75000 - Document - Document and Entity Information
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75010 - Statement - Condensed Consolidated Balance Sheets (Unaudited)
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75020 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) (Unaudited)
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75030 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) (Unaudited)
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75040 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited)
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75050 - Statement - Condensed Consolidated Statements of Changes in Stockholders' Equity (Parenthetical) (Unaudited)
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75060 - Statement - Condensed Consolidated Statements of Cash Flows (Unaudited)
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995455 - Disclosure - Description of Business
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Net Income (Loss) per Common Share
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995485 - Disclosure - Financial Instruments
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995495 - Disclosure - Property and Equipment
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995505 - Disclosure - Out-license Agreements
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995515 - Disclosure - Liability Related to the Sale of Future Revenues
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995525 - Disclosure - Sale of ATOM Facility
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995535 - Disclosure - Leases
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995545 - Disclosure - Restructuring
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995555 - Disclosure - Commitments and Contingencies
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995565 - Disclosure - Stockholders' Equity (Deficit)
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995575 - Disclosure - Supplemental Balance Sheet Information
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995585 - Disclosure - Subsequent Event
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995595 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995605 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995615 - Disclosure - Net Income (Loss) per Common Share (Tables)
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995625 - Disclosure - Financial Instruments (Tables)
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995635 - Disclosure - Out-license Agreements (Tables)
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995645 - Disclosure - Liability Related to the Sale of Future Revenues (Tables)
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995655 - Disclosure - Property and Equipment (Tables)
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995665 - Disclosure - Sale of ATOM Facility (Tables)
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995675 - Disclosure - Leases (Tables)
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995685 - Disclosure - Restructuring (Tables)
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995695 - Disclosure - Commitments and Contingencies (Tables)
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995705 - Disclosure - Stockholders' Equity (Deficit) (Tables)
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995715 - Disclosure - Supplemental Balance Sheet Information (Tables)
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995725 - Disclosure - Description of Business (Detail)
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995735 - Disclosure - Summary of Significant Accounting Policies - Summary Of Comprehensive Income Loss (Details)
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995745 - Disclosure - Summary of Significant Accounting Policies (Additional Information) (Details)
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995755 - Disclosure - Net Income (Loss) per Common Share - Reconciliation Of computing of EPS (Details)
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995765 - Disclosure - Net Income (Loss) per Common Share- Antidilutive Securities Excluded From Computation of Diluted Net Loss per Common Share (Detail)
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995775 - Disclosure - Financial Instruments - Summary of Estimated Fair Value and Related Valuation Input Hierarchy of Available-for-Sale Securities (Detail)
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995785 - Disclosure - Financial Instruments - Amortized Cost and Fair Value of Available-for-Sale Securities by Contractual Maturity (Detail)
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995795 - Disclosure - Financial Instruments - Additional Information (Detail)
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995805 - Disclosure - Financial Instruments - Reconciliation of Cash, Cash Equivalents and Restricted Cash (Detail)
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995815 - Disclosure - Property and Equipment - Schedule of Property and Equipment (Detail)
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995825 - Disclosure - Property and Equipment - Additional Information (Detail)
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995835 - Disclosure - Out-license Agreements - Schedule of Deferred Revenue Activity (Details)
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995845 - Disclosure - Out-license Agreements - Additional Information (Detail)
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995855 - Disclosure - Liability Related to the Sale of Future Revenues - Schedule of Liability Related to the Sale of Future Revenues (Details)
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995865 - Disclosure - Liability Related to the Sale of Future Revenues (Additional Information) (Details)
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995875 - Disclosure - Sale of ATOM Facility - Summary of assets and gain sales (Details)
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995885 - Disclosure - Sale of ATOM Facility - Additional Information (Details)
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995895 - Disclosure - Leases (Additional Information) (Details)
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995905 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities Under Operating and Finance Leases (Details)
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995915 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities Under Operating and Finance Leases (Details) 2
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995925 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities Under Operating and Finance Leases (Details) 3
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995935 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities Under Operating and Finance Leases (Details) 4
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995945 - Disclosure - Leases - Components of Lease Cost (Details)
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995955 - Disclosure - Leases - Components of Lease Cost (Details) 2
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995965 - Disclosure - Leases - Summary of Other Information Related to Leases (Details)
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995975 - Disclosure - Restructuring (Additional Information) (Details)
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995985 - Disclosure - Restructuring - Summary of future termination benefit payments (Details)
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995995 - Disclosure - Restructuring - Restructuring liability activity (Details)
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996005 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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996015 - Disclosure - Stockholders' Equity (Deficit) - Additional Information (Detail)
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996025 - Disclosure - Stockholders' Equity (Deficit) - Summary of RSU Activity (Detail)
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996035 - Disclosure - Stockholders' Equity (Deficit) - Summary of Stock Option Activity (Detail)
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996045 - Disclosure - Stockholders' Equity (Deficit) - Schedule of Common Stock Reserved for Future Issuance Under Equity Incentive Plans (Detail)
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996055 - Disclosure - Stockholders' Equity (Deficit) - Schedule of Stock-based Compensation Related to All Employee And Non-employee Stock Awards (Detail)
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996065 - Disclosure - Supplemental Balance Sheet Information (Additional Information) (Details)
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996075 - Disclosure - Supplemental Balance Sheet Information - Schedule of Inventories (Details)
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996085 - Disclosure - Supplemental Balance Sheet Information - Schedule of Property and Equipment (Details)
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996095 - Disclosure - Supplemental Balance Sheet Information - Schedule of Other Current Liabilities (Details)
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996105 - Disclosure - Subsequent Event (Additional Information) (Details)
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Common stock capital additional shares reserved for future issuance.
Common Stock Capital Additional Shares Reserved For Future Issuance
Additional shares of common stock, reserved for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Vested
Proceeds from sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Restructuring Reserve, Total
Restructuring Reserve
Liability balance, ending balance
Liability balance, beginning balance
Finance Lease Other Long Term Liabilities
Finance Lease Other Long Term Liabilities
Finance Lease Other Long Term Liabilities
Total
Present value of lease liabilities
Finance Lease, Liability
Finance Lease, Liability, Total
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Entity incorporation state
Finance Lease, Liability, to be Paid, Year Four
Finance leases, 2028
Processing Rooms
Processing Rooms [Member]
Processing rooms member.
Direct Registered Offering [Member]
Direct Registered Offering [Member]
Direct Registered Offering
Accounts payable
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Non-cash financing activities
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Maturing within one year, Estimated fair value
Contractual obligations due to licensors.
