy and NAV [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Cumulative Dividends On Convertible Preferred Stock
Cumulative Dividends On Convertible Preferred Stock
Cumulative dividends on convertible preferred stock
Cumulative dividends on convertible preferred stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Common Unit, Issuance Value
Fair Value of Agreement
Payments of convertible preferred stock issuance costs
Payments of Stock Issuance Costs
Stock issuance cost
Target Two [Member]
Target Two [Member]
Target 2
Operating Lease, Liability, Current
Operating lease liabilities, current portion
Other Liabilities Disclosure [Abstract]
Total liabilities, convertible preferred stock and stockolders ' equity (deficit)
Liabilities and Equity
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Research and Development Expense
Research and Development Expense, Total
Research and development cost
Conversion of SAFE Into Common Stock
Conversion of SAFE Into Common Stock
Conversion of SAFE into common stock
Intangible Asset, Finite-Lived, Class [Axis]
Document Fiscal Period Focus
Transaction price of performance obligations
Revenue, Remaining Performance Obligation, Amount
Short-Term Debt
Short-Term Debt, Total
Total term loan principal
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of stock option granted using the Black-Scholes option-pricing mode and assumptions
Summary the Significant Level 3 Unobservable Inputs
Revenue Recognition, Allowances [Policy Text Block]
Revenue Recognition
Depreciation, Depletion and Amortization, Nonproduction
Depreciation and amortization expense
Depreciation, Depletion and Amortization, Nonproduction, Total
Gross Proceeds
Proceeds from Other Equity
Development Milestone Payments
Development Milestone Payments
Development milestone payments
Two Thousand Twenty Six Stock Option And Grant Plan [Member]
Two Thousand Twenty Six Stock Option And Grant Plan [Member]
2026 Stock Option and Grant Plan [Member]
Marketable Security, Gain (Loss) [Abstract]
Sale of Stock [Axis]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Increase in cash, cash equivalents and restricted cash
Entity Current Reporting Status
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Vested and exercisable
Simple Agreement for Future Equity [Text Block]
The entire disclosure for for Future Equity
Simple Agreement for Future Equity
Deferred Revenue
Deferred Revenue, Total
Deferred revenue
Fair Value, Inputs, Level 1 [Member]
Level 1
Class of Stock [Domain]
Accounts Payable, Current
Accounts Payable, Current, Total
Accounts payable
Series E Convertible Preferred Stock [Member]
Series E Convertible Preferred Stock [Member]
Series E Preferred Convertible Stock [Member]
Financial Instrument [Axis]
Change in fair value of simple agreement for future equity
Change In Fair Value Of Simple Agreement For Future Equity
Change In Fair Value Of Simple Agreement For Future Equity
Change in fair value of simple agreement for future equity
Change in fair value of simple agreement for future equity
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment and Tax
Change in unrealized gains (losses) on marketable securities
Document Transition Report
Grant-date fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Grant Date Intrinsic Value
Commitments and Contingencies Disclosure [Abstract]
Subsequent Event [Line Items]
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Accounts payable, accrued expenses and other liabilities
Voting Common Stock [Member]
Voting Common Stock Member
Liabilities, Current [Abstract]
Current liabilities:
Research Collaboration Agreement with ARTBIO, Inc.
