Trading Arrangements, by Individual
Trading Arrangements, by Individual [Table]
Trading Arrangement:
Trading Arrangement [Axis]
Weighted average remaining contractual term, ending balance (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted-Average Remaining Contractual Term
Maximum
Maximum [Member]
Range [Domain]
Statistical Measurement [Domain]
Title of 12(b) Security
Title of 12(b) Security
Subsequent Event
Subsequent Event [Member]
Document Fiscal Year Focus
Document Fiscal Year Focus
Adjustment to Compensation, Amount
Adjustment to Compensation Amount
Segment Reporting [Abstract]
Common stock, $0.0001 par value; 500,000,000 shares authorized as of June 30, 2026 and December 31, 2025, and 13,644,467 and 12,038,263 shares issued and outstanding as of June 30, 2026 and December 31, 2025, respectively
Common Stock, Value, Issued
2027
Lessee, Operating Lease, Liability, to be Paid, Year One
Fair value of stock options granted and change in fair value of shares subject to shares available liability
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease)
Restatement Determination Date
Restatement Determination Date
Class of Warrant or Right [Domain]
Class of Warrant or Right [Domain]
Warrant exercised (in shares)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Closing bid price (in dollars per share)
Debt Instrument, Convertible, Conversion Price
Consecutive trading days period (in days)
Class of Warrant or Right, Exercise Price of Warrants or Rights, Consecutive Trading Day Period
Class of Warrant or Right, Exercise Price of Warrants or Rights, Consecutive Trading Day Period
Amendment Flag
Amendment Flag
Current liabilities:
Liabilities, Current [Abstract]
Other
Other Sundry Liabilities, Current
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Monthly retainer services amount
Salary And Wage, Officer, Monthly Retainer Services Amount
Salary And Wage, Officer, Monthly Retainer Services Amount
Time based Stock Appreciation Rights
Time based Stock Appreciation Rights [Member]
Time based Stock Appreciation Rights
February 2026 common warrants
Shares reserved for the February 2026 common warrants
February 2026 Common Warrants [Member]
February 2026 Common Warrants
Total long-term liabilities
Liabilities, Noncurrent
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Other
Accounts Payable, Other, Current
Adjustment to Non-PEO NEO Compensation Footnote
Adjustment to Non-PEO NEO Compensation Footnote [Text Block]
Securities Purchase Agreement
Securities Purchase Agreement [Member]
Securities Purchase Agreement
Entity Address, State or Province
Entity Address, State or Province
Granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Foreign currency translation
Foreign exchange translation adjustment
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent
PEO Total Compensation Amount
PEO Total Compensation Amount
Common stock, par value (in usd per share)
Common Stock, Par or Stated Value Per Share
Assets
Assets, Fair Value Disclosure [Abstract]
Long term liabilities
Liabilities, Noncurrent [Abstract]
Weighted-average common shares outstanding, basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Outstanding Aggregate Erroneous Compensation Amount
Outstanding Aggregate Erroneous Compensation Amount
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Number of reportable segments
Number of Reportable Segments
Total current liabilities
Liabilities, Current
May 2025 Series B Warrants
May 2025 Series B Warrants [Member]
May 2025 Series B Warrants
Entity Address, City or Town
Entity Address, City or Town
Reimbursement of effective period
Salary and Wage, Reimbursement Effective Period
Salary and Wage, Reimbursement Effective Period
Shares issued under the ESPP (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Statement of Financial Position [Abstract]
Statement of Financial Position [Abstract]
Lump-sum payment, bonus (as a percent)
Salary and Wage, Lump-Sum Bonus Payment, Percentage
Salary and Wage, Lump-Sum Bonus Payment, Percentage
Relationship to Entity [Domain]
Title and Position [Domain]
Award Timing MNPI Disclosure
Award Timing MNPI Disclosure [Text Block]
Basis of Presentation and Consolidation
Basis of Accounting, Policy [Policy Text Block]
Peer Group Total Shareholder Return Amount
Peer Group Total Shareholder Return Amount
Level 2
Fair Value, Inputs, Level 2 [Member]
Other income (expense):
Nonoperating Income (Expense) [Abstract]
Total Shareholder Return Vs Peer Group
Total Shareholder Return Vs Peer Group [Text Block]
Planegg, Germany
Planegg, Germany [Member]
Planegg, Germany
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated [Flag]
Board of Directors Chairman
Board of Directors Chairman [Member]
Offering
Offering [Member]
Offering
Investment interest rate (as a percent)
Investment Interest Rate
United States
UNITED STATES
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Impairment of Long-Lived Assets
Long-Lived Asset, Excluding Intangible Asset and Goodwill, Impairment and Disposal [Policy Text Block]
Recently Issued and/or Adopted Accounting Standards
New Accounting Pronouncements, Policy [Policy Text Block]
Net Loss Per Share
Earnings Per Share, Policy [Policy Text Block]
Schedule of Significant Expense
Segment Reporting [Table Text Block]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Related Party [Axis]
Related and Nonrelated Parties [Axis]
Schedule of Fair Value of Tranche Rights
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Exercise price (in usd per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Proceeds from offering, net of issuance costs
Proceeds from Debt, Net of Issuance Costs
Schedule of Maturities of Operating Lease Obligation
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Document Period End Date
Document Period End Date
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Forfeited or expired (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period