Contractual Obligations Due To Licensors
Contractual obligations due to Bayer, MSK and QIMR
Plan Name [Axis]
Plan Name
Increase Decrease Milestone Payment
Increase Decrease Milestone Payment
Reduce Milestone Payment
Entity Current Reporting Status
Entity Current Reporting Status
Reconciliation of Share Amount used in Computing Earnings Per Share [Table Text Block]
Reconciliation of share amount used in computing earnings per share.
Reconciliation of Computing of EPS
Expire from date of grant.
From Date Of Grant [Member]
From Date Of Grant
Costs and operating expenses:
Operating Expenses [Abstract]
Level 2
Fair Value, Inputs, Level 2 [Member]
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Product and Service [Axis]
Document Fiscal Period Focus
Document Fiscal Period Focus
Finance leases, Total minimum payments
Finance Lease, Liability, to be Paid
Entity Shell Company
Entity Shell Company
Contractual obligations
Contractual Obligation
Contractual Obligation, Total
Other accrued liabilities
Other Accrued Liabilities, Current
All Milestones [Member]
All Milestones [Member]
All Milestones [Member]
May 2020 [Member]
May 2020 Warrants [Member]
Short-Term Investments [Member]
Amounts Classified As Short-Term Investments
Segment Reporting, Policy [Policy Text Block]
Segment and Geographic Information
Cash and Cash Equivalent
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Operating Lease, Impairment Loss
Loss on impairment of lease right-of-use asset
Regulatory Milestone
Regulatory Milestone
Regulatory Milestone
RSU Releases Shares During Period
RSU Releases Shares During Period
RSU releases
Common Stock, Shares, Issued
Common stock, shares issued
Common Stock, Shares, Issued, Total
Schedule of Minimum Commitments
Recorded unconditional service obligations.
Recorded Unconditional Service Obligations [Text Block]
Statement [Table]
Statement [Table]
Restricted cash - long term
Restricted Cash, Noncurrent
Operating lease assets obtained in exchange for lease obligations:
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Proceeds from issuance of common stock gross.
Proceeds From Issuance Of Common Stock Gross
Proceeds from sale of pre-funded warrants to purchase common stock, gross
Interest Receivable
Accrued interest receivable
Medical and Safety Expense
Medical and Safety Expense
Medical and safety expense
Long-Term Purchase Commitment, Category of Item Purchased [Domain]
Cash Payment
Cash Payment
Cash Payment
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Percentage of employees purchase price of common stock
Total other income (expense), net
Total other income (expense), net
Total other income (expense), net
Statement [Line Items]
Statement [Line Items]
December 2020 Warrants [Member]
December 2020 Warrants [Member]
Warrant [Member]
Warrant
Entity Filer Category
Entity Filer Category
Material rights, term
Material Rights, Term
Material rights, term
Total liabilities and stockholders' equity (deficit)
Liabilities and Equity
Increase (Decrease) in Employee Related Liabilities
Accrued compensation
Increase (Decrease) in Employee Related Liabilities, Total
Accounts compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable, Weighted Average Exercise Price
Restructuring Type [Axis]
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Severance Costs
Severance Costs
Finance Lease, Liability, to be Paid, Year Three
Finance leases, 2027
Bayer Manufacturing Agreement.
Bayer Manufacturing Agreement [Member]
Bayer Manufacturing Agreement
Financial Instruments
Financial Instruments Disclosure [Text Block]
Summarizes of future termination benefit payments
Restructuring and Related Costs [Table Text Block]
Liability for Future Policy Benefit, after Reinsurance [Abstract]
Shares Issued, Price Per Share
Shares Issued, Price per Share
Subsequent Event [Line Items]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Schedule of Maturities of Lease Liabilities Under Operating and Finance Leases
ScheduleOfMaturitiesOfLeaseLiabilitiesUnderOperatingAndFinanceLeasesTableTextBlock
ScheduleOfMaturitiesOfLeaseLiabilitiesUnderOperatingAndFinanceLeasesTableTextBlock
Geographical [Domain]
Asset-Backed Securities [Member]
Asset-Backed Securities
Office Space
Office Space [Member]
Office Space member.
Schedule of Inventories
Schedule of Inventory, Current [Table Text Block]
Lease agreement area of office lab and warehouse space.
Lease Agreement Area Of Office Lab And Warehouse Space
Lease agreement area of square feet of office, lab and warehouse space
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award
Stock option granted description terms
Liability Related to the Sale of Future Revenues
Liability for Future Policy Benefits and Unpaid Claims Disclosure [Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted, Shares
Proceeds from Sale of Other Assets
Payment Received form Sale of Assets
Proceeds from sale of future royalties, gross
Proceeds from sale of future royalties, gross
Proceeds from sale of future royalties, gross
Investments Classified by Contractual Maturity Date [Table Text Block]
Amortized Cost and Fair Value of Available for Sale Securities by Contractual Maturity
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Basic (loss) earnings per common share
Two thousand nineteen warrants.
Two Thousand Nineteen Warrants [Member]
2019 Warrants
Milestone Type [Axis]
Milestone Type [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Outstanding, Shares, ending balance
Outstanding, Shares, beginning balance
Liabilities, Current
Total current liabilities
Accounts receivable
Increase (Decrease) in Accounts Receivable
Accounts receivable
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year Five
Operating leases, 2030
Cash equivalents, amortized cost.
Cash Equivalents Amortized Cost
Total Amortized Cost
Total Amortized Cost
Debt Securities, Available-for-Sale, Fair Value, Fiscal Year Maturity [Abstract]
Estimated Fair value
WeightedAverageRemainingLeaseTermAbstract
WeightedAverageRemainingLeaseTermAbstract
Weighted Average Remaining Lease Term
Non-Cash Impairment of Lease Right-of-Use Asset
Non-Cash Impairment of Lease Right-of-Use Asset
Non-cash impairment of the right-of-use asset
Stockholders' equity (deficit):
Equity, Attributable to Parent [Abstract]
Entity Small Business
Entity Small Business
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Accretion of liability related to sale of future revenues
Accretion of interest expense on liability related to sale of future revenues
Accretion Expense
Restricted Stock, Value, Shares Issued Net of Tax Withholdings
RSU settlements, net of shares withheld
Less:
Less
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Forfeited or expired, Shares
Class of warrant or right number of warrants issued.
Class Of Warrant Or Right Number Of Warrants Issued
Number of warrants issued
Purchases of short-term investments
Payments to Acquire Short-Term Investments
Purchases of short-term investments
Issuance of common stock pursuant to employee stock awards value.
