| Summary of Selected Financial Information with Respect to Operating Segment |
The following table presents selected financial information with respect to the Company’s single operating segment for the three and six months ended June 30, 2026 and 2025 (amounts in thousands):
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Three Months Ended June 30, |
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Six Months Ended June 30, |
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2026 |
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2025 |
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2026 |
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2025 |
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License revenue |
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$ |
— |
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$ |
— |
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$ |
20,000 |
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$ |
— |
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Direct external research and development expenses by program: |
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MZE829 |
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8,444 |
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5,199 |
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15,540 |
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9,823 |
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MZE782 |
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3,177 |
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4,582 |
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8,471 |
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8,948 |
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Discovery research and other programs |
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3,596 |
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2,742 |
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6,641 |
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5,752 |
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Internal research and development expenses: |
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Personnel-related |
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14,875 |
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10,609 |
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28,866 |
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20,953 |
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Facilities, lab supplies and other |
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4,848 |
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4,976 |
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9,570 |
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10,212 |
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Total research and development expenses |
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34,940 |
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28,108 |
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69,088 |
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55,688 |
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General and administrative expenses |
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13,095 |
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8,366 |
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25,500 |
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16,187 |
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Segment operating expenses |
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48,035 |
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36,474 |
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94,588 |
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71,875 |
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Segment loss from operations |
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(48,035 |
) |
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(36,474 |
) |
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(74,588 |
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(71,875 |
) |
Segment other income, net |
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3,308 |
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2,795 |
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5,653 |
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5,410 |
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Segment loss |
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$ |
(44,727 |
) |
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$ |
(33,679 |
) |
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$ |
(68,935 |
) |
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$ |
(66,465 |
) |
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