S-8 S-8 EX-FILING FEES 0001680367 Shattuck Labs, Inc. N/A Fees to be Paid Fees to be Paid 0001680367 2026-08-10 2026-08-10 0001680367 1 2026-08-10 2026-08-10 0001680367 2 2026-08-10 2026-08-10 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-8

Shattuck Labs, Inc.

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee Calculation Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

1 Equity Common Stock, par value $0.0001 per share ("Common Stock") to be issued pursuant to the Shattuck Labs, Inc. Amended and Restated 2020 Equity Incentive Plan (the "Plan") 457(a) 4,222,276 $ 7.37 $ 31,118,174.12 0.0001381 $ 4,297.42
2 Equity Common Stock to be issued pursuant to Inducement Nonstatutory Stock Options (the "Options") 457(a) 206,000 $ 3.23 $ 665,380.00 0.0001381 $ 91.89

Total Offering Amounts:

$ 31,783,554.12

$ 4,389.31

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 4,389.31

Offering Note

1

1. Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional shares of Common Stock that may become issuable under the Plan as a result of any stock dividend, stock split, recapitalization or other similar transaction, and any other securities with respect to which the outstanding shares are converted or exchanged. The "Proposed Maximum Offering Price Per Unit" and the "Maximum Aggregate Offering Price" are estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and (h) under the Securities Act and are based on the average of the high and low sale prices of the Registrant's Common Stock, as quoted on the Nasdaq Global Select Market, on August 6, 2026. 2. Pursuant to Rule 416(a) under the Securities Act, this Registration Statement shall also cover any additional shares of Common Stock that may become issuable under the Options as a result of any stock dividend, stock split, recapitalization or other similar transaction, and any other securities with respect to which the outstanding shares are converted or exchanged. The "Proposed Maximum Offering Price Per Unit" and the "Maximum Aggregate Offering Price" the purpose of calculating the registration fee pursuant to Rule 457(h) under the Securities Act is based on the applicable exercise price of the Options.

2

1. Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional shares of Common Stock that may become issuable under the Plan as a result of any stock dividend, stock split, recapitalization or other similar transaction, and any other securities with respect to which the outstanding shares are converted or exchanged. The "Proposed Maximum Offering Price Per Unit" and the "Maximum Aggregate Offering Price" are estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and (h) under the Securities Act and are based on the average of the high and low sale prices of the Registrant's Common Stock, as quoted on the Nasdaq Global Select Market, on August 6, 2026. 2. Pursuant to Rule 416(a) under the Securities Act, this Registration Statement shall also cover any additional shares of Common Stock that may become issuable under the Options as a result of any stock dividend, stock split, recapitalization or other similar transaction, and any other securities with respect to which the outstanding shares are converted or exchanged. The "Proposed Maximum Offering Price Per Unit" and the "Maximum Aggregate Offering Price" the purpose of calculating the registration fee pursuant to Rule 457(h) under the Securities Act is based on the applicable exercise price of the Options.
Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rule 457(p)
Fee Offset Claims
Fee Offset Sources