Issuance Of Common Stock Pursuant To Employee Stock Awards Value
Issuance of common stock pursuant to employee stock awards
FinanceLeaseCost
Total finance lease cost
FinanceLeaseCost
Leases [Abstract]
Contract with Customer, Liability
Deferred revenue
Contract with Customer, Liability, Total
Deferred revenue, January 1, 2026
Deferred revenue June 30, 2026
Lessee, Lease, Description [Line Items]
Amendment Flag
Amendment Flag
Operating Lease Right-of-Use Asset, Accelerated Amortization Expense
Operating Lease Right-of-Use Asset, Accelerated Amortization Expense
Accelerated amortization expense on right-of-use asset
Product and Service [Domain]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Cash equivalents, accumulated gross unrealized gain, before tax.
Cash Equivalents Accumulated Gross Unrealized Gain Before Tax
Total Unrealized Gain
Employees Count
Employees Count
Supply agreement maximum extension term.
Supply Agreement Maximum Extension Term
Supply agreement maximum extension term
The entire disclosure for the business description concept. Business description describes the nature and type of organization including but not limited to organizational structure as may be applicable to holding companies, parent and subsidiary relationships, business divisions, business units, business segments, affiliates and information about significant ownership of the reporting entity.
Business Description [Text Block]
Description of Business
Warrants issued to purchase common stock
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Interest on lease liabilities
Finance Lease, Interest Expense
Proceeds from transaction cost
Proceeds from transaction cost
Liabilities and stockholders' equity (deficit)
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Common Stock [Member]
Common Stock
Class of warrant or right, term.
Class Of Warrant Or Right Term
Warrants, term
May 2025 Pre-funded Warrants [Member]
May 2025 Pre-funded Warrants [Member]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted, Weighted Average Exercise Price
Lessee, Operating Lease, Liability, to be Paid, Year Three
Operating leases, 2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Other Operating Income (Expense), Net
Other segment items
Debt Securities, Available-for-Sale [Line Items]
Schedule of Available-for-sale Securities [Line Items]
January Twenty Thousand Twenty Five Reduction [Member]
January Twenty Thousand Twenty Five Reduction [Member]
January 2025
Payment exchange reduction amount
Payment exchange reduction Amount
Payment exchange reduction Amount
Entity Address, Address Line One
Entity Address, Address Line One
Fair Value Hierarchy and NAV [Axis]
Net earnings (loss) per common share:
Earnings Per Share [Abstract]
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Amortized Cost
Total available-for-sale securities, Amortized cost
Supplemental Cash Flow Information [Abstract]
Supplemental cash flow disclosure
Costs Incurred Relatedto Performance Obligations Includedin R&D
Costs Incurred Relatedto Performance Obligations Includedin R&D
Costs Incurred Relatedto Performance Obligations Includedin R&D
Non cash operating lease expense.
Non Cash Operating Lease Expense
Non-cash operating lease expense
Operating Lease, Right-of-Use Asset
Operating lease assets
Less: amount representing interest
Less: amount representing interest
Finance Lease, Liability, Undiscounted Excess Amount
Gain on sale of ATOM Facility
Gain on sale of ATOM Facility
Gain (Loss) on Sale of Investments
Increase (Decrease) in Other Operating Assets and Liabilities, Net [Abstract]
Changes in operating assets and liabilities:
Class of Warrant or Right [Axis]
Class of Warrant or Right
Document Type
Document Type
At the market offering.
At The Market Offering [Member]
At The Market Offering
Income Taxes Paid, Net
Income Taxes Paid, Net, Total
Cash paid for income taxes
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Decrease Increase in Finance Lease Assets and Liabilities Upon Derecognition
Decrease Increase in Finance Lease Assets and Liabilities Upon Derecognition
Decrease in finance lease liabilities upon derecognition
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Entity Central Index Key
Entity Central Index Key
Increase (decrease) in cash, cash equivalents and restricted cash
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Excluding Exchange Rate Effect, Including Discontinued Operation
Subsequent Event Type [Domain]
Platform Sciences Development and Operations Expense
Platform Sciences Development and Operations Expense
Technical operations and quality expense
Interest income
Interest Income, Operating
Interest Income, Operating, Total
Increase (decrease) in accrued research and development.
Increase Decrease In Accrued Research And Development
Accrued research and development expenses
Accrued research and development expenses
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities excluded from computation of earnings per share
Received tiered royalties on net sales, percentage
Received Tiered Royalties On Net Sales
Received Tiered Royalties On Net Sales
Supplemental Balance Sheet Information [Table]
Supplemental Balance Sheet Information [Table]
Common Stock, Par or Stated Value Per Share
Common stock, par value
Common stock exercise price
Operating Lease, Right-of-Use Asset, Periodic Reduction
Amortization expense on right-of-use asset
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Outstanding, Weighted Average Remaining Contractual Term
Debt Securities, Available-for-Sale, Amortized Cost
Total Amortized Cost
Total Amortized Cost
Debt Securities, Available-for-Sale
Total Fair Value
Total Fair Value
Gain (Loss) on Termination of Lease
Gain on derecognition of lease liabilities
Gain on derecognition of lease liabilities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercised, Shares
Accrued operating expenses
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Letter of credit issued, classified as long-term restricted cash
Restricted Cash and Cash Equivalent, Noncurrent
Restricted Cash and Cash Equivalents, Noncurrent, Total
Document Quarterly Report
Document Quarterly Report
HCRx Royalties [Member]
HCRx Royalties [Member]
Entity Address, State or Province
Entity Address, State or Province
Amortization (accretion) of investment premiums (discounts)
Investment Income, Net, Amortization of Discount and Premium
Investment Income, Net, Amortization of Discount and Premium, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Balance as of December 31, 2025
Balance as of June 30, 2026
Liability Related To The Sale Of Future Royalties
Liability Related To The Sale Of Future Royalties
Liability related to sale of future revenues as of January 1, 2026
Liability related to the sale of future revenues as of June 30, 2026
Equity Warrants As A Charge
Equity Warrants As A Charge
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Comprehensive income (loss)
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Total Unrealized Gain
Common Stock, Capital Shares Reserved for Future Issuance
Total reserved shares of common stock
Shares of common stock, reserved for issuance
Sale of ATOM Facility
Disposal Groups, Including Discontinued Operations, Disclosure [Text Block]
Class of Warrant or Right [Domain]
Class of Warrant or Right
Geographical [Axis]
Weighted Average Discount Rate
WeightedAverageDiscountRateAbstract
WeightedAverageDiscountRateAbstract
Non-cash Investing and Financing Activities Accrued Costs Related to Direct Registered Offering
Non-cash Investing and Financing Activities Accrued Costs Related to Direct Registered Offering.