Net cash used in investing activities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Equity Awards Adjustments, Excluding Value Reported in Compensation Table
Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member]
Preferred stock, shares outstanding (in shares)
Preferred Stock, Shares Outstanding
2028
Lessee, Operating Lease, Liability, to be Paid, Year Two
Common Stock
Equity [Text Block]
Security Exchange Name
Security Exchange Name
Lessee Disclosure [Abstract]
Granted (in usd per share)
SARs granted (usd per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Leases [Line Items]
Lessee, Lease, Description [Line Items]
Accrued legal and audit costs
Accrued Legal And Audit Costs, Current
Accrued Legal And Audit Costs, Current
Total Liabilities
Liabilities, Fair Value Disclosure
Accumulated other comprehensive income
Accumulated Other Comprehensive Income (Loss), Net of Tax
Entity Shell Company
Entity Shell Company
Authorized (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Lease liabilities
Operating Lease, Liability, Current
Schedule of Shares Reserved for Future Issuance
Schedule Of Common Stock Reserved For Future Issuance [Table Text Block]
Schedule Of Common Stock Reserved For Future Issuance [Table Text Block]
Additional shares authorized (as a percent)
Share-based Compensation Arrangement By Share-Based Payment Award, Additional Shares Authorized, Percent
Share-based Compensation Arrangement By Share-Based Payment Award, Additional Shares Authorized, Percent
Statement of Comprehensive Income [Abstract]
Statement of Comprehensive Income [Abstract]
May 2025 Pre-Funded Warrants Offering
May 2025 Pre-Funded Warrants Offering [Member]
May 2025 Pre-Funded Warrants Offering
Name
Outstanding Recovery, Individual Name
Award Timing, How MNPI Considered
Award Timing, How MNPI Considered [Text Block]
Document Fiscal Period Focus
Document Fiscal Period Focus
Peer Group Issuers, Footnote
Peer Group Issuers, Footnote [Text Block]
Shares exercised from pre-funded warrants (in shares)
SARs exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Exercised
Clinical product candidates
Clinical Product Candidates
Clinical Product Candidates
Total liabilities
Liabilities
Trading Symbol
Trading Symbol
Accrued compensation
Accrued Compensation, Current
Accrued Compensation, Current
January 2024 Pre-Funded Warrants
Shares reserved for the January 2024 Pre-funded stock warrants
January 2024 Pre-Funded Warrants [Member]
January Pre-Funded Warrants
Geographical [Domain]
Geographical [Domain]
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year
Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member]
Pension Adjustments Prior Service Cost
Pension Adjustments Prior Service Cost [Member]
Number of tranches
Share-Based Compensation Arrangement By Share-Based Payment Award, Number Of Tranches
Share-Based Compensation Arrangement By Share-Based Payment Award, Number Of Tranches
New York City
New York City [Member]
New York City
Company Selected Measure Name
Company Selected Measure Name
Placement agent warrants
Placement Agent Warrants [Member]
Placement Agent Warrants
Sale of Stock [Domain]
Sale of Stock [Domain]
Aggregate salary
Salary and Wage, Officer, Aggregate Salary
Salary and Wage, Officer, Aggregate Salary
Supplemental disclosure of noncash investing and financing activities:
Noncash Investing and Financing Items [Abstract]
Depreciation expense
Depreciation, Depletion and Amortization, Nonproduction
Related Party Transactions [Abstract]
Related Party Transactions [Abstract]
Compensation Amount
Outstanding Recovery Compensation Amount
Individual:
Individual [Axis]
Weighted-average common shares outstanding, diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Common stock, cash dividends declared (in usd per share)
Common Stock, Dividends, Per Share, Cash Paid
Stock Appreciation Rights from exercised Series B Warrants
Stock Appreciation Rights from exercised Series B Warrants [Member]
Stock Appreciation Rights from exercised Series B Warrants
Entity Emerging Growth Company
Entity Emerging Growth Company
Equity Valuation Assumption Difference, Footnote
Equity Valuation Assumption Difference, Footnote [Text Block]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Estimated useful life (in years)
Property, Plant, and Equipment, Useful Life
Schedule of Other Current Assets and Prepaid Expenses
Schedule of Other Current Assets [Table Text Block]
Underlying Security Market Price Change
Underlying Security Market Price Change, Percent
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Expiration period from the date of issuance (in years)
Class of Warrant or Right, Expiration Period From The Date Of Issuance
Class of Warrant or Right, Expiration Period From The Date Of Issuance
Interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Purchase price of the stock, at discount from market price at purchase date (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Discount from Market Price, Purchase Date
February 2026 Pre-Funded warrants
February 2026 Pre-Funded Warrants [Member]
February 2026 Pre-Funded Warrants
Award Timing Predetermined
Award Timing Predetermined [Flag]
Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Royalty Purchase Agreement
Royalty Purchase Agreement [Member]
Royalty Purchase Agreement
Adjustment To PEO Compensation, Footnote
Adjustment To PEO Compensation, Footnote [Text Block]
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Level 1
Fair Value, Inputs, Level 1 [Member]
Proceeds from Warrant Exercises
Proceeds from Warrant Exercises
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Common stock options available for future grant:
Employee Stock Options for Future Grant [Member]
Employee Stock Options for Future Grant [Member]
Total
Lessee, Operating Lease, Liability, to be Paid
Fair Value Measurement
Fair Value of Financial Instruments, Policy [Policy Text Block]
