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  <xs:element id="zura_TemporaryEquityDisclosureAndStockholdersEquityNoteDisclosureTextBlock" abstract="false" name="TemporaryEquityDisclosureAndStockholdersEquityNoteDisclosureTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="zura_SignificantOfAccountingPoliciesTextBlock" abstract="false" name="SignificantOfAccountingPoliciesTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="zura_RisksAndUncertaintiesPolicyPolicyTextBlock" abstract="false" name="RisksAndUncertaintiesPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="zura_ResearchAndDevelopmentIncentiveCreditsPolicyTextBlock" abstract="false" name="ResearchAndDevelopmentIncentiveCreditsPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="zura_SummaryOfSharesReservedForIssuanceTableTextBlock" abstract="false" name="SummaryOfSharesReservedForIssuanceTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="zura_EquityIncentivePlan2023Member" abstract="true" name="EquityIncentivePlan2023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_ResearchAndDevelopmentIncentiveCreditsNumberOfClaimsFiled" abstract="false" name="ResearchAndDevelopmentIncentiveCreditsNumberOfClaimsFiled" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="zura_ResearchAndDevelopmentIncentiveCreditsPendingClaimAmount" abstract="false" name="ResearchAndDevelopmentIncentiveCreditsPendingClaimAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_ReportableSegmentMember" abstract="true" name="ReportableSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_TibulizumabSScProgramMember" abstract="true" name="TibulizumabSScProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_TibulizumabHSProgramMember" abstract="true" name="TibulizumabHSProgramMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_TibulizumabProgramGeneralMember" abstract="true" name="TibulizumabProgramGeneralMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AdditionalProductCandidatesMember" abstract="true" name="AdditionalProductCandidatesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_ResearchAndDevelopmentExpenseUnallocatedExpense" abstract="false" name="ResearchAndDevelopmentExpenseUnallocatedExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_ShareBasedPaymentArrangementNoncashExpenseAdjusted" abstract="false" name="ShareBasedPaymentArrangementNoncashExpenseAdjusted" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_Z33SeriesSeedPreferredSharesPutRightMember" abstract="true" name="Z33SeriesSeedPreferredSharesPutRightMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AccruedResearchAndDevelopmentExpenseCurrent" abstract="false" name="AccruedResearchAndDevelopmentExpenseCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_AccruedBonusCostCurrent" abstract="false" name="AccruedBonusCostCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_Baffx17LtdMember" abstract="true" name="Baffx17LtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_LicenseAgreementWithLillyMember" abstract="true" name="LicenseAgreementWithLillyMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_StonePeachPropertiesLlcMember" abstract="true" name="StonePeachPropertiesLlcMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AssetAcquisitionConsiderationNumberOfDevelopmentAndRegulatoryMilestonePayments" abstract="false" name="AssetAcquisitionConsiderationNumberOfDevelopmentAndRegulatoryMilestonePayments" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="zura_AssetAcquisitionConsiderationMaximumDevelopmentAndRegulatoryMilestonePaymentsBasedOnRespectiveThresholdsOfNetSalesOfProducts" abstract="false" name="AssetAcquisitionConsiderationMaximumDevelopmentAndRegulatoryMilestonePaymentsBasedOnRespectiveThresholdsOfNetSalesOfProducts" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_AssetAcquisitionConsiderationMaximumSalesMilestonePaymentsBasedOnRespectiveThresholdsOfNetSalesOfProducts" abstract="false" name="AssetAcquisitionConsiderationMaximumSalesMilestonePaymentsBasedOnRespectiveThresholdsOfNetSalesOfProducts" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_PeriodForPaymentOfMilestonePayment" abstract="false" name="PeriodForPaymentOfMilestonePayment" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="zura_ContingentPaymentDue" abstract="false" name="ContingentPaymentDue" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_LicenseAgreementAndSeriesA1SubscriptionAndShareholdersAgreementWithPfizerMember" abstract="true" name="LicenseAgreementAndSeriesA1SubscriptionAndShareholdersAgreementWithPfizerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_LonzaLicenseAgreementMember" abstract="true" name="LonzaLicenseAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_WuxiBiologicsLicenseMember" abstract="true" name="WuxiBiologicsLicenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AthanorLetterAgreementMember" abstract="true" name="AthanorLetterAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AnthorMember" abstract="true" name="AnthorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_AssetAcquisitionConsiderationMaximumPercentageOfPaymentOfAnnualEarnedRoyaltyAtMarginalRoyaltyRate" abstract="false" name="AssetAcquisitionConsiderationMaximumPercentageOfPaymentOfAnnualEarnedRoyaltyAtMarginalRoyaltyRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="zura_AnnualMilestonePaymentDueAndPayable" abstract="false" name="AnnualMilestonePaymentDueAndPayable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_AccruedLicenseCosts" abstract="false" name="AccruedLicenseCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_MilestonePaymentUpfrontFee" abstract="false" name="MilestonePaymentUpfrontFee" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_UpfrontFeePaymentPeriod" abstract="false" name="UpfrontFeePaymentPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="zura_OneTimeMilestonePaymentOnAchievementOfConditions" abstract="false" name="OneTimeMilestonePaymentOnAchievementOfConditions" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_MinimumNetProceedsFromSaleOfAssetsForOneTimeMilestonePayment" abstract="false" name="MinimumNetProceedsFromSaleOfAssetsForOneTimeMilestonePayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_PaymentForTheProductOnNetSalesPercentage" abstract="false" name="PaymentForTheProductOnNetSalesPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="zura_CapitalSharesReservedForFutureIssuanceAmount" abstract="false" name="CapitalSharesReservedForFutureIssuanceAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="zura_ThresholdPercentageOfOutstandingSharesOwned" abstract="false" name="ThresholdPercentageOfOutstandingSharesOwned" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="zura_ThresholdPercentageOfOutstandingSharesOwnedShareholderElectionUponWrittenNotice" abstract="false" name="ThresholdPercentageOfOutstandingSharesOwnedShareholderElectionUponWrittenNotice" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="zura_ClassOfWarrantOrRightThresholdNoticePeriod" abstract="false" name="ClassOfWarrantOrRightThresholdNoticePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="zura_EquityIncentivePlan2023AndEmployeeStockPurchasePlan2023Member" abstract="true" name="EquityIncentivePlan2023AndEmployeeStockPurchasePlan2023Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_EmployeeStockPurchasePlanMember" abstract="true" name="EmployeeStockPurchasePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_OutsideOfEquityIncentivePlanMember" abstract="true" name="OutsideOfEquityIncentivePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_MarketBasedPerformanceShareOptionsMember" abstract="true" name="MarketBasedPerformanceShareOptionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_DirectorsExecutivesAndEmployeesMember" abstract="true" name="DirectorsExecutivesAndEmployeesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="zura_CommonStockDiscountOnSharesPercentage" abstract="false" name="CommonStockDiscountOnSharesPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="zura_ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageExercisePriceThresholdConsecutiveTradingDays" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageExercisePriceThresholdConsecutiveTradingDays" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="zura_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsSharePrice" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsSharePrice" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:decimalItemType"/>
  <xs:element id="zura_ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageRemainingContractualLifeAbstract" abstract="true" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardWeightedAverageRemainingContractualLifeAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="zura_ShareBasedCompensationArrangementByShareBasedPaymentAwardAggregateIntrinsicValueAbstract" abstract="true" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAggregateIntrinsicValueAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
</xs:schema>