Accrued costs related to underwritten registered direct offering
Liability related to sale of future revenues - long-term
Liability related to the sale of future revenues - long-term
Liability related to the sale of future royalties - long-term
Liability related to the sale of future royalties - long-term
Liability related to the sale of future revenues - long-term
Liability related to sale of future revenues as of January 1, 2024
Accrued research and development expenses current.
Accrued Research And Development Expenses Current
Accrued research and development expenses
Raw Materials
Inventory, Raw Materials, Gross
Payments for royalties
Repayment of the liability
Payments for Royalties
Repayment of the liability
Warrants Exercised
Warrants Exercised
Warrants exercised
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Stock-based Compensation, Related to Employee and Nonemployee Stock Awards
Finance leases, Thereafter
Finance Lease, Liability, to be Paid, after Year Five
Proceeds from royalties
Proceeds from Royalties Received
Employees and non-employees.
Employees And Non Employees [Member]
Employees And Non Employees
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive gain (loss):
Subsequent Event [Member]
Subsequent Event [Member]
Cash equivalents, fair value.
Cash Equivalents Fair Value
Total Fair Value
Cash Equivalents Fair Value, Total
Total Fair Value
Property, Plant and Equipment [Abstract]
Issuance Of Common Stock Through A T M Facilities Net Of Commissions And Offering Costs Value
Issuance Of Common Stock Through A T M Facilities Net Of Commissions And Offering Costs Value
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Prior notice period to increase or decrease maximum ownership percentage.
Prior Notice Period To Increase Or Decrease Maximum Ownership Percentage
Prior notice period
Pierre Fabre [Member]
Pierre Fabre [Member]
Pierre Fabre
Antidilutive Securities [Axis]
Antidilutive Securities
Vested and expected to vest, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Common stock average price.
Common Stock Average Price
Common stock average price
Lab equipment [Member]
Lab Equipment [Member]
Lab Equipment [Member]
Schedule of license, collaboration and manufacturing agreements.
Schedule Of License Collaboration And Manufacturing Agreements [Table]
Schedule Of License Collaboration And Manufacturing Agreements [Table]
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss)
Cash Received
Cash Received
Summary of the carrying amount assets sold and the gain on sale
Asset Acquisition, Contingent Consideration [Table Text Block]
Lease option to extend additional term
Lessee, Operating Lease, Option to Extend
Lease Premises Terminated
Lease Premises Terminated
Lease Premises Terminated
Minimum [Member]
Minimum [Member]
Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Financial Instrument [Axis]
Assets, Current [Abstract]
Current assets:
Common Stocks, Including Additional Paid in Capital, Net of Discount [Abstract]
Other comprehensive loss
Other Comprehensive Income (Loss), Tax
Other Comprehensive Income (Loss), Tax, Total
Gain (Loss) on Sale of Assets and Asset Impairment Charges
Impairment loss
Class of Warrant or Right, Number of Securities Called by Each Warrant or Right
Number of securities called by each warrant
Other assets
Disposal Group, Including Discontinued Operation, Other Liabilities, Current
Liabilities, Current [Abstract]
Current liabilities:
Restructuring and Related Activities Disclosure [Text Block]
Restructuring
Payments Received from Sale of Inventory
Payments Received from Sale of Inventory
Payments received from sale of inventory
Schedule of Other Current Liabilities
Other Current Liabilities [Table Text Block]
Embedded Leases
Embedded Leases Member
Embedded Leases Member
Shares, Outstanding
Ending balance (in shares)
Beginning balance (in shares)
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Liabilities related to indemnification agreements.
Liabilities Related To Indemnification Agreements
Liabilities related to indemnification agreements
Letter of credit maintained
Restricted Cash and Cash Equivalent
Restricted Cash and Cash Equivalents, Total
Proceeds from Stock Plans
Proceeds from employee stock awards
Sub Licensing Fees
Sub Licensing Fees
Sub Licensing Fees
Commitments and Contingencies
Commitments and contingencies (Note 9)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Balance as of December 31, 2025
Balance as of June 30, 2026
Work-in-process
Inventory, Work in Process, Gross
Non-Cash Settlements Adjustments
Non-Cash Settlements Adjustments
Non-cash settlements/adjustments
Minimum cash repayment
Minimum Cash Repayment
Minimum cash repayment.
General and Administrative Expense [Member]
General and administrative
Total
Operating Lease, Liability
Operating Lease, Liability, Total
Operating lease, liability
Deferred Income, Current
Deferred revenue
Stockholders' Equity, Reverse Stock Split
Reverse Stock Split
Restricted cash
Restricted Cash, Current
Restricted cash - short term
Inducement plan.
Inducement Plan [Member]
Inducement Plan
Category of Item Purchased [Axis]
South San Francisco California.
South San Francisco California [Member]
South San Francisco California
Current portion of finance lease liabilities
Other current liabilities
Finance Lease, Liability, Current
Lessee, Lease, Description [Table]
Finance leases
Finance Lease, Weighted Average Discount Rate, Percent
Net income (loss)
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Technical operations and quality expense
Technical Operations And Quality Expense
Technical Operations And Quality Expense
Loss Contingencies [Table]
Loss Contingencies [Table]
Other current assets
Other current assets
Increase (Decrease) in Other Current Asset
Increase (Decrease) in Other Current Asset
Weighted average shares outstanding - Basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Basic weighted-average shares outstanding
Percentage of commission to be paid on gross sales proceeds of common stock sold.
Percentage Of Commission To Be Paid On Gross Sales Proceeds Of Common Stock Sold
Percentage of commission to be paid on gross sales proceeds of common stock sold
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Exercisable, Aggregate Intrinsic Value
Increase (Decrease) in Other Current Liabilities
Other current liabilities
Other current liabilities
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Issuance of common stock, net of commissions and offering costs, value.
Issuance Of Common Stock Net Of Commissions And Offering Costs Value
Issuance of common stock through ATM facilities, net of commissions and offering costs, value
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
financial instruments disclosure.
Financial Instruments Disclosure [Abstract]
Subsequent Event
Subsequent Events [Text Block]
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
September 2024 Pre-Funded Warrants [Member]
September 2024 Pre-Funded Warrants [Member]
Territory [Axis]
Territory [Axis]
Total stockholders' equity (deficit)
Equity, Attributable to Parent
Ending balance
Beginning balance
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Statement of Stockholders' Equity [Abstract]
Net of transaction costs
Net of Transaction Costs
Net of Transaction Costs
Type of Restructuring [Domain]
Pierre Fabre commercialization agreement.
