<?xml version="1.0" ?><inf:proxyVoteTable xmlns:inf="http://www.sec.gov/edgar/document/npxproxy/informationtable"><inf:proxyTable><inf:issuerName>McKesson Corporation</inf:issuerName><inf:cusip>58155Q103</inf:cusip><inf:isin>US58155Q1031</inf:isin><inf:meetingDate>07/30/2025</inf:meetingDate><inf:voteDescription>Advisory Vote to Approve the Company's Executive Compensation</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>97498.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>97498.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Verona Pharma Plc</inf:issuerName><inf:cusip>925050106</inf:cusip><inf:isin>US9250501064</inf:isin><inf:meetingDate>09/24/2025</inf:meetingDate><inf:voteDescription>To approve, on an advisory, non-binding basis, the compensation that may be paid or become payable to the Company's named executive officers in connection with the Transaction, as disclosed in the table entitled "Potential Payments to Named Executive Officers" beginning on page 70 of the proxy statement, including the associated narrative discussion, and the agreements or understandings pursuant to which such compensation may be paid or become payable.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY 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VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>130742.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>130742.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>The Cooper Companies, Inc.</inf:issuerName><inf:cusip>216648501</inf:cusip><inf:isin>US2166485019</inf:isin><inf:meetingDate>04/07/2026</inf:meetingDate><inf:voteDescription>Approve, on a non-binding, advisory basis, the compensation of our Named Executive Officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY 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VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>544815.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>544815.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Penumbra, Inc.</inf:issuerName><inf:cusip>70975L107</inf:cusip><inf:isin>US70975L1070</inf:isin><inf:meetingDate>05/06/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation that Penumbra's named executive officers will or may be eligible to receive in connection with the Merger; and</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY 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VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>15888.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>15888.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Edwards Lifesciences Corporation</inf:issuerName><inf:cusip>28176E108</inf:cusip><inf:isin>US28176E1082</inf:isin><inf:meetingDate>05/07/2026</inf:meetingDate><inf:voteDescription>Advisory Vote to Approve Named Executive Officer Compensation</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>224128.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>224128.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Abivax SA</inf:issuerName><inf:cusip>00370M103</inf:cusip><inf:isin>US00370M1036</inf:isin><inf:meetingDate>05/11/2026</inf:meetingDate><inf:voteDescription>Approve Compensation of Sylvie Gregoire, Chairwoman of the Board</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>22988.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>22988.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Abivax SA</inf:issuerName><inf:cusip>00370M103</inf:cusip><inf:isin>US00370M1036</inf:isin><inf:meetingDate>05/11/2026</inf:meetingDate><inf:voteDescription>Approve Compensation of Marc de Garidel, CEO</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>22988.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>22988.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Centene Corporation</inf:issuerName><inf:cusip>15135B101</inf:cusip><inf:isin>US15135B1017</inf:isin><inf:meetingDate>05/12/2026</inf:meetingDate><inf:voteDescription>ADVISORY VOTE TO APPROVE EXECUTIVE COMPENSATION.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>228095.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>228095.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Personalis, Inc.</inf:issuerName><inf:cusip>71535D106</inf:cusip><inf:isin>US71535D1063</inf:isin><inf:meetingDate>05/12/2026</inf:meetingDate><inf:voteDescription>Approval, on a non-binding, advisory basis, of the compensation of the Company's named executive officers, as disclosed in the proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>758938.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>758938.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Indivior Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>45579U109</inf:cusip><inf:isin>US45579U1097</inf:isin><inf:meetingDate>05/13/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>123219.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>123219.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Indivior Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>45579U109</inf:cusip><inf:isin>US45579U1097</inf:isin><inf:meetingDate>05/13/2026</inf:meetingDate><inf:voteDescription>To indicate, on an advisory basis, the preferred frequency of shareholder advisory votes on the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>123219.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ONE YEAR</inf:howVoted><inf:sharesVoted>123219.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Viking Therapeutics, Inc.</inf:issuerName><inf:cusip>92686J106</inf:cusip><inf:isin>US92686J1060</inf:isin><inf:meetingDate>05/19/2026</inf:meetingDate><inf:voteDescription>TO APPROVE, ON AN ADVISORY BASIS, THE COMPENSATION OF THE COMPANY'S NAMED EXECUTIVE OFFICERS.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>15858.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>15858.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Align Technology, Inc.</inf:issuerName><inf:cusip>016255101</inf:cusip><inf:isin>US0162551016</inf:isin><inf:meetingDate>05/20/2026</inf:meetingDate><inf:voteDescription>Advisory Vote to Approve the Compensation of our Named Executive Officers</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>7919.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>7919.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Integer Holdings Corporation</inf:issuerName><inf:cusip>45826H109</inf:cusip><inf:isin>US45826H1095</inf:isin><inf:meetingDate>05/20/2026</inf:meetingDate><inf:voteDescription>To approve, in an advisory non-binding vote, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY 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VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>792.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>792.