Property and equipment, net, consist of the following (in thousands):


	June 30, 2026			December 31, 2025
Laboratory equipment	$	3,441		$	7,888
Office equipment		386			386
Leasehold improvements		358			358
Total property and equipment		4,185			8,632
Less accumulated depreciation and amortization		(3,614	)		(7,387	)
Total	$	571		$	1,245

Depreciation expense related to property and equipment was $0.2 million and $0.3 million for the three months ended June 30, 2026 and 2025, respectively, and $0.4 million and $0.7 million for the six months ended June 30, 2026 and 2025, respectively.

During the three months ended June 30, 2026, the Company sold certain laboratory equipment for proceeds of $0.7 million and recognized a gain on disposal of $0.4 million. There was no laboratory equipment sold during the three months ended June 30, 2025.

During the six months ended June 30, 2026, the Company sold certain laboratory equipment for proceeds of $0.7 million and recognized a gain on disposal of $0.4 million. During the six months ended June 30, 2025, the Company sold certain laboratory equipment for proceeds of $1.0 million and recognized a gain on disposal of $0.3 million.

Accrued expenses and other current liabilities consist of the following (in thousands):


	June 30, 2026		December 31, 2025
Accrued research and development	$	1,257	$	1,043
Accrued compensation		1,241		1,642
Accrued restructuring charges		28		744
Accrued other		563		288
Total	$	3,089	$	3,717