Grant-date fair value (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
All Executive Categories
All Executive Categories [Member]
Chief Executive Officer
Chief Executive Officer [Member]
Operating lease liability
Increase (Decrease) in Operating Lease Liability
Pension Adjustments Service Cost
Pension Adjustments Service Cost [Member]
Other comprehensive income (loss):
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract]
Preferred stock, par value (in usd per share)
Preferred Stock, Par or Stated Value Per Share
Vesting [Domain]
Vesting [Domain]
Plan Name [Domain]
Plan Name [Domain]
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward]
Outstanding, beginning balance (in usd per share)
Outstanding, ending balance (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Impairment losses
Tangible Asset Impairment Charges
Increase in other share (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Other Share Increase (Decrease)
Right-of-use assets
Operating Lease, Right-of-Use Asset
Reimbursement of legal fees
Legal Fees
Placement agent agreement, cash fee, percent of gross proceeds from offering (as a percent)
Placement Agent Agreement, Brokerage Fee, Percent
Placement Agent Agreement, Brokerage Fee, Percent
Series A Warrants
Series A Warrants [Member]
Series A Warrants
Renewal option period (in months)
Lessee, Operating Lease, Renewal Term
Fair Value Disclosures [Abstract]
Fair Value Disclosures [Abstract]
Risk-free interest rate, maximum (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Segment Disclosures
Segment Reporting [Text Block]
Minimum
Minimum [Member]
Expiration Date
Trading Arrangement Expiration Date
Australian research and development tax incentive
Government Assistance, Qualified Research and Development Expenditures, Maximum Amount
Government Assistance, Qualified Research and Development Expenditures, Maximum Amount
June 2025 PIPE Transaction
June 2025 P I P E Transaction [Member]
June 2025 P I P E Transaction
Liabilities [Abstract]
Liabilities [Abstract]
Class of Warrant or Right [Axis]
Class of Warrant or Right [Axis]
Monthly base salary
Salary and Wage, Officer, Monthly Base Salary
Salary and Wage, Officer, Monthly Base Salary
Effect of exchange rate changes on cash and cash equivalents
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Income Statement Location [Axis]
Location, Statement of Income, Balance [Axis]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted [Flag]
Money market funds
Cash and Cash Equivalents, Fair Value Disclosure
Outstanding, Weighted-Average Remaining Contractual Term, Ending balance (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted-Average Remaining Contractual Term
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table
Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member]
Non-statutory options
Non-Statutory Employee Stock Option [Member]
Non-Statutory Employee Stock Option [Member]
Options exercisable, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Issuance costs
Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs
Aggregate Pension Adjustments Service Cost
Aggregate Pension Adjustments Service Cost [Member]
Initial exercise price per share (as a percent)
Sale of Stock, Percentage of Ownership after Transaction
Proceeds from Issuance of Common Stock
Proceeds from Issuance of Common Stock
Series B Warrants
Series B Warrants [Member]
Series B Warrants
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Exercisable, aggregate intrinsic value, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Shares issues in private placement transaction (in shares)
Sale of Stock, Number of Shares Issued in Transaction
Nature of Operation, Product Information, Concentration of Risk [Table]
Nature of Operation, Product Information, Concentration of Risk [Table]
Exercise Price
Award Exercise Price
Related Party Transaction [Axis]
Related Party Transaction [Axis]
Segment Reporting [Line Items]
Segment Reporting [Line Items]
Total unrecognized compensation expense
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Document Quarterly Report
Document Quarterly Report
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested
Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member]
Segments [Domain]
Segments [Domain]
2021 Employee stock purchase plan
2021 Employee Stock Purchase Plan [Member]
2021 Employee Stock Purchase Plan
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Property and Equipment
Property, Plant, and Equipment [Policy Text Block]
Contractual obligation
Contractual Obligation
Duane Nash, MD, JD, MBA
Duane Nash, MD, JD, MBA [Member]
Duane Nash, MD, JD, MBA
Shares reserved for SARs for exercised Series B warrants
Exercised Series B warrants [Member]
Exercised Series B warrants
Awards Close in Time to MNPI Disclosures, Table
Awards Close in Time to MNPI Disclosures [Table Text Block]
Equity Component [Domain]
Equity Component [Domain]
PEO Actually Paid Compensation Amount
PEO Actually Paid Compensation Amount
Shares sold in the offering (as a percent)
Sale of Stock, Percentage of Ownership before Transaction
Consideration received on transaction
Sale of Stock, Consideration Received on Transaction
Shares reserved for the January 2024 Pre-funded stock warrants
Pre-Funded Warrants [Member]
Pre-Funded Warrants
Adoption Date
Trading Arrangement Adoption Date
Research grant receivable
Research and Development Grant
Research and Development Grant
SARs liability
Deferred Compensation Share-Based Arrangements, Liability, Current and Noncurrent
Counterparty Name [Domain]
Counterparty Name [Domain]
Total stockholders’ equity (deficit)
Beginning balance
Ending balance
Equity, Attributable to Parent
Total other income
Nonoperating Income (Expense)
Prepaid insurance
Prepaid Insurance
Outstanding equity awards vested (as a percent)
Salary and Wage, Outstanding Equity Awards Vested, Percentage
Salary and Wage, Outstanding Equity Awards Vested, Percentage