Pierre Fabre Commercialization Agreement [Member]
Pierre Fabre Commercialization Agreement
Cash Equivalents [Member]
Amounts Classified As Cash Equivalents
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Leasehold Improvements [Member]
Leasehold Improvements [Member]
Entity Address, Address Line Two
Entity Address, Address Line Two
Lease commencement date.
Lease Commencement Date
Lease commencement date
Entity Incorporation, Date of Incorporation
Entity incorporation date
Other current assets
Other Assets, Current
Plan Name [Domain]
Plan Name
Other assets
Increase (Decrease) in Other Operating Assets
Other assets
Increase (Decrease) in Other Operating Assets, Total
Interest expense
Interest expense
Interest Expense, Operating and Nonoperating
Interest Expense, Total
Common stock value remained available to be sold.
Common Stock Value Remained Available To Be Sold
Common stock value remaining to be sold
Finance Lease, Liability, to be Paid, Year One
Finance leases, 2025
Class of Warrant or Right, Outstanding
Warrants outstanding
Warrants outstanding
Maximum cash repayment
Maximum Cash Repayment
Maximum cash repayment.
Restricted Stock, Shares Issued Net of Shares for Tax Withholdings
RSU settlements, net of shares withheld, shares
Restructuring Plan [Axis]
Non Cash Investing And Financing Activities Accrued Costs Related To At The Market Facility
Non cash investing and financing activities accrued costs related to at the market facility.
Accrued costs related to ATM facility
Issuance Of Pre Funded Warrants Net Of Offering Costs
Issuance Of Pre Funded Warrants Net Of Offering Costs
Issuance of pre-funded warrants net of offering costs
Entity Address, City or Town
Entity Address, City or Town
Schedule of Earnings Per Share, Diluted, by Common Class, Including Two Class Method [Table Text Block]
Schedule of Diluted net (loss) earnings per common share
A&R Commercialization Agreement [Member]
A&R Commercialization Agreement [Member]
AR Commercialization Agreement [Member]
Number of Reportable Segments
Number of Reportable Segments
Two thousand eighteen inducement plan.
Two Thousand Eighteen Inducement Plan [Member]
2018 Inducement Plan
Security Exchange Name
Security Exchange Name
Liability for Future Policy Benefit Activity [Table]
Property, Plant and Equipment, Gross
Property and equipment, gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Counterparty Name [Axis]
Counterparty Name
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Income (loss) before provision for (benefit from) income taxes
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest, Shares
Finance Lease, Liability, to be Paid, Year Five
Finance leases, 2029
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Inventory, Net
Total inventories
Inventories
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, cash equivalents and restricted cash at end of period
Cash, cash equivalents and restricted cash at beginning of period
Total cash, cash equivalents and restricted cash
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Aurora Colorado
Aurora Colorado Member
Aurora Colorado Member
Statistical Measurement [Domain]
Statistical Measurement
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrants, exercise price
Warrants, exercise price
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Total stock-based compensation expense
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Exercisable, Shares
Two thousand fourteen employee stock purchase plan.
Two Thousand Fourteen Employee Stock Purchase Plan [Member]
2014 Employee Stock Purchase Plan
Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Freezers member.
Freezers
Freezers [Member]
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs)
Unvested RSUs
Issuance Of Pre Funded Warrants Registered Direct Offering Value
Issuance Of Pre Funded Warrants Registered Direct Offering Value
Issuance of pre-funded warrants to purchase common stock through an underwritten registered direct offering
Common stock reserved for future issuance.
Common Stock Reserved For Future Issuance Table [Text Block]
Schedule of Common Stock Reserved for Future Issuance Under Equity Incentive Plans
Aggregate milestone payments entitle to receive upon achieving certain regulatory and commercial milestones.
Aggregate Milestone Payments Entitle To Receive Upon Achieving Certain Regulatory And Commercial Milestones
Aggregate milestone payments entitle to receive upon achieving certain regulatory and commercial milestones
Additional milestone payments
Additional Milestone Payments
Additional Milestone Payments
Pre-tax gain on sale of business
Disposal Group, Not Discontinued Operation, Gain (Loss) on Disposal
Gain on sale of ATOM Facility
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Class of Stock [Axis]
Supplemental Balance Sheet Information [Line Items]
Supplemental Balance Sheet Information [Line Items]
Reduction of debt in exchange for pre-funded warrants
Reduction of Debt in Exchange for Pre-Funded Warrants
Reduction of Debt in Exchange for Pre-Funded Warrants
Reduction of debt in exchange for pre-funded warrants
Summary of Activity for ARO Liabilities
Schedule of Change in Asset Retirement Obligation [Table Text Block]
Liabilities
Total liabilities
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Domain]
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation
US Government Agencies Short-Term Debt Securities [Member]
Government Agency Obligations
Financial Instruments [Domain]
Capital Units, Authorized
Authorized capital stock
Increase (Decrease) in Deferred Revenue
Deferred revenue
January 2024 Warrants [Member]
January 2024 Warrants [Member]
Lessee, Operating Lease, Liability, to be Paid, Year Two
Operating leases, 2027
Disposal Groups, Including Discontinued Operations [Table]
Amortization expense
Finance Lease, Right-of-Use Asset, Amortization
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted average shares outstanding - Diluted
Weighted Average Number of Shares Outstanding, Diluted
Diluted weighted-average shares outstanding
Property, Plant and Equipment, Net, by Type [Abstract]
Securities Act File Number
Entity File Number
Unrealized gain (loss) on available-for-sale securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized gain (loss) on available-for-sale securities
Out-license Agreements.
Out License Agreements Disclosure [Text Block]
Out-license Agreements
Proceeds from Sale, Maturity and Collection of Short-Term Investments
Proceeds from maturities and sales of short-term investments
Proceeds from Sale, Maturity and Collection of Short-term Investments, Total
Cover [Abstract]
Less: current portion classified within other accrued liabilities
Liability Related To The Sale Of Future Revenue Current
Liability related to the sale of future revenue current.
