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Commitments, Contingencies, and Collaborations - Allist (Details) - USD ($) $ in Thousands		3 Months Ended		6 Months Ended		61 Months Ended
	Jun. 30, 2021	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026	Jun. 30, 2025	Jun. 30, 2026
Agreement
Research and development		$ 42,339	$ 27,720	$ 79,957	$ 89,009
Global Technology Transfer And License Agreement \| Allist
Agreement
Cash payment	$ 40,000
Maximum amount payable upon achievement of certain clinical and regulatory milestone events	110,000
Maximum amount payable upon achievement of commercial milestones	$ 655,000
Global Technology Transfer And License Agreement \| Allist \| Common stock
Agreement
Shares issued in execution of agreement (in shares)	1,276,250
Clinical Collaboration Agreement \| Allist
Agreement
Research and development		1,500	100	1,900	600
Cost reimbursement		$ 400	$ 200	$ 700	$ 600
Milestone payments paid						$ 10,000