Assets
Assets [Abstract]
Title
Trading Arrangement, Individual Title
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Forgone Recovery due to Disqualification of Tax Benefits, Amount
Accounting Policies [Abstract]
Accounting Policies [Abstract]
Restatement does not require Recovery
Restatement Does Not Require Recovery [Text Block]
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Present value of obligation
Operating Lease, Liability
Professional fees and other segment expenses
Professional Fees
Issuance costs
Payments of Stock Issuance Costs
Insider Trading Policies and Procedures [Line Items]
Outstanding, beginning balance (in shares)
Outstanding, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Reclassification of the fair value of SARs liability to equity
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, No Longer Subject To Shares
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, No Longer Subject To Shares
Insider Trading Policies and Procedures Adopted
Insider Trading Policies and Procedures Adopted [Flag]
Other current assets and prepaid expenses
Total
Prepaid Expense and Other Assets, Current
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Balance Sheet Details
Supplemental Balance Sheet Disclosures [Text Block]
Forfeited or expired (in usd per share)
SARs forfeited or expired (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Compensation Actually Paid vs. Net Income
Compensation Actually Paid vs. Net Income [Text Block]
Options to purchase common stock ( in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Schedule of Potentially Dilutive Securities Not Included in Calculation of Diluted Net Loss per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Entity Central Index Key
Entity Central Index Key
All Adjustments to Compensation
All Adjustments to Compensation [Member]
Equity [Abstract]
Equity [Abstract]
Proceeds from issuance of private placement
Proceeds from Issuance of Private Placement
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year
Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member]
Income Taxes
Income Tax, Policy [Policy Text Block]
Net cash used in operating activities
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Income Statement [Abstract]
Income Statement [Abstract]
Stockholders’ equity (deficit):
Equity, Attributable to Parent [Abstract]
Shares issued in connection with the Company's employee stock purchase plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Document Transition Report
Document Transition Report
Unsold securities to be sold under shelf registration
Unsold Securities Rolled Over To Be Sold Under New Shelf Registration
Unsold Securities Rolled Over To Be Sold Under New Shelf Registration
Legal and audit costs
Legal And Audit Costs Payable, Current
Legal And Audit Costs Payable, Current
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Operating expenses:
Operating expenses:
Operating Expenses [Abstract]
2019 Omnibus Equity Incentive Plan And 2026 Inducement Plan
2019 Omnibus Equity Incentive Plan And 2026 Inducement Plan [Member]
2019 Omnibus Equity Incentive Plan And 2026 Inducement Plan
SARs liability
Stock Appreciation Rights (SARs)
Stock Appreciation Rights (SARs) [Member]
Probability, not occurring (as a percent)
Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Probability Rate, Liquidation Event Not Occurring Estimated
Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Probability Rate, Liquidation Event Not Occurring Estimated
Schedule of Valuation Assumptions Used
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Number of installments
Number Of Installments
Number Of Installments
Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Stock options remaining (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Remaining Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Remaining Shares
City Area Code
City Area Code
Accumulated Other Comprehensive Income
AOCI Attributable to Parent [Member]
All Individuals
All Individuals [Member]
Subsequent Events
Subsequent Events [Text Block]
Name
Forgone Recovery, Individual Name
Period over which compensation cost will be recognized (in years)
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Non-GAAP Measure Description
Non-GAAP Measure Description [Text Block]
Weighted average exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Statement [Line Items]
Statement [Line Items]
Total assets
Assets
Incremental borrowing rate on operating leases (as a percent)
Operating Lease, Incremental Borrowing Rate
Operating Lease, Incremental Borrowing Rate
Reimbursement of healthcare costs
Healthcare Costs
Healthcare Costs
Weighted average remaining contractual term (years) and Aggregate intrinsic value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract]
Government assistance, income
Government Assistance, Income, Increase (Decrease)
Preferred stock, shares issued (in shares)
Preferred Stock, Shares Issued
Total common shares reserved for future issuance (in shares)
Common Stock, Capital Shares Reserved for Future Issuance
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Options granted in period, weighted-average grant date fair value (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Schedule of Stock-Based Compensation Expense for Stock Awards Recognized
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised
Stock-Based Compensation Plans
Share-Based Payment Arrangement [Text Block]
Shares issued in connection with the Company's employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock (in shares)
Stock Issued During Period, Shares, New Issues
PEO
PEO [Member]
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents [Domain]
Number of monthly installments
Number Of Monthly Installments
Number Of Monthly Installments
Total
Share-Based Payment Arrangement, Expense
Repricing modification (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Repricing Modification in Period