Liability related to the sale of future revenues - current portion
Less: current portion
Common stock, reserved for future issuance value
Common Stock, Reserved for Future Issuance Value
Common stock, reserved for future issuance value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Shares, Forfeited
Supplemental Balance Sheet Information
Supplemental Balance Sheet Disclosures [Text Block]
US Treasury Securities [Member]
U.S. Treasury Obligations
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Aggregate number of shares authorized
Sale of Stock [Domain]
Sale of Stock
General and administrative expenses
General and Administrative Expense
General and Administrative Expense, Total
Recognized into commercialization revenue
Recognized into commercialization revenue
Deferred Income, Revenue Recognized
Subsequent Event [Table]
Maximum Potential Milestone Payments
Maximum Potential Milestone Payments
Maximum potential milestone payments
CashPaidForAmountsIncludedInMeasurementOfLeaseLiabilitiesAbstract
CashPaidForAmountsIncludedInMeasurementOfLeaseLiabilitiesAbstract
Cash paid for amounts included in the measurement of lease liabilities:
Short-Term Debt, Type [Domain]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Stock options vested and expected to vest, Weighted Average Exercise Price
Restructuring Charges
Total restructuring charges
Restructuring charges
Short-Term Debt, Type [Axis]
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of RSU Activity
Less: deferred revenue - current portion
Less: deferred revenue - current portion
Contract with Customer, Liability, Current
Comprehensive Income (Loss) [Table Text Block]
Schedule Of Comprehensive Income Loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Share based compensation, vesting period
Employee Severance [Member]
Disposal Group, Including Discontinued Operation, Consideration
Cash consideration pursuant to asset purchase agreement
Depreciation
Depreciation, Total
Depreciation expense
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation expense
Liquidity risk.
Liquidity Risk Policy [Text Block]
Liquidity Risk
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Current portion of operating lease liabilities
Other current liabilities
Operating Lease, Liability, Current
Document Transition Report
Document Transition Report
Short-term investments
Short-Term Investments
Short-Term Investments, Total
Property and equipment, net
Disposal Group, Including Discontinued Operation, Property, Plant and Equipment, Noncurrent
Research and development expenses
Research and Development Expense
Research and Development Expense, Total
Number Of transaction cost
Number Of Transacation Cost
Number Of Transacation Cost
Statement of Cash Flows [Abstract]
Two thousand and fourteen equity incentive plan.
Two Thousand And Fourteen Equity Incentive Plan [Member]
2014 Equity Incentive Plan
Development or sales-based milestone payments earned or received.
Development Or Sales Based Milestone Payments Earned Or Received
Development or sales-based milestone payments earned or received
Liability Related to the Sale of Future Revenues
Liability Related to the Sale of Future Revenues Text Block
Liability Related to the Sale of Future Revenues Text Block
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
License, collaboration and manufacturing agreements.
License Collaboration And Manufacturing Agreements [Line Items]
License Collaboration And Manufacturing Agreements [Line Items]
Schedule of Information Provided to CODM [Table Text Block]
Schedule of Information Provided to CODM [Table Text Block]
Schedule of Information Provided to CODM
Stockholders' Equity (Deficit)
Equity [Text Block]
Workforce Retaining
Workforce Retaining
Workforce Retaining
Revenue Recognition Performance Obligation
Revenue Recognition Performance Obligation
Revenue recognition, performance obligation
Earnings Per Share [Text Block]
Net Income (Loss) per Common Share
Discontinued Operations and Disposal Groups [Abstract]
Computer Equipment [Member]
Computer equipment and software [Member]
Net income (loss)
Net (loss) income
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value
Inventories
Increase (Decrease) in Inventories
Increase (Decrease) in Inventories, Total
Operating lease cost
Operating Lease, Cost
Proceeds from (Payment for) Other Financing Activity
Other financing activities, net
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Milestone Payments
Milestone payments
Milestone payments
Operating cash flows for operating leases
Operating Lease, Payments
Liability for Future Policy Benefit, Activity [Line Items]
Going Concern [Policy TextBlock]
Going Concern [Policy TextBlock]
Going Concern
Net proceeds from sale of ATOM Facility
Proceeds from Divestiture of Businesses
Cash received on closing of Fujifilm Transaction
Receivable for early contract
Receivable for early contract
Assets [Abstract]
Assets
Research and Development Arrangement [Member]
Construction in Progress [Member]
Construction in Progress [Member]
Restructuring and Related Activities [Abstract]
Lease option to extend additional term
LeaseOptionToExtendAdditionalTerm
LeaseOptionToExtendAdditionalTerm
Document Fiscal Year Focus
Document Fiscal Year Focus
Thousand Oaks California.
Thousand Oaks California [Member]
Thousand Oaks California
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Axis]
Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Investing activities
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Summary of the carrying amount assets sold and the gain on sale
Carrying Value Of Assets Sold And Gain On Sale [Table Text Block]
Carrying Value Of Assets Sold And Gain On Sale [Table Text Block]
Research and Development Expense [Member]
Research and development
Proceeds from issuance of common stock net.
Proceeds From Issuance Of Common Stock Net
Proceeds from sale of pre-funded warrants to purchase common stock, net
Restructuring Cost and Reserve [Line Items]
License, collaboration and manufacturing agreements.
License Collaboration And Manufacturing Agreements [Abstract]
Upfront and milestone payments
Upfront and Milestone Payments
Upfront and Milestone Payments
Commitments and Contingencies Disclosure [Abstract]
License and collaboration revenue.
License And Collaboration Revenue
License and collaboration revenue
Lessee, Operating Lease, Liability, to be Paid, Year One
Operating leases, 2026
Proceeds from License Fees Received
Proceeds from License Fees Received
Issuance of pre-funded warrants to purchase common stock through an underwritten registered direct offering, Shares
Issuance Of Pre Funded Warrants Registered Direct Offering Shares
Issuance Of Pre Funded Warrants Registered Direct Offering Shares
Operating leases, Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Underwritten public offering.
Underwritten Public Offering [Member]
Underwritten Public Offering
Share-Based Payment Arrangement [Abstract]
Sale of Stock [Axis]
Sale of Stock
Revenues
Revenues, Total
Revenue
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash (used in) provided by investing activities
Warrant Maximum Ownership [Member]
Warrant Maximum Ownership [Member]
Warrant maximum ownership [Member]
Finance leases
Finance Lease, Weighted Average Remaining Lease Term
Title of 12(b) Security
Title of 12(b) Security
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeited or expired, Weighted Average Exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Forfeited
Debt Securities, Available-for-Sale, Amortized Cost, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Maturing in one to five years, Amortized cost
Money Market Funds [Member]
Money Market Funds
Regulatory and Quality Expense
Regulatory and Quality Expense
Regulatory expense
Exercise of pre-funded warrants, Share
Stock Issued During Period Shares Stock Options Exercised Of Pre Funded Warrants
Stock issued during period shares stock options exercised of pre-funded warrants.
MSK License Agreements [Member]
MSK License Agreements [Member]
MSK License Agreements
Other Liabilities, Noncurrent
Other long-term liabilities
Other Liabilities, Noncurrent, Total
Restructuring Plan [Domain]
Description of business.
Description Of Business [Abstract]
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five
Maturing in one to five years, Estimated fair value
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Outstanding, Weighted Average Exercise Price, ending balance
Outstanding, Weighted Average Exercise Price, beginning balance
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Operating lease cost including short term lease.