Research Collaboration Agreement with ARTBIO, Inc. [Member]
Research Collaboration Agreement with ARTBIO, Inc. [Member]
Share-Based Payment Arrangement [Abstract]
Conversion of Stock, Shares Converted
Converted shares
Target One [Member]
Target One [Member]
Target 1
Common Stock Warrants [Member]
Common Stock Warrants [Member]
Common Stock Warrants
Common Stock [Member]
Common Stock [Member]
Convertible Preferred Shares [Member]
Convertible Preferred Shares [Member]
Convertible Preferred Stock [Member]
Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Line Items]
Statistical Measurement [Domain]
Marketable Securities
Marketable Securities, Total
Marketable Securities
Nonoperating Income (Expense) [Abstract]
Other income (expense):
Increase and Decrease in Research and Development Expenses
Increase and Decrease in Research and Development Expenses
Reduction of research and development expenses
Proceeds From Issuance Of Simple Agreement For Future Equity
Proceeds From Issuance Of Simple Agreement For Future Equity
Proceeds from issuance of simple agreement for future equity
Weighted average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Property, Plant, and Equipment [Abstract]
Assets
Assets [Abstract]
Entity Central Index Key
Non-Voting Common Stock, Value
Non-Voting Common Stock, Value
Non-Voting Common Stock, Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value, Vested and exercisable
Class of Stock [Line Items]
Deferred Income, Revenue Recognized
Company recognized revenue
Consolidation Items [Axis]
Current Fiscal Year End Date
Document Quarterly Report
Earnings Per Share, Diluted, by Common Class, Including Two-Class Method [Table]
Term loan maturity date
Debt Instrument, Maturity Date
Stock Issued During Period, Value, Other
Issuance of common stock in initial public offering, Value
Cash and Cash Equivalents [Axis]
Fair Value, Inputs, Level 2 [Member]
Level 2
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price per Share, Outstanding, Beginning Balance
Weighted Average Exercise Price per Share, Outstanding, Ending Balance
Material legal proceedings
Material Legal Proceedings
Material Legal Proceedings
Change in unrealized gains (losses) on marketable securities
Change in unrealized gains (losses) on marketable securities
Change in unrealized gains (losses) on marketable securities
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Entity Incorporation, State or Country Code
Simple Agreement for Future Equity [Member]
Simple Agreement for Future Equity [Member]
Simple Agreement for Future Equity [Member]
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Net loss per share allocable to common stockholders, diluted
Outstanding stock options
Outstanding Stock Options [Member]
Outstanding Stock Options [Member]
Sale of Stock, Number of Shares Issued in Transaction
Number of share issued and sold
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Price per share
Net loss
Net loss
Granted fair value adjustment
Fair Value Adjustment of Warrants
Stock based compensation expense
Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture
Shares Issued, Value, Share-Based Payment Arrangement, after Forfeiture, Total
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Indemnification Agreements [Member]
Indemnification Agreements [Member]
Indemnification Agreements [Member]
Target Four [Member]
Target Four [Member]
Tagret 4
Assets not yet in service
Assets Not Yet in Service Gross
Assets Not Yet in Service Gross
Preferred stock, liquidation preference value
Preferred Stock, Liquidation Preference, Value
Liquidation Preference
Measurement Frequency [Domain]
Equity Components [Axis]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities
Payments to Acquire in Process Research and Development
Payments to achievement of certain development
Collaborative Arrangement Disclosure [Text Block]
Collaboration Agreements
Statement of Cash Flows [Abstract]
Employee Benefits and Share-Based Compensation
Stock-based compensation expense
Fair Value Hierarchy and NAV [Domain]
Stockholders' Equity, Reverse Stock Split
Reverse stock split
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price per Share, Exercised
Weighted average grant date fair value per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Retirement Benefits [Abstract]
Line of Credit Facility, Commitment Fee Percentage
Line of credit description
Deferred Offering Costs
Deferred offering costs
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other assets
Fair Value Disclosures [Text Block]
Fair Value Measurements
Restricted Cash and Cash Equivalent
Total cash, cash equivalents and restricted cash
External research and development expense ERG [Member]
External research and development expense ERG
External research and development expense ERG
Finance Lease, Liability, Noncurrent
Finance lease liabilities, net of current portion
