v3.26.1
Stock-Based Compensation Plans - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 48 Months Ended
Jun. 29, 2026
$ / shares
shares
Mar. 10, 2026
shares
Feb. 17, 2026
shares
Jul. 07, 2025
tranche
$ / shares
shares
Jun. 04, 2025
shares
Mar. 04, 2024
shares
Jun. 28, 2023
shares
Aug. 01, 2021
shares
Apr. 25, 2021
shares
Jul. 31, 2019
shares
Jun. 30, 2026
USD ($)
shares
Jun. 29, 2026
USD ($)
$ / shares
Mar. 31, 2026
Jun. 30, 2025
USD ($)
Jun. 30, 2026
USD ($)
$ / shares
shares
Jun. 29, 2026
USD ($)
$ / shares
Jun. 30, 2025
USD ($)
$ / shares
Dec. 31, 2025
Dec. 31, 2023
shares
May 22, 2026
shares
May 19, 2026
shares
Apr. 24, 2026
shares
Mar. 13, 2026
shares
Feb. 12, 2026
shares
Jul. 31, 2025
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Total | $                     $ 6,782,000,000     $ 1,899,000,000 $ 11,248,000,000   $ 3,941,000,000                
Expected dividend yield                             0.00%                    
Incremental expense | $                             $ 900,000                    
Series A Warrants                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options exercisable, ending balance (in shares)       1,000,000                                          
Options issued (in shares)       8,666,667                                          
Series B Warrants                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options exercisable, ending balance (in shares)   200,000   1,000,000                                          
Expiration period (in years)                             10 years                    
Options issued (in shares)   23,077   8,666,667                                          
Warrant exercised (in shares)     5,108,700                                            
Grant-date fair value (in usd per share) | $ / shares $ 11.62                     $ 11.62       $ 11.62                  
Series B Warrants | Royalty Purchase Agreement                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Warrant exercised (in shares)     3,357,967               5,108,700       5,108,700                 5,108,700  
Shares reserved for the January 2024 Pre-funded stock warrants | Tranche 2                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options exercisable, ending balance (in shares)       500,000                                          
Options issued (in shares)       4,662,005                                          
Shares reserved for the January 2024 Pre-funded stock warrants | Tranche 3                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options exercisable, ending balance (in shares)       500,000                                          
Options issued (in shares)       4,662,005                                          
SARs liability                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Expected dividend yield                               0.00%   0.00%              
Authorized (in shares)       3,500,000                                         3,500,000
Options exercisable, ending balance (in usd per share) | $ / shares       $ 7.65                                          
Number of tranches | tranche       5                                          
Grant-date fair value (in usd per share) | $ / shares $ 8.60                     $ 8.60       $ 8.60                  
SARs liability | Series B Warrants                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options issued (in shares)     410,535                                            
Time based Stock Appreciation Rights                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options exercisable, ending balance (in shares)       500,000                                          
Expiration period (in years)                             10 years                    
Maximum | SARs liability                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Expected term of options (years)                               2 years 8 months 15 days   2 years 4 months 24 days              
Minimum | SARs liability                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Expected term of options (years)                               1 month 2 days   1 year              
2021 Employee stock purchase plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Maximum annual contributions per employee (as a percent)                 15.00%                                
Purchase price of the stock, at discount from market price at purchase date (as a percent)                 85.00%                                
Shares available for grant (in shares)           120,000     20,000                                
Additional shares authorized (in shares)           100,000                                      
Shares issued under the ESPP (in shares)               77,858                                  
Total | $                     $ 16,000     $ 22,000 $ 32,000   $ 48,000                
2019 Omnibus Equity Incentive Plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Shares available for grant (in shares)                   150,000                              
2019 Omnibus Equity Incentive Plan | Incentive stock options                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Vesting period (in years)                             4 years                    
2019 Omnibus Equity Incentive Plan | Maximum                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Expected term of options (years)                             10 years                    
2019 Omnibus Equity Incentive Plan | Maximum | Non-statutory options                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Vesting period (in years)                             4 years                    
2019 Omnibus Equity Incentive Plan | Minimum | Non-statutory options                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Vesting period (in years)                             3 years                    
2019 Omnibus Equity Incentive Plan, Evergreen Provision                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Additional shares authorized (in shares)                   490,000                 440,887            
Additional shares authorized (as a percent)                   4.00%                              
Increase in other share (in shares) 6,000,000       700,000 910,000 444,000                                    
2026 Inducement Equity Compensation Plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Shares available for grant (in shares)                                         1,250,000   3,000,000    
Stock options remaining (in shares)                     250,000       250,000                    
2026 Inducement Equity Compensation Plan | Chief Medical Officer                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Shares available for grant (in shares)                                           300,000      
2026 Inducement Equity Compensation Plan | Chief Executive Officer                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Shares available for grant (in shares)                                       1,000,000          
2019 and 2026 Inducement Plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Options granted in period, weighted-average grant date fair value (in usd per share) | $ / shares                             $ 11.73   $ 6.70                
2019 Omnibus Equity Incentive Plan And 2026 Inducement Plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Additional shares authorized (in shares)                     6,000,000                            
Expected term of options (years)                             5 years 9 months 18 days   5 years 10 months 28 days                
Expected dividend yield                             0.00%   0.00%                
Total unrecognized compensation expense | $                     $ 48,400,000       $ 48,400,000                    
Period over which compensation cost will be recognized (in years)                             3 years 4 months 24 days                    
Stock Appreciation Rights (SARs) Plan                                                  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                                  
Total | $                     900,000 $ 1,600,000     $ 2,800,000 $ 1,600,000                  
Total unrecognized compensation expense | $                     $ 3,900,000       $ 3,900,000                    
Period over which compensation cost will be recognized (in years)                         2 years 8 months 12 days