Share-based Compensation Arrangement by Share-based Payment Award, Options, Repricing Modification in Period
Additional shares authorized (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized
Forgone Recovery due to Violation of Home Country Law, Amount
Forgone Recovery due to Violation of Home Country Law, Amount
Product Information [Line Items]
Product Information [Line Items]
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Exercise of employee stock options ( in shares)
Exercised (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Accumulated Deficit
Retained Earnings [Member]
Operating lease liabilities
Operating Lease, Liability, Noncurrent
Total operating expenses
Total operating expenses
Operating Expenses
Money market funds
Money Market Funds [Member]
Warrants and Tranche Rights
Stockholders' Equity, Policy [Policy Text Block]
Erroneously Awarded Compensation Recovery
Erroneously Awarded Compensation Recovery [Table]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Common stock, shares outstanding (in shares)
Beginning balance (in shares)
Ending balance (in shares)
Common Stock, Shares, Outstanding
Award Timing Disclosures [Line Items]
Net loss per share, diluted (in usd per share)
Earnings Per Share, Diluted
Entity Current Reporting Status
Entity Current Reporting Status
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Stock price volatility, maximum (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Total Shareholder Return Amount
Total Shareholder Return Amount
Aggregate royalty fee percentage
Class of Warrant or Right, Aggregate Royalty Fee Percentage
Class of Warrant or Right, Aggregate Royalty Fee Percentage
Clinical costs
Clinical Costs Payable, Current
Clinical Costs Payable, Current
Other current assets and prepaid expenses
Increase (Decrease) in Prepaid Expense and Other Assets
VAT receivable
Value Added Tax Receivable, Current
February 2026 PIPE Transaction
February 2026 P I P E Transaction [Member]
February 2026 P I P E Transaction
Research and development
Research and Development Expense
Placement Agency Agreement
Placement Agency Agreement [Member]
Placement Agency Agreement
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Share-Based Payment Arrangement [Abstract]
Property and equipment, net
Property, Plant, and Equipment, after Accumulated Depreciation, Depletion, and Amortization
2019 Omnibus Equity Incentive Plan
2019 Omnibus Equity Incentive Plan [Member]
2019 Omnibus Equity Incentive Plan [Member]
Retention Bonus payout period upon termination
Salary and Wage, Retention Bonus Agreement, Termination Payout Period
Salary and Wage, Retention Bonus Agreement, Termination Payout Period
May 2022 ATM
May 2022 ATM [Member]
May 2022 ATM
Exercisable, ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Exercise of employee stock options
Stock Issued During Period, Value, Stock Options Exercised
Equity Awards Adjustments, Footnote
Equity Awards Adjustments, Footnote [Text Block]
SARs granted (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted
Underlying Securities
Award Underlying Securities Amount
2019 and 2026 Inducement Plan
2019 and 2026 Inducement Plan [Member]
2019 and 2026 Inducement Plan
Issuance of common stock
Shares issued
Stock Issued During Period, Value, New Issues
Executive Chairman Agreement
Executive Chairman Agreement [Member]
Executive Chairman Agreement
Exercisable, ending balance (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Retention agreement, bonus
Salary and Wage, Retention Bonus Agreement
Salary and Wage, Retention Bonus Agreement
Risk-free interest rate, minimum (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Segment Reporting [Table]
Segment Reporting [Table]
Shares available for grant (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Schedule of Related Party Transactions, by Related Party [Table]
Related Party Transaction [Table]
Non-cash lease expense
Provision for Loan, Lease, and Other Losses
Title of Individual [Axis]
Title and Position [Axis]
Cash flows from investing activities:
Cash Provided by (Used in) Investing Activity, Continuing Operation [Abstract]
Sale of Stock [Axis]
Sale of Stock [Axis]
Weighted-Average Remaining Contractual Term and Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Shares reserved for SARs for unexercised Series B warrants
Unexercised Series B Warrants [Member]
Unexercised Series B Warrants
Other
Other Assets, Current
Number of existing leases
Lessee, Operating Leases, Number Of Existing Leases
Lessee, Operating Leases, Number Of Existing Leases
Cash flows from operating activities:
Cash Provided by (Used in) Operating Activity, Continuing Operation [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies Disclosure [Abstract]
All Trading Arrangements
All Trading Arrangements [Member]
Beginning balance
Ending balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Other Performance Measure, Amount
Other Performance Measure, Amount
Award Timing MNPI Considered
Award Timing MNPI Considered [Flag]
Loss from operations
Loss from operations
Operating Income (Loss)
SARs liability
Deferred Compensation Share-Based Arrangements, Liability, Current
Current Fiscal Year End Date
Current Fiscal Year End Date
Non-PEO NEO Average Total Compensation Amount
Non-PEO NEO Average Total Compensation Amount
Related Party Transaction [Domain]
Related Party Transaction [Domain]
2017 Inducement Equity Incentive Plan
2017 Inducement Equity Incentive Plan [Member]
2017 Inducement Equity Incentive Plan [Member]
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year
Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member]
Common stock, cash dividends paid (in usd per share)
Common Stock, Dividends, Per Share, Declared
Options to purchase common stock
Equity Option [Member]
Entity File Number
Entity File Number
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted [Flag]