Operating Lease Cost Including Short Term Lease
Total operating lease cost
Measurement Frequency [Domain]
Measurement Frequency
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Statement of Income Location, Balance [Axis]
Income Statement Location
MSA
MSA [Member]
MSA member.
Trading Symbol
Trading Symbol
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment
Debt Securities, Available-for-Sale, Amortized Cost, Maturity, Allocated and Single Maturity Date, Year One
Maturing within one year, Amortized cost
OperatingLeaseCostAbstract
OperatingLeaseCostAbstract
Operating lease cost:
Commercialization revenue
Commercialization Revenue
Commercialization Revenue
Subsequent Event Type [Axis]
Prepaid expenses and other current assets
Disposal Group, Including Discontinued Operation, Prepaid and Other Assets, Current
Employee-related Liabilities, Current
Accrued compensation
Employee-related Liabilities, Current, Total
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Financing activities
Lease initial term
Lessee, Finance Lease, Term of Contract
Fair Value, Recurring [Member]
Fair Value, Measurements, Recurring
Summary of estimated fair value and related valuation input hierarchy of available-for-sale securities.
Summary Of Estimated Fair Value And Related Valuation Input Hierarchy Of Available For Sale Securities Table [Text Block]
Summary of Estimated Fair Value and Related Valuation Input Hierarchy of Available-for-Sale Securities
Operating leases, Total minimum payments
Lessee, Operating Lease, Liability, to be Paid
Gain on Derecognition of the Finance Lease Liability
Gain on Derecognition of the Finance Lease Liability
Gain on derecognition of finance lease liability
Less: amount representing interest
Less: amount representing interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Cost of commercialization revenue
Cost of Commercialization Revenue
Cost of Commercialization Revenue
Other Restructuring [Member]
Restructuring [Member]
Equity Components [Axis]
Equity Components
Equity Component [Domain]
Equity Component
Upfront cash payment received.
Upfront Cash Payment Received
Upfront cash payment received
Restructuring Labiality Activity Table Text Block
Restructuring Labiality Activity Table Text Block
Restructuring of Labiality Activity
Computer equipment and software.
Computer Equipment And Software [Member]
Computer Equipment and Software
Machinery and Equipment [Member]
Machinery and Equipment [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Share based compensation award expiration period
Restructuring Charges, Statement of Income or Comprehensive Income [Extensible Enumeration]
Depreciation, Depletion and Amortization, Nonproduction
Depreciation and amortization expense
Depreciation, Depletion and Amortization, Nonproduction, Total
Maximum [Member]
Maximum [Member]
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised, Weighted Average Exercise Price
Contract with Customer, Liability, Noncurrent
Deferred revenue - long-term
Deferred revenue - long-term, June 30, 2026
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common stock - $0.0001 par value, 500,000 shares authorized as of June 30, 2026 and December 31, 2025; 9,443 and 7,324 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively
Other long-term liabilities
Other Long-Term Debt, Current
Financing cash flows for finance leases
Finance Lease, Principal Payments
Principal payments on finance lease obligations
Financing cash flows for finance leases
Agreement early termination liability
Liabilities Subject to Compromise, Early Contract Termination Fees
Equipment [Member]
Lab Equipment
Maximum ownership percentage.
Maximum Ownership Percentage
Maximum ownership Percentage
Share based compensation arrangement by share based payment award equity instruments options and restricted stock units outstanding.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Options And Restricted Stock Units Outstanding
Outstanding options and RSUs
Amortization of debt discount and debt issuance costs
Amortization of Debt Issuance Costs
Incremental contractual obligations under lease amendment
IncrementalContractualObligationsUnderLeaseAmendment
IncrementalContractualObligationsUnderLeaseAmendment
Other income (expense), net:
Other Nonoperating Income (Expense) [Abstract]
Cowen and Company Limited Liability Company.
Cowen And Company Limited Liability Company [Member]
Cowen
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Total costs and operating expenses
Costs and Expenses
Effect of Dilutive Securities Shares
Effect of Dilutive Securities Shares
Effect of dilutive securities
Entity Registrant Name
Entity Registrant Name
Revenue Recognition Performance Satisfied or Partially Satisfied Prior Period
Revenue Recognition Performance Satisfied or Partially Satisfied Prior Period
Revenue recognition, performance satisfied or partially satisfied prior period
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Total Unrealized Loss
Total Unrealized Loss
Commercialization Revenue [Member]
Commercialization Revenue [Member]
Commercialization Revenue [Member]
Other income (expense), net
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Subsequent Events [Abstract]
Gain on derecognition of operating lease liability
Gain on Derecognition of the Operating Lease Liability
Gain on Derecognition of the Operating Lease Liability
Reduction in current workforce
Reduction In Current Workforce Percentage
Reduction in current workforce percentage
Provision for (benefit from) income taxes
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Measurement Frequency [Axis]
Measurement Frequency
Aggregate Offering Price of common stock.
Aggregate Offering Price Of Common Stock
Common stock aggregate offering price
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock through ATM facilities, net
Other non-cash items, net
Other non-cash items, net
Other non-cash items, net
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Deferred Revenue, Revenue Recognized
Deferred revenue, revenue recognized
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income (loss)
Supplemental Unemployment Benefits, Severance Benefits
Supplemental Unemployment Benefits, Severance Benefits
Determined upfront payment constituted entire consideration included in transaction price.
Determined Upfront Payment Constituted Entire Consideration Included In Transaction Price
Determined upfront payment constituted entire consideration included in transaction price
Leases
Leases Disclosure [Text Block
Leases disclosure.
Cash payments
Payments for Restructuring
Cash payments restructuring
Gain (Loss) on Investments
Gain (Loss) on Investments, Total
Gain (Loss) on Investments,
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Shares, Granted
Accrued termination charges.
Accrued Termination Charges
Accrued termination charges
Assets
Total assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable, Weighted Average Remaining Contractual Term
Income Statement [Abstract]
Restructuring Cost [Table]
Gross proceeds from sale
Gross Proceeds From Sale
Gross Proceeds From Sale
Operating cash flows for finance leases
Finance Lease, Interest Payment on Liability
Accrued expense restructuring
Accrued expense restructuring
Accrued expense restructuring
Issuance of Pre Funded Warrants in Connection With a Debt Modification
Issuance of Pre Funded Warrants in Connection With a Debt Modification
Issuance of pre-funded warrants in connection with HCRx Amendment
Additional Upfront Payment Included inTransaction Price
Additional Upfront Payment Included inTransaction Price
Additional Upfront Payment Included inTransaction Price
Stock Issued During Period, Shares, New Issues
Common stock, shares issued
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Shares, Vested
Write off of accrued interest receivable.