Payments of initial public offering costs
Payments for Repurchase of Initial Public Offering
Depreciation and amortization
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Shares of Preferred Stock Authorized
Long-Term Purchase Commitment, Category of Item Purchased [Domain]
Class of Stock [Axis]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Counterparty Name [Axis]
Number Of Shares Of Common Stock Contingent
Number Of Shares Of Common Stock Contingent
Shares of common stock contingent
Number of Operating Segments
Series C Preferred Stock [Member]
Series C Preferred Stock
AOCI Attributable to Parent [Member]
Deferred revenue
Increase (Decrease) in Deferred Revenue
Unrealized Gains
Marketable Securities Unrealized Gains
Marketable Securities Unrealized Gains
Deferred Charges, Policy [Policy Text Block]
Deferred Offering Costs
Percenatge of Outstanding Principal Amount
Percenatge of Outstanding Principal Amount
Percenatge of outstanding principal amount
Proceeds from Issuance Initial Public Offering
Proceeds from initial public offering, net of underwriting discounts and commissions
Segment Reporting, Policy [Policy Text Block]
Segment Information
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted Average Exercise Price per Share, Cancel or forfeited
Personnel-Related General and Administrative Expenses [Member]
Personnel-Related General and Administrative Expenses [Member]
Personnel-related general and administrative expenses (excluding stock-based compensation expense)
Other Research and Development Expense
Other research and development expenses
Accrued Liabilities, Current
Accrued expenses and other current liabilities
Total
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Shares, Outstanding, Beginning Balance
Number of Shares, Outstanding, Ending Balance
Term loan, net of discount
Long-Term Debt, Current Maturities
Long-Term Debt, Current Maturities, Total
Short-Term Debt [Line Items]
NAV Per Share
Net asset value per share
Document Type
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities
Liabilities and Equity [Abstract]
Liabilities, convertible preferred stock and stockholders' equity (deficit)
Subsequent Event [Member]
Operating Income (Loss)
Loss from operations
Replacement Collaboration Target Second
Replacement Collaboration Target Second
Second Replacement Collaboration Target
Sale of stock price per share
Sale of Stock, Price Per Share
Original Issuance Price Per Share
Segment Reporting [Table]
Securities Act File Number
Legal Proceedings [Member]
Legal Proceedings [Member]
Legal Proceedings [Member]
Laboratory equipment
Laboratory Equipment Gross
Laboratory Equipment Gross
Location, Statement of Income, Balance [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, Minimum
Retained Earnings [Member]
Convertible Preferred Stock [Table Text Block]
Convertible Preferred Stock Table Text Block
Schedule Convertible Preferred Stock was Converted into Common Stock and Non-Voting Common Stock
Settlement Of Series E Preferred Stock Tranche Right Liability
Settlement Of Series E Preferred Stock Tranche Right Liability
Settlement of Series E preferred stock tranche right liability
Settlement of Series E preferred stock tranche right liability
Entity Registrant Name
Accounting Policies [Abstract]
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Initial Public Offering Costs Included In Accounts Payable And Accrued Expenses
Initial Public Offering Costs Included In Accounts Payable And Accrued Expenses
Initial public offering costs included in accounts payable and accrued expenses
Amortized Cost
Debt Securities, Trading, Amortized Cost
Percentage of Related Party to Sublease
Percentage of Related Party to Sublease
Entity Address, Address Line One
Accrued Expenses and Other Current Liabilities
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Number of shares option to purchase
Incremental Common Shares Attributable to Dilutive Effect of Equity Unit Purchase Agreements
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercised
Issuance of common stock upon exercise of stock options shares
Vested and exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Total current assets
Assets, Current
Fair Value, Recurring and Nonrecurring [Table]
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share
Increase (Decrease) in Operating Liabilities
Increase (Decrease) in Operating Liabilities
Increase (Decrease) in Operating Liabilities, Total
Supplemental Cash Flow Information [Abstract]
Supplemental disclosure of cash flow information:
First Replacement Collaboration Target
Replacement Collaboration Target First
Replacement Collaboration Target First
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Contractual Purchase Price
Contractual Purchase Price
Contractual Purchase Price
Entity Small Business
Long Term Debt Noncurrent
Long-Term Debt, Excluding Current Maturities