Schedule of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Weighted- Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Recovery of Erroneously Awarded Compensation Disclosure [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Commission, percent of gross proceeds from sale of common stock (as a percent)
Sales of Stock, Commissions, Percent Of Gross Proceeds
Sales of Stock, Commissions, Percent Of Gross Proceeds
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Measure:
Measure [Axis]
Description of Business and Basis of Financial Statements
Business Description and Basis of Presentation [Text Block]
April 2025 And May 2025 Financing
April 2025 And May 2025 Financing [Member]
April 2025 And May 2025 Financing
Incremental expense
Share-Based Payment Arrangement, Plan Modification, Incremental Cost
Government assistance
Government Assistance [Policy Text Block]
Pre-clinical product candidates
Pre Clinical Product Candidates
Pre Clinical Product Candidates
Series A Warrant and Series B Warrant
Series A Warrant and Series B Warrant [Member]
Series A Warrant and Series B Warrant
Equity Components [Axis]
Equity Components [Axis]
Class of Stock [Line Items]
Class of Stock [Line Items]
Entity Interactive Data Current
Entity Interactive Data Current
Compensation Actually Paid vs. Other Measure
Compensation Actually Paid vs. Other Measure [Text Block]
Entity Small Business
Entity Small Business
Total comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Termination Date
Trading Arrangement Termination Date
Property, Plant, and Equipment [Line Items]
Property, Plant, and Equipment [Line Items]
Lump-sum payment, bonus
Salary and Wage, Lump-Sum Bonus Payment
Salary and Wage, Lump-Sum Bonus Payment
Germany
GERMANY
Subsequent Events [Abstract]
Subsequent Events [Abstract]
Fair Value Measurements, Recurring and Nonrecurring [Table]
Fair Value, Recurring and Nonrecurring [Table]
Compensation Actually Paid vs. Total Shareholder Return
Compensation Actually Paid vs. Total Shareholder Return [Text Block]
Reserve stock split (in shares)
Stockholders' Equity Note, Stock Split, Conversion Ratio
MNPI Disclosure Timed for Compensation Value
MNPI Disclosure Timed for Compensation Value [Flag]
Other current liabilities
Total
Other Liabilities, Current
Expiration period (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Collaboration Arrangements, Daiichi Sankyo Agreement and Ludwig-Maximilians-University Agreement
Collaborative Arrangement, Accounting Policy [Policy Text Block]
Cash flows from financing activities:
Cash Provided by (Used in) Financing Activity, Continuing Operation [Abstract]
Document Type
Document Type
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Accrued expenses
Accrued expenses
Accrued Liabilities, Current
Fair Value as of Grant Date
Award Grant Date Fair Value
Aggregate intrinsic value, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
December 2020 ATM
December 2020 ATM [Member]
December 2020 ATM
Prepaid clinical and related costs
Prepaid Clinical And Related Costs, Current
Prepaid Clinical And Related Costs, Current
Options exercisable, Aggregate Intrinsic Value, Ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Pay vs Performance Disclosure, Table
Pay vs Performance [Table Text Block]
Arrangement Duration
Trading Arrangement Duration
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Statement of Stockholders' Equity [Abstract]
Statement of Stockholders' Equity [Abstract]
Local Phone Number
Local Phone Number
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Registrant Name
Entity Registrant Name
Insider Trading Policies and Procedures Not Adopted
Insider Trading Policies and Procedures Not Adopted [Text Block]
Commitments and contingencies (Note 9)
Commitments and Contingencies
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Changed Peer Group, Footnote
Changed Peer Group, Footnote [Text Block]
Forgone Recovery due to Expense of Enforcement, Amount
Forgone Recovery due to Expense of Enforcement, Amount
Executive Category:
Executive Category [Axis]
Vesting period (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
April 2025 PIPE Transaction
April 2025 P I P E Transaction [Member]
April 2025 P I P E Transaction
Counterparty Name [Axis]
Counterparty Name [Axis]
Liabilities and Stockholders’ Equity (Deficit)
Liabilities and Equity [Abstract]
Other Commitments [Table]
Other Commitments [Table]
Australia
AUSTRALIA
Options exercisable, Weighted-Average Remaining Contractual Term, Ending balance (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term
Schedule of Financial Assets and Liabilities Measured at Fair Value on a Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Equity Award [Domain]
Award Type [Domain]
Shelf registration, termination, prior written notice (in days)
Shelf Registration, Termination, Prior Written Notice, Number of Days
Shelf Registration, Termination, Prior Written Notice, Number of Days
January 2024 PIPE Transaction
January 2024 P I P E Transaction [Member]
January 2024 P I P E Transaction
Non-PEO NEO Average Compensation Actually Paid Amount
Non-PEO NEO Average Compensation Actually Paid Amount
Shares issued from exercise of pre-funded warrants (in shares)
Class of Warrant or Right, Outstanding
2026
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
Fair Value
Fair Value Disclosures [Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
Number of financial institutions used for cash deposits
Number of Financial Institutions Used For Cash Deposits
Number of Financial Institutions Used For Cash Deposits
Expected term (years)
Expected term of options (years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Share price (in usd per share)
Share Price
Lease term (in months)
Lessee, Operating Lease, Term of Contract
PEO Name
PEO Name
Geographical [Axis]
Geographical [Axis]
Accrued expenses
Increase (Decrease) in Accrued Liabilities
Government R&D assistance rate (as a percent)
