June 30,

December 31,

2026

2025

Stock options outstanding

20,349,469

16,004,393

Pre-Funded Warrants outstanding

62,246,707

73,011,767

Shares available for future grant under the 2021 equity incentive plan

8,283,482

7,432,023

Shares available for future issuance under the 2021 employee stock purchase plan

1,771,927

1,316,566

Total shares of common stock reserved

92,651,585

97,764,749