Long-Term Debt, Excluding Current Maturities, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate Intrinsic Value, Vested and expected to vest
2026 Stock Option and Incentive Plan [Member]
Two Thousand Twenty Six Stock Option And Incentive Plan [Member]
Two Thousand Twenty Six Stock Option And Incentive Plan [Member]
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Total unrecognized compensation expense related to unvested stock options
Conversion of Stock, Amount Issued
Common stock issued upon conversion
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Long-Term Debt and Lease Obligation, Current
Long-Term Debt and Lease Obligation, Current, Total
Final payments
Consolidation Items [Domain]
Other Assets
Other Assets, Total
Other assets
Schedule of Term Loan Balances
Schedule of Long-Term Debt Instruments [Table Text Block]
Shares Increment
Shares Increment
Shares increase
Earnings Per Share [Abstract]
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Schedule of stock option award
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Schedule of stock option activity
Rent receivable - related party
Rent Receivable - Related Party
Rent Receivable - Related Party
Sale of Stock, Consideration Received Per Transaction
Gross proceeds
Plan Name [Axis]
Subsequent Event Type [Axis]
Equity [Abstract]
Product and Service [Domain]
Stock Compensation Plan [Member]
Share-Based Payment Arrangement [Member]
Equity [Text Block]
Stockholders' Equity (Deficit)
Measurement Frequency [Axis]
Cash flows from financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Equity Conversion Rate
Equity Conversion Rate
Equity conversion rate
Entity Incorporation, Date of Incorporation
Incorporation date
Non-Cash Interest Expense
Non-Cash Interest Expense
Non-cash interest expense
Entity Tax Identification Number
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock and non-voting common stock
Schedule of Changes in the Aggregate Fair Value [Table Text Block]
Schedule of Changes in the Aggregate Fair Value [Table Text Block]
Schedule of Changes in the Aggregate Fair Value
Debt Instrument, Interest Rate, Basis for Effective Rate
Effective interest rate of the term loan
Valuation Approach and Technique [Axis]
Discount Price
Initial Public Offering Discount Price
Initial Public Offering Discount Price
Equity Component [Domain]
Convertible preferred stock
Convertible Preferred Stock, Nonredeemable or Redeemable, Issuer Option, Value
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest
Comprehensive loss
Entity Address, City or Town
Business Combination [Axis]
Capital Expenditures Incurred but Not yet Paid
Purchases of property and equipment included in accounts payable
Stock Issued During Period, Value, New Issues
Entity Common Stock, Shares Outstanding
Non-cash lease expense
Non-Cash Lease Expense
Non-Cash Lease Expense
Public offering price per share
Public Offering Price Per Share
Public Offering Price Per Share
License and Collaboration Agreement with Regeneron [Member]
License and Collaboration Agreement with Regeneron [Member]
License and Collaboration Agreement with Regeneron
Long-Term Purchase Commitment, Milestones
Long-Term Purchase Commitment, Milestones
Discount Price Per Share
Discount Price Per Share
Discount Price Per Share
Payments to Acquire Marketable Securities
Purchases of marketable securities
Statement [Table]
Deferred revenue, current portion
Deferred Revenue, Current
Deferred Revenue, Current, Total
Deferred Offering Costs [Policy Text Block]
Deferred Offering Costs [Policy Text Block]
Deferred Offering Costs
Share-Based Payment Arrangement, Expense
Stock-Based Compensation Expense
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest, Total
Consolidated net loss
Entity Shell Company
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash (used in) provided by investing activities
Valuation, Market Approach [Member]
Valuation, Market Approach [Member]
Statement [Line Items]
Common Stock, Conversion Basis
Common Stock, Conversion Basis
Deferred Revenue, Noncurrent
Deferred Revenue, Noncurrent, Total
Deferred revenue, net of current portion
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Maximum [Member]
Maximum [Member]
Debt Disclosure [Abstract]
Conversion Of Simple Agreement For Future Equity Into Common Stock
Conversion Of Simple Agreement For Future Equity Into Common Stock
Conversion of simple agreement for future equity into common stock
Sale of Stock [Domain]
Business Combination [Domain]
Target Three [Member]
Target Three [Member]
Target 3
Subsequent Events [Abstract]
Forward contract
Forward contract
Two Thousand Sixteen Employee Director And Consultant Equity Incentive Plan [Member]
Two Thousand Sixteen Employee Director And Consultant Equity Incentive Plan [Member]
2016 Plan [Member]
Assets, Current [Abstract]
Current assets:
