Restructuring and Related Costs (Tables)

6 Months Ended

Jun. 30, 2026

Restructuring and Related Activities [Abstract]

Summary of Restructuring and Related Costs

Total restructuring and related costs from the Restructuring Plans include the following:


		Three Months Ended								Six Months Ended
		June 30, 2026				June 30, 2025				June 30, 2026				June 30, 2025
		(in thousands)								(in thousands)
Clinical trial expense and other third-party costs for the deprioritization of the luvelta program		$	201			$	13,006			$	243			$	17,261
Severance and benefits expense			—				3,862				—				12,372
Contract termination and other restructuring costs			—				1,554				—				9,832
Total		$	201			$	18,422			$	243			$	39,465

Summary of Severance and Other Termination Benefit Expense and Reconciliation of Such Liability

The following table provides details regarding the severance and other termination benefit expense and a reconciliation of such liability for the six months ended June 30, 2026, which is reported within accrued compensation on the condensed Balance Sheet:


		June 30, 2026
		(in thousands)
Liability balance as of December 31, 2025		$	2,847
Payments during the period			(2,572	)
Liability balance as of June 30, 2026		$	275

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