Shares reserved for future issuance at June 30, 2026 are as follows:


			Number of Shares
Common stock reserved for issuance for:
2021 Employee stock purchase plan			42,142
Shares reserved for the January 2024 Pre-funded stock warrants			858,015
Placement agent warrants			28,333
Outstanding stock options			6,150,494
Shares reserved for the May 2025 Pre-funded warrants			5,119,867
Shares reserved for Time based SARs			496,679
Shares reserved for SARs for exercised Series B warrants			23,077
Shares reserved for SARs for unexercised Series B warrants			384,694
Shares reserved for the May 2025 Series B warrants			3,357,967
Shares reserved for the February 2026 Pre-funded warrants			22,907,600
Shares reserved for the February 2026 common warrants			22,907,600
Common stock options available for future grant:
2017 Inducement Equity Incentive Plan			4,625
2019 Omnibus Equity Incentive Plan			3,790,399
2026 Inducement Equity Incentive Plan			250,000
Total common shares reserved for future issuance			66,321,492