Finance lease liabilities, current portion
Finance Lease, Liability, Current
Document Fiscal Year Focus
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of discounts on marketable securities
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Private Placement Price Per Share
Private Placement Price Per Share
Private Placement Price Per Share
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Accrued Liabilities
Accrued Liabilities, Total
Accrued Liabilities
Financial Instruments [Domain]
Commissions and offering costs
Payments for Commissions
Incremental Common Shares Attributable to Dilutive Effect of Contingently Issuable Shares
Incremental Common Shares Attributable to Dilutive Effect of Contingently Issuable Shares
Summary of the significant Level 3 Unobservable Inputs
Summary of the significant Level 3 Unobservable Inputs [Table Text Block]
Tabular disclosure of significant Level 3 unobservable inputs used to estimate the fair value of the Series A Preferred Stock
Related Party [Member]
Related Party [Member]
Entity Ex Transition Period
Amount Of Achieved Milestones
Amount Of Achieved Milestones
Achieved milestones
Contract with Customer, Performance Obligation Satisfied in Previous Period
Contract With Customer Performance Obligation Satisfied In Previous Period
Issuance of common stock in concurrent private placement,Shares
Issuance of common stock in concurrent private placement,Shares
Operating Lease, Liability, Noncurrent
Operating lease liabilities, net of current portion
Net Proceeds From Stock Issuance
Net Proceeds From Stock Issuance
Net Proceeds From Stock Issuance
Other Accrued Liabilities, Current
Other
Accrued expenses and other current liabilities
Security Exchange Name
Revenues
Revenues, Total
Collaboration revenue
Related and Nonrelated Parties [Axis]
Series D Preferred Stock [Member]
Series D Preferred Stock
Recently Issued Accounting Pronouncements Not Yet Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Class of Warrant or Right, Exercise Price of Warrants or Rights
Class of Warrant or Right, Exercise Price of Warrants or Rights
Purchases Of Property And Equipment Included In Accounts Payable
Purchases Of Property And Equipment Included In Accounts Payable
Purchases of property and equipment included in accounts payable
Entity Address, State or Province
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Recognize compensation over a weighted-average period
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, Minimum
Commitments, Fair Value Disclosure
Commitment at fair value
Series A Preferred Stock [Member]
Series A Preferred Stock
Debt Instrument, Covenant Description
Non-Voting Common Stock [Member]
Non-Voting Common Stock [Member]
Non-Voting Common Stock [Member]
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Series F Convertible Preferred Stock [Member]
Series F Convertible Preferred Stock [Member]
Series F Convertible Preferred Stock [Member]
Amendment Flag
Share-Based Payment Arrangement [Text Block]
Stock-Based Compensation
External research and development expense -Zolucatetide
External Research and Development Expense Zolucatetide [Member]
External Research and Development Expense Zolucatetide
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Sublease Income
Sublease income - related party
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation, Total
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
City Area Code
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense
Interest expense
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Proceeds from Issuance of Common Stock
Proceeds From Issuance of Common Stock
Net proceeds
Schedule of Gross Unrealized Gains and Losses of Marketable Securities
Unrealized Gain (Loss) on Investments [Table Text Block]
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Operating Expenses [Abstract]
Operating expenses:
Conversion of Stock, Amount Converted
Conversion of convertible preferred stock into common stock and non-voting common stock
Transaction [Domain]
Long-Term Purchase Commitment [Line Items]
Commercial Milestone Payments
Commercial Milestone Payments
Commercial milestone payments
Deferred Costs, Current
Deferred Costs, Current, Total
Deferred Costs Current
Accrued Employee Benefits, Current
Accrued employee compensation and benefits
Other Liabilities
Other Liabilities, Total
Other liabilities
Retirement Benefits [Text Block]
Retirement Plan
Common Stock, Par or Stated Value Per Share
Common stock, par value
Cash and Cash Equivalents [Abstract]
Cash equivalents:
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term
Weighted Average Remaining Contractual Term, Vested and exercisable
Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Total current liabilities
Liabilities, Current
Current liability
Property and equipment
Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization
Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization, Ending Balance
Property, Plant, and Equipment, before Accumulated Depreciation, Depletion, and Amortization, Beginning Balance
Regulatory Milestone Payments
Regulatory Milestone Payments
Regulatory milestone payments
Entitled to Receive Payment Upon Liquidation
Entitled to Receive Payment
Entitled to Receive Payment
Target 5
Target Five [Member]
Target Five [Member]
Segment Reporting [Text Block]
Segment Reporting
Defined Contribution Plan, Cost
Matching contributions amount
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Trading Symbol
Finance Lease, Right-of-Use Asset, Amortization
Finance lease right-of-use asset amortization
Property, Plant, and Equipment [Table Text Block]
Schedule of Property And Equipment Net
Carrying Value
Increase in Carrying Amount of Redeemable Preferred Stock
Proceeds from Issuance of Convertible Preferred Stock
Proceeds from issuance of convertible preferred stock
Revenue from Contract with Customer, Including Assessed Tax
Collaboration revenue
Subsequent Event [Table]
Entity Emerging Growth Company
Additional Paid-in Capital [Member]
Schedule of Auction Market Preferred Securities by Stock Series [Table Text Block]
Summary of Convertible Preferred Stock Except Share and Per Share Amounts
Aggregate term loan
Long-Term Debt, Gross
Plan Name [Domain]
Fair Value of SAFE at Issuance
Fair Value of SAFE at Issuance
Fair value of SAFE at issuance
U.S. Treasury bills
US Treasury Securities [Member]
Intrinsic value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Leasehold improvements
Leasehold Improvements, Gross
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities:
Cover [Abstract]
Schedule of Cash and Cash Equivalents [Table Text Block]
Schedule of Cash and Cash Equivalents
Segment Reporting, Other Segment Item, Amount
Other segment items
Schedule of Gain (Loss) on Securities [Table]
Stock Option Valuation [Member]
Stock Option Valuation [Member]
Stock Option Valuation [Member]
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive loss
Concentration of Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Share-Based Payment Arrangement, Noncash Expense
Share-Based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Marketable Securities Unrealized Losses
Marketable Securities Unrealized Losses
Unrealized Losses
Additional Paid in Capital
Additional Paid in Capital, Total
Additional paid-in capital
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Fair Value Disclosures [Abstract]
Cash and Cash Equivalent
Cash and Cash Equivalent, Total
Cash and cash equivalents
Personnel Related Research and Development Expenses [Member]
Personnel Related Research and Development Expenses [Member]
Personnel-related research and development expenses
Series F Preferred Stock [Member]
Series F Preferred Stock [Member]
Payments of Debt Issuance Costs
Principal payments on debt
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Fair Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Fair Value
Fair value of common stock
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Balance Beginning
Ending Balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Beginning Balance
Accrued Research And Development Expenses
Accrued Research And Development Expenses
Accrued research and development expenses
Net Income (Loss) Available to Common Stockholders, Basic
Net loss allocable to common stockholders
Net loss allocable to common stockholders
Canceled or forfeited
Canceled or forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Entity Filer Category
Long-Term Purchase Commitment [Table]
Description of Segment
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Marketable Securities, Current
Marketable securities
Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Share Price Per Share, Percentage
Share Price Per Share, Percentage
Share price percentage
Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization
Property and equipment, net
Property and equipment, net
External research and development expense ARON [Member]
External research and development expense ARON
External research and development expense ARON
Ending Balance Shares
Shares, Outstanding
Beginning Balance Shares
Transaction Type [Axis]
Harvard Agreement [Member]
Harvard Agreement [Member]
Harvard Agreement [Member]
Non Voting Shares [Member]
Non Voting Shares [Member]
Non Voting Shares [Member]
Document Information [Line Items]
Segment Reporting [Abstract]
Business Combination, Contingent Consideration, Description
Equity Agreement Description
Conversion of simple agreement for future equity into common stock, value
Conversion of simple agreement for future equity into common stock, value
Entity Address, Postal Zip Code
Statement of Financial Position [Abstract]
Finance Lease, Principal Payments
Principal payments on finance leases
Local Phone Number