Write Off Of Accrued Interest Receivable
Write off, of accrued interest receivable
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Diluted (loss) earnings per common share
Additions
Deferred Income, Addition
Additions
City Area Code
City Area Code
Increase (decrease) in operating lease liabilities.
Increase Decrease In Operating Lease Liabilities
Operating lease liabilities
Operating lease liabilities
2014 EIP and Inducement Plan.
Two Thousand Fourteen Equity Incentive Plan And Inducement Plan [Member]
2014 EIP and Inducement Plan
Counterparty Name
Counterparty Name [Domain]
Cash equivalents, accumulated gross unrealized loss, before tax.
Cash Equivalents Accumulated Gross Unrealized Loss Before Tax
Total Unrealized Loss
Total Unrealized Loss
Proceeds from Sale of Pre-funded Warrants to Purchase Common Stock in a Registered Direct Offering, Net
Proceeds from sale of pre-funded warrants to purchase common stock in a registered direct offering, net.
Proceeds from sale of pre-funded warrants to purchase common stock in an underwritten registered direct offering or registered direct offering, net
Operating leases
Operating Lease, Weighted Average Remaining Lease Term
Lease expiration date
Lease Expiration Date
Liability related to sale of future royalties
Prepaid Royalties
Liability related to sale of future revenues as of January 1, 2024
Liability related to sale of future revenues as of March 31, 2024
FinanceLeaseCostsAbstract
FinanceLeaseCostsAbstract
Finance lease cost:
Line of credit
Letter of Credit [Member]
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Operating lease assets obtained in exchange for lease obligations
Right-of-Use Asset Obtained in Exchange for Finance Lease Liability
Summary of Other Information Related to Leases
SummaryOfOtherInformationRelatedToLeasesTableTextBlock
SummaryOfOtherInformationRelatedToLeasesTableTextBlock
Percentage of annual increase in base rent
LesseeOperatingLeasePercentageOfAnnualIncreaseInBaseRent
LesseeOperatingLeasePercentageOfAnnualIncreaseInBaseRent
Operating Income (Loss)
Income (loss) from operations
Retained Earnings [Member]
Accumulated Deficit
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
2024 Equity Incentive Plan
Two Thousand And Twenty Four Equity Incentive Plan [Member]
Two Thousand And Twenty Four Equity Incentive Plan [Member]
Net assets sold, Total
Net assets sold
Net assets sold
Issuance of common stock pursuant to employee stock awards shares.
Issuance Of Common Stock Pursuant To Employee Stock Awards Shares
Issuance of common stock pursuant to employee stock awards, shares
Operating leases
Operating Lease, Weighted Average Discount Rate, Percent
Severance and related benefits costs
Severance And Related Benefits Costs
Severance And Related Benefits Costs
Operating lease liabilities - long-term
Operating Lease, Liability, Noncurrent
Operating lease liabilities - long-term
Level 1
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Class Of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Components of Lease Cost
Lease, Cost [Table Text Block]
HCRx Agreement [Member]
HCRx Agreement [Member]
HCRx Agreement [Member]
Interest rate of royalties, percentage
Interest Rate of Royalties, percentage
Interest rate of royalties, percentage
Supplemental Balance Sheet Information [Abstract]
Supplemental Balance Sheet Information [Abstract]
Fujifilm master services and supply agreement.
Fujifilm Master Services And Supply Agreement [Member]
Fujifilm Master Services and Supply Agreement
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Antidilutive Securities Excluded From Computation of Diluted Net Loss per Common Share
Corporate Debt Securities [Member]
Corporate Debt Obligations
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Operating activities
Furniture and Fixtures [Member]
Furniture and Fixtures [Member]
Two Thousand Twenty Three ATM Facility [Member]
Two Thousand Twenty Three ATM Facility [Member]
2023 ATM [Member]
Increase (Decrease) in Other Noncurrent Liabilities
Other long-term liabilities
Payments to acquire lease receivables
Payments to Acquire Lease Receivables
Investment amount
Minimum purchase commitments accrued
Minimum purchase commitments accrued
Minimum purchase commitments accrued
Entity Tax Identification Number
Entity Tax Identification Number
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Amortized Cost [Abstract]
Amortized cost
Liability Related To The Sales Of Future Revenues Table Text Block
Liability Related To The Sales Of Future Revenues Table Text Block
Schedule of Liability Related to the Sale of Future Revenues
Employee stock purchase plan.
Employee Stock Purchase Plan [Member]
ESPP Share Purchase Rights
Minimum commitments Expense
Minimum commitments Expense
Minimum commitments Expense
Issuance and sale of shares of common stock for total proceeds
Proceeds from Issuance or Sale of Equity
Proceeds from Issuance or Sale of Equity, Total
Local Phone Number
Local Phone Number
Territory [Domain]
Territory [Domain]
Total other current liabilities
Other Liabilities, Current
Other current liabilities
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation
Short-term lease cost
Short-Term Lease, Cost
Finance Lease, Liability, to be Paid, Year Two
Finance leases, 2026
Milestone Type, Name [Domain]
Milestone Type, Name [Domain]
Decrease Increase in Operating Lease Assets and Liabilities Upon Derecognition
Decrease Increase in Operating Lease Assets and Liabilities Upon Derecognition
Decrease in operating lease liabilities upon derecognition
Accounting Policies [Abstract]
Deferred Revenue, by Arrangement, Disclosure [Table Text Block]
Schedule of Deferred Revenue Activity
Royalty eligible to receive term after first commercial sale.
Royalty Eligible To Receive Term After First Commercial Sale
Royalty eligible to receive term after first commercial sale
Earnings Per Share, Basic, by Common Class, Including Two-Class Method [Table]
Lessee, Operating Lease, Liability, to be Paid, Year Four
Operating leases, 2029
Issuance of Common Stock, Net of Commissions and Offering Costs, Shares.
Issuance Of Common Stock Net Of Commissions And Offering Costs Shares
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares
Class of Stock [Domain]
Commercial Paper [Member]
Commercial Paper
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Aggregate number of awards available for grant to be issued
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation weighted average recognition period
Cash equivalents and short-term investments
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Additional Territory [Member]
Additional Territory [Member]
Additional Territory [Member]
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Lease agreement area of office lab and cellular therapy manufacturing space
LeaseAgreementAreaOfOfficeLabAndManufacturingSpace
LeaseAgreementAreaOfOfficeLabAndManufacturingSpace
Entity Emerging Growth Company
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Stock options vested and expected to vest, Weighted Average Remaining Contractual Term