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>NeoGenomics, Inc.</inf:issuerName><inf:cusip>64049M209</inf:cusip><inf:isin>US64049M2098</inf:isin><inf:meetingDate>05/21/2026</inf:meetingDate><inf:voteDescription>Approval, on a non-binding advisory basis, of the Compensation Paid to the Company's Named Executive Officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1542566.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1542566.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Vera Therapeutics, Inc.</inf:issuerName><inf:cusip>92337R101</inf:cusip><inf:isin>US92337R1014</inf:isin><inf:meetingDate>05/21/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the Proxy Statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>77502.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>77502.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Waters Corporation</inf:issuerName><inf:cusip>941848103</inf:cusip><inf:isin>US9418481035</inf:isin><inf:meetingDate>05/21/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>11.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Compass Pathways Plc</inf:issuerName><inf:cusip>20451W101</inf:cusip><inf:isin>US20451W1018</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of the Company's named executive officers for the year ended 31 December 2025</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>1183259.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>1183259.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>DexCom, Inc.</inf:issuerName><inf:cusip>252131107</inf:cusip><inf:isin>US2521311074</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>To provide a non-binding advisory vote on the compensation of our named executive officers for the fiscal year ended December 31, 2025.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>129610.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>129610.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Neurocrine Biosciences, Inc.</inf:issuerName><inf:cusip>64125C109</inf:cusip><inf:isin>US64125C1099</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>Advisory vote on the compensation paid to the Company's named executive officers;</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>201348.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>201348.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Tenet Healthcare Corporation</inf:issuerName><inf:cusip>88033G407</inf:cusip><inf:isin>US88033G4073</inf:isin><inf:meetingDate>05/27/2026</inf:meetingDate><inf:voteDescription>To vote, on an advisory basis, to approve the Company's executive compensation.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>395457.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>395457.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Glaukos Corporation</inf:issuerName><inf:cusip>377322102</inf:cusip><inf:isin>US3773221029</inf:isin><inf:meetingDate>05/28/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory basis, of the compensation of the Company's named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>178556.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>178556.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>UnitedHealth Group Incorporated</inf:issuerName><inf:cusip>91324P102</inf:cusip><inf:isin>US91324P1021</inf:isin><inf:meetingDate>06/01/2026</inf:meetingDate><inf:voteDescription>Advisory approval of the Company's executive compensation.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>50115.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>50115.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Kodiak Sciences Inc.</inf:issuerName><inf:cusip>50015M109</inf:cusip><inf:isin>US50015M1099</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>Approve, on an advisory basis, the compensation of Kodiak's named executive officers, as disclosed in the proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>84053.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>84053.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Oruka Therapeutics, Inc.</inf:issuerName><inf:cusip>687604108</inf:cusip><inf:isin>US6876041087</inf:isin><inf:meetingDate>06/02/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>161958.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>161958.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Globus Medical, Inc.</inf:issuerName><inf:cusip>379577208</inf:cusip><inf:isin>US3795772082</inf:isin><inf:meetingDate>06/03/2026</inf:meetingDate><inf:voteDescription>Approval, on a non-binding, advisory basis, of the 2025 compensation of the company's named executive officers (the "Say-on-Pay" Vote).</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>70150.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>70150.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Alignment Healthcare, Inc.</inf:issuerName><inf:cusip>01625V104</inf:cusip><inf:isin>US01625V1044</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>Approval, on an non-binding, advisory basis, of the compensation of our Named Executive Officers</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>18055.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>18055.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Amylyx Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>03237H101</inf:cusip><inf:isin>US03237H1014</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>6356.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>6356.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Capricor Therapeutics, Inc.</inf:issuerName><inf:cusip>14070B309</inf:cusip><inf:isin>US14070B3096</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>APPROVAL OF NAMED EXECUTIVE OFFICER COMPENSATION, ON A NON-BINDING ADVISORY BASIS</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11733.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>11733.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Capricor Therapeutics, Inc.</inf:issuerName><inf:cusip>14070B309</inf:cusip><inf:isin>US14070B3096</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>APPROVAL OF FREQUENCY OF FUTURE NON-BINDING ADVISORY VOTES ON NAMED EXECUTIVE OFFICER COMPENSATION, ONA NON-BINDING ADVISORY BASIS</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>11733.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ONE YEAR</inf:howVoted><inf:sharesVoted>11733.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>CG Oncology, Inc.</inf:issuerName><inf:cusip>156944100</inf:cusip><inf:isin>US1569441009</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's Named Executive Officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>298.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>298.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>CG Oncology, Inc.