v3.26.1
Segment Information - Schedule of Reportable Segment Net Revenues and Loss (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Revenues:        
Revenue, Product and Service [Extensible Enumeration] us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember
Total revenues $ 0 $ 14,189 $ 258 $ 20,063
Less:        
Research and development 3,434 10,672 6,343 24,278
General and administrative 6,492 5,878 11,379 12,702
Other segment items [1] 3 79 4 253
Interest income (377) (740) (713) (1,604)
Consolidated loss (9,552) (1,700) (16,755) (15,566)
Grant Revenue        
Revenues:        
Total revenues 0 2,387 0 3,150
Collaboration revenue - related party        
Revenues:        
Total revenues 0 11,802 258 16,901
Collaboration revenue        
Revenues:        
Total revenues 0 0 0 12
Tebipenem HBr        
Less:        
Research and development 1,298 6,694 1,710 15,363
SPR720        
Less:        
Research and development 0 349 0 797
SPR206        
Less:        
Research and development 0 0 0 49
Research and development personnel related (including share-based compensation)        
Less:        
Research and development 1,349 2,611 3,018 5,948
Facility related and other        
Less:        
Research and development 787 1,018 1,615 2,121
General and administrative 539 524 1,456 967
General and administrative personnel related (including share-based compensation)        
Less:        
General and administrative 1,793 3,368 4,082 7,486
Professional and consultant fees        
Less:        
General and administrative $ 4,160 $ 1,986 $ 5,841 $ 4,249
[1] Other segment items include restructuring charges and other income, net.