Segment Reporting - Summary of Segment Net Loss Including Significant Segment Expenses (Details) - USD ($) $ in Thousands |
3 Months Ended | 6 Months Ended | ||||
|---|---|---|---|---|---|---|
Jun. 30, 2026 |
Mar. 31, 2026 |
Jun. 30, 2025 |
Mar. 31, 2025 |
Jun. 30, 2026 |
Jun. 30, 2025 |
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| Segment Reporting Information [Line Items] | ||||||
| Revenue | $ 9,839 | $ 63,745 | $ 24,362 | $ 81,144 | ||
| Restructuring and related costs | (201) | (18,422) | (243) | (39,465) | ||
| Operating expenses | (39,727) | (67,090) | (83,906) | (153,003) | ||
| Loss from operations | (29,888) | (3,345) | (59,544) | (71,859) | ||
| Non-cash interest expense related to the sale of future royalties | (9,862) | (9,647) | (19,329) | (18,991) | ||
| Interest income | 1,723 | 2,519 | 3,358 | 5,708 | ||
| Interest and other income (expense), net | (505) | (1,044) | (1,516) | (2,336) | ||
| Loss before provision for income taxes | (38,532) | (11,517) | (77,031) | (87,478) | ||
| Income tax benefits (expense) | (1) | 18 | 14 | 11 | ||
| Net loss | (38,533) | $ (38,484) | (11,499) | $ (75,968) | (77,017) | (87,467) |
| Operating Segment | ||||||
| Segment Reporting Information [Line Items] | ||||||
| Revenue | 9,839 | 63,745 | 24,362 | 81,144 | ||
| Personnel-related expenses | (12,776) | (21,823) | (26,713) | (48,793) | ||
| Outside services | (17,194) | (16,369) | (39,269) | (35,747) | ||
| Preclinical research and clinical development expenses | (2,651) | 1,356 | (3,896) | (4,599) | ||
| Laboratory supplies | (722) | (3,397) | (1,335) | (7,556) | ||
| Facility and maintenance expenses | (2,934) | (3,818) | (5,994) | (7,253) | ||
| Equipment and office-related expenses | (3,089) | (4,388) | (6,182) | (9,114) | ||
| Travel-related expenses | (160) | (229) | (274) | (476) | ||
| Restructuring and related costs | (201) | (18,422) | (243) | (39,465) | ||
| Operating expenses | (39,727) | (67,090) | (83,906) | (153,003) | ||
| Loss from operations | (29,888) | (3,345) | (59,544) | (71,859) | ||
| Non-cash interest expense related to the sale of future royalties | (9,862) | (9,647) | (19,329) | (18,991) | ||
| Interest income | 1,723 | 2,519 | 3,358 | 5,708 | ||
| Interest and other income (expense), net | (505) | (1,044) | (1,516) | (2,336) | ||
| Non-operating loss | (8,644) | (8,172) | (17,487) | (15,619) | ||
| Loss before provision for income taxes | (38,532) | (11,517) | (77,031) | (87,478) | ||
| Income tax benefits (expense) | (1) | 18 | 14 | 11 | ||
| Net loss | $ (38,533) | $ (11,499) | $ (77,017) | $ (87,467) | ||
| X | ||||||||||
- Definition Equipment and office related expenses. No definition available.
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- Definition Facility and maintenance expenses. No definition available.
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- Definition Interest and other income (expense), net. No definition available.
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- Definition Laboratory supplies. No definition available.
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- Definition Non-cash interest expense related to the sale of future royalties. No definition available.
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- Definition Outside services. No definition available.
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- Definition Preclinical research and clinical development expenses. No definition available.
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- Definition Travel related expenses. No definition available.
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- Definition Amount of income (loss) from continuing operations, including income (loss) from equity method investments, before deduction of income tax expense (benefit), and income (loss) attributable to noncontrolling interest. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate amount of income from investments (for example, dividends) not considered a component of the entity's core operations. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount of expense for salary, wage, profit sharing; incentive and equity-based compensation; and other employee benefit. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The aggregate amount of income or expense from ancillary business-related activities (that is to say, excluding major activities considered part of the normal operations of the business). Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Generally recurring costs associated with normal operations except for the portion of these expenses which can be clearly related to production and included in cost of sales or services. Includes selling, general and administrative expense. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition The net result for the period of deducting operating expenses from operating revenues. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Amount, after cash payment, of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation. Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. Reference 1: http://www.xbrl.org/2003/role/exampleRef
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. No definition available.
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- Details
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