</inf:issuerName><inf:cusip>156944100</inf:cusip><inf:isin>US1569441009</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To indicate, on an advisory basis, the preferred frequency of stockholder advisory votes on the compensation of the Company's Named Executive Officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>298.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ONE YEAR</inf:howVoted><inf:sharesVoted>298.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Outset Medical, Inc.</inf:issuerName><inf:cusip>690145206</inf:cusip><inf:isin>US6901452069</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding basis, the 2025 compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>523333.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>AGAINST</inf:howVoted><inf:sharesVoted>523333.000000</inf:sharesVoted><inf:managementRecommendation>AGAINST</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Tango Therapeutics, Inc.</inf:issuerName><inf:cusip>87583X109</inf:cusip><inf:isin>US87583X1090</inf:isin><inf:meetingDate>06/04/2026</inf:meetingDate><inf:voteDescription>To approve, on a non-binding, advisory basis, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>351308.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>351308.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Axsome Therapeutics, Inc.</inf:issuerName><inf:cusip>05464T104</inf:cusip><inf:isin>US05464T1043</inf:isin><inf:meetingDate>06/05/2026</inf:meetingDate><inf:voteDescription>To approve, by non-binding advisory vote, the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>2617.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>2617.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Tectonic Therapeutic, Inc.</inf:issuerName><inf:cusip>878972108</inf:cusip><inf:isin>US8789721086</inf:isin><inf:meetingDate>06/08/2026</inf:meetingDate><inf:voteDescription>Advisory approval of the compensation of the Company's Named Executive Officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>8887.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>8887.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Praxis Precision Medicines, Inc.</inf:issuerName><inf:cusip>74006W207</inf:cusip><inf:isin>US74006W2070</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the compensation of the named executive officers as disclosed in the Company's proxy statement for the 2026 Annual Meeting of Stockholders pursuant to the applicable compensation disclosure rules of the SEC, including the compensation tables and narrative discussion.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>28969.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>28969.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Syndax Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>87164F105</inf:cusip><inf:isin>US87164F1057</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the 2026 proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>212687.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>212687.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>uniQure N.V.</inf:issuerName><inf:cusip>N90064101</inf:cusip><inf:isin>NL0010696654</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory basis, of the compensation of the named executive officers of the Company.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>12129.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>12129.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>uniQure N.V.</inf:issuerName><inf:cusip>N90064101</inf:cusip><inf:isin>NL0010696654</inf:isin><inf:meetingDate>06/10/2026</inf:meetingDate><inf:voteDescription>Approval, on an advisory basis, of the frequency of advisory votes on the compensation of the named  executive officers of the Company.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>12129.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ONE YEAR</inf:howVoted><inf:sharesVoted>12129.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Natera, Inc.</inf:issuerName><inf:cusip>632307104</inf:cusip><inf:isin>US6323071042</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the compensation of Natera, Inc.'s named executive officers as disclosed in the proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>51899.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>51899.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Natera, Inc.</inf:issuerName><inf:cusip>632307104</inf:cusip><inf:isin>US6323071042</inf:isin><inf:meetingDate>06/11/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory (non-binding) basis, the frequency of future advisory votes on the compensation of our named executive officers.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>51899.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>ONE YEAR</inf:howVoted><inf:sharesVoted>51899.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Mirum Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>604749101</inf:cusip><inf:isin>US6047491013</inf:isin><inf:meetingDate>06/15/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>227.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>227.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Cullinan Therapeutics, Inc.</inf:issuerName><inf:cusip>230031106</inf:cusip><inf:isin>US2300311063</inf:isin><inf:meetingDate>06/16/2026</inf:meetingDate><inf:voteDescription>Proposal to vote, on an advisory basis, to approve our named executive officer compensation.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>178590.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>178590.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Madrigal Pharmaceuticals, Inc.</inf:issuerName><inf:cusip>558868105</inf:cusip><inf:isin>US5588681057</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>Advisory vote to approve executive compensation</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY VOTES</inf:categoryType></inf:voteCategory></inf:voteCategories><inf:sharesVoted>158.000000</inf:sharesVoted><inf:sharesOnLoan>0</inf:sharesOnLoan><inf:vote><inf:voteRecord><inf:howVoted>FOR</inf:howVoted><inf:sharesVoted>158.000000</inf:sharesVoted><inf:managementRecommendation>FOR</inf:managementRecommendation></inf:voteRecord></inf:vote></inf:proxyTable><inf:proxyTable><inf:issuerName>Structure Therapeutics Inc.</inf:issuerName><inf:cusip>86366E106</inf:cusip><inf:isin>US86366E1064</inf:isin><inf:meetingDate>06/17/2026</inf:meetingDate><inf:voteDescription>To approve, on an advisory basis, the compensation of the Company's named executive officers, as disclosed in the proxy statement.</inf:voteDescription><inf:voteCategories><inf:voteCategory><inf:categoryType>SECTION 14A SAY-ON-PAY 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