Government Assistance, Qualified Research and Development Expenditures, Percent
Government Assistance, Qualified Research and Development Expenditures, Percent
Repricing modifications (in usd per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Repricing Modifications Price
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Repricing Modifications Price
Stock Price or TSR Estimation Method
Stock Price or TSR Estimation Method [Text Block]
Consecutive business days
Debt Instrument, Convertible, Threshold Consecutive Business Days
Debt Instrument, Convertible, Threshold Consecutive Business Days
Entity Tax Identification Number
Entity Tax Identification Number
Other Commitments [Line Items]
Other Commitments [Line Items]
Leases [Table]
Lessee, Lease, Description [Table]
Exercised (in usd per share)
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Cash and cash equivalents, beginning of period
Cash and cash equivalents, end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Schedule of SAR's Activity
Share-Based Payment Arrangement, Stock Appreciation Right, Activity [Table Text Block]
Accounts payable
Increase (Decrease) in Accounts Payable
Accrued other
Other Accrued Liabilities, Current
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Aggregate Erroneous Compensation Not Yet Determined
Aggregate Erroneous Compensation Not Yet Determined [Text Block]
May 2025 Pre-Funded Warrants
Shares reserved for the May 2025 Pre-funded warrants
May 2025 Pre-Funded Warrants [Member]
May 2025 Pre-Funded Warrants
Material Terms of Trading Arrangement
Material Terms of Trading Arrangement [Text Block]
Non-NEOs
Non-NEOs [Member]
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year
Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member]
Operating and variable lease costs
Operating And Variable Leases, Cost
Operating And Variable Leases, Cost
Subsequent Event [Table]
Subsequent Event [Table]
Stock-based compensation
Non-cash stock compensation
Share-Based Payment Arrangement, Noncash Expense
Employee costs
Labor and Related Expense
2026 Inducement Equity Compensation Plan
2026 Inducement Equity Compensation Plan [Member]
2026 Inducement Equity Compensation Plan
Exercise of warrants (in shares)
Stock Issued During Period, Shares, Conversion of Convertible Securities
Leases
Lessee, Operating Leases [Text Block]
Net loss per share, basic (in usd per share)
Earnings Per Share, Basic
Total current assets
Assets, Current
Range [Axis]
Statistical Measurement [Axis]
Insider Trading Arrangements [Line Items]
2019 Omnibus Equity Incentive Plan
Two Thousand Nineteen Omnibus Equity Incentive Plan [Member]
Two Thousand Nineteen Omnibus Equity Incentive Plan
Accrued clinical and related costs
Accrued Clinical Costs, Current
Accrued Clinical Costs, Current
Award Type [Axis]
Award Type [Axis]
Named Executive Officers, Footnote
Named Executive Officers, Footnote [Text Block]
Issuance of pre-funded warrants
Adjustments to Additional Paid in Capital, Warrant Issued
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table
Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member]
Awards Close in Time to MNPI Disclosures
Awards Close in Time to MNPI Disclosures [Table]
Common Stock
Common Stock [Member]
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Maximum annual contributions per employee (as a percent)
Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent
Stock Appreciation Rights (SARs) Plan
Stock Appreciation Rights (SARs) Plan [Member]
Stock Appreciation Rights (SARs) Plan
Compensation Actually Paid vs. Company Selected Measure
Compensation Actually Paid vs. Company Selected Measure [Text Block]
Options issued (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
2026 Inducement Equity Incentive Plan
2026 Inducement Equity Incentive Plan [Member]
2026 Inducement Equity Incentive Plan
Cover [Abstract]
Expected dividend yield (as a percent)
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Equity Awards Adjustments
Equity Awards Adjustments [Member]
Proceeds from issuance, net of offering expenses
Proceeds From Issuance Of Common Stock, Net Of Offering Expenses
Proceeds From Issuance Of Common Stock, Net Of Offering Expenses
Reportable Segment
Reportable Segment [Member]
Reportable Segment
Total liabilities and stockholders’ equity (deficit)
Liabilities and Equity
Outstanding stock options
Employee Stock Option
Share-Based Payment Arrangement, Option [Member]
Segments [Axis]
Segments [Axis]
Other liabilities
Increase (Decrease) in Other Operating Liabilities
Additional 402(v) Disclosure
Additional 402(v) Disclosure [Text Block]
Related Party [Domain]
Related and Nonrelated Parties [Domain]
Plan Name [Axis]
Plan Name [Axis]
Tabular List, Table
Tabular List [Table Text Block]
Vesting [Axis]
Vesting [Axis]
Additional paid-in capital
Additional Paid in Capital
Other income (expense), net
Other income (expense)
Other Nonoperating Income (Expense)
Schedule of Accounts Payable and Accrued Expenses
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Name
Awards Close in Time to MNPI Disclosures, Individual Name
Reclassification of Stock Appreciation Rights ("SARs") liability to equity
Adjustments To Additional Paid In Capital, Reclassification Of Stock Appreciation Rights Liability To Equity
Adjustments To Additional Paid In Capital, Reclassification Of Stock Appreciation Rights Liability To Equity
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested
Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member]
Outstanding, beginning balance
Outstanding, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Schedule of Other Current Liabilities
Other Current Liabilities [Table Text Block]
General and administrative
General and Administrative Expense
Sale of stock, price per share (in usd per share)
Sale of Stock, Price Per Share
Exercise of warrants
Stock Issued During Period, Value, Conversion of Convertible Securities
Preferred stock, shares authorized (in shares)
Preferred Stock, Shares Authorized
Chief Medical Officer
Chief Medical Officer [Member]
Chief Medical Officer
Incentive stock options
Incentive Employee Stock Option [Member]
Incentive Employee Stock Option [Member]
Property, Plant, and Equipment [Table]
Property, Plant, and Equipment [Table]
Preferred stock, $0.0001 par value; 20,000,000 shares authorized and no shares issued or outstanding as of June 30, 2026 and December 31, 2025
Preferred Stock, Value, Issued
Adjustment to Compensation:
Adjustment to Compensation [Axis]
SARs forfeited or expired (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures and Expirations
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated [Flag]
Aggregate Erroneous Compensation Amount
Aggregate Erroneous Compensation Amount
Statement of Cash Flows [Abstract]
Statement of Cash Flows [Abstract]
Remaining salary period
Salary And Wage, Officer, Remaining Salary Period
Salary And Wage, Officer, Remaining Salary Period
General and Administrative Expenses
Selling, General and Administrative Expenses, Policy [Policy Text Block]
May 2024 ATM
May 2024 ATM [Member]
May 2024 ATM
May 2025 PIPE Transaction
May 2025 P I P E Transaction [Member]
May 2025 P I P E Transaction
Aggregate Available
Trading Arrangement, Securities Aggregate Available Amount
Total assets at fair value
Assets, Fair Value Disclosure
Reclassification of SARs liability to equity
Reclassification Of Stock Appreciation Rights Liability To Equity
Reclassification Of Stock Appreciation Rights Liability To Equity
Name
Measure Name
Sale of stock, remaining capacity
Sale Of Stock, Remaining Capacity
Sale Of Stock, Remaining Capacity
Accounts payable
Total
Accounts Payable, Current
Pay vs Performance Disclosure [Line Items]
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Pay vs Performance Disclosure
Pay vs Performance Disclosure [Table]
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Entity Filer Category
Entity Filer Category
Name
Trading Arrangement, Individual Name
Cash and cash equivalents
Cash and Cash Equivalent
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Company Selected Measure Amount
Company Selected Measure Amount
Beginning balance (in shares)
Ending balance (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Depreciation and amortization
Depreciation, Depletion and Amortization
Probability, occuring (as a percent)
Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Probability Rate, Liquidation Event Occurring Estimated
Share-Based Compensation Arrangement By Share-Based Payment Award, Fair Value Assumptions, Probability Rate, Liquidation Event Occurring Estimated
Number of employees
Entity Number of Employees
Entity Address, Address Line Two
Entity Address, Address Line Two
Schedule of Stock by Class [Table]
Stock, Class of Stock [Table]
Dr. Vitt
Dr. Vitt [Member]
Dr. Vitt
2019 Omnibus Equity Incentive Plan, Evergreen Provision
Two Thousand Nineteen Omnibus Equity Incentive Plan, Evergreen Provision [Member]
Two Thousand Nineteen Omnibus Equity Incentive Plan, Evergreen Provision
Current assets:
Assets, Current [Abstract]
Non-PEO NEO
Non-PEO NEO [Member]
Foreign Currency Translation and Presentation
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Entity Address, Address Line One
Entity Address, Address Line One
Operating lease right-of use asset obtained in exchange for lease obligation
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Depreciation expense
Depreciation, Nonproduction
Comprehensive Income (Loss)
Comprehensive Income, Policy [Policy Text Block]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Award Timing Method
Award Timing Method [Text Block]
Net change in cash and cash equivalents
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Forgone Recovery, Explanation of Impracticability
Forgone Recovery, Explanation of Impracticability [Text Block]
Stock price volatility, minimum (as a percent)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Tranche 3
Share-Based Payment Arrangement, Tranche Three [Member]
Net loss
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Erroneous Compensation Analysis
Erroneous Compensation Analysis [Text Block]
Statement [Table]
Statement [Table]
Tranche 2
Share-Based Payment Arrangement, Tranche Two [Member]
Proceeds from Issuance of Warrants
Proceeds from Issuance of Warrants
Restatement Determination Date:
Restatement Determination Date [Axis]
Proceeds from the exercise of employee stock options
Proceeds from Stock Options Exercised
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Potential additional Stock Appreciation Rights from Series B Warrants
Additional Stock Appreciation Rights from exercised Series B Warrants [Member]
Additional Stock Appreciation Rights from exercised Series B Warrants
Interest income
Interest income
Investment Income, Interest
Number of votes per each share of common stock
Number of Votes Per Each Share of Common Stock
Number of Votes Per Each Share of Common Stock
Options exercisable, ending balance (in usd per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Leases
Lessee, Leases [Policy Text Block]
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents [Axis]
Base salary period
Salary and Wage, Officer, Base Salary Period
Salary and Wage, Officer, Base Salary Period
Maximum aggregate offering price of common stock, preferred stock, warrants, debt securities, and/or units
Maximum Aggregate Offering Price Of Securities Under Shelf Registration
Maximum Aggregate Offering Price Of Securities Under Shelf Registration
Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value [Roll Forward]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Pension Benefits Adjustments, Footnote
Pension Benefits Adjustments, Footnote [Text Block]
Thereafter
Lessee Operating Lease Liability Payments Due After Year Two
Lessee Operating Lease Liability